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2.
MMWR Morb Mortal Wkly Rep ; 69(8): 207-211, 2020 Feb 28.
Artículo en Inglés | MEDLINE | ID: mdl-32106217

RESUMEN

In January 2018, the Wisconsin Department of Health Services, Division of Public Health (DPH), received a report of a culture-confirmed case of Legionnaires' disease. The patient, who was immunocompromised, had died at a local hospital 10 days after being admitted. DPH and an infection preventionist from the hospital investigated to determine the source of the infection and prevent additional cases. Because the case was suspected to be nosocomial, health care facility water samples were tested for Legionella. When these samples were negative, water sources in the patient's home were tested. These tested positive for Legionella pneumophila, and the bacteria remained after an attempt to remediate. The patient and home isolates were identified as L. pneumophila serogroup 3, sequence type 93, by whole-genome multilocus sequence typing. A second resident of the home did not become ill. This case highlights the potential for immunocompromised persons and others at risk for Legionnaires' disease to be exposed to Legionella through home water systems containing the bacteria and demonstrates the difficulty of home remediation. This case also illustrates the role of lower respiratory tract specimens in the identification of less common Legionella infections (e.g., L. pneumophila serogroup 3) and confirmation of the infection source.


Asunto(s)
Exposición a Riesgos Ambientales/efectos adversos , Vivienda , Legionella pneumophila/aislamiento & purificación , Enfermedad de los Legionarios/diagnóstico , Anciano , Resultado Fatal , Humanos , Legionella pneumophila/clasificación , Serotipificación , Wisconsin
3.
Am J Case Rep ; 20: 1956-1960, 2019 Dec 28.
Artículo en Inglés | MEDLINE | ID: mdl-31882569

RESUMEN

BACKGROUND Legionella pneumonia can be an aggressive form of pneumonia. However, it is rare in pregnant women, particularly in the peripartum period. To the best of our knowledge this is the only case of Legionella pneumonia with endometrial sepsis. We are reporting a patient with this rare condition. CASE REPORT The patient was an 18-year-old female, pregnant with her first baby, who developed symptoms of the common cold near term. The patient was seen at another major facility initially and was discharged home with a diagnosis of "cold". She was still uncomfortable and came to our facility Aront Ogden Medical Center Elmira, NY, USA, where she had rupture of membranes and underwent C-section. She was suspected clinically of having pneumonia. Initial chest x-ray was negative, but computed tomography (CT)-scan did show bilateral pneumonia. Further workup confirmed the diagnosis of Legionella pneumonia and was treated for that as well as for endometritis. She did require Intensive Care Unit (ICU) care during her hospital stay. The patient was seen and evaluated by multiple subspecialties, including Critical Care, Infectious Disease, and Gastroenterology subspecialties. The patient improved steadily, and was later discharged home in the care of her family with a healthy baby and was advised to follow up with her Primary Medical Provider as outpatient. CONCLUSIONS Legionella pneumonia in pregnancy may be more common than we think, and could be easily overlooked in that patient population, have to be in the back mind of medical provider. Overlooking diagnosis could lead to serious adverse consequences for these patients.


Asunto(s)
Enfermedad de los Legionarios/diagnóstico , Neumonía Bacteriana/diagnóstico por imagen , Neumonía Bacteriana/microbiología , Complicaciones Infecciosas del Embarazo/diagnóstico , Complicaciones Infecciosas del Embarazo/microbiología , Adolescente , Resfriado Común/diagnóstico , Errores Diagnósticos , Femenino , Humanos , Embarazo , Tomografía Computarizada por Rayos X
4.
BMJ Case Rep ; 12(6)2019 Jun 20.
Artículo en Inglés | MEDLINE | ID: mdl-31227570

RESUMEN

Legionnaires' disease is a recognised but rare cause of rhabdomyolysis. It can be further complicated with renal impairment. In this case report, we describe a previously healthy, semiactive 50-year-old man who within days was reduced to having periods of dyspnea after minutes of walking in addition to near fatal acute renal failure. He was found to have the rare triad of Legionella pneumonia, renal failure and rhabdomyolysis, which is associated with high morbidity and mortality. He was treated according to guidelines with azithromycin monotherapy and aggressive fluid hydration. 20 days after admission, the patient was walking independently and discharged home.


Asunto(s)
Enfermedad de los Legionarios/complicaciones , Neumonía/complicaciones , Rabdomiólisis/etiología , Lesión Renal Aguda/etiología , Antibacterianos/uso terapéutico , Azitromicina/uso terapéutico , Diagnóstico Diferencial , Humanos , Legionella pneumophila/aislamiento & purificación , Enfermedad de los Legionarios/diagnóstico , Enfermedad de los Legionarios/tratamiento farmacológico , Enfermedad de los Legionarios/microbiología , Masculino , Persona de Mediana Edad , Neumonía/diagnóstico , Neumonía/microbiología , Rabdomiólisis/microbiología , Rabdomiólisis/patología , Resultado del Tratamiento
5.
Intern Med ; 58(19): 2831-2834, 2019 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-31243196

RESUMEN

We herein report the case of a 62-year-old man diagnosed with Legionella pneumonia while engaged in recovery work in a flooded area after the Heavy Rain Event of July 2018 in Japan. The patient was intubated and maintained on mechanical ventilation and continuous hemodiafiltration. He was also administered antimicrobial therapy with ciprofloxacin and azithromycin. After 53 days in the hospital, he was discharged. It is important to recognize the risk of Legionella infection and to take measures to prevent it during recovery work that involves exposure to water and soil after a flood disaster.


Asunto(s)
Antibacterianos/uso terapéutico , Hemodiafiltración/métodos , Enfermedad de los Legionarios/etiología , Desastres Naturales , Lluvia , Respiración Artificial/métodos , Humanos , Japón , Legionella pneumophila/aislamiento & purificación , Enfermedad de los Legionarios/diagnóstico , Enfermedad de los Legionarios/terapia , Masculino , Persona de Mediana Edad
6.
Emerg Infect Dis ; 25(6): 1218-1219, 2019 06.
Artículo en Inglés | MEDLINE | ID: mdl-31107214

RESUMEN

We report national surveillance of Legionnaires' disease in China. Urine samples from 11 (3.85%) of 286 patients with severe pneumonia of unknown cause were positive for the Legionella pneumophila serogroup 1 antigen. We isolated Legionella strains from 7 patients. Improved diagnostic testing is needed for this underestimated disease in China.


Asunto(s)
Legionella pneumophila , Enfermedad de los Legionarios/epidemiología , Enfermedad de los Legionarios/microbiología , Adulto , Anciano , Antígenos Bacterianos/inmunología , China/epidemiología , Femenino , Humanos , Legionella pneumophila/clasificación , Legionella pneumophila/efectos de los fármacos , Legionella pneumophila/genética , Legionella pneumophila/inmunología , Enfermedad de los Legionarios/diagnóstico , Masculino , Pruebas de Sensibilidad Microbiana , Persona de Mediana Edad , Tipificación Molecular , Vigilancia en Salud Pública , Serogrupo , Adulto Joven
7.
Eur J Clin Microbiol Infect Dis ; 38(7): 1377-1382, 2019 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-31119574

RESUMEN

The objective of this study was to identify potential false-positive urine Legionella pneumophila (Legionella) enzyme immunoassay test results. A total of 107 consecutive patients with positive EIA tests were retrospectively analyzed over a 34-month period. Concurrent blood, urine, and sputum cultures, as well as chest radiographic findings, were reviewed in these patients. Twenty patients (19%) had no radiographic evidence of pulmonary disease despite a positive EIA test. In those 20 patients, 14 also had growth of non-Legionella bacteria. Of patients with an infiltrate or opacity on chest imaging, only 27 had Legionella sputum cultures obtained, with Legionella culture growth occurring in 7 (26%). Nine other patients had negative Legionella sputum cultures but the growth of another pathogenic organism in blood, sputum, and/or urine cultures. Pseudomonas aeruginosa was the most common organism isolated, found in 20% of patients in the entire cohort. Twenty-five patients (23%) were characterized as having probable false-positive Legionella urinary antigen EIA testing, and an additional 17 patients (16%) were characterized as having possible false-positive Legionella EIA tests. Our findings suggest that urine Legionella EIA tests may lead to a substantial number of cases being misdiagnosed as Legionaries' disease in patients with non-Legionella bacterial colonization or infection.


Asunto(s)
Antígenos Bacterianos/orina , Técnicas para Inmunoenzimas , Legionella pneumophila/aislamiento & purificación , Enfermedad de los Legionarios/diagnóstico , Enfermedad de los Legionarios/orina , Urinálisis , Antígenos Bacterianos/inmunología , Bacterias/aislamiento & purificación , Errores Diagnósticos , Reacciones Falso Positivas , Humanos , Estudios Retrospectivos , Sensibilidad y Especificidad , Esputo/microbiología , Tórax/diagnóstico por imagen , Tórax/microbiología
8.
J Infect Chemother ; 25(6): 407-412, 2019 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-30935766

RESUMEN

BACKGROUND: Community-acquired pneumonia (CAP) due to Legionella has a high mortality rate in patients who do not receive adequate antibiotic therapy. In a previous study, we developed a simple Legionella Score to distinguish patients with Legionella and non-Legionella pneumonia based on clinical information at diagnosis. In the present study, we validated this Legionella Score for the presumptive diagnosis of Legionella CAP. METHODS: This validation cohort included 109 patients with Legionella CAP and 683 patients with non-Legionella CAP. The Legionella Score includes six parameters by assigning one point for each of the following items: being male, absence of cough, dyspnea, C-reactive protein (CRP) ≥ 18 mg/dL, lactate dehydrogenase (LDH) ≥ 260 U/L, and sodium < 134 mmol/L. RESULTS: When the Legionella CAP and non-Legionella CAP were compared by univariate analysis, most of the evaluated symptoms and laboratory test results differed substantially. The six parameters that were used for the Legionella Score also indicated clear differences between the Legionella and non-Legionella CAP. All Legionella patients had a score of 2 points or higher. The median Legionella Scores were 4 in the Legionella CAP cases and 2 in the non-Legionella CAP cases. A receiver operating characteristics curve showed that the area under the curve was 0.93. The proposed best cutoff, total score ≥3, had sensitivity of 93% and specificity of 75%. CONCLUSION: Our Legionella Score was shown to have good diagnostic ability with a positive likelihood of 3.7 and a negative likelihood of 0.10.


Asunto(s)
Infecciones Comunitarias Adquiridas/diagnóstico , Legionella pneumophila/aislamiento & purificación , Enfermedad de los Legionarios/diagnóstico , Neumonía/diagnóstico , Adulto , Anciano , Proteína C-Reactiva/análisis , Estudios de Cohortes , Infecciones Comunitarias Adquiridas/sangre , Infecciones Comunitarias Adquiridas/microbiología , Femenino , Humanos , L-Lactato Deshidrogenasa/sangre , Enfermedad de los Legionarios/sangre , Enfermedad de los Legionarios/microbiología , Masculino , Persona de Mediana Edad , Neumonía/sangre , Neumonía/microbiología , Pronóstico , Curva ROC , Factores Sexuales
10.
Orv Hetil ; 160(6): 235-240, 2019 Feb.
Artículo en Húngaro | MEDLINE | ID: mdl-30730199

RESUMEN

The mortality of severe ARDS is almost 60%. Ventilation-associated lung-injury can be avoided by low-pressure, low-volume ventilation. Potential use of ECMO in case of refractory hypoxemia beside modern ventilatory therapy can be considered. Increasing numbers of respiratory ECMO runs are seen worldwide, though the efficacy remains controversial. The authors present the first successful venovenous-ECMO treatment in severe ARDS in our Institute. We report the case of a 67-year-old male who was admitted with community-acquired pneumonia caused by Legionella. Despite empirical and later targeted antibiotic therapy, severe ARDS with sepsis evolved. Neither ventilation nor prone position resulted in permanent improvement in oxygenation. The patient was referred to our Institute for extracorporeal life support (ECLS) therapy. On admission, blood gas showed severe hypoxemia with mild hypercapnia (PaO2/FiO2: 60, pCO2: 53 mmHg at PEEP: 14 mmHg, PIP: 45 mmHg). X-ray showed bilateral patchy infiltrates while cardiac impairment (EF: 45%) and dilated right ventricle were seen on echocardiography. Elevated pulmonary artery pressure (mPAP: 41 mmHg) was measured. After implantation of femoral-jugular VV ECMO, oxygen saturation was appropriate with lung protective ventilation (FiO2: 0.5, TV: 3-4 ml/kg). Improving lung function enabled us to stop ECMO after 8 days and further 5 days later the patient was weaned off ventilation. After 21 days of intensive care we discharged him to the referral hospital. By reporting this case we emphasise the potential role of respiratory ECMO. Consideration should be given to increase the contingent of this modality in the Hungarian intensive care in accordance with international practice. Orv Hetil. 2019; 160(6): 235-240.


Asunto(s)
Oxigenación por Membrana Extracorpórea/métodos , Enfermedad de los Legionarios/terapia , Neumonía/terapia , Síndrome de Dificultad Respiratoria del Adulto/terapia , Anciano , Humanos , Enfermedad de los Legionarios/diagnóstico , Masculino , Neumonía/microbiología , Síndrome de Dificultad Respiratoria del Adulto/microbiología , Resultado del Tratamiento
12.
Expert Rev Anti Infect Ther ; 17(2): 107-115, 2019 02.
Artículo en Inglés | MEDLINE | ID: mdl-30618315

RESUMEN

INTRODUCTION: Community-acquired pneumonia (CAP) continues to be a leading cause of hospitalization and mortality worldwide. Streptococcus pneumoniae and Legionella pneumophila remain the major etiological agents and are responsible for a significant proportion of CAP mortality. Among diagnostic tests for CAP, urine antigen detection of S. pneumoniae and L. pneumophila is widely accepted due to the simplicity of collection and the rapidity of the test results. Areas covered: This comprehensive review outlines the urinary antigen tests available, discusses their sensitivity and specificity, and assesses the usefulness of their results as the basis for targeted therapy. Expert commentary: There have been advances in urine antigen detection tests for patients with CAP. New methodologies show greater sensitivity, detect S. pneumoniae and L. pneumophila in a single test, and also detect pneumococcal serotypes. In addition, urine antigen detection tests have shown a high specificity, which means that a positive result practically indicates the causative pathogen of CAP. Therefore, a positive result can lead to a targeted therapy that is likely to improve patient outcomes and reduce the risk of resistance and adverse events. However, well-designed studies are needed to evaluate the usefulness of urine antigen detection tests with regard to clinical outcomes.


Asunto(s)
Antígenos Bacterianos/orina , Infecciones Comunitarias Adquiridas/diagnóstico , Neumonía Bacteriana/diagnóstico , Adulto , Antibacterianos/administración & dosificación , Antibacterianos/farmacología , Infecciones Comunitarias Adquiridas/microbiología , Farmacorresistencia Bacteriana , Hospitalización , Humanos , Legionella pneumophila/aislamiento & purificación , Enfermedad de los Legionarios/diagnóstico , Enfermedad de los Legionarios/microbiología , Neumonía Bacteriana/microbiología , Neumonía Neumocócica/diagnóstico , Neumonía Neumocócica/microbiología , Sensibilidad y Especificidad , Streptococcus pneumoniae/aislamiento & purificación
13.
Int J Hyg Environ Health ; 222(2): 315-318, 2019 03.
Artículo en Inglés | MEDLINE | ID: mdl-30501994

RESUMEN

In Germany community-acquired Legionnaires' disease is usually caused by the species Legionella pneumophila. Recurrent cases of Legionnaires' disease are rarely reported and are due either to a second infection (reinfection) or a relapse of a previous case. We report a case of recurrent Legionnaires' disease in an 86-year-old female patient infected with Legionella pneumophila serogroup 1, monoclonal antibody-subtype Knoxville, sequence type unknown. Between the two disease incidents the patient had completely recovered. Legionella pneumophila was detected with the monoclonal antibody-subtype Knoxville, sequence type 182, in the drinking water of the patient's apartment. Exposure to contaminated drinking water was interrupted after the first incident exposure through the application of point-of-use water filters. The filters were later removed due to low water pressure, and the second illness occurred thereafter. It is unclear if immunological predisposition has contributed to this case of probable reinfection of Legionnaires' disease. Clinical, microbiological and epidemiological information combined suggest this is a case of reinfection of Legionnaires' disease. In cases of recurrent Legionnaires' disease complete collection of patient and water samples is necessary to differentiate relapse from reinfection cases, to implicate the source of infection and to gain more evidence for the role of immunological predisposition.


Asunto(s)
Legionella pneumophila/aislamiento & purificación , Enfermedad de los Legionarios/diagnóstico , Anciano de 80 o más Años , Anticuerpos Monoclonales/inmunología , Antígenos Bacterianos/inmunología , Antígenos Bacterianos/orina , Femenino , Humanos , Legionella pneumophila/inmunología , Enfermedad de los Legionarios/microbiología , Enfermedad de los Legionarios/mortalidad , Microbiología del Agua , Abastecimiento de Agua
15.
Disaster Med Public Health Prep ; 13(2): 372-374, 2019 04.
Artículo en Inglés | MEDLINE | ID: mdl-29716666

RESUMEN

Geographic information systems (GIS) have emerged in the past few decades as a technology capable of assisting in the control of infectious disease outbreaks. A Legionnaires' disease cluster investigation in May 2016 in Sydney, New South Wales (NSW), Australia, demonstrated the importance of using GIS to identify at-risk water sources in real-time for field investigation to help control any immediate environmental health risk, as well as the need for more staff trained in the use of this technology. Sydney Local Health District Public Health Unit (PHU) subsequently ran an exercise (based on this investigation) with 11 staff members from 4 PHUs across Sydney to further test staff capability to use GIS across NSW. At least 80% of exercise participants reported that the scenario progression was realistic, assigned tasks were clear, and sufficient data were provided to complete tasks. The exercise highlighted the multitude of geocoding applications and need for inter-operability of systems, as well as the need for trained staff with specific expertise in spatial analysis to help assist in outbreak control activity across NSW. Evaluation data demonstrated the need for a common GIS, regular education and training, and guidelines to support the collaborative use of GIS for infectious disease epidemiology in NSW. (Disaster Med Public Health Preparedness. 2019;13:372-374).


Asunto(s)
Sistemas de Información Geográfica/instrumentación , Enfermedad de los Legionarios/diagnóstico , Brotes de Enfermedades/prevención & control , Brotes de Enfermedades/estadística & datos numéricos , Sistemas de Información Geográfica/tendencias , Humanos , Control de Infecciones/métodos , Enfermedad de los Legionarios/epidemiología , Nueva Gales del Sur/epidemiología , Salud Pública/instrumentación , Salud Pública/métodos , Salud Pública/tendencias
16.
J Microbiol Immunol Infect ; 52(3): 465-470, 2019 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-28964650

RESUMEN

BACKGROUND/PURPOSE: Legionella pneumophila had been recognized as an important pathogen for community-acquired pneumonia. We aimed to investigate clinical features and outcomes of patients with Legionnaires' disease at a tertiary medical center in northern Taiwan. METHODS: From June 2012 to February 2017, a retrospective review of adult community-acquired. Legionnaires' disease at a medical center was conducted. All Legionella infections were confirmed by positive urinary Legionella antigen assay, sera indirect immunofluorescence assay, or sputum culture for Legionella. Literature review of Legionnaires' disease from Medline and PubMED websites was performed. RESULTS: A total of 32 cases of Legionnaires' disease were identified. Their mean age was 64.3 years, with male predominance (27 cases, 84.3%). The underlying diseases were varied and most were attributed to chronic disorders, such as diabetes mellitus (31%) and cigarette smoking (40.6%). The most common symptoms were cough (68%) and fever (59.3%). More than half of patients (18, 56.2%) with Legionnaires' disease could initially present with extrapulmonary manifestations. Sixteen (50%) patients had delay in initiation of appropriate antibiotic therapy. Patients without adequately initiation of appropriate antibiotic therapy had higher proportion (11 of 16, 68.7%) of intensive care unit admission than patients with adequate initiation (5 of 16, 31.2%). Our results inferred that a delay in treatment might result in worsening of disease severity and the need for more intensive management. Overall mortality rate was 21.8%. Development of vasopressor requirement is an independent risk factor associated with mortality. CONCLUSION: Legionnaires' disease in Taiwan frequently present with extrapulmonary manifestations. Patients with hemodynamic instability that need vasopressor therapy associated with mortality.


Asunto(s)
Infecciones Comunitarias Adquiridas/epidemiología , Legionella pneumophila/aislamiento & purificación , Enfermedad de los Legionarios/epidemiología , Antibacterianos/uso terapéutico , Infecciones Comunitarias Adquiridas/diagnóstico , Infecciones Comunitarias Adquiridas/tratamiento farmacológico , Infecciones Comunitarias Adquiridas/microbiología , Femenino , Mortalidad Hospitalaria , Hospitalización/estadística & datos numéricos , Humanos , Enfermedad de los Legionarios/diagnóstico , Enfermedad de los Legionarios/tratamiento farmacológico , Enfermedad de los Legionarios/microbiología , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Factores de Riesgo , Taiwán/epidemiología , Centros de Atención Terciaria , Tiempo de Tratamiento
17.
Euro Surveill ; 23(50)2018 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-30563592

RESUMEN

AimTo evaluate real-time PCR as a diagnostic method for Legionnaires' disease (LD). Detection of Legionella DNA is among the laboratory criteria of a probable LD case, according to the European Centre for Disease Prevention and Control, although the utility and advantages, as compared to culture, are widely recognised.MethodsTwo independent laboratories, one using an in-house and the other a commercial real-time PCR assay, analysed 354 respiratory samples from 311 patients hospitalised with pneumonia between 2010-15. The real-time PCR reliability was compared with that of culture and urinary antigen tests (UAT). Concordance, specificity, sensitivity and positive and negative predictive values (PPV and NPV, respectively) were calculated.ResultsOverall PCR detected eight additional LD cases, six of which were due to Legionella pneumophila (Lp) non-serogroup 1. The two real-time PCR assays were concordant in 99.4% of the samples. Considering in-house real-time PCR as the reference method, specificity of culture and UAT was 100% and 97.9% (95% CI: 96.2-99.6), while the sensitivity was 63.6% (95%CI: 58.6-68.6) and 77.8% (95% CI: 72.9-82.7). PPV and NPV for culture were 100% and 93.7% (95% CI: 91.2-96.3). PPV and NPV for UAT were 87.5% (95% CI: 83.6-91.4) and 95.8% (95% CI: 93.5-98.2).ConclusionRegardless of the real-time PCR assay used, it was possible to diagnose LD cases with higher sensitivity than using culture or UAT. These data encourage the adoption of PCR as routine laboratory testing to diagnose LD and such methods should be eligible to define a confirmed LD case.


Asunto(s)
Legionella pneumophila/genética , Legionella pneumophila/aislamiento & purificación , Enfermedad de los Legionarios/diagnóstico , Reacción en Cadena en Tiempo Real de la Polimerasa/métodos , Humanos , Legionella pneumophila/inmunología , Reproducibilidad de los Resultados , Estudios Retrospectivos , Sensibilidad y Especificidad
18.
Indian J Med Microbiol ; 36(3): 324-333, 2018.
Artículo en Inglés | MEDLINE | ID: mdl-30429383

RESUMEN

Legionella pneumophila was first recognised as a fatal cause of pneumonia more than four decades ago, during the 1976-American Legion convention in Philadelphia, USA. Legionella spp. continue to cause disease outbreaks of public health significance, and at present, Legionnaires' disease (LD) has emerged as an important cause of community and hospital-acquired pneumonia. Parallel to this, the understanding of LD has also increased exponentially. However, the disease is likely to be underreported in many countries because of the dearth of common definitions, diagnostic tests and active surveillance systems. In this review, we outline the basic concepts of Legionella including clinical presentations, epidemiology, laboratory diagnosis and the status of LD in India. This article also summarises the progress of research related to Legionella in this country, identifying the research gaps and discussing priorities to explore this unexplored pathogen in India.


Asunto(s)
Legionella pneumophila/aislamiento & purificación , Enfermedad de los Legionarios/epidemiología , Investigación Biomédica/tendencias , Técnicas de Laboratorio Clínico/métodos , Infecciones Comunitarias Adquiridas/diagnóstico , Infecciones Comunitarias Adquiridas/epidemiología , Infecciones Comunitarias Adquiridas/patología , Infección Hospitalaria/diagnóstico , Infección Hospitalaria/epidemiología , Infección Hospitalaria/patología , Humanos , India/epidemiología , Enfermedad de los Legionarios/diagnóstico , Enfermedad de los Legionarios/patología
19.
Infect Control Hosp Epidemiol ; 39(12): 1470-1472, 2018 12.
Artículo en Inglés | MEDLINE | ID: mdl-30293535

RESUMEN

In 2017, we surveyed 101 SHEA Research Network hospitals regarding Legionnaires' disease (LD). Of 29 respondents, 94% have or are developing a water management plan with varying characteristics and personnel engaged. Most LD diagnostic testing is limited to urine antigen testing. Many opportunities to improve LD prevention and diagnosis exist.


Asunto(s)
Infección Hospitalaria/prevención & control , Desinfección/métodos , Legionella/aislamiento & purificación , Enfermedad de los Legionarios/diagnóstico , Enfermedad de los Legionarios/prevención & control , Abastecimiento de Agua , Infección Hospitalaria/transmisión , Hospitales , Humanos , Legionella/patogenicidad , Enfermedad de los Legionarios/transmisión , Enfermedad de los Legionarios/orina , Medición de Riesgo , Encuestas y Cuestionarios , Estados Unidos
20.
J Natl Black Nurses Assoc ; 29(1): 44-50, 2018 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-30282132

RESUMEN

The water crisis in Flint, Michigan raised national awareness about lead- tainted drinking water, particularly its harm to children and pregnant and lactating women. However, according to recent findings, there may be another by-product of this man-made crisis. Failure to use anticorrosive material in the water, a practice mandated by the 1978 Clean Water Act, is being linked to an outbreak of Legionnaires' disease, an illness detrimental primarily to adults over 65 years of age. While Legionnaires' disease is relatively rare, it is also likely to remain undiagnosed. Clinicians, therefore, are urged to consider this diagnosis in adults with pneumonia that does not respond to typical antibiotic treatment, and in newborns with respiratory distress along with other non-typical symptoms as well as those who have had water births or who were exposed to ultrasonic, cool-mist humidification.


Asunto(s)
Brotes de Enfermedades , Enfermedad de los Legionarios/epidemiología , Diagnóstico Diferencial , Humanos , Enfermedad de los Legionarios/diagnóstico , Michigan/epidemiología , Abastecimiento de Agua/legislación & jurisprudencia , Abastecimiento de Agua/normas
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