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1.
Gene ; 807: 145948, 2022 Jan 10.
Artículo en Inglés | MEDLINE | ID: mdl-34481002

RESUMEN

BACKGROUNDS: To investigate associations of genetic and environmental factors with coronary artery disease (CAD), we collected medical reports, lifestyle details, and blood samples of 2113 individuals, and then used the polymerase chain reaction (PCR)-ligase detection reaction (LDR) to genotype the targeted 102 SNPs. METHODS: We adopted elastic net algorithm to build an association model that considered simultaneously genetic and lifestyle/clinical factors associated with CAD in Chinese Han population. RESULTS: In this study, we developed an all covariates-based model to explain the risk of CAD, which incorporated 8 lifestyle/clinical factors and a gene-score variable calculated from 3 significant SNPs (rs671, rs6751537 and rs11641677), attaining an area under the curve (AUC) value of 0.71. It was found that, in terms of genetic variants, the AA genotype of rs671 in the additive (adjusted odds ratio (OR) = 2.51, p = 0.008) and recessive (adjusted OR = 2.12, p = 0.021) models, the GG genotype of rs6751537 in the additive (adjusted OR = 3.36, p = 0.001) and recessive (adjusted OR = 3.47, p = 0.001) models were associated with increased risk of CAD, while GG genotype of rs11641677 in additive model (adjusted OR = 0.39, p = 0.044) was associated with decreased risk of CAD. In terms of lifestyle/clinical factors, the history of hypertension (unadjusted OR = 2.37, p < 0.001) and dyslipidemia (unadjusted OR = 1.82, p = 0.007), age (unadjusted OR = 1.07, p < 0.001) and waist circumference (unadjusted OR = 1.02, p = 0.05) would significantly increase the risk of CAD, while height (unadjusted OR = 0.97, p = 0.006) and regular intake of chicken (unadjusted OR = 0.78, p = 0.008) reduced the risk of CAD. A significantinteraction was foundbetween rs671 and dyslipidemia (the relative excess risk due to interaction (RERI) = 3.36, p = 0.05). CONCLUSION: In this study, we constructed an association model and identified a set of SNPs and lifestyle/clinical risk factors of CAD in Chinese Han population. By considering both genetic and non-genetic risk factors, the built model may provide implications for CAD pathogenesis and clues for screening tool development in Chinese Han population.


Asunto(s)
Adenilil Ciclasas/genética , Aldehído Deshidrogenasa Mitocondrial/genética , Enfermedad de la Arteria Coronaria/genética , beta-Caroteno 15,15'-Monooxigenasa/genética , Adenilil Ciclasas/metabolismo , Anciano , Aldehído Deshidrogenasa Mitocondrial/metabolismo , Algoritmos , Área Bajo la Curva , Grupo de Ascendencia Continental Asiática/genética , Estudios de Casos y Controles , China/epidemiología , Enfermedad de la Arteria Coronaria/fisiopatología , Femenino , Predisposición Genética a la Enfermedad , Humanos , Hipertensión/genética , Estilo de Vida , Masculino , Persona de Mediana Edad , Oportunidad Relativa , Polimorfismo Genético/genética , Factores de Riesgo , Circunferencia de la Cintura/genética , beta-Caroteno 15,15'-Monooxigenasa/metabolismo
2.
Biol Trace Elem Res ; 200(1): 49-58, 2022 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-33609234

RESUMEN

Nickel (Ni) is a frequently used metal in the production of many products, and Ni exposure occurs in humans through food, inhalation, and skin. Studies reported Ni as the most common allergen diagnosed in the serial patch test. The main purpose of our study was to determine the concentration of Ni and other elements in the urine samples of individuals with Ni-sensitivity and to determine the effect of lifestyle habits on these variables. This study was conducted with 388 participants; additionally, both Ni patch test and inorganic analysis (for 24 elements) method in urine with inductively coupled plasma-mass spectrometry (ICP-MS) were applied to all participants. Ninety-two (23.7%) of the participants were found to have nickel sensitivity with a mean urine concentration of 4.475 µg/g creatinine (median=4.260; SD=2.527). The urine nickel concentration was significantly different between female and male participants (p =0.001). We found a significant correlation between Ni and other metals alongside various element pairs. The mean urine Ni concentration of the individuals with a positive Ni sensitivity test result was not different from that of the participants without Ni sensitivity (4.475 vs 4.256 µg/g creatinine, respectively; p = 0.068). The high accuracy, recovery, and repeatability data obtained from the analyses indicate that this study is efficient and appropriate for the quantitative determination of nickel and other elements in urine samples. Ni-containing objects and Ni-rich foods should be of concern for individuals with hypersensitivity reactions to the element.


Asunto(s)
Metales , Níquel , Femenino , Hábitos , Humanos , Estilo de Vida , Masculino , Pruebas del Parche
3.
Probl Sotsialnoi Gig Zdravookhranenniiai Istor Med ; 29(Special Issue): 1298-1303, 2021 Aug.
Artículo en Ruso | MEDLINE | ID: mdl-34792881

RESUMEN

The aim of the study was to study the factorial conditionality of the state of health and the features of medical activity (MA) of patients with COVID-19 who were treated on an outpatient basis using telemedicine technologies. MATERIAL AND METHODS: The study of lifestyle factors (LS) and MA was conducted by an anonymous survey of 7,743 patients with COVID-19. The patients' health was assessed based on the study of the course of the underlying disease and the presence of concomitant diseases, which were detected in 24.3% of COVID-19 patients according to the data of copying information from medical records. RESULTS: It was revealed that the prevalence of tobacco smoking was 33.25 cases per 100 respondents, 45.4% of respondents were overweight, 75.6% of patients had a low level of physical activity, 68.2% and 53.8% of patients had low medical literacy and MA, respectively. It is established that the greatest impact on the health status of the patients interviewed was provided by the bio-social activity (Smoking) (h = 0.702; m = 0.0063; p = 0.0022), physical activity (h = 0.624; m = 0.0026; p < 0.001, health behavior (h = 0.527; m = 0.0030; p < 0.001) and health literacy (h = 0.532; m = 0.0028; p < 0.001). CONCLUSION: The studied risk factors affecting the health status of COVID-19 patients, most of which are manageable, should be taken into account when forming therapeutic and preventive measures.


Asunto(s)
COVID-19 , Telemedicina , Humanos , Estilo de Vida , Pacientes Ambulatorios , SARS-CoV-2
4.
Ann Palliat Med ; 10(10): 10425-10433, 2021 10.
Artículo en Inglés | MEDLINE | ID: mdl-34763488

RESUMEN

BACKGROUND: The purpose of this study was to compare the clinical efficacy and safety of post-treatment nursing intervention (NI) with routine nursing care (RC) of patients with cardiovascular disease (CVD). METHODS: PubMed, EMBASE, the Cochrane Library, the China National Knowledge database, and other databases were used to comprehensively evaluate post-treatment NI versus RC for patients with CVD. Review Manager 5.0 was used to assess the impact of the results in the selected articles. Forest map analysis, sensitivity analysis, and bias analysis were performed on the collected data. RESULTS: In total, eight studies met the inclusion criteria. The systolic blood pressure in the RC group was higher than that in the NI group (MD =-3.72, 95% CI: -4.64 to -2.80, P<0.00001, I2=92%). The diastolic blood pressure in the NI group was lower than that in the RC group (MD =-5.36, 95% CI: -6.55 to -4.16, P<0.00001, I2=96%). There was a significant difference in fasting blood glucose levels between the NI group and the RC group (MD =-5.00, 95% CI: -9.47 to -0.52, P=0.03, I2=88%). The total cholesterol in the NI group was lower than that in the RC group (MD =-9.99, 95% CI: -14.52 to -5.45, P<0.0001, I2=85%). The triglyceride value of the NI group was lower than that of the RC group, with significant heterogeneity (MD =-24.24, 95% CI: -26.25 to -22.23, P<0.0001, I2=96%). A sensitivity analysis and funnel plot indicated that the study was reliable and publication bias was limited. DISCUSSION: The results showed that the efficacy and safety of NI were superior to RC after treatment of CVD. NI is worth popularizing.


Asunto(s)
Enfermedades Cardiovasculares , Presión Sanguínea , Humanos , Estilo de Vida , Prevención Primaria , Triglicéridos
5.
BMC Res Notes ; 14(1): 416, 2021 Nov 18.
Artículo en Inglés | MEDLINE | ID: mdl-34794504

RESUMEN

OBJECTIVES: Hypertension is a prevalent chronic disease globally. A multifaceted combination of risk factors is associated with hypertension. Scientific literature has shown the association among individual and environmental factors with hypertension, however, a comprehensive database including demographic, environmental, individual attributes and nutritional status has been rarely studied. Moreover, an integrated spatial-epidemiological approach has been scarcely researched. Therefore, this study aims to provide and describe a geodatabase including individual-based and socio-environmental data related to people living in the city of Mashhad, Iran in 2018. DATA DESCRIPTION: The database has been extracted from the PERSIAN Organizational Cohort study in Mashhad University of Medical Sciences. The data note includes three shapefiles and a help file. The shapefile format is a digital vector storage format for storing geometric location and associated attribute information. The first shapefile includes the data of population, air pollutants and amount of available green space for each census block of the city. The second shapefile consists of aggregated blood pressure data to the census blocks of the city. The third shapefile comprises the individual characteristics data (i.e., demographic, clinical, and lifestyle). Finally, the fourth file is a guide to the previous data files for users.


Asunto(s)
Contaminación del Aire , Parques Recreativos , Contaminación del Aire/estadística & datos numéricos , Presión Sanguínea , Estudios de Cohortes , Exposición a Riesgos Ambientales/estadística & datos numéricos , Humanos , Estilo de Vida
6.
BMC Neurol ; 21(1): 454, 2021 Nov 19.
Artículo en Inglés | MEDLINE | ID: mdl-34794413

RESUMEN

BACKGROUND: Anaemia has been reported to be associated with cognitive decline and Alzheimer's disease (AD), but the associations between anaemia and cerebrospinal fluid (CSF) AD biomarkers are still unknown. This study aimed to investigate the associations between anaemia and CSF AD biomarkers. METHODS: Participants were included from the Chinese Alzheimer's Biomarker and LifestylE (CABLE) study. The associations of anaemia and its severity with CSF AD biomarkers including ß-amyloid 1-42 (Aß42), total tau (t-tau) and phosphorylated tau (p-tau) were analysed by multiple linear regression models. Adjusted for age, gender, educational levels, APOE ε4 alleles, comorbidities (history of coronary heart disease, history of stroke, hypertension, diabetes mellitus, dyslipidaemia) and glomerular filtration rate. RESULTS: A total of 646 cognitively normal older adults, consisting of 117 anaemia patients and 529 non-anaemia individuals, were included in this study. Anaemia patients had lower levels of CSF Aß42 than individuals without anaemia (p = 0.035). Besides, participants with more severe anaemia had lower CSF Aß42 levels (p = 0.045). No significant association of anaemia with CSF t-tau and p-tau levels was found. CONCLUSION: Cross-sectionally, anaemia was associated with lower CSF Aß42 levels. These findings consolidated the causal close relationship between anaemia and AD.


Asunto(s)
Enfermedad de Alzheimer , Anemia , Anciano , Péptidos beta-Amiloides , Biomarcadores , Humanos , Estilo de Vida , Fragmentos de Péptidos , Proteínas tau
7.
BMC Public Health ; 21(1): 1974, 2021 11 01.
Artículo en Inglés | MEDLINE | ID: mdl-34724917

RESUMEN

BACKGROUND: Countrywide lockdown or stay-at-home order has been implemented to slow down the transmission of emergent coronavirus. However, the influence on attitudes and lifestyle due to lockdown amidst the coronavirus disease 2019 (COVID-19) pandemic has been poorly understood. The present study aimed to investigate the influence on attitudes and lifestyle due to lockdown amidst the COVID-19 pandemic among Bangladeshi residents. METHODS: A cross-sectional survey carried out involving 1635 community dwellers across eight divisions in Bangladesh conducted from April 15, 2020 to May 10, 2020. A structured questionnaire incorporating socio-demographic, attitudes towards lockdown and adverse lifestyle amidst lockdown measures was employed to collect data using the Google Forms. Multiple regression analyses were executed to determine the associated factors of positive attitudes towards lockdown and adverse lifestyle. RESULTS: The mean scores of attitudes towards lockdown were 67.9 (SD = 8.4) out of 85 with an overall correct rate (positive attitudes) of 79.9%; whereas the mean scores of adverse lifestyle amidst lockdown were 16.1 (SD = 4.8) out of 34 with an overall rate of 47.4%. The factors associated with more positive attitudes towards lockdown included being female, divorced, higher educated, and students. Conversely, being male, having no formal education, and rural residence were associated factors of adverse lifestyle amidst the COVID-19 pandemic. CONCLUSIONS: The findings reflect how the COVID-19 lockdown has preciously impacted the attitudes, and lifestyle of Bangladeshi citizens, which will contribute to promoting appropriate measures during a subsequent zonal or complete lockdown.


Asunto(s)
COVID-19 , Pandemias , Actitud , Control de Enfermedades Transmisibles , Estudios Transversales , Femenino , Humanos , Estilo de Vida , Masculino , Percepción , SARS-CoV-2
8.
Stud Health Technol Inform ; 285: 193-198, 2021 Oct 27.
Artículo en Inglés | MEDLINE | ID: mdl-34734873

RESUMEN

Endometrial cancer (EC) is the most common gynecological tumor in high-income countries, and its incidence has increased over time. The most critical risk factor for EC is the long-term unopposed exposure to increased estrogens both exogenous and endogenous. Machine learning can be used as a promising tool to resolve longstanding challenges and support identification of the risk factors and their correlations before the clinical trials and make them more focused. In this paper we present the results of the research of the correlation analysis of Endometrial cancer risk factors. The study was performed with EC patients of the Almazov center in Saint-Petersburg, Russia. All women involved in the current study underwent radical surgical intervention due to EC. After initial cancer treatment, they were referred to the Almazov center outpatient specialists for follow-up visits. Many of them were readmitted of the inpatient clinic due to relapse. We extracted a variety of parameters related to lifestyle, dietary habits, socioeconomic, and reproductive features from the inpatient and outpatient databases of Almazov center. The medical records of the women with enough data were included in the study. Prediction of Progression-free survival (PFS) and overall survival (OS) were analyzed respectively. The AUC of ROC was calculated for PFS = 0.93 and for OS = 0.94.


Asunto(s)
Neoplasias Endometriales , Enfermedad Crónica , Dieta Vegetariana , Femenino , Humanos , Estilo de Vida , Recurrencia
9.
Front Public Health ; 9: 625640, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-34746067

RESUMEN

Background: The current COVID-19 coronavirus pandemic is an emergency on a global scale, with huge swathes of the population required to remain indoors for prolonged periods to tackle the virus. In this new context, individuals' health-promoting routines are under greater strain, contributing to poorer mental and physical health. Additionally, individuals are required to keep up to date with latest health guidelines about the virus, which may be confusing in an age of social-media disinformation and shifting guidelines. To tackle these factors, we developed Elena+, a smartphone-based and conversational agent (CA) delivered pandemic lifestyle care intervention. Methods: Elena+ utilizes varied intervention components to deliver a psychoeducation-focused coaching program on the topics of: COVID-19 information, physical activity, mental health (anxiety, loneliness, mental resources), sleep and diet and nutrition. Over 43 subtopics, a CA guides individuals through content and tracks progress over time, such as changes in health outcome assessments per topic, alongside user-set behavioral intentions and user-reported actual behaviors. Ratings of the usage experience, social demographics and the user profile are also captured. Elena+ is available for public download on iOS and Android devices in English, European Spanish and Latin American Spanish with future languages and launch countries planned, and no limits on planned recruitment. Panel data methods will be used to track user progress over time in subsequent analyses. The Elena+ intervention is open-source under the Apache 2 license (MobileCoach software) and the Creative Commons 4.0 license CC BY-NC-SA (intervention logic and content), allowing future collaborations; such as cultural adaptions, integration of new sensor-related features or the development of new topics. Discussion: Digital health applications offer a low-cost and scalable route to meet challenges to public health. As Elena+ was developed by an international and interdisciplinary team in a short time frame to meet the COVID-19 pandemic, empirical data are required to discern how effective such solutions can be in meeting real world, emergent health crises. Additionally, clustering Elena+ users based on characteristics and usage behaviors could help public health practitioners understand how population-level digital health interventions can reach at-risk and sub-populations.


Asunto(s)
COVID-19 , Pandemias , Humanos , Estilo de Vida , Salud Mental , Pandemias/prevención & control , SARS-CoV-2
10.
Artículo en Inglés | MEDLINE | ID: mdl-34769879

RESUMEN

Chronic disease places an enormous economic burden on both individuals and the healthcare system, and existing fee-for-service models of healthcare prioritize symptom management, medications, and procedures over treating the root causes of disease through changing health behaviors. Value-based care is gaining traction, and there is a need for value-based care models that achieve the quadruple aim of (1) improved population health, (2) enhanced patient experience, (3) reduced healthcare costs, and (4) improved work life and decreased burnout of healthcare providers. Lifestyle medicine (LM) has the potential to achieve these four aims, including promoting health and wellness and reducing healthcare costs; however, the economic outcomes of LM approaches need to be better quantified in research. This paper demonstrates proof of concept by detailing four cases that utilized an intensive, therapeutic lifestyle intervention change (ITLC) to dramatically reverse disease and reduce healthcare costs. In addition, priorities for lifestyle medicine economic research related to the components of quadruple aim are proposed, including conducting rigorously designed research studies to adequately measure the effects of ITLC interventions, modeling the potential economic cost savings enabled by health improvements following lifestyle interventions as compared to usual disease progression and management, and examining the effects of lifestyle medicine implementation upon different payment models.


Asunto(s)
Planes de Aranceles por Servicios , Costos de la Atención en Salud , Humanos , Estilo de Vida , Cuidados Paliativos , Investigación
11.
Front Public Health ; 9: 693332, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-34778165

RESUMEN

Poor sleep is a relatively common condition with possibly serious adverse health consequences. Lack of sleep affects the endocrine, immune, and nervous systems. In Cyprus, there is no information about the quality of sleep in the population. The goal of this study was to assess the quality of sleep in the Cypriot population and evaluate its association with multimorbidity. A representative sample of the adult population of Cyprus was selected in 2018-2019 among the five government-controlled municipalities of the Republic of Cyprus using stratified sampling. Data on sleep quality as well as on the presence of chronic, clinical, and mental health conditions were collected using a validated questionnaire. Diseases were classified according to the International Classification of Diseases, 10th Revision (ICD-10). A total of 1,140 Cypriot men and women over 18-years of age (range: 18-94) participated in the study. The median Pittsburgh sleep quality index score of the participants was 5 (first quartile = 3, third quartile = 7) with the maximum score being 17, which suggests that the Cypriot population has a relatively good quality of sleep overall, although, almost one-third of the study population had a poor quality of sleep. Women, residents of Paphos, and married people had a poorer quality of sleep (p < 0.05). Having a poor quality of sleep was associated with higher odds of multimorbidity (OR = 2.21, 95% CI: 1.55, 3.16), even after adjusting for demographics, socioeconomic, and lifestyle factors. Adopting good sleep habits could be beneficial and would potentially help reduce the risk of multimorbidity. Public health guidelines regarding the importance of sleep and its association with multimorbidity should be considered.


Asunto(s)
Trastornos Mentales , Multimorbilidad , Adulto , Estudios Transversales , Femenino , Humanos , Estilo de Vida , Masculino , Sueño
12.
Medicine (Baltimore) ; 100(41): e27487, 2021 Oct 15.
Artículo en Inglés | MEDLINE | ID: mdl-34731128

RESUMEN

ABSTRACT: Fatty pancreas (FP) is characterized by pancreatic fat accumulation and the subsequent development of pancreatic and metabolic complications. However, FP has not been categorized in the manual for abdominal ultrasound in cancer screening and health check-ups in Japan, and the pathology of FP has not been fully elucidated.Nine hundred and nineteen people who underwent a medical check-up had the severity of their pancreatic fat accumulation categorized after transabdominal ultrasonographic examination. The relationships between FP, lifestyle-related diseases, and fatty liver disease at this time were assessed using stratification analysis.The prevalence of FP was 46.8% (430/919). People with FP were more likely to be male and had higher prevalences of lifestyle-related diseases, including fatty liver disease. Men and women were similarly represented in each tertile of pancreas brightness. Older age; high waist circumference, triglyceride and glucose index, serum low-density lipoprotein-cholesterol, hepatic steatosis index; and low serum amylase were associated with the presence of severe FP. Moreover, the group with severe liver steatosis had a higher prevalence of FP and a higher pancreatic brightness score. Logistic regression analysis showed that individuals with liver steatosis were more likely to have severe FP.The severity of FP is associated with features of lifestyle-related diseases and the severity of liver steatosis. These findings suggest that high visceral fat content is associated with more severe fatty pancreas as a phenotype of ectopic fat accumulation, as well as fatty liver disease.


Asunto(s)
Grasa Intraabdominal/patología , Páncreas/patología , Enfermedades Pancreáticas/patología , Examen Físico/normas , Adulto , Anciano , Amilasas/sangre , Glucemia , LDL-Colesterol/sangre , Estudios Transversales , Hígado Graso/epidemiología , Femenino , Humanos , Grasa Intraabdominal/diagnóstico por imagen , Grasa Intraabdominal/metabolismo , Japón/epidemiología , Estilo de Vida , Masculino , Enfermedades Metabólicas/diagnóstico , Enfermedades Metabólicas/etiología , Persona de Mediana Edad , Enfermedades Pancreáticas/complicaciones , Enfermedades Pancreáticas/epidemiología , Fenotipo , Prevalencia , Índice de Severidad de la Enfermedad , Triglicéridos/sangre , Ultrasonografía/métodos , Circunferencia de la Cintura
13.
Artículo en Inglés | MEDLINE | ID: mdl-34770148

RESUMEN

Lifestyle medicine (LM) is a rapidly emerging clinical discipline that focuses on intensive therapeutic lifestyle changes to treat chronic disease, often producing dramatic health benefits. In spite of these well-documented benefits of LM approaches to provide evidence-based care that follows current clinical guidelines, LM practitioners have found reimbursement challenging. The objectives of this paper are to present the results of a cross-sectional survey of LM practitioners regarding lifestyle medicine reimbursement and to propose policy priorities related to the ability of practitioners to implement and achieve reimbursement for these necessary services. Results from a closed, online survey in 2019 were analyzed, with a total of n = 857 included in this analysis. Results were descriptively analyzed. This manuscript articulates policy proposals informed by the survey results. The study sample was 58% female, with median age of 51. A minority of the sample (17%) reported that all their practice was LM, while 56% reported that some of their practice was LM. A total of 55% of practitioners reported not being able to receive reimbursement for LM practice. Of those survey respondents who provided an answer to the question of what would make the practice of LM easier (n = 471), the following suggestions were offered: reimbursement overall (18%), reimbursement for more time spent with patients (17%), more support from leadership (16%), policy measures to incentivize health (13%), education in LM for practitioners (11%), LM-specific billing codes and billing knowledge along with better electronic medical record (EMR) capabilities and streamlined reporting/paperwork (11%), and reimbursement for the extended care team (10%). Proposed policy changes focus on three areas of focus: (1) support for the care process using a LM approach, (2) reimbursement emphasizing outcomes of health, patient experience, and delivering person-centered care, and (3) incentivizing treatment that produces disease remission/reversal. Rectifying reimbursement barriers to lifestyle medicine practice will require a sustained effort from health systems and policy makers. The urgency of this transition towards lifestyle medicine interventions to effectively address the epidemic of chronic diseases in a way that can significantly improve outcomes is being hindered by current reimbursement policies and models.


Asunto(s)
Personal de Salud , Estilo de Vida , Estudios Transversales , Femenino , Humanos , Masculino , Políticas , Encuestas y Cuestionarios
14.
J Community Health Nurs ; 38(4): 232-243, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-34787041

RESUMEN

Purpose: Despite numerous established benefits of exercise, many older adults do not get enough. The purpose of this study was to identify facilitators and barriers to physical activity/exercise; gain greater understanding of older adults' physical activity self-efficacy; and increase understanding of how to reduce sedentary behavior.Design: Cross-sectional descriptiveMethods: Quantitative with convenience sample of 66 older adultsFindings: Nearly one third of participants reported engaging in regular physical activity. They tended to have rather strong physical activity self-efficacy and limited barriers to being active.Conclusions: The sample had limited involvement in physical activity or exercise, despite feeling confident in their ability to be active. There could be additional barriers or motivating factors that are preventing them from being more active.Clinical Evidence: Honest and directed conversation about older adults' understanding and attitudes towards exercise, paired with an individualized plan tailored to their interests and lifestyle could help increase physical activity/exercise.


Asunto(s)
Ejercicio Físico , Estilo de Vida , Anciano , Actitud , Estudios Transversales , Humanos
15.
Cien Saude Colet ; 26(suppl 3): 4823-4834, 2021.
Artículo en Portugués | MEDLINE | ID: mdl-34787178

RESUMEN

This study investigated the perception of above ideal body weight among adolescents in the city of Recife, Brazil, and its association with anthropometric profile and lifestyle. A cross-sectional study was conducted with a sample of 2480 adolescents from the "Study of Cardiovascular Risks in Adolescents." The conceptual model also assessed demographic and socioeconomic variables. Body weight perception was analyzed by asking the question: "In your opinion, your current body weight is … ?" Answers included: below ideal, ideal and above ideal body weight. Statistics were identified using Poisson Regression analysis. The mean age was 14.7 years (SD = 1.6), 53.7% were female, and 70.7% were eutrophic according to the body mass index/age (BMI/A). Perception of body weight was answered by 48.8% of the adolescents. 36.8% and 63.2% saw themselves as below and above their ideal weight, respectively. After adjustments, the variables associated with the perception of body weight above the ideal (outcome variable) were the female sex, age 12 to 14 years, mother's schooling > 8 years, BMI/A in the ideal range, being postpubescent, having breakfast and meals with parents occasionally. Demographic, anthropometric and lifestyle variables were more likely to be associated with body weight perception above the ideal.


Asunto(s)
Imagen Corporal , Estilo de Vida , Adolescente , Índice de Masa Corporal , Peso Corporal , Brasil , Niño , Estudios Transversales , Femenino , Humanos
16.
Acta Biomed ; 92(5): e2021399, 2021 11 03.
Artículo en Inglés | MEDLINE | ID: mdl-34738562

RESUMEN

BACKGROUND AND AIM: COVID-19 pandemic determined a profound impact in everyday life and in routine follow-up of patients with type 1 diabetes (T1D). In this context, telemedicine represented an important tool to guarantee a regular care for these patients. Aim of our work was to assess metabolic control before and after lockdown in the cohort of T1D patients followed-up by our Service, to evaluate the impact of restrictive measures and of disease management through telemedicine. METHODS: This is a retrospective observational study. Subjects were enrolled among children, adolescents and young adults affected by T1D and followed at the Regional Paediatric Diabetology Centre of the University-Hospital of Parma, Italy. We collected data about age, gender, ethnicity, anthropometric measurements, duration of disease, type of blood glucose monitoring used, type of insulin administration, daily insulin requirement and metabolic control, assessed using capillary HbA1c. RESULTS: We enrolled 139 patients, mean age 13.9 years. During lockdown, we reported significantly more contacts through telemedicine between patients and medical team. Global glycol-metabolic control significantly improved, without differences in daily insulin requirement. Patients with a previous poor-controlled diabetes showed a greater improvement. Finally, mean weekly hours of physical activity decreased significantly, without worsening in BMI z-score. CONCLUSIONS: Our results show a global improvement in mean HbA1c, with a stronger result for patients with a previous non satisfactory control. In our setting, despite regulatory rules and physical and logistic limitations related to pandemic, no worsening of metabolic control has been shown for patients with type 1 diabetes.


Asunto(s)
COVID-19 , Diabetes Mellitus Tipo 1 , Telemedicina , Adolescente , Glucemia , Automonitorización de la Glucosa Sanguínea , Control de Enfermedades Transmisibles , Diabetes Mellitus Tipo 1/epidemiología , Control Glucémico , Humanos , Estilo de Vida , Pandemias , SARS-CoV-2 , Adulto Joven
17.
Pan Afr Med J ; 39: 202, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-34603583

RESUMEN

Introduction: hypertension (HTN) is the main risk factor for most morbidities of elderly subjects. The objective of this study was to identify the epidemiological and clinical characteristics of hypertension in octogenarians and to identify the factors associated with uncontrolled hypertension in this population. Methods: we used data collected in the outpatient cardiology department of the University Hospital of Sfax between 15th April 2019 and 15th May 2019 as part of the National Tunisian Registry of Hypertension. We included in our study patients aged 80 years or more with hypertension. We described the epidemiological and clinical profile of this population, and we studied the associations between uncontrolled hypertension and socio-demographic, lifestyle, clinical and therapeutic factors using logistic regression models. Results: we included 346 subjects (45.1% (n=156) male and 54.9% (n=190) female), with a mean age of 84.36 (SD 4.01) years. More than half of them had uncontrolled hypertension. Dyslipidemia was the most common cardiovascular risk factor found in 43.6 % (n=151) of patients followed by diabetes (35.5%, n=122). One-third of patients had a history of coronary artery disease and/or stroke. Renal failure and kalemia disorders were observed, respectively, in 12.1% (n=42) and 25.2% (n=40) of patients. In multivariate analysis, factors associated with uncontrolled hypertension (HTN) were male sex (adjusted odds ratio (aOR): 1.663, 95% confidence interval (CI): 1.045-2.647; p=0.032), diabetes (aOR: 1.66, 95%CI: 1.031-2.688; p=0.037,) and poor adherence to blood pressure (BP) medications (aOR: 1.960, 95%CI: 1.195-3.214; p=0.008). Conclusion: our results showed that more than half of octogenarian hypertensive patients did not reach the BP target and that poor adherence to BP medications was the main factor of uncontrolled HTN. In this population, the presence of other comorbidities and poor adherence to BP medications are very common. Systematic research for behaviors suggesting poor medication adherence should be a priority for physicians caring for these patients.


Asunto(s)
Antihipertensivos/administración & dosificación , Presión Sanguínea/efectos de los fármacos , Hipertensión/epidemiología , Cumplimiento de la Medicación/estadística & datos numéricos , Anciano de 80 o más Años , Estudios Transversales , Dislipidemias/epidemiología , Femenino , Humanos , Hipertensión/tratamiento farmacológico , Estilo de Vida , Masculino , Factores de Riesgo
18.
Pan Afr Med J ; 39: 206, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-34603587

RESUMEN

Introduction: type 2 diabetes mellitus has become a global public health crisis. The increment in the cases has contributed significantly to the parallel increase in the prevalence of overweight and obesity. This paper aimed to analyse the relationship between lipid profile, waist circumference and body mass index (BMI) with the glycaemic control of the diabetes patients in Kedah. Methods: a cross-sectional study was conducted, using the Kedah audit samples data extracted from the National Diabetes Registry (NDR) from the year 2014 to 2018. A total of 25,062 registered type 2 diabetes mellitus patients were selected using the inclusion and exclusion criteria from the registry. Only patients with complete data on their HbA1C, lipid profile, waist circumference and BMI were analysed using SPSS version 21. Results: the means for the age, BMI and waist circumference of the samples were 61.5 (±10.85) years, 27.3 (±5.05) kg/m2 and 89.46 (±13.58) cm, respectively. Poor glycaemic control (HbA1c>6.5%) was observed in 72.7% of the patients, with females having poorer glycaemic control. The BMI and waist circumference were found to be significantly associated with glycaemic control (P<0.001). The total cholesterol, triglycerides and low-density lipoproteins values showed positive correlation with glycaemic control (r = 0.178, 0.157, 0.145, p<0.001), while high-density lipoproteins values are negatively correlated (r = -0.019, p<0.001). Conclusion: implementing lifestyle changes such as physical activity and dietary modifications are important in the management of BMI, waist circumference and body lipids, which in turn results in improved glycaemic control.


Asunto(s)
Glucemia/metabolismo , Diabetes Mellitus Tipo 2/epidemiología , Hemoglobina A Glucada/metabolismo , Lípidos/sangre , Anciano , Índice de Masa Corporal , Estudios Transversales , Diabetes Mellitus Tipo 2/sangre , Femenino , Humanos , Estilo de Vida , Malasia , Masculino , Persona de Mediana Edad , Obesidad/epidemiología , Sobrepeso , Sistema de Registros , Circunferencia de la Cintura/fisiología
19.
Artículo en Inglés | MEDLINE | ID: mdl-34639710

RESUMEN

The aim of this study was to validate the Short Multidimensional Inventory Lifestyle Evaluation-Confinement (SMILE-C) in a Malaysian context. The SMILE-C, which is a respondent-generated instrument, was used to ask participants questions on their lifestyle during the COVID-19 pandemic. The indices of seven sub-scores were then calculated. A total of 121 university staff members completed the Malay version of the SMILE-C as well as instruments for measuring well-being, family life satisfaction, mindfulness and awareness, work engagement, and quality of life. The Cronbach's alpha values and Pearson correlation coefficients were satisfactory in this initial validation of the instrument. The SMILE-C showed positive correlations with all the variables being studied. The results supported the criterion-related validity and psychometric properties of the Malay version of the SMILE-C as an instrument for assessing lifestyle changes during the COVID-19 pandemic.


Asunto(s)
COVID-19 , Calidad de Vida , Humanos , Estilo de Vida , Malasia , Pandemias , Psicometría , Reproducibilidad de los Resultados , SARS-CoV-2 , Encuestas y Cuestionarios , Universidades
20.
Artículo en Inglés | MEDLINE | ID: mdl-34639852

RESUMEN

We analyze the dynamic changes in individuals' lifestyle during the COVID-19 outbreak and recovery period through a survey of 1061 Chinese households. Specifically, we are interested in individuals' bodyweight, time allocation and food choices. We find that COVID-19 is associated with weight gain, less time spent on exercise and more time on entertainment. The proportion of online food purchase and snack purchases also shows an upward trend. This study provides useful implications on the impact of COVID-19 and its associated lockdowns on individuals' lifestyle and offers foresights for countries in different stages of the pandemic. It explains how encouraging exercise, managing new food purchase venues, and reducing the intake of unhealthy food such as snacks may also need to be considered in dealing with the aftermath of COVID-19.


Asunto(s)
COVID-19 , Control de Enfermedades Transmisibles , Conducta Alimentaria , Preferencias Alimentarias , Humanos , Estilo de Vida , SARS-CoV-2 , Bocadillos
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