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1.
Food Chem ; 368: 130843, 2022 Jan 30.
Artículo en Inglés | MEDLINE | ID: mdl-34418692

RESUMEN

This works proposed a feasibility study on NIR spectroscopy and chemometrics-assisted color histogram-based analytical systems (CACHAS) to determine and authenticate the cassava starch content in wheat flour. Prediction results of partial least squares (PLS) achieved coefficient of correlation (rpred) of 0.977 and root mean square error of prediction (RMSEP) of 1.826 mg kg-1 for the certified additive-free wheat flour, while rpred of 0.995 and RMSEP of 1.004 mg kg-1 were obtained for the commercial wheat flour containing chemical additives. Additionally, Data-Driven Soft Independent Modelling of Class Analogy (dd-SIMCA) presented similar predictive ability using NIR and CACHAS for the certified wheat flour, authenticating all target samples, besides correctly recognizing samples that could represent a fraud. No satisfactory results were obtained for the commercial wheat flour. Therefore, NIR spectroscopy is more useful to offer definitive quantitative and qualitative analysis, while CACHAS can only provide an alternative preliminary analysis.


Asunto(s)
Harina , Manihot , Pan , Estudios de Factibilidad , Harina/análisis , Análisis de los Mínimos Cuadrados , Espectroscopía Infrarroja Corta , Almidón , Triticum
2.
Addict Behav ; 124: 107074, 2022 01.
Artículo en Inglés | MEDLINE | ID: mdl-34509787

RESUMEN

BACKGROUND: This pilot study aimed to test the feasibility of providing varenicline in combination with nicotine replacement therapy (NRT) and motivational interviewing (MI) to adult male smokers attending a clinic in a hostel for homeless people. METHODS: A single group pre- and post-treatment (12 weeks following intervention commencement) design with embedded process evaluation (at weekly counselling and fortnightly safety check-ins). Participants were 20 male smokers attending a health clinic within a homelessness service in Sydney, Australia, between December 2019 and March 2020. Participants set a target quit date 7-days post intervention commencement. Adverse events, self-reported abstinence, cigarettes per day, treatment adherence and acceptability of the study interventions were assessed 12 weeks post intervention commencement. Abstinence was biochemically verified. Results are complete cases. RESULTS: Retention was 65% at 12-weeks post-intervention commencement (n = 13). No related adverse events were reported. Three participants (15%) reported continuous abstinence. Two participants self-reported 30-day point prevalence abstinence (10%), confirmed by CO level. Participants who did not quit smoking (n = 10), reported a significant reduction in the number of cigarettes smoked per day (19.4 vs 4.7, p < .01). Cravings, withdrawal symptoms, and psychological distress significantly decreased from baseline to 12-week follow-up (all < 0.01). Adherence to the pharmacological interventions was good, most used combination NRT and varenicline. Adherence to the counselling sessions was low, attending three of 12 sessions. Both NRT and MI were rated as highly acceptable. Some participants expressed concerns about the safety of varenicline. CONCLUSIONS: The intervention was feasible and acceptable and associated with short-term smoking cessation and significant reductions in the number of cigarettes smoked-per-day.


Asunto(s)
Personas sin Hogar , Entrevista Motivacional , Cese del Hábito de Fumar , Adulto , Estudios de Factibilidad , Humanos , Masculino , Proyectos Piloto , Fumar , Dispositivos para Dejar de Fumar Tabaco , Vareniclina/uso terapéutico
3.
Spectrochim Acta A Mol Biomol Spectrosc ; 265: 120337, 2022 Jan 15.
Artículo en Inglés | MEDLINE | ID: mdl-34530201

RESUMEN

A rapid method based on three-dimensional synchronous fluorescence spectroscopy was developed for emulsion oxidation evaluation. This method was selected because of its high sensitivity to dissolved organic matter typically occurring in the lipid oxidation. Spectral signal and chemical reference measurements were recorded for each emulsion sample as input and output data for the model construction. Characteristic values were extracted from the spectral data by the application of parallel factor (PARAFAC) analysis. Partial least squares regression (PLSR) was then used to construct a regression model for the rapid determination of emulsion oxidation. The correlation coefficient of the calibration and prediction sets were used as the performance parameters for the PLSR models as follows: R = 0.929, 0.973 for emulsion samples stored at 25℃; R = 0.897, 0.903 for emulsion samples stored at 70℃. The overall results demonstrated that the fluorescence spectroscopy, coupled with PARAFAC and PLSR algorithms, could be successfully used as a rapid method for the emulsion oxidation evaluation.


Asunto(s)
Espectroscopía Infrarroja Corta , Calibración , Emulsiones , Estudios de Factibilidad , Análisis de los Mínimos Cuadrados , Espectrometría de Fluorescencia
4.
Environ Pollut ; 292(Pt A): 118256, 2022 Jan 01.
Artículo en Inglés | MEDLINE | ID: mdl-34606970

RESUMEN

Batch sorption of metformin hydrochloride (MET) onto a specially designed biochar mix consisting of both macro (MAC) and micro (MIC) algae, rice husk and pine sawdust was conducted. Pyrolysis of both MAC and MIC algae mixture was done followed by chemical activation with hydrogen-peroxide. Additionally, sorption of MET under the influence of pH was separately investigated. Batch studies of isotherms were well described by Freundlich model with high non-linearity and Freundlich exponent values ranged anywhere from 0.12 to 1.54. Heterogeneity of MET adsorption to the bonding sites was attributed to the surface functional groups of the modified biochar. Amongst the four biochars, the activated macroalgae biochar (MACAC) and microalgae biochar (MICAC) depicted favourable adsorption of MET with maximum adsorption at pH 7. Up to 76% of MET removal from the environment was obatained using the MACAC biochar. Scanning electron micrographs coupled with energy dispersive X-ray, as well as elemental analyses confirmed formation of oxygen containing surface functional groups due to activation strengthening chemisorption as the main sorption mechanism. Further, Fourier transform infra-red spectroscopy and other surface functional group analyses along with Zeta potential measurements reinforced our proposed sorption mechanism. Lowest zeta potential observed at pH 7 enhanced the electrostatic force of attraction for both the biochars. Negative zeta potential value of the biochars under different pH indicated potential of the biochars to adsorb other positively charged contaminants. From a techno-economic perspective, capital expenditure cost is not readily available, however, it is envisaged that production of pyrolyzed biochar from algal biomass could make the process economically attractive especially when the biochar could be utilised for high-end applications.


Asunto(s)
Metformina , Oryza , Contaminantes Químicos del Agua , Adsorción , Carbón Orgánico , Estudios de Factibilidad , Lignina , Contaminantes Químicos del Agua/análisis
5.
Chemosphere ; 286(Pt 3): 131942, 2022 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-34426265

RESUMEN

Radioactivity monitoring post-cold war has become more complex due to the nuclear fallout and the surge in use of radioactive materials. This requires novel methods to detect, trace and distinguish natural and anthropogenic radioactive sources in the environment. We explored the feasibility of using ZrSiO4 (Zircon), as a reference signature for radioactivity monitoring due to the unique phenomenon of metamictization. We investigated the variations in microstructural properties of Zircon samples collected from a proposed Uranium site to identify these signatures using analytical techniques such as Gamma-ray Spectroscopy, XRD and Raman spectrum analysis. Besides elevated levels of radioactivity, the samples exhibited distinct properties such as increased lattice parameters observed from the XRD analysis and dramatic broadening of A1g (439 cm-1) and B1g (1008 cm-1) vibrational modes in the Raman spectrum. Structural parameters were further analyzed by modeling the crystal from experimentally observed lattice parameters. Ab-initio calculations were then performed on the modeled structure providing more insight into the microstructural variations. Samples collected from proposed Uranium mines indicate an increase of 1.226% and 0.9389% in Si-O and Zr-O bond lengths of the Zircon crystal signifying the ongoing process of metamictization from radiation damage. By correlating radioactivity levels with the lattice parameters variations of the collected samples, the study establishes a linear relation between the degree of damage to a mineral's crystal structure and the amount of radioactivity. We propose to use the variations in damage found in a mineral's structure as a nuclear forensic signature for advanced assessment of accumulated radioactivity in a particular geographical location.


Asunto(s)
Elementos Radiactivos , Monitoreo de Radiación , Radiactividad , Contaminantes Radiactivos del Suelo , Uranio , Estudios de Factibilidad , Contaminantes Radiactivos del Suelo/análisis , Uranio/análisis
6.
Crit Care Nurs Q ; 45(1): 88-97, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-34818302

RESUMEN

As the progress of critical care medicine has improved the survival rate of critically ill patients, comorbidities and long-term health care have attracted people's attention. The terms "post-intensive care syndrome" (PICS) and "PICS-family" (PICS-F) have been used in non-neurocritical care populations, which are characterized by the cognitive, psychiatric, and physical sequelae associated with intensive care hospitalization of survivors and their families. An intensive care unit (ICU) diary authored by the patient's family members may alleviate the psychological distress of the patient and his or her family. This quality improvement project focused on the development and implementation of the pediatric intensive care unit (PICU) diary in the pediatric critical care setting. The project aims to evaluate the feasibility and the potential efficacy of the PICU diary, measured through parental acceptance and satisfaction. Seventeen families of critically ill children admitted to the PICU received the PICU diary during the implementation period. Twenty-four parents completed the weekly follow-up, and 15 subsequently completed the diary entry evaluation. The use of the diary in the PICU setting is feasible and considered beneficial by families of critically ill children.


Asunto(s)
Enfermedad Crítica , Unidades de Cuidado Intensivo Pediátrico , Niño , Cuidados Críticos , Familia , Estudios de Factibilidad , Femenino , Humanos , Masculino
7.
Bioresour Technol ; 343: 126155, 2022 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-34673195

RESUMEN

Rapidly exhausting fossil fuels combined with the ever-increasing demand for energy led to an ongoing search for alternative energy sources to meet the transportation, manufacturing, domestic and other energy demands of the grown population. Microalgae are at the forefront of alternative energy research due to their significant potential as a renewable feedstock for biofuels. However, microalgae platforms have not found a way into industrial-scale bioenergy production due to various technical and economic constraints. The present review provides a detailed overview of the challenges in microalgae production processes for bioenergy purposes with supporting techno-economic assessments related to microalgae cultivation, harvesting and downstream processes required for crude oil or biofuel production. In addition, biorefinery approaches that can valorize the by-products or co-products in microalgae production and enhance the techno-economics of the production process are discussed.


Asunto(s)
Microalgas , Biocombustibles , Biomasa , Estudios de Factibilidad
8.
Chemosphere ; 287(Pt 1): 131998, 2022 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-34450373

RESUMEN

The sulfur-based autotrophic denitrification (SAD) and the solid organic carbon-based denitrification processes are both efficient techniques to remove nitrate from wastewater, and the hydrogen ions generated by the SAD process would be consumed in the heterotrophic denitrification process. Therefore, it is possible to improve the denitrification capacity when the solid organic carbon was added into a SAD reactor. In this study, corncob powder and sawdust powder were selected as solid organic carbon sources, and the sulfur-based autotrophic denitrification integrated biomass-based heterotrophic denitrification system was formed (SBD). The laboratory and field experiments showed that SBD could shorten the start-up period, decrease the sulfate productivity, and maintain a good denitrification performance when treated wastewater. According to the field experiment results, when the HRT was 1 h, the effluent total nitrogen (TN) concentration was always lower than 15 mg L-1. In addition, nitrite inhibition was observed when the concentration of nitrite in the reactors reached above 30 mg L-1. The mixture of elemental sulfur powder, shell powder, corncob powder, and sawdust powder with a mass ratio of 6:2:1:1 was the optimal filter for the SBD system, with an average nitrate reduction rate (NAR) of 420 mg NO3-N·L-1·d-1 obtained at the end of the study. During the whole operation, the major autotrophs in the SBD systems were Thermomonas, Ferritrophicum, and Thiobacillus, while the major heterotrophs were Saprospiraceae, Ferruginibacter, Dokdonella, and Simplicispira. Overall, the SBD system was a feasible and practically favorable way to remove nitrate from wastewater.


Asunto(s)
Desnitrificación , Aguas Residuales , Procesos Autotróficos , Biomasa , Reactores Biológicos , Estudios de Factibilidad , Nitratos , Nitrógeno , Azufre
9.
J Wound Care ; 30(11): 940-944, 2021 Nov 02.
Artículo en Inglés | MEDLINE | ID: mdl-34747209

RESUMEN

OBJECTIVE: To test the feasibility of using a standardised data collection tool to estimate the cost of stage 2-4 pressure ulcer (PU) care within an acute care setting. METHOD: Data on resource use and cost were obtained through a retrospective survey of nursing and medical notes collecting cost data for individual patients who received care for stage 2-4 PUs. RESULTS: Data for 20 patients (12 male/8 female) were analysed. The average patient age was 69 years (range: 37-95 years). Of this sample, seven patients had hospital-acquired PUs (HAPUs) and 14 patients had community-acquired PUs (CAPU) (one patient had both-in different anatomical areas). Over half of the total sample (55%; n=11) had a stage 2 PU. The average length of stay was 31.8 days (range: 5-119 days). Most of the patients (70%; n=14) had a CAPU. The average cost per patient with PU care was €878 (range: €39-2393). The mean cost for patients with a HAPU was €866 (SD: €1313) versus €911 (SD: €567) for patients with a CAPU. The majority of the cost related to equipment and staff time for treatment. CONCLUSION: Overall, the application of the standardised data collection tool to obtain cost data from retrospective inspection of nursing and medical notes is feasible. The cost of PU care in this sample was high, indicating that these wounds may impose a substantial burden on health systems. The costs varied greatly between patients in the sample, reflecting the complexity of PU care. Furthermore, given that costs increased with the higher PU stages, there is a potential to reduce costs by preventing the development of higher stage PUs. Larger-scale studies are required to understand the cost variation and full economic impact of PU care. DECLARATION OF INTEREST: The authors have no conflicts of interest.


Asunto(s)
Úlcera por Presión , Adulto , Anciano , Anciano de 80 o más Años , Cuidados Críticos , Estudios de Factibilidad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Úlcera por Presión/terapia , Estudios Retrospectivos , Encuestas y Cuestionarios
10.
Medicine (Baltimore) ; 100(41): e27478, 2021 Oct 15.
Artículo en Inglés | MEDLINE | ID: mdl-34731126

RESUMEN

ABSTRACT: The COVID-19 pandemic has challenged institutions' diagnostic processes worldwide. The aim of this study was to assess the feasibility of an artificial intelligence (AI)-based software tool that automatically evaluates chest computed tomography for findings of suspected COVID-19.Two groups were retrospectively evaluated for COVID-19-associated ground glass opacities of the lungs (group A: real-time polymerase chain reaction positive COVID patients, n = 108; group B: asymptomatic pre-operative group, n = 88). The performance of an AI-based software assessment tool for detection of COVID-associated abnormalities was compared with human evaluation based on COVID-19 reporting and data system (CO-RADS) scores performed by 3 readers.All evaluated variables of the AI-based assessment showed significant differences between the 2 groups (P < .01). The inter-reader reliability of CO-RADS scoring was 0.87. The CO-RADS scores were substantially higher in group A (mean 4.28) than group B (mean 1.50). The difference between CO-RADS scoring and AI assessment was statistically significant for all variables but showed good correlation with the clinical context of the CO-RADS score. AI allowed to predict COVID positive cases with an accuracy of 0.94.The evaluated AI-based algorithm detects COVID-19-associated findings with high sensitivity and may support radiologic workflows during the pandemic.


Asunto(s)
Inteligencia Artificial/normas , COVID-19/diagnóstico , Pulmón/diagnóstico por imagen , Anciano , Anciano de 80 o más Años , COVID-19/epidemiología , Prueba de Ácido Nucleico para COVID-19/normas , Estudios de Factibilidad , Femenino , Humanos , Pulmón/patología , Masculino , Persona de Mediana Edad , Pandemias , Estudios Retrospectivos , SARS-CoV-2 , Tomografía Computarizada por Rayos X
11.
BMC Res Notes ; 14(1): 406, 2021 Nov 02.
Artículo en Inglés | MEDLINE | ID: mdl-34727972

RESUMEN

OBJECTIVE: Salivary cortisol and cortisone are used as biomarkers of physiological stress. Careful sampling of saliva for profiling of awakening response and the diurnal slope can be challenging in free-living environments, and validated sampling protocols are lacking. Therefore, we investigated (1) the level of compliance to a three-day home-based salivary sampling protocol, and (2) the within subject day-to-day variability of cortisol and cortisone outcomes and the required measuring days to obtain high reproducibility. RESULTS: Nineteen healthy adults (mean age: 42, 50% females) participated. Participants collected in total 434 salivary samples out of 456 scheduled (four samples per day over three consecutive days at two time points). We found high level of compliance to the proposed free-living salivary sampling protocol with 18 (95%) and 16 (84%) participants being compliant to numbers and timing of samples, respectively. The area under the curve for the morning salivary samples and peak-to-bed slope had moderate reproducibility for cortisol and cortisone (intraclass correlation coefficient: 0.51-0.68, and mean coefficient of variation: 14.7%-75.3%). Three-to-four measuring days were required for high reproducibility of the area under the curve for the morning salivary samples and peak-to-bed slope using this free-living salivary sampling protocol. Trial registration Clinical trial registered with www.clinicaltrials.gov (NCT03788525).


Asunto(s)
Cortisona , Adulto , Ritmo Circadiano , Estudios de Factibilidad , Femenino , Humanos , Hidrocortisona , Masculino , Reproducibilidad de los Resultados , Saliva
12.
Int J Behav Nutr Phys Act ; 18(1): 141, 2021 11 04.
Artículo en Inglés | MEDLINE | ID: mdl-34732219

RESUMEN

Physical activity (PA) and sedentary behaviour (SB) of pre-school aged children are associated with important health and developmental outcomes. Accurate measurement of these behaviours in young children is critical for research and practice in this area. The aim of this review was to examine the validity, reliability, and feasibility of measurement tools used to assess PA and SB of pre-school aged children.Searches of electronic databases, and manual searching, were conducted to identify articles that examined the measurement properties (validity, reliability or feasibility) of measurement tools used to examine PA and/or SB of pre-school aged children (3-7 years old). Following screening, data were extracted and risk of bias assessment completed on all included articles.A total of 69 articles, describing 75 individual studies were included. Studies assessed measurement tools for PA (n = 27), SB (n = 5), and both PA and SB (n = 43). Outcome measures of PA and SB differed between studies (e.g. moderate to vigorous activity, step count, posture allocation). Most studies examined the measurement properties of one measurement tool only (n = 65). Measurement tools examined included: calorimetry, direct observation, combined heart rate and accelerometry, heart rate monitors, accelerometers, pedometers, and proxy report (parent, carer or teacher reported) measures (questionnaires or diaries). Studies most frequently assessed the validity (criterion and convergent) (n = 65), face and content validity (n = 2), test-retest reliability (n = 10) and intra-instrument reliability (n = 1) of the measurement tools. Feasibility data was abstracted from 41 studies.Multiple measurement tools used to measure PA and SB in pre-school aged children showed some degree of validity, reliability and feasibility, but often for different purposes. Accelerometers, including the Actigraph (in particular GT3X versions), Actical, ActivPAL and Fitbit (Flex and Zip), and proxy reported measurement tools used in combination may be useful for a range of outcome measures, to measure intensity alongside contextual information.


Asunto(s)
Ejercicio Físico , Conducta Sedentaria , Acelerometría , Niño , Preescolar , Estudios de Factibilidad , Humanos , Reproducibilidad de los Resultados
13.
Artículo en Inglés | MEDLINE | ID: mdl-34770177

RESUMEN

eHealth could support cost-effective interdisciplinary primary care for patients with chronic musculoskeletal pain. This study aims to explore the feasibility of the eCoach-Pain, comprising a tool measuring pain complexity, diaries, pain education sessions, monitoring options, and chat function. Feasibility was evaluated (June-December 2020) by assessing learnability, usability, desirability, adherence to the application, and experiences from patients and general practitioners, practice nurses mental health, and physiotherapists. Six primary healthcare professionals (PHCPs) from two settings participated in the study and recruited 29 patients (72% female, median age 50.0 years (IQR = 24.0)). PHCPs participated in a focus group. Patient data was collected by evaluation questionnaires, individual interviews, and eCoach-Pain-use registration. Patients used the eCoach during the entire treatment phase (on average 107.0 days (IQR = 46.0); 23 patients completed the pain complexity tool and used the educational sessions, and 12 patients the chat function. Patients were satisfied with the eCoach-Pain (median grade 7.0 (IQR = 2.8) on a 0-10 scale) and made some recommendations for better fit with patient-specific complaints. According to PHCPs, the eCoach-Pain is of added value to their treatment, and patients also see treatment benefits. However, the implementation strategy is important for successful use of the eCoach-Pain. It is recommended to improve this strategy and involve a case-manager per patient.


Asunto(s)
Dolor Crónico , Dolor Musculoesquelético , Dolor Crónico/terapia , Estudios de Factibilidad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Dolor Musculoesquelético/terapia , Atención Primaria de Salud , Encuestas y Cuestionarios
14.
Artículo en Inglés | MEDLINE | ID: mdl-34770241

RESUMEN

The enhancement of physical activity is highly correlated with the conditions of the built environment. Walking is considered to be a fundamental daily physical activity, which requires an appropriate environment. Therefore, the barriers of the built environment should be identified and addressed. Barriers can act as external stimuli for pedestrians, so pedestrians may diversely respond to them. Based on this consideration, this study examines the feasibility of information-entropy-based behavioral analysis for the detection of environmental barriers. The physical responses of pedestrians were collected using an inertial measurement unit (IMU) sensor in a smartphone. After the acquired data were converted to behavioral probability distributions, the information entropy of each grid cell was calculated. The grid cells whereby the participants indicated that environmental barriers were present yielded relatively high information entropy values. The findings of this study will facilitate the design of more pedestrian-friendly environments and the development of diverse approaches that utilize citizens for monitoring the built environment.


Asunto(s)
Peatones , Entorno Construido , Entropía , Planificación Ambiental , Estudios de Factibilidad , Humanos , Caminata
15.
Sensors (Basel) ; 21(21)2021 Oct 26.
Artículo en Inglés | MEDLINE | ID: mdl-34770384

RESUMEN

A major cause of bone mass loss worldwide is osteoporosis. X-ray is considered to be the gold-standard technique to diagnose this disease. However, there is currently a need for an alternative modality due to the ionizing radiations used in X-rays. In this vein, we conducted a numerical study herein to investigate the feasibility of using microwave tomography (MWT) to detect bone density variations that are correlated to variations in the complex relative permittivity within the reconstructed images. This study was performed using an in-house finite-element method contrast source inversion algorithm (FEM-CSI). Three anatomically-realistic human leg models based on magnetic resonance imaging reconstructions were created. Each model represents a leg with a distinct fat layer thickness; thus, the three models are for legs with thin, medium, and thick fat layers. In addition to using conventional matching media in the numerical study, the use of commercially available and cheap ultrasound gel was evaluated prior to bone image analysis. The inversion algorithm successfully localized bones in the thin and medium fat scenarios. In addition, bone volume variations were found to be inversely proportional to their relative permittivity in the reconstructed images with the root mean square error as low as 2.54. The observations found in this study suggest MWT as a promising bone imaging modality owing to its safe and non-ionizing radiations used in imaging objects with high quality.


Asunto(s)
Pierna , Imágenes de Microonda , Densidad Ósea , Estudios de Factibilidad , Humanos , Procesamiento de Imagen Asistido por Computador
16.
Sensors (Basel) ; 21(21)2021 Oct 27.
Artículo en Inglés | MEDLINE | ID: mdl-34770447

RESUMEN

With the automotive industry moving towards automated driving, sensing is increasingly important in enabling technology. The virtual sensors allow data fusion from various vehicle sensors and provide a prediction for measurement that is hard or too expensive to measure in another way or in the case of demand on continuous detection. In this paper, virtual sensing is discussed for the case of vehicle suspension control, where information about the relative velocity of the unsprung mass for each vehicle corner is required. The corresponding goal can be identified as a regression task with multi-input sequence input. The hypothesis is that the state-of-art method of Bidirectional Long-Short Term Memory (BiLSTM) can solve it. In this paper, a virtual sensor has been proposed and developed by training a neural network model. The simulations have been performed using an experimentally validated full vehicle model in IPG Carmaker. Simulations provided the reference data which were used for Neural Network (NN) training. The extensive dataset covering 26 scenarios has been used to obtain training, validation and testing data. The Bayesian Search was used to select the best neural network structure using root mean square error as a metric. The best network is made of 167 BiLSTM, 256 fully connected hidden units and 4 output units. Error histograms and spectral analysis of the predicted signal compared to the reference signal are presented. The results demonstrate the good applicability of neural network-based virtual sensors to estimate vehicle unsprung mass relative velocity.


Asunto(s)
Conducción de Automóvil , Redes Neurales de la Computación , Teorema de Bayes , Estudios de Factibilidad , Memoria a Largo Plazo
17.
BMC Health Serv Res ; 21(1): 1225, 2021 Nov 12.
Artículo en Inglés | MEDLINE | ID: mdl-34772418

RESUMEN

BACKGROUND: Brief interventions have proven to be valuable instruments for the treatment and care of clients with diverse health needs, due to their potential to impact both the individual and the population. In this regard, the Brief Sexuality-Related Communication (BSC) is presented as a viable and effective alternative for addressing sexual and reproductive health problems, assessing risk behaviors and motivating clients to generate behavioral change. Since health providers are key actors in treatment and prevention, it is essential to know their perceptions about the BSC intervention, as well as its acceptability in different contexts, with diverse client populations. Thus, the following paper reflects the findings of the perceptions and experiences of health providers in Peru from the first phase of the Feasibility study of a BSC intervention to prevent STIs and unintended pregnancies. METHODS: This is the first phase of a multisite and multiphase study of the feasibility of a BSC intervention. We conducted twenty in-depth interviews (IDI) with health care providers (physicians, obstetricians, psychologists, nurses and peer counselors) recruited from three health care institutions in Peru: The Tahuantinsuyo Bajo Maternal and Child Center (CMI) and the San José Maternal and Child Center, both located in the capital city, Lima; and La Caleta Hospital located in Chimbote, northern coast of Peru. Participating health providers included those working at the HIV/STI Reference service and the family planning/reproductive health service. The IDI addressed three domains: 1) Acceptability of the BSC intervention; 2) Perceived willingness to implement the BSC intervention; and 3) Considerations for the Implementation of the BSC intervention. RESULTS: Health providers expressed high acceptance of the BSC intervention, considering it as a useful and effective instrument to address sexual and reproductive health problems with all clients; however, some providers had some concerns about the real impact of the intervention to achieve significant behavior change. On the other hand, health providers showed high willingness to learn and implement the BSC intervention, affirming their commitment to learn new techniques and strategies that could allow them to improve their knowledge and the quality of their care. Health care providers consider it necessary to take into account the barriers that arise in the implementation of the BSC intervention, such as the structural limitations to access, the providers' abilities to deliver the intervention effectively, and the participants' reception of the intervention. Finally, providers consider it essential to establish the BSC intervention in a normative framework that allows it to receive the support of the health departments and eventually enforces implementation. CONCLUSIONS: Health providers consider the BSC intervention as an interesting and exciting behavioral intervention to deal with the sexual and reproductive health issues existing in different populations, and seemed highly willing to adapt and implement it, hoping that it become beneficial to all client populations to prevent HIV/STIs and unintended pregnancies.


Asunto(s)
Infecciones por VIH , Enfermedades de Transmisión Sexual , Intervención en la Crisis (Psiquiatría) , Estudios de Factibilidad , Femenino , Infecciones por VIH/prevención & control , Personal de Salud , Humanos , Perú , Embarazo , Embarazo no Planeado , Enfermedades de Transmisión Sexual/prevención & control
18.
Trop Anim Health Prod ; 53(6): 545, 2021 Nov 15.
Artículo en Inglés | MEDLINE | ID: mdl-34779918

RESUMEN

For the past several decades, selective anthelmintic therapy (SAT) has been recommended in temperate climate countries for controlling gastrointestinal parasites in horses. However, the feasibility of this approach in tropical climates remains unknown, given the very different parasite transmission patterns and a larger representation of working equids. The aim of this study was to evaluate the bio-economic feasibility of SAT in horses kept under tropical conditions of Camagüey, Cuba. Fecal egg counts were determined from 794 adult horses and used for evaluating three different putative treatment thresholds; > 500 strongylid eggs per gram of feces (EPG); > 1000 EPG; and treatments yielding > 80% of the total herd egg output. These scenarios were evaluated under three treatment frequencies (every 2, 6, and 12 months). The bio-economic feasibility of these nine possible selective anthelmintic therapy scenarios was evaluated taking into account the cost of parasitological tests, and the mean cost of anthelmintic treatment in Camagüey. The majority (96.7%) of the samples tested were positive for strongyle eggs, with a mean of 1549 EPG. The percentage of horses exceeding the cut-off points at the nine scenarios varied between 40.1 and 93.8%. All owners surveyed used extra-label anthelmintic product in their horses on a routine basis. The economic analysis demonstrated that selective therapy generally was much more costly than deworming the entire herd without determining egg counts. However, we consider that the deworming every 6 months of the horses that expel 80% of the eggs in the herd allows a reduction of the treatment intensity without increasing costs, and it can be considered as a viable selective deworming scheme under similar conditions.


Asunto(s)
Antihelmínticos , Enfermedades de los Caballos , Infecciones Equinas por Strongyloidea , Animales , Antihelmínticos/uso terapéutico , Estudios de Factibilidad , Heces , Enfermedades de los Caballos/tratamiento farmacológico , Caballos , Óvulo , Recuento de Huevos de Parásitos/veterinaria , Infecciones Equinas por Strongyloidea/tratamiento farmacológico
19.
Am J Occup Ther ; 75(4)2021 Jul 01.
Artículo en Inglés | MEDLINE | ID: mdl-34780605

RESUMEN

IMPORTANCE: Societal stigma gravely impedes occupational justice for transgender and gender-nonconforming (TGNC) people, producing vast health disparities for this population. OBJECTIVE: To test the feasibility of an intervention to reduce stigma and improve the well-being of TGNC people. DESIGN: A parallel, mixed-methods design was used to test feasibility in the areas of acceptability, demand, and limited efficacy. SETTING: Community. PARTICIPANTS: Forty-two audience members and 5 TGNC interviewees. INTERVENTION: Virtual, narrative-informed play reading and moderated discussion about gender diversity and affirmative care. Outcomes and Measures: The valid and reliable Acceptance and Action Questionnaire-Stigma was used to assess stigma beliefs. An open-ended, qualitative question assessed TGNC interviewees' experiences. RESULTS: Recruitment and participant responses to the intervention indicated feasibility in the areas of acceptability, demand, and limited efficacy. However, future efforts at obtaining a diverse TGNC sample are needed. CONCLUSIONS AND RELEVANCE: The intervention decreased stigma beliefs in audience members and offered a positive experience for TGNC participants. Feasibility outcomes warrant future efficacy testing. What This Article Adds: This article adds an innovative intervention for promoting occupational justice to support the health and well-being of TGNC people. The community-based intervention facilitates change in societal attitudes and stigmatizing beliefs.


Asunto(s)
Personas Transgénero , Estudios de Factibilidad , Identidad de Género , Humanos , Justicia Social , Encuestas y Cuestionarios
20.
BMJ Open ; 11(11): e047829, 2021 11 09.
Artículo en Inglés | MEDLINE | ID: mdl-34753752

RESUMEN

OBJECTIVE: Despite available effective treatments for mental health disorders, few patients in need receive even the most basic care. Integrated telepsychiatry services may be a viable option to increase access to mental healthcare. The aim of this qualitative process evaluation embedded in a randomised controlled feasibility trial was to explore health providers' experiences with a mental healthcare model integrating mental health specialist video consultations (MHSVC) and primary care. METHODS: A qualitative process evaluation focusing on MHSVC in primary care was conducted. In 13 semistructured interviews, we assessed the experience of all mental health specialists, primary care physicians and medical assistants who participated in the trial. A thematic analysis, focusing on the implementation, mechanisms of impact and context, was applied to investigate the data. RESULTS: Considering (1) the implementation, participants evaluated the consultations as feasible, easy to use and time saving. Concerning (2) the mechanisms of impact, the consultations were regarded as effective for patients. Providers attributed the patients' improvements to two key aspects: the familiarity of the primary care practice and the fast access to specialist mental healthcare. Mental health specialists observed trustful therapeutic alliances emerging and described their experience as comparable to same-room care. However, compared with same-room care, specialists perceived the video consultations as more challenging and sometimes more exhausting due to the additional effort required for establishing therapeutic alliances. Regarding (3) the intervention's context, shorter travel distances for patients positively affected the implementation, while technical failures, that is, poor Internet connectivity, emerged as the main barrier. CONCLUSIONS: MHSVCs in primary care are feasible and successful in improving access to mental healthcare for patients. To optimise engagement and comfort of both patients and health providers, future work should focus on empirical determinants for establishing robust therapeutic alliances with patients receiving MHSVC (eg, leveraging non-verbal cues for therapeutic purposes). TRIAL REGISTRATION NUMBER: DRKS00015812; Results.


Asunto(s)
Psiquiatría , Telemedicina , Estudios de Factibilidad , Humanos , Salud Mental , Atención Primaria de Salud , Derivación y Consulta
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