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1.
Artículo en Inglés | MEDLINE | ID: mdl-33802062

RESUMEN

Although exposure to asbestos via various routes has been acknowledged, comprehensive exposure and risk assessment methods have not been developed at the national level. We conducted a study to reconstruct comprehensive past asbestos exposure estimations and to suggest a method to calculate the Excess Lifetime Cancer Risk (ELCR) of Koreans. The past occupational exposure reconstruction was conducted by rebuilding the previous general population job-exposure matrix (JEM). The para-occupational and household exposure estimation was based on the pooled analysis of data from other countries as well as Korea. The neighborhood exposure from occupational sources by distance was estimated by the exponential decay model. As a result, 141 JEM exposure groups across four periods including ~79, the 80s, 90s, 2000s with a ratio of 2.0:1.0:0.5:0.05 were reconstructed. The para-occupational and household exposures were 11% and 1% of the JEM respectively. The environmental exposure source concentration from outside occupational exposure was 2.5% of the inside concentration. The ratio of the concentration of environmental exposure source (C0) to distance d (Cd) was exp-kd  with a decay constant k of 6.834. The mean concentrations (f/cc) were 2.28 × 10-3 for outdoor, 4.65 × 10-5 for indoor, 1.95 × 10-2 for transportation activity, 4.44 × 10-2 for agricultural activity, and 4.68 × 10-2 for daily life activity in naturally occurring asbestos areas. Indoor and outdoor asbestos concentrations from living in a slate roof house were 1.73 × 10-6 and 2.70 × 10-8, respectively. For improved generalizability, validity, and applicability of the proposed method, further studies on each route with real assessments and experiments are required.


Asunto(s)
Asbestos , Neoplasias , Exposición Profesional , Asbestos/toxicidad , Exposición a Riesgos Ambientales , Humanos , Exposición Profesional/efectos adversos , Exposición Profesional/análisis , República de Corea/epidemiología , Medición de Riesgo
2.
Artículo en Chino | MEDLINE | ID: mdl-33910295

RESUMEN

Asbestos is harmful to human, and populations with occupational and environmental exposure to respirable asbestos fibers have higher risk of cancers like malignant mesothelioma and lung cancer. At present, patient with asbestos-induced malignant peritoneal mesothelioma and lung cancer is rare. In this study, we analyzed the clinical data of a case of asbestos-induced malignant peritoneal mesothelioma complicated with lung cancer to investigate the diagnosis and treatment of this disease.


Asunto(s)
Asbestos , Neoplasias Pulmonares , Mesotelioma , Exposición Profesional , Neoplasias Peritoneales , Asbestos/efectos adversos , Humanos , Exposición Profesional/efectos adversos
3.
J Occup Environ Hyg ; 18(4-5): 169-179, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33861938

RESUMEN

The coronavirus pandemic has taken a detrimental toll on the lives of individuals globally. In addition to the direct effect (e.g., being infected with the virus), this pandemic has negatively ravaged many industries, particularly food retail, food services, and hospitality. Given the novelty of the disease, the true impact of COVID-19 remains to be determined. Because of the nature of their work, and the characteristics of the workers, individuals in the food retail, food service, and hospitality industries are a group whose vulnerability is at its most fragile state during this pandemic. Through this qualitative study, we explored workers' perspectives on the impact of COVID-19 on their mental health and coping, including screening for post-traumatic stress disorder (PTSD) and alcohol use disorder symptoms. Twenty-seven individual interviews were conducted, audio-recorded, transcribed, and analyzed using qualitative content analysis. Four key themes emerged: being infected and infecting others, the unknown, isolation, and work and customer demands. Considering the many uncertainties of COVID-19, workers in these three industries were experiencing heightened levels of mental distress because of where they worked and the already existing disparities they faced on a daily basis before the pandemic started. Yet they remained hopeful for a better future. More studies are needed to fully understand the magnitude, short-term, and long-term effects of COVID-19. Based on this study's findings, programs are critically needed to promote positive coping behaviors among at-risk and distressed workers. Recommendations for employers, occupational health and safety professionals, and policy stakeholders to further support these service workers are discussed.


Asunto(s)
/psicología , Trastornos Mentales/epidemiología , Exposición Profesional/efectos adversos , Estrés Laboral , Adaptación Psicológica , Adulto , Alcoholismo/epidemiología , Comercio , Femenino , Servicios de Alimentación , Humanos , Masculino , Trastornos Mentales/etiología , Persona de Mediana Edad , Investigación Cualitativa , Trastornos por Estrés Postraumático/epidemiología , Encuestas y Cuestionarios , Estados Unidos
4.
Artículo en Inglés | MEDLINE | ID: mdl-33669843

RESUMEN

Increased mortality due to malignant mesothelioma has been demonstrated by several epidemiologic studies in the area around Broni (a small town in Lombardy, northern Italy), where a factory producing asbestos cement was active between 1932 and 1993. Until now, the inorganic fiber burden in lungs has not been investigated in this population. The aim of this study is to assess the lung fiber burden in 72 individuals with previous occupational and/or anthropogenic environmental exposure to asbestos during the activity of an important asbestos cement factory. Inorganic fiber lung burden was assessed in autoptic samples taken from individuals deceased from asbestos-related diseases using a scanning electron microscope equipped with an energy-dispersive spectrometer. Significant differences in the detected amount of asbestos were pointed out among the three types of exposure. In most lung samples taken from patients who died of mesothelioma, very little asbestos (or, in some cases, no fibers) was found. Such subjects showed a significantly lower median amount of asbestos as compared to asbestosis. Almost no chrysotile was detected in the examined samples. Overall, crocidolite was the most represented asbestos, followed by amosite, tremolite/actinolite asbestos, and anthophyllite asbestos. There were significant differences in the amount of crocidolite and amosite fibers according to the kind of exposure. Overall, these findings provide novel insights into the link between asbestos exposure and mesothelioma, as well as the different impacts of the various types of asbestos on human health in relation to their different biopersistences in the lung microenvironment.


Asunto(s)
Asbestos , Neoplasias Pulmonares , Mesotelioma , Exposición Profesional , Exposición a Riesgos Ambientales , Humanos , Italia/epidemiología , Pulmón , Neoplasias Pulmonares/epidemiología , Neoplasias Pulmonares/etiología , Mesotelioma/inducido químicamente , Mesotelioma/epidemiología , Exposición Profesional/efectos adversos , Microambiente Tumoral
5.
Radiat Res ; 195(3): 284-292, 2021 03 01.
Artículo en Inglés | MEDLINE | ID: mdl-33705554

RESUMEN

Workers of the Commissariat for Atomic Energy and Alternative Energy (CEA) may be potentially exposed to tritium over long periods. We aimed to assess the effect of tritium exposure on mortality in a cohort of employees followed by radiotoxicological monitoring. A total of 1,746 employees who worked for at least six months at one of three CEA centers were included between 1962 and 2011 (median follow-up 29.6 years). The cumulative dose of tritium was based on the quantification of tritium present from urinary excretion monitoring data from the beginning of occupational exposure to the end of such exposure or December 2011. Mortality was first compared to that in the French population using the standardized mortality ratio (SMR). Then, mortality risk ratios (RRs) per category of cumulative dose of tritium were estimated using categorical Poisson models adjusted for age at the onset of exposure, age, calendar period, sex, smoking, employment status, CEA center, and taking into account the number of person-years. The main causes of mortality were tumors (48%) and cardiovascular diseases (20%). The comparison of mortality within the cohort to that in the French population highlighted a lower rate for all-cause mortality and that due to cancer, related to the healthy worker effect bias. The regression model showed no effect of cumulative dose on all-cause mortality. The risk of death for most malignancies was positive, but not significant for the higher classes of doses relative to the reference class. The highest risk (not significant) was present for the class of higher doses for tumors of the larynx, trachea, bronchi and lung. The risk was significant for the higher doses for tumors of the pancreas and bladder (based on a limited number of cases: five and six deaths, respectively). Significantly more smokers died from tumors of the respiratory system than non-smokers, as expected. We were unable to show an effect of cumulative tritium dose due to the small size of the cohort and the low exposure level. However, our study underlines the need to continue following tritium-exposed workers and conducting multicenter studies.


Asunto(s)
Enfermedades Cardiovasculares/mortalidad , Enfermedades Profesionales/mortalidad , Exposición Profesional/efectos adversos , Tritio/efectos adversos , Adulto , Enfermedades Cardiovasculares/etiología , Enfermedades Cardiovasculares/patología , Causas de Muerte , Estudios de Cohortes , Estudios Epidemiológicos , Femenino , Francia , Humanos , Masculino , Persona de Mediana Edad , Enfermedades Profesionales/patología , Factores de Riesgo , Fumar/efectos adversos
6.
Environ Int ; 152: 106477, 2021 07.
Artículo en Inglés | MEDLINE | ID: mdl-33756429

RESUMEN

BACKGROUND: Multiple epidemiological studies have shown that exposure to single pesticide active ingredients or chemical groups is associated with adverse neurobehavioral outcomes in farmers. In agriculture, exposure to multiple pesticide active ingredients is the rule, rather than exception. Therefore, occupational studies on neurobehavioral effects of pesticides should account for potential co-exposure confounding. METHODS: We conducted a cross-sectional study of 288 Ugandan smallholder farmers between September and December 2017. We collected data on self-reported use of pesticide products during the 12 months prior to survey and estimated yearly exposure-intensity scores for 14 pesticide active ingredients using a semi-quantitative exposure algorithm. We administered 11 neurobehavioral tests to assess five neurobehavioral domains. We implemented a Bayesian Model-Averaging (BMA) approach to examine the association between exposure to multiple pesticides and neurobehavioral outcomes, while accounting for multiple testing. We applied two levels of inference to determine (1) which neurobehavioral outcomes were associated with overall pesticide exposure (marginal inclusion probability (MIP) for covariate-only models <0.5) and (2) which specific pesticide active ingredients were associated with these outcomes (MIP for models where active ingredient was included >0.5). RESULTS: Seventy-two percent of farmers reported use of pesticide products that contained at least one of 14 active ingredients, while the applicators used in median three different active ingredients (interquartile range (IQR) 4) in the 12 months prior to the study. The most widely used active ingredients were glyphosate (79%), cypermethrin (60%), and mancozeb (55%). We found that overall pesticide exposure was associated with impaired visual memory (Benton Visual Retention Test (BVRT)), language (semantic verbal fluency test), perceptual-motor function (Finger tapping test), and complex attention problems (Trail making A test and digit symbol test). However, when we looked at the associations for individual active ingredients, we only observed a positive association between glyphosate exposure and impaired visual memory (-0.103 [95% Bayesian Credible Interval (BCI)] [-0.24, 0] units in BVRT scores per interquartile range (IQR) increase in annual exposure to glyphosate, relative to a median [IQR] of 6 [3] units in BVRT across the entire study population). CONCLUSIONS: We found that overall pesticide exposure was associated with several neurobehavioral outcome variables. However, when we examined individual pesticide active ingredients, we observed predominantly null associations, except for a positive association between glyphosate exposure and impaired visual memory. Additional epidemiologic studies are needed to evaluate glyphosate's neurotoxicity, while accounting for co-pollutant confounding.


Asunto(s)
Exposición Profesional , Plaguicidas , Agricultura , Teorema de Bayes , Estudios Transversales , Agricultores , Humanos , Exposición Profesional/efectos adversos , Exposición Profesional/análisis , Plaguicidas/toxicidad , Uganda
7.
Ann Agric Environ Med ; 28(1): 27-43, 2021 Mar 18.
Artículo en Inglés | MEDLINE | ID: mdl-33775065

RESUMEN

INTRODUCTION AND OBJECTIVE: The course of COVID-19 caused by the SARS-CoV-2 may be aggravated by bioaerosols containing other viruses, bacteria, and fungi, occurring mainly in the occupational environment. Hence, the diagnostics and treatment of COVID-19 should address such a possibility in the anamnesis, treatment and final recommendations for avoiding of adverse exposure. ABBREVIATED DESCRIPTION OF THE STATE OF KNOWLEDGE: As SARS-CoV-2 attacks primarily the respiratory system and the severe manifestation of COVID-19 is interstitial pneumonia, diagnostics should include the following clinical and laboratory examinations: chest X-ray; high resolution computed tomography (HRCT); pulmonary function tests; arterial-blood gas test; genetic tests for the presence of SARS-CoV-2, in the future with the use of highly specific and sensitive nano-based biosensors; tests for the presence of specific immunity against the antigens of microorganisms causing other infectious or allergic pulmonary diseases (in the case of anamnestic indications). Because an universally accepted treatment for COVID-19 does not exist, the hitherto prescribed antiviral and immune-modulating drugs should be used be with caution. In many cases, a better alternative could be a safe supportive therapy, such as supplementation of the diet with probiotics, prebiotics, vitamins and microelements. SUMMARY: The most important preventive measures against COVID-19 should include: vaccination; the use of filter or surgical masks; disinfection and sterilization; maintaining of well-functioning ventilation and air conditioning systems; reduction of the community air pollution which has been identified as an important factor increasing the COVID-19 severity. In the choice of preventive measures, the above should be considered for their potential efficacy against other bioaerosols as potential disease-aggravating agents.


Asunto(s)
/diagnóstico , /terapia , Aerosoles/efectos adversos , Humanos , Enfermedades Profesionales/complicaciones , Enfermedades Profesionales/prevención & control , Exposición Profesional/efectos adversos , Exposición Profesional/prevención & control , Enfermedades Respiratorias/complicaciones , /aislamiento & purificación
8.
Dtsch Arztebl Int ; 118(4): 41-48, 2021 Jan 29.
Artículo en Inglés | MEDLINE | ID: mdl-33759743

RESUMEN

BACKGROUND: From 1946 to 1990, more than 400 000 people were employed by Wismut AG, a Soviet/Soviet-German corporation (German abbreviation: SAG/ SDAG), in the East German states of Saxony and Thuringia. In the early years in particular, employees were exposed to large amounts of radon and respirable crystalline silica. METHODS: In a cohort of 35 204 former underground employees of Wismut AG, mortality was analyzed in comparison to the general male population of East Germany, and the pertaining standardized mortality ratios (SMRs) were calculated. RESULTS: 18 510 persons in the study cohort died in the follow-up period 1960-2013. Mortality from lung cancer was 2.36 higher in the study cohort than in the general population (95% confidence interval, [2.28; 2.45]); the associated SMRs rose markedly with increasing radon exposure. Mortality from silicosis and other types of pneumoconiosis was elevated by a factor of 22.62 [21.20; 24.11], and the associated SMRs rose exponentially with increasing exposure to respirable crystalline silica. Mortality from both of these causes was still markedly elevated more than 20 years after Wismut AG had ceased its activities. Mortality from a wide range of other diseases was elevated as well, with the following SMRs: stomach cancer, 1.28 [1.17; 1.40]; liver cancer, 1.34 [1.15; 1.55]; all tumors other than lung cancer, 1.06 [1.02; 1.09]; infections, 1.18 [1.01; 1.38]; cerebrovascular diseases, 1.33 [1.26; 1.41]; and influenza/pneumonia, 1.13 [1.01; 1.27]. Mortality from a small number of other causes was found to be markedly lowered in the study cohort (mental illness, renal diseases, and nervous system diseases). The role of occupational risk factors, lifestyle differences and other reasons for the latter results is unclear. CONCLUSION: Underground miners employed by Wismut AG displayed marked excess mortality due to silicosis/other pneumoconiosis and lung cancer. The contribution of individual occupational risk factors for these and other causes of death with increased SMR are being further investigated in analyses within the study cohort.


Asunto(s)
Neoplasias Pulmonares , Enfermedades Profesionales , Exposición Profesional , Radón , Silicosis , Uranio , Causas de Muerte , Estudios de Cohortes , Humanos , Masculino , Exposición Profesional/efectos adversos
11.
Workplace Health Saf ; 69(4): 154-160, 2021 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-33787420

RESUMEN

BACKGROUND: Planning occupational health and wellness services and support directed toward low-wage, essential workers in the COVID-19 pandemic has posed a number of challenges across work settings. This article explores the concerns and needs of low-wage essential workers as understood by experts in the field. METHODS: Leading experts in the areas of occupational health and safety, risk management, insurance, and professional education/training were identified and invited to participate in a Round Table discussion. Questions posed to experts were based on literature that addressed COVID-19, essential workers, low-wage workers, infection transmission, education/training, and social justice. FINDINGS: Experts agreed that special considerations must be in place to address the concerns and needs of the low-wage essential worker. These special considerations should address not only the worker's occupational experience but their family and home environment, fears and anxieties, and the economic impact of the COVID-19 restrictions and requirements. CONCLUSION/APPLICATION TO PRACTICE: The occupational health professional is a key resource to employers charged with addressing the concerns and needs of low-wage, essential workers during the COVID-19 pandemic.


Asunto(s)
Renta/estadística & datos numéricos , Exposición Profesional/efectos adversos , Recursos Humanos/estadística & datos numéricos , /etiología , Humanos , Exposición Profesional/estadística & datos numéricos , Pandemias/prevención & control , Pandemias/estadística & datos numéricos
12.
Artículo en Inglés | MEDLINE | ID: mdl-33652998

RESUMEN

Work-related asthma (WRA) is a very frequent condition in the occupational setting, and refers either to asthma induced (occupational asthma, OA) or worsened (work-exacerbated asthma, WEA) by exposure to allergens (or other sensitizing agents) or to irritant agents at work. Diagnosis of WRA is frequently missed and should take into account clinical features and objective evaluation of lung function. The aim of this overview on pulmonary function testing in the field of WRA is to summarize the different available tests that should be considered in order to accurately diagnose WRA. When WRA is suspected, initial assessment should be carried out with spirometry and bronchodilator responsiveness testing coupled with first-step bronchial provocation testing to assess non-specific bronchial hyper-responsiveness (NSBHR). Further investigations should then refer to specialists with specific functional respiratory tests aiming to consolidate WRA diagnosis and helping to differentiate OA from WEA. Serial peak expiratory flow (PEF) with calculation of the occupation asthma system (OASYS) score as well as serial NSBHR challenge during the working period compared to the off work period are highly informative in the management of WRA. Finally, specific inhalation challenge (SIC) is considered as the reference standard and represents the best way to confirm the specific cause of WRA. Overall, clinicians should be aware that all pulmonary function tests should be standardized in accordance with current guidelines.


Asunto(s)
Asma Ocupacional , Enfermedades Profesionales , Exposición Profesional , Administración por Inhalación , Asma Ocupacional/diagnóstico , Pruebas de Provocación Bronquial , Humanos , Enfermedades Profesionales/diagnóstico , Exposición Profesional/efectos adversos , Espirometría
13.
FP Essent ; 502: 11-17, 2021 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-33683849

RESUMEN

Occupational lung diseases are caused by workplace inhalation of chemicals, dusts, or fumes. They include asbestosis, silicosis, coal workers' pneumoconiosis (CWP), and occupational asthma. These diseases have nonspecific respiratory symptoms and are only identified if an occupational history is taken. Asbestosis typically is diagnosed 20 to 30 years after peak exposure, often when pleural plaques are noted on chest x-ray (CXR). Asbestosis is associated with an increased cancer risk, which is higher in smokers. Silicosis results from exposure to silica dust from sand, stone, and quartz. It is a fibrotic lung disease with acute, chronic, or accelerated presentations; CXR findings show interstitial fibrosis or nodular opacities. Silicosis increases risk of mycobacterial and fungal infections. In CWP, patients may present with mild symptoms and CXR findings showing small fibrous nodules; progressive massive fibrosis may develop, and there is a risk of mycobacterial and fungal infections. Occupational asthma (OA) can occur de novo from inhaling sensitizers that induce immunoglobulin E-mediated airway reactions, or from inhaling irritants such as smoke, dust, and fumes. OA also can be due to sensitizers/irritants aggravating preexisting asthma. There are no cures for these occupational lung diseases, so prevention, including elimination/control of workplace exposures, and early diagnosis are key.


Asunto(s)
Asbestosis , Minas de Carbón , Enfermedades Profesionales , Exposición Profesional , Neumoconiosis , Silicosis , Humanos , Enfermedades Profesionales/diagnóstico , Enfermedades Profesionales/epidemiología , Exposición Profesional/efectos adversos , Neumoconiosis/diagnóstico por imagen , Neumoconiosis/epidemiología , Silicosis/diagnóstico por imagen , Silicosis/epidemiología
14.
Artículo en Chino | MEDLINE | ID: mdl-33691377

RESUMEN

Artificial quartz stone is a new type of decorative building material, there are serious dust exposure hazards during the production and processing. Due to the lack of effective health protection for practitioners, silicosis caused by artificial quartz stone dust has been widely reported worldwide in recent years, which seriously affect the health of practitioners. This article summarizes the use status of artificial quartz stone, the exposure of practitioners and the lung tissue damage caused by dust, analyzes its pathogenic characteristics, and provides a basis for protecting the occupational population and improving occupational health.


Asunto(s)
Exposición Profesional , Silicosis , Polvo , Humanos , Pulmón , Exposición Profesional/efectos adversos , Exposición Profesional/análisis , Cuarzo/toxicidad , Dióxido de Silicio , Silicosis/etiología
16.
Pneumologie ; 75(3): 201-205, 2021 Mar.
Artículo en Alemán | MEDLINE | ID: mdl-33728629

RESUMEN

The S2k guideline "Diagnostics and assessment of occupational asbestos-related diseases" was updated in November 2020. This article summarizes the most important changes. There is a new reference to the risk of potentially high exposures to asbestos fibers when renovating plaster, fillers and adhesives containing asbestos.Biomarkers such as mesothelin and calretinin should currently only be used in the context of research. The "asbestos airways disease", which can only be diagnosed histologically, is included in the guideline as an early form of asbestosis. Since the UIP pattern is not characteristic of asbestosis, computed tomography cases with UIP patterns alone cannot be assigned reliably to asbestosis without the simultaneous detection of pleural plaques. With regard to the evaluation of the functional damage, attention is drawn to the importance of flow volume curve, whole-body plethysmography, diffusion capacity and exercise testing. If available, the reference values ​​according to GLI are the basis of the assessment. The guideline contains specific recommendations on prevention, medical treatment and, for the first time, on the importance of outpatient rehabilitation and training therapy. There are also references to the assessment of the new occupational disease ovarian cancer after occupational exposure to asbestos.


Asunto(s)
Asbestos , Asbestosis , Enfermedades Profesionales , Exposición Profesional , Enfermedades Pleurales , Asbestos/toxicidad , Asbestosis/diagnóstico , Humanos , Enfermedades Profesionales/diagnóstico , Exposición Profesional/efectos adversos
17.
Klin Lab Diagn ; 66(2): 99-103, 2021 Mar 13.
Artículo en Inglés | MEDLINE | ID: mdl-33734643

RESUMEN

At the present stage of development of society, the issues of preserving and strengthening the most important productive force that determine the economic development and national security of the country remain relevant. Metallurgy is one of the basic industries in Russia, which forms up to 20% of GDP. This study assesses the condition of the oral mucosa in workers in the industry. To evaluate the formation of micronuclei in buccal cells as an early biomarker of health disorders as a result of occupational exposure to production factors of a metallurgical plant. Hygienic and clinical laboratory tests were carried out for workers of the metallurgical plant of the Republic of Bashkortostan. Cytological studies of the buccal epithelium were performed. Statistical processing of the results was carried out using the applied programs IBM, SPSS, Statistics, Microsoft Excel. The general assessment of working conditions in accordance with the criteria of R.2.2.2006-05 for workers of the metallurgical plant was established as 3.2-3.3. Analysis of the buccal epithelium revealed the occurrence of cells with cytogenetic disorders in the workers of the main group. Cells with atypical nuclei were identified in workers with a duration of contact with unfavorable factors of production for more than ten years. Signs of nuclear destruction were revealed, characterizing an increase in apoptotic activity in workers with prolonged contact times. Studies have shown that with more than 10 years of work experience, proliferation processes prevail over differentiation processes. The results obtained can be used as diagnostic methods that expand the prospects for identifying pre-pathological and pathological conditions.


Asunto(s)
Mucosa Bucal , Exposición Profesional , Baskiria , Análisis Citogenético , Epitelio , Humanos , Metalurgia , Exposición Profesional/efectos adversos , Federación de Rusia
18.
Arch. prev. riesgos labor. (Ed. impr.) ; 24(1): 47-61, ene.-mar. 2021. tab, graf
Artículo en Español | IBECS | ID: ibc-197120

RESUMEN

OBJETIVO: Revisar la literatura científica relacionada con los efectos de la exposición ocupacional a factores de riesgo para neoplasias cutáneas en trabajadores del sector pesquero. MÉTODO: Análisis crítico de los trabajos recuperados mediante revisión sistemática en MEDLINE (PubMed), EMBASE, The Cochrane Library, Scopus, Web of Science y Literatura Latinoamericana y del Caribe en Ciencias de la Salud (LILACS). Se evaluó la calidad de los artículos seleccionados mediante el cuestionario STROBE. RESULTADOS: Al atribuir los criterios de inclusión y exclusión a la búsqueda, se aceptaron 11 estudios para su revisión. En 7 de ellos, se obtuvo una asociación estadísticamente significativa entre neoplasia cutánea y exposición ocupacional. CONCLUSIONES: Se observa una relación entre lesiones malignas y exposición a radiación ultravioleta en el ámbito laboral, no obstante, la existencia de posibles sesgos hace que los resultados deban de tomarse con precaución


OBJECTIVE: To review the scientific literature related to the effects of occupational exposure to risk factors for skin neoplasms in fishery workers. METHOD: Critical analysis of the papers recovered through systematic review from en MEDLINE (PubMed), EMBASE, The Cochrane Library, Scopus, Web of Science y Literatura Latinoamericana y del Caribe en Ciencias de la Salud (LILACS). STOROBE guidelines were followed to evaluate their quality. RESULTS: After attributing inclusion and exclusion criteria to the search, 11 articles were accepted for review and critical analysis. In 7 of them, a statistically significant association was obtained between skin neoplasia and occupational exposure in fishermen. CONCLUSIONS: Despite having found studies that were significant in terms of the relationship of malignant lesions and exposure to ultraviolet radiation in the workplace, some of them did not control possible biases, therefore the results should be taken with caution


Asunto(s)
Humanos , Masculino , Femenino , Rayos Ultravioleta/efectos adversos , Neoplasias Cutáneas/etiología , Exposición Profesional/efectos adversos , Explotaciones Pesqueras , Factores de Riesgo , Estudios Transversales , Lugar de Trabajo , Industria Pesquera
19.
Artículo en Inglés | MEDLINE | ID: mdl-33546187

RESUMEN

Three cohorts including the Fire Department of the City of New York (FDNY), the World Trade Center Health Registry (WTCHR), and the General Responder Cohort (GRC), each funded by the World Trade Center Health Program have reported associations between WTC-exposures and cancer. Results have generally been consistent with effect estimates for excess incidence for all cancers ranging from 6 to 14% above background rates. Pooling would increase sample size and de-duplicate cases between the cohorts. However, pooling required time consuming steps: obtaining Institutional Review Board (IRB) approvals and legal agreements from entities involved; establishing an honest broker for managing the data; de-duplicating the pooled cohort files; applying to State Cancer Registries (SCRs) for matched cancer cases; and finalizing analysis data files. Obtaining SCR data use agreements ranged from 6.5 to 114.5 weeks with six states requiring >20 weeks. Records from FDNY (n = 16,221), WTCHR (n = 29,372), and GRC (n = 33,427) were combined de-duplicated resulting in 69,102 unique individuals. Overall, 7894 cancer tumors were matched to the pooled cohort, increasing the number cancers by as much as 58% compared to previous analyses. Pooling resulted in a coherent resource for future research for studies on rare cancers and mortality, with more representative of occupations and WTC- exposure.


Asunto(s)
Neoplasias , Exposición Profesional , Ataques Terroristas del 11 de Septiembre , Humanos , Incidencia , Neoplasias/epidemiología , New York/epidemiología , Ciudad de Nueva York/epidemiología , Exposición Profesional/efectos adversos , Trabajo de Rescate
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