Remembering Edmund Klein: the Father of Immunotherapy

Edmund Klein’s seminal research in oncology transformed medicine. He would now be 100 years old. This extraordinary physician–scientist has been dubbed the Father of Immunotherapy and was honored with the highest American recognition in medicine, the Lasker Award, often a prelude to the Nobel Prize (AU)

[Historical review of schistosomiasis prevention and treatment in southern Anhui from 1950 to 1970].

From 1950 to 1970, under the leadership of the central government, workstations for the prevention and control of schistosomiasis were established in the southern Anhui region. In terms of controlling the source of the disease, light and severe epidemic areas were scientifically divided. By opening new ditches to replace old ones, changing paddy fields to dry fields, and using traditional Chinese medicine and Western medicine to prevent the intermediate host of schistosomiasis, oncomelania from surviving. By managing the feces from human and animals and controlling the water source, the transmission route of schistosome eggs has been effectively cut off. At the same time, the education of hygiene awareness among susceptible populations were strengthened. In terms of diagnosis, modern physical and biochemical detection were used to improve the accuracy of diagnosis. In terms of treatment, by combining traditional Chinese medicine and Western medicine, together with the splenectomy, the cure rates were improved. In the process of preventing and controlling schistosomiasis, the governments of Anhui Province and the southern region of Anhui Province achieved good results, providing useful reference for the prevention and control of other diseases.

Forgotten Pediatrics: 8 Disturbing Windows on the Past.

The 75 years since Pediatrics was first published has witnessed an explosion of the scientific knowledge base informing child health. Yet, the path leading to the present has not been linear. We examine several articles that illustrate some of the unexpected twists and turns that have characterized our specialty's history. We hope that it will provide a reminder of the ever-changing nature of scientific knowledge and the need to continually re-evaluate how our own cultural assumptions shape medical practice.

Commentary: Visual Cultures, Publication Technologies, and Legitimation in the Life Sciences.

This paper comments on five articles in the special issue "Circulating Images in the Life Sciences." It sees the papers as unified by two themes. The first is their attention to the processes of legitimation. The second is the embedding of the images in textual cultures, which changed over time from the mid-nineteenth century to the very recent past, most notably with the recent advent of digital culture.

Michael Przybylski (1948-2023) Devoted Half a Century to Mass Spectrometry.

Michael Przybylski (1948-2023) was a Polymer Chemist by training and devoted nearly his entire scientific life, almost 50 years, to mass spectrometry and its biomedical applications. After earning his PhD in Chemistry, there followed a Postdoc stay at the National Cancer Institute, Bethesda, MD, USA, and his habilitation at the University of Mainz, Germany. Soon thereafter, Michael Przybylski took the Chair for Analytical Chemistry at the University of Konstanz, Germany, where he served as Director of the Analytical Chemistry and Biopolymer Structure Analysis Laboratory. As Emeritus Michael Przybylski moved the Steinbeis Centre for Biopolymer Analytics and Biomedical Mass Spectrometry to Rüsselsheim, Germany. Michael Przybylski's research was from the beginning interdisciplinary-oriented and in many ways groundbreaking: leading to over 400 scientific papers published in internationally renowned journals and to about 25 patents. Michael Przybylski gave approximately 150 invited lectures and was awarded several scientific prizes. In recognition of his outstanding achievements and fruitful collaboration, he received the Doctorate of honor from the "Alexandru Ioan Cuza" University of Iasi, Romania. Michael Przybylski was the Director of the by him founded "Biopolymer Analytics and Biomedical Mass Spectrometry" research center until his sudden and unexpected death.

Two Phases in the Intervention of Melanie Klein.

In 1930, Melanie Klein published an article presenting the case of Dick. Within the framework of the psychoanalytic technique adapted to the clinical treatment of autism, this article contributes elements to a question posed by many psychoanalysts: why did Klein's interventions affect Dick? To that end, Klein's first intervention is divided into two phases: a first naming phase, consented to by Dick; and a second interpretation phase, triggering detachment from the object, anxiety, and stereotypy. The proposal is to understand the emergence of anxiety in the relationship that the second-phase interpretation has with the first phase of naming.

New archival digital exhibit.

Innovations in Language, Emotion, and Empathy Research is a digital exhibit which celebrates the forgotten contributions to psychology by Prof. Vincent V. Herr, S. J. (1901-1970) and his colleagues in the mid-20th century. It draws on the substantial unpublished material in the Herr Papers at the Loyola University Chicago Archives and Special Collections. The online exhibition showcases over 40 archival documents, images, and photographs. These are elaborated with detailed text presenting Herr's research achievements and impactful collaborations. During his time at Loyola University Chicago, Herr pursued a range of interrelated projects using innovative assessment approaches to measure linguistic, emotional, and social aspects of healthy and disordered mental states. He was adept in experimental techniques which he applied to questions in psychiatry and social psychology. Herr investigated individual differences in emotionality and empathy through original tasks and instrumental measures. He collaborated with colleagues at Harvard and Yeshiva Universities on the religion and mental health project in the 1950s and 1960s supported by the National Institute of Mental Health and became an advisor to Vatican II in 1965. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

Reconstruction of Wilhelm Wundt's last residence in Saxony and the search for subsequent use as a research institute, fellowship house, or museum of psychotechnics.

The German physiologist Wilhelm Wundt (1832-1920) is now recognized worldwide as the founding figure of academic psychology. He founded the first Institute for Experimental Psychology in Leipzig in 1879 and gained recognition during his lifetime. The scientist's last home in the small village of Großbothen in East Germany, about 100 miles (160 km) south of Berlin, was left to decay after German reunification in 1989/1990. Wundt's other homes in Leipzig were destroyed during World War II. During the GDR period, when the house was owned by the public sector, an inscription in honor of Wundt was added. It then stood empty for many years and fell into disrepair. In June 2016, an association was founded at Schloss Altranstädt near Leipzig with the aim of acquiring the rights to use the Wilhelm Wundt House. Thanks to their efforts, the house has now been entrusted to a conservationist as of 2018. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

Health Conditions in Tehran's Girl Schools from 1927 to 1934: A Brief Survey.

A new model of relations emerged in schools after the establishment of new educational centers in Iran in the mid-Qajar era. The cultural authorities of the time were particularly interested in school health, which was adopted as a principle from the European, particularly French, school systems. During the period 1925 to 1941, with special attention to the new Western models of education, school health changed more and more. This study provides a descriptive-analytical report on state health policies in girl schools in Tehran, Iran, from 1927 to 1934, based on health records available at the National Archives of Iran. The findings reveal that since the mid-first Pahlavi era, officials from the Ministry of Science became increasingly involved in the issue of health, which resulted in institutionalization of health and medical examination of students, establishment of the School Health Office, publication of theoretical health discussions in magazines, and teaching of health principles to students, thereby improving the level of health in Tehran schools during the study period. The study aims to provide Iranian physicians and health policymakers with a review of this historical experience.

Truman Capote as a Poet.

Truman Capote (1924-1984) was a fascinating, entertaining, and much ballyhooed American character who came of age in the mid-Twentieth Century. Some would say he led a tragic life. Often described as a notable novelist, he was more generally a polymath dabbling in nonfiction between his parties. He also was a screenwriter, playwright, actor, and short-story writer. His literary classics include the novella Breakfast at Tiffany's (1958, movie 1961) and true crime nonfiction "novel" (as Capote described it) In Cold Blood (1965, movie 1967). These two efforts became his most famous. But what about his poetry? Was this one of his creative passions?

[To the 90th anniversary of the department of pathological anatomy with a course of forensic medicine named after professor D.D.Lokhov of Saint Petersburg State Pediatric Medical University]. / K 90-letiyu kafedry patologicheskoi anatomii s kursom sudebnoi meditsiny im. professora D.D. Lokhova Sankt-Peterburgskogo gosudarstvennogo pediatricheskogo meditsinskogo universiteta.

The article is devoted to the history of Professor D.D. Lokhov Department of Pathological Anatomy with a course of forensic medicine of the St. Petersburg State Pediatric Medical University of the Ministry of Health of Russia, founded by one of founders of the national pathological anatomy of childhood and adolescence, Professor D.D. Lokhov, whose name has been awarded to the Department since 2022. The updated advances of the Department in research, teaching and diagnostic activity are presented.

[100th anniversary of the birth of Alexander Vsevolodovich Zinserling]. / 100 let so dnya rozhdeniya Aleksandra Vsevolodovicha Tsinzerlinga.

In December 2022, the Department of Pathological Anatomy of the St. Petersburg State Pediatric Medical University solemnly celebrated its 90th anniversary. At the meeting of the city scientific society of pathologists, dedicated to this event, the staff of the department, fellow professors, members of the society, as well as clinicians and invited guests, recalled the brilliant scientists-pathologists who led the specified department in different years. One of these scientists, who headed the department in 1965-1992, was a well-known scientist, corresponding member of the Russian Academy of Medical Sciences, prof. A.V. Zinzerling (1923-1995).

[History of congresses of surgeons in Russia (1900-2022)]. / Istoriya s"ezdov khirurgov Rossii (1900­2022).

The authors describe a history of surgical congresses in the Russian Empire, the USSR and the Russian Federation from the I Congress of Russian Surgeons held on December 28-30, 1900 in Moscow in the building of the Moscow Meeting of Doctors to the XLVIII (XIV) Congress of Surgeons of Russia held on November 25-27, 2022 in Moscow in the hotel «Cosmos¼. The time and place of congresses, as well as chairmen are named. The main issues are listed. Scientific issues of congresses between 1900 and 1986 are summarized in tables. The authors present a brief history of Russian surgical societies including the current Russian Society of Surgeons. Surgical forums of the 21st century are considered in detail (Congresses of Surgeons of Russia, National Surgical Congresses, All-Russian Surgical Forums). Finally, the authors came to conclusion that 55 surgical forums have been held in Russia for more than 120 years. Surgeons presented all aspects of surgery in Russia. Their issues are essentially the history of Russian surgery, and their works are sources for analysis of the past and present of Russian surgery.

Franz Volhard: 150th Birth Anniversary of a Father of Nephrology and Hypertension.

Franz Volhard (May 2, 1872, to May 24, 1950) was a German clinician and researcher who made outstanding contributions to the field of nephrology and hyper-tension. His studies led to important developments in knowledge about the pathophysiology of the kidney and its relationship to cardiovascular disease. He contributed to a better understanding of the mechanisms underlying renovascular hypertension by explaining the crucial relationship between the decrease in renal blood flow and the increase in blood pressure. He also introduced a precise classification of the different types of hypertension and the associated renal involvement. In collaboration with Karl Theodor Fahr (1877-1945), he developed a new classification of Bright's disease (nephritis), which was published in the book Die Brightsche Nierenkrankheit. Klinik, Pathologie und Atlas, and revolutionized the concepts behind the mechanisms of glomerulonephritis. During his distinguished career, Volhard headed departments of internal medicine at the Luisenhospital in Dortmund (1905-1910) and in Mannheim (1910-1918). In 1918, he became chairman of the Department of Internal Medicine at the University of Halle, his alma mater, until 1928, the same year he became chairman of the Department of Internal Medicine at the University of Frankfurt until 1938. Volhard continued his successful career until 1950, when he died of complications from a car accident. The worldwide medical com-munity greatly appreciated Franz Volhard's scientific contribution. The International Society of Hypertension posthumously presented him with the "Franz Volhard Award." The aim of this article is to commemorate the importance of this giant of nephrology 150 years after his birth.