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Rev Paul Pediatr ; 39: e2020217, 2021.
Artículo en Portugués, Inglés | MEDLINE | ID: mdl-32876096


OBJECTIVE: To analyze the current scientific literature to document, in an integrative review, the main findings that correlate Kawasaki disease (KD) to COVID-19. DATA SOURCES: The search was carried out in June 2020 in the following databases: Biblioteca Virtual em Saúde (BVS), periódico da CAPES and U.S National Library of Medicine (PubMed). The combination of descriptors used was [(COVID-19 OR SARS-CoV-2) AND (Kawasaki disease)], and the inclusion criteria stipulated were studies published from January 2019 to June 2020, without restriction of language or location, and available online in full. News, editorials, comments, and letters, as well as duplicates and articles that did not answer the guiding question were excluded. DATA SYNTHESIS: A total of 97 articles were identified, of which seven comprised this review. The association of KD to the new coronavirus appears to trigger a severe clinical condition of vasculitis. Different from the usual, in this inflammatory syndrome, patients are older, and prevalence is higher in children from African or Caribbean ancestry; clinical and laboratory manifestations are also atypical, with a predominance of abdominal complaints and exaggerated elevation of inflammatory markers. In addition, there was a greater report of rare complications and greater resistance to the recommended treatment for KD. CONCLUSIONS: Pediatric COVID-19 and its potential association to severe KD, still unfamiliar to health professionals, reinforces the importance of testing patients with vasculitis for the new coronavirus and the need to wage high surveillance and preparation of the health system during the current pandemic.

Infecciones por Coronavirus , Síndrome Mucocutáneo Linfonodular , Pandemias , Neumonía Viral , Síndrome de Respuesta Inflamatoria Sistémica/virología , Betacoronavirus/aislamiento & purificación , Niño , Infecciones por Coronavirus/epidemiología , Infecciones por Coronavirus/inmunología , Infecciones por Coronavirus/fisiopatología , Manejo de la Enfermedad , Humanos , Síndrome Mucocutáneo Linfonodular/epidemiología , Síndrome Mucocutáneo Linfonodular/terapia , Síndrome Mucocutáneo Linfonodular/virología , Neumonía Viral/epidemiología , Neumonía Viral/inmunología , Neumonía Viral/fisiopatología
Ann Lab Med ; 41(2): 129-138, 2021 Mar 01.
Artículo en Inglés | MEDLINE | ID: mdl-33063674


Since its first report in December 2019, coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly emerged as a pandemic affecting nearly all countries worldwide. As the COVID-19 pandemic progresses, the need to identify genetic risk factors for susceptibility to this serious illness has emerged. Host genetic factors, along with other risk factors may help determine susceptibility to respiratory tract infections. It is hypothesized that the ACE2 gene, encoding angiotensin-converting enzyme 2 (ACE2), is a genetic risk factor for SARS-CoV-2 infection and is required by the virus to enter cells. Together with ACE2, transmembrane protease serine 2 (TMPRSS2) and dipeptidyl peptidase-4 (DPP4) also play an important role in disease severity. Evaluating the role of genetic variants in determining the direction of respiratory infections will help identify potential drug target candidates for further study in COVID-19 patients. We have summarized the latest reports demonstrating that ACE2 variants, their expression, and epigenetic factors may influence an individual's susceptibility to SARS-CoV-2 infection and disease outcome.

Betacoronavirus/genética , Infecciones por Coronavirus/patología , Variación Genética , Neumonía Viral/patología , Betacoronavirus/aislamiento & purificación , Infecciones por Coronavirus/virología , Dipeptidil Peptidasa 4/genética , Dipeptidil Peptidasa 4/metabolismo , Susceptibilidad a Enfermedades , Expresión Génica , Humanos , Pandemias , Peptidil-Dipeptidasa A/química , Peptidil-Dipeptidasa A/genética , Peptidil-Dipeptidasa A/metabolismo , Neumonía Viral/virología , Serina Endopeptidasas/genética , Serina Endopeptidasas/metabolismo , Índice de Severidad de la Enfermedad
Ann Lab Med ; 41(2): 225-229, 2021 Mar 01.
Artículo en Inglés | MEDLINE | ID: mdl-33063685


In response to the ongoing coronavirus disease 2019 (COVID-19) pandemic, an online laboratory surveillance system was established to monitor severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) real-time reverse transcription-PCR (rRT-PCR) testing capacities and results. SARS-CoV-2 rRT-PCR testing data were collected from 97 clinical laboratories, including 84 medical institutions and 13 independent clinical laboratories in Korea. We assessed the testing capacities to utilize SARS-CoV-2 rRT-PCR based on surveillance data obtained from February 7th to June 4th, 2020 and evaluated positive result characteristics according to the reagents used and sample types. A total of 1,890,319 SARS-CoV-2 rRT-PCR testing were performed, 2.3% of which were positive. Strong correlations were observed between the envelope (E) gene and RNA-dependent RNA polymerase (RdRp)/nucleocapsid (N) genes threshold cycle (Ct) values for each reagent. No statistically significant differences in gene Ct values were observed between the paired upper and lower respiratory tract samples, except in the N gene for nasopharyngeal swab and sputum samples. Our study showed that clinical laboratories in Korea have rapidly expanded their testing capacities in response to the COVID-19 outbreak, with a peak daily capacity of 34,193 tests. Rapid expansion in testing capacity is a critical component of the national response to the ongoing pandemic.

Betacoronavirus/genética , Servicios de Laboratorio Clínico/estadística & datos numéricos , Infecciones por Coronavirus/diagnóstico , Neumonía Viral/diagnóstico , Betacoronavirus/aislamiento & purificación , Infecciones por Coronavirus/virología , Humanos , Laboratorios de Hospital , Pandemias , Neumonía Viral/virología , ARN Replicasa/genética , ARN Viral/genética , ARN Viral/metabolismo , Reacción en Cadena en Tiempo Real de la Polimerasa , República de Corea , Proteínas del Envoltorio Viral/genética , Proteínas Virales/genética
Spectrochim Acta A Mol Biomol Spectrosc ; 244: 118825, 2021 Jan 05.
Artículo en Inglés | MEDLINE | ID: mdl-32866803


Novel antiviral active molecule 2- [(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-(4-fluoro- phenyl)acetamide has been synthesised and characterized by FT-IR and FT-Raman spectra. The equilibrium geometry, natural bond orbital calculations and vibrational assignments have been carried out using density functional B3LYP method with the 6-311G++(d,p) basis set. The complete vibrational assignments for all the vibrational modes have been supported by normal coordinate analysis, force constants and potential energy distributions. A detailed analysis of the intermolecular interactions has been performed based on the Hirshfeld surfaces. Drug likeness has been carried out based on Lipinski's rule and the absorption, distribution, metabolism, excretion and toxicity of the title molecule has been calculated. Antiviral potency of 2- [(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-(4-fluoro-phenyl) acetamide has been investigated by docking against SARS-CoV-2 protein. The optimized geometry shows near-planarity between the phenyl ring and the pyrimidine ring. Differences in the geometries due to the substitution of the most electronegative fluorine atom and intermolecular contacts due to amino pyrimidine were analyzed. NBO analysis reveals the formation of two strong stable hydrogen bonded N-H···N intermolecular interactions and weak intramolecular interactions C-H···O and N-H···O. The Hirshfeld surfaces and consequently the 2D-fingerprint confirm the nature of intermolecular interactions and their quantitative contributions towards the crystal packing. The red shift in N-H stretching frequency exposed from IR substantiate the formation of N-H···N intermolecular hydrogen bond. Drug likeness and absorption, distribution, metabolism, excretion and toxicity properties analysis gives an idea about the pharmacokinetic properties of the title molecule. The binding energy -8.7 kcal/mol of the nonbonding interaction present a clear view that 2- [(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-(4-fluoro- phenyl) acetamide can irreversibly interact with SARS-CoV-2 protease.

Antivirales/química , Betacoronavirus/efectos de los fármacos , Infecciones por Coronavirus/tratamiento farmacológico , Pandemias , Neumonía Viral/tratamiento farmacológico , Inhibidores de Proteasas/química , Proteínas no Estructurales Virales/antagonistas & inhibidores , Antivirales/farmacocinética , Betacoronavirus/enzimología , Cristalografía por Rayos X , Cisteína Endopeptidasas , Humanos , Modelos Moleculares , Simulación del Acoplamiento Molecular , Estructura Molecular , Dinámicas no Lineales , Inhibidores de Proteasas/farmacocinética , Conformación Proteica , Teoría Cuántica , Espectroscopía Infrarroja por Transformada de Fourier , Espectrometría Raman , Termodinámica , Vibración
Artículo en Inglés | MEDLINE | ID: mdl-32730915


In December 2019, the first case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) infection was reported. In only few weeks it has caused a global pandemic, with mortality reaching 3.4%, mostly due to a severe pneumonia. However, the impact of SARS-CoV-2 virus on the central nervous system (CNS) and mental health outcomes remains unclear. Previous studies have demonstrated the presence of other types of coronaviruses in the brain, especially in the brainstem. There is evidence that the novel coronavirus can penetrate CNS through the olfactory or circulatory route as well as it can have an indirect impact on the brain by causing cytokine storm. There are also first reports of neurological signs in patients infected by the SARS-Cov-2. They show that COVID-19 patients have neurologic manifestations like acute cerebrovascular disease, conscious disturbance, taste and olfactory disturbances. In addition, there are studies showing that certain psychopathological symptoms might appear in infected patients, including those related to mood and psychotic disorders as well as post-traumatic stress disorder. Accumulating evidence also indicates that the pandemic might have a great impact on mental health from the global perspective, with medical workers being particularly vulnerable. In this article, we provide a review of studies investigating the impact of the SARS-CoV-2 on the CNS and mental health outcomes. We describe neurobiology of the virus, highlighting the relevance to mental disorders. Furthermore, this article summarizes the impact of the SARS-CoV-2 from the public health perspective. Finally, we present a critical appraisal of evidence and indicate future directions for studies in this field.

Infecciones por Coronavirus/psicología , Trastornos Mentales/psicología , Salud Mental , Neumonía Viral/psicología , Betacoronavirus , Encéfalo/virología , Infecciones por Coronavirus/complicaciones , Humanos , Trastornos Mentales/complicaciones , Trastornos Mentales/etiología , Enfermedades del Sistema Nervioso/etiología , Pandemias , Neumonía Viral/complicaciones , Resultado del Tratamiento
Artículo en Inglés | MEDLINE | ID: mdl-32771337


BACKGROUND: Psychological suffering by health professionals may be associated with the uncertainty of a safe workplace. Front-line professionals exposed and involved in the diagnosis and treatment of COVID-19 patients are more susceptible. METHOD: This review was conducted based on papers that were published at MEDLINE, BMJ, PsycINFO, and LILACS, the according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyzes (PRISMA). RESULTS: Health professionals had a higher level of anxiety (13.0 vs. 8.5%, p < 0.01, OR = 1.6152; 95%CI 1.3283 to 1.9641; p < 0.0001) and depression 12.2 vs. 9.5%; p = 0.04; OR = 1.3246; 95%CI 1.0930 to 1.6053; p = 0.0042), besides somatizations and insomnia compared to professionals from other areas. CONCLUSION: Health professionals, regardless of their age, showed significant levels of mental disorders. We observed a prevalence of anxiety and depression. Insomnia was a risk factor for both.

Infecciones por Coronavirus , Personal de Salud/psicología , Trastornos Mentales/etiología , Trastornos Mentales/psicología , Enfermedades Profesionales/etiología , Enfermedades Profesionales/psicología , Pandemias , Neumonía Viral , Humanos , Trastornos Mentales/epidemiología , Enfermedades Profesionales/epidemiología , Prevalencia , Estrés Psicológico
Artículo en Inglés | MEDLINE | ID: mdl-32777327


BACKGROUND: Health professionals are key personnel to containing infectious diseases like COVID-19. In the face of long work shifts (that reach 16 h per day on average), the risk of getting infected by a high-infectious disease and the lack of enough biological protection measures, mental suffering among health professionals suddenly became evident. METHOD: We carried out an updated meta-analysis to investigate the psychiatric impacts on health professionals in the face of the physical and psychological conditions to which they are subjected due to the high demands of the COVID-19 pandemic. Papers were researched in four databases from December 2019 to April 2020. In total, eight papers were included in the study. RESULTS: Health professionals working to fight COVID-19 are being more severely affected by psychiatric disorders associated with depression, anxiety, distress and insomnia, stress, and indirect traumatization than other occupational groups. No significant differences were observed in the publication bias. CONCLUSION: There is a strong association between health professionals and COVID-19 in terms of psychiatric repercussions. Our meta-analysis showed that health professionals have a higher level of indirect traumatization, in which the level of damage exceeds psychological and emotional tolerance and indirectly results in psychological abnormalities. The incidence of obsessive-compulsive traces and somatizations was higher in situations involving front-line professionals.

Infecciones por Coronavirus , Trastornos Mentales/etiología , Trastornos Mentales/psicología , Enfermedades Profesionales/etiología , Enfermedades Profesionales/psicología , Pandemias , Neumonía Viral , Ansiedad/etiología , Ansiedad/psicología , Depresión/etiología , Depresión/psicología , Personal de Salud , Humanos , Distrés Psicológico , Trastornos del Inicio y del Mantenimiento del Sueño/etiología , Trastornos del Inicio y del Mantenimiento del Sueño/psicología , Estrés Psicológico/epidemiología
An. pediatr. (2003. Ed. impr.) ; 92(4): 241.e1-241.e11, abr. 2020. mapas, graf, tab
Artículo en Español | IBECS | ID: ibc-186847


El 31 de diciembre de 2019, la Comisión Municipal de Salud y Sanidad de Wuhan (provincia de Hubei, China) informó sobre la existencia de 27 casos de neumonía de etiología desconocida con inicio de síntomas el 8 de diciembre, incluyendo 7 casos graves, con exposición común a un mercado de marisco, pescado y animales vivos en la ciudad de Wuhan. El 7 de enero de 2020, las autoridades chinas identificaron como agente causante del brote un nuevo tipo de virus de la familia Coronaviridae, denominado temporalmente «nuevo coronavirus», 2019-nCoV. El 30 de enero de 2020 la Organización Mundial de la Salud (OMS) declara el brote una Emergencia Internacional. El día 11 de febrero la OMS le asigna el nombre de SARS-CoV2 e infección COVID-19 (Coronavirus Infectious Disease). El Ministerio de Sanidad convoca a las Sociedades de Especialidades para la elaboración de un protocolo clínico de manejo de la infección. La Asociación Española de Pediatría nombra un grupo de trabajo de las Sociedades de Infectología Pediátrica y Cuidados Intensivos Pediátricos que se encargan de elaborar las presentes recomendaciones con la evidencia disponible en el momento de su realización

On 31 December 2019, the Wuhan Municipal Committee of Health and Healthcare (Hubei Province, China) reported that there were 27 cases of pneumonia of unknown origin with symptoms starting on the 8 December. There were 7 serious cases with common exposure in market with shellfish, fish, and live animals, in the city of Wuhan. On 7 January 2020, the Chinese authorities identified that the agent causing the outbreak was a new type of virus of the Coronaviridae family, temporarily called «new coronavirus», 2019-nCoV. On January 30th, 2020, the World Health Organisation (WHO) declared the outbreak an International Emergency. On 11 February 2020 the WHO assigned it the name of SARS-CoV2 and COVID-19 (SARS-CoV2 and COVID-19). The Ministry of Health summoned the Specialties Societies to prepare a clinical protocol for the management of COVID-19. The Spanish Paediatric Association appointed a Working Group of the Societies of Paediatric Infectious Diseases and Paediatric Intensive Care to prepare the present recommendations with the evidence available at the time of preparing them

Humanos , Lactante , Preescolar , Niño , Adolescente , Infecciones por Coronavirus/diagnóstico , Infecciones por Coronavirus/terapia , Neumonía Viral/diagnóstico , Neumonía Viral/terapia , Coronavirus/clasificación , Coronavirus/genética , Reacción en Cadena en Tiempo Real de la Polimerasa , Índice de Severidad de la Enfermedad , Sociedades Médicas , España
Texto & contexto enferm ; 29: e20200119, Jan.-Dec. 2020.
Artículo en Inglés | LILACS, BDENF - Enfermería | ID: biblio-1115946


ABSTRACT Objective: to describe the actions performed by nurses from the mobile pre-hospital service before, during, and after consultations and transfers of suspected and/or confirmed patients of Covid-19, and the limitations found by these professionals on reducing exposure to the disease. Method: a descriptive-reflective study about the actions performed by nurses from the mobile pre-hospital service in a capital city in southern Brazil to increase safety during consultations or transfers of suspected and/or confirmed patients of Covid-19. Results: the study allowed us to reflect on the multidimensionality of actions necessary for the prevention and control of the pandemic. Attitudes were identified to ensure instrumental safety in mobile units, professional safety, and patient safety in mobile pre-hospital care. Conclusion: regarding the nurses, concern with the safety of the professionals and patients was identified, since they adopted conducts for the prevention and control of the pandemic through the use of equipment, materials, and preparation of the ambulance. Subjective aspects of the professionals involved must be considered, such as technical and psychological preparation, which is a fundamental aspect both for serving the population and for the safety of the patient and the professional in terms of exposure to the virus.

RESUMEN Objetivo: describir las acciones llevadas a cabo por enfermeros del servicio prehospitalario móvil antes, durante y después de consultas y transferencias de pacientes sospechosos y/o confirmados respecto del Covid-19 y las limitaciones encontradas por estos profesionales para reducir la exposición a la enfermedad. Método: estudio descriptivo-reflexivo sobre las acciones realizadas por enfermeros del servicio móvil prehospitalario en una ciudad capital del sur de Brasil para aumentar la seguridad durante las consultas o transferencias de pacientes sospechosos y / o confirmados de Covid-19. Resultados: el estudio nos permitió reflexionar sobre el carácter multidimensional de las acciones necesarias para la prevención y el control de la pandemia. Se identificaron conductas para garantizar la seguridad instrumental en las unidades móviles, la seguridad profesional y la seguridad del paciente en la atención prehospitalaria móvil. Conclusión: de parte de los enfermeros, se identificó una preocupación por la seguridad de los profesionales y pacientes, ya que adoptaron conductas para la prevención y el control de la pandemia mediante el uso de equipos, materiales y preparación de la ambulancia. Se deben considerar los aspectos subjetivos de los profesionales involucrados, como la preparación técnica y psicológica, que es un aspecto fundamental tanto para atender a la población como para la seguridad del paciente y del profesional en términos de exposición al virus.

RESUMO Objetivo: descrever as ações realizadas por enfermeiros do serviço pré-hospitalar móvel antes, durante e após atendimentos e transferências de pacientes suspeitos e/ou confirmados para Covid-19 e as limitações encontradas por esses profissionais para diminuir a exposição à doença. Método: estudo descritivo-reflexivo acerca das ações realizadas por enfermeiros do serviço pré-hospitalar móvel de uma capital no Sul do Brasil para aumentar a segurança durante os atendimentos ou transferências de pacientes suspeitos e/ou confirmados para Covid-19. Resultados: o estudo permitiu refletir sobre a multidimensionalidade de ações necessárias para prevenção e controle da pandemia. Foram identificadas condutas para garantir a segurança instrumental nas unidades móveis, a segurança profissional e a segurança do paciente em atendimento pré-hospitalar móvel. Conclusão: por parte dos enfermeiros, identificou-se preocupação com a segurança dos profissionais e pacientes, uma vez que adotaram condutas para a prevenção e controle da pandemia mediante a utilização de equipamentos, materiais e preparo da ambulância. Aspectos subjetivos dos profissionais envolvidos devem ser considerados, como o preparo técnico e psicológico, sendo este um aspecto fundamental tanto para o atendimento à população como para a segurança do paciente e do profissional na exposição ao vírus.

Humanos , Enfermería de Urgencia , Infecciones por Coronavirus , Pandemias , Seguridad del Paciente , Enfermeras Practicantes , Atención de Enfermería
Texto & contexto enferm ; 29: e20200150, Jan.-Dec. 2020. tab, graf
Artículo en Inglés | LILACS, BDENF - Enfermería | ID: biblio-1115945


ABSTRACT Objective: to describe Covid-19 mobile applications available for download on smartphones. Method: a cross-sectional study with 52 mobile applications on Covid-19, obtained from virtual stores for smartphones with Android and iOS operating systems. Fisher's exact test and Cramér's V were used. Results: of the applications, 45 (86.6%) were developed in 2020, 51 (98.1%) were free, and 49 (94.2%) did not have accessibility for people with disabilities. It was observed that, in 23 countries, 17 (32.7%) applications in English and 14 (26.9%) in Portuguese were created, with a choice of 11 languages, relating to nine subthemes on Covid-19, the majority on "case monitoring" and "symptoms, prevention, and care", with 17 (32.7%) each. There was an association between the target audience and the subtheme of "symptoms, prevention, and care", and between patient monitoring and professional training. Conclusion: Covid-19 mobile applications were available in countries on five continents, in the main languages of communication and free of charge; however, with limited accessibility for people with disabilities.

RESUMEN Objetivo: describir aplicaciones móviles sobre Covid-19 disponibles para descargar en teléfonos inteligentes. Método: estudio transversal realizado con 52 aplicaciones móviles sobre Covid-19 obtenidas en las tiendas virtuales para teléfonos inteligentes con sistemas operativos Android e iOS. Se emplearon la Prueba Exacta de Fisher y el coeficiente V de Cramér. Resultados: del total de aplicaciones, 45 (86,6%) fueron desarrolladas en el año 2020, 51 (98,1%) eran gratuitas, y 49 (94,2%) no ofrecían accesibilidad para personas con discapacidades. Se observó que, en 23 países, se diseñaron diversas aplicaciones, 17 (32,7%) en inglés y 14 (26,9%) en portugués, con opción de 11 idiomas, relacionadas con nueve subtemas sobre Covid-19. La mayoría sobre "monitorización de casos" y sobre "síntomas, prevención y cuidados", con 17 (32,7%) aplicaciones en cada subtema. Se registró una asociación entre el público objetivo y el subtema de "síntomas, prevención y cuidados", y también entre la monitorización de pacientes y la capacitación profesional. Conclusión: se registró disponibilidad de aplicaciones móviles sobre Covid-19 en países de los cinco continentes, en los principales idiomas de comunicación, y en forma gratuita; no obstante, con accesibilidad limitada para personas con discapacidades.

RESUMO Objetivo: descrever aplicativos móveis sobre Covid-19 disponíveis para download em smartphones. Método: estudo transversal com 52 aplicativos móveis sobre Covid-19, obtidos nas lojas virtuais para smartphones com sistema operacional Android e iOS. Utilizou-se o Teste Exato de Fisher e V de Cramér. Resultados: dos aplicativos, 45 (86,6%) foram desenvolvidos em 2020, 51 (98,1%) eram gratuitos e 49 (94,2%) não possuíam acessibilidade para pessoas com deficiência. Observou-se que foram criados, em 23 países - 17 (32,7%) em inglês e 14 (26,9%) em português, com opção de 11 idiomas, aplicativos referentes a nove subtemas sobre a Covid-19, a maioria sobre "monitoramento de casos" e "sintomas, prevenção e cuidados", com 17 (32,7%) cada. Ocorreu associação entre o público-alvo e o subtema "sintomas prevenção e cuidados", e entre monitoramento de pacientes e capacitação profissional. Conclusão: os aplicativos móveis sobre Covid-19 encontravam-se disponíveis em países dos cinco continentes, nos principais idiomas de comunicação, de forma gratuita, entretanto, com escassa acessibilidade para pessoas com deficiência.

Humanos , Tecnología , Infecciones por Coronavirus , Aplicaciones Móviles , Teléfono Inteligente , Educación en Salud
Texto & contexto enferm ; 29: e20200106, Jan.-Dec. 2020. tab, graf
Artículo en Inglés | LILACS, BDENF - Enfermería | ID: biblio-1101977


ABSTRACT Objective: to analyze the COVID-19 pandemic and what we have (re)learned from the world experience of adopting prevention measures recommended by the World Health Organization as well as the epidemiological overview in the world, in Latin America and in Brazil. Results: the World Health Organization has pointed out that the path to reduce the speed of circulation of the virus, control and decrease in the number of cases and deaths resulting from this pandemic can only be accomplished with mass adoption of fundamental measures that include hand hygiene, alcohol gel use, cough etiquette, cleaning surfaces, avoiding agglomerations and social distancing. The epidemiological curve of the disease clearly shows the devastating proportions in Italy, Spain and the United States, surpassing China in death records, due to the delay in adopting the aforementioned measures. In Brazil, the rapid progression in relation to the world and Latin America points to an important increase in the number of cases. Conclusion: this is possibly the most serious pandemic in recent human history, and its course can be influenced by the rigor in adopting individual and collective behavioral measures.

RESUMEN Objetivo: analizar la pandemia de COVID-19 y lo que hemos (re)aprendido de la experiencia mundial para la adopción de las medidas de prevención recomendadas por la Organización Mundial de la Salud, así como el panorama epidemiológico en el mundo, en América Latina y en Brasil. Resultados: la Organización Mundial de la Salud ha señalado que el camino hacia la reducción de la velocidad de circulación del virus, el control y la reducción del número de casos y muertes resultantes de esta pandemia solo se puede lograr con la adopción masiva de medidas fundamentales que incluyan la higiene de las manos, uso de alcohol en gel, etiqueta respiratoria, limpieza de superficies, evitando hacinamiento y distancia social. La curva epidemiológica de la enfermedad muestra claramente las proporciones devastadoras en Italia, España y Estados Unidos, superando a China en los registros de defunciones, debido a la demora en la adopción de estas medidas. En Brasil, la rápida progresión en relación con el mundo y América Latina apunta a un aumento importante en el número de casos. Conclusión: esta pandemia es posiblemente la más grave en la historia humana reciente y su curso puede verse influenciado por el rigor en la adopción de medidas de comportamiento individuales y colectivas.

RESUMO Objetivo: analisar a pandemia da Covid-19 e o que temos (re)aprendido com a experiência mundial para adoção das medidas de prevenção preconizadas pela Organização Mundial de Saúde bem como o panorama epidemiológico no mundo, na América Latina e no Brasil. Resultados: a Organização Mundial de Saúde tem apontado que o caminho para a redução da velocidade de circulação do vírus, o controle e queda do número de casos e óbitos decorrentes dessa pandemia só poderá ser alcançado com adoção em massa de medidas fundamentais que incluem higienização das mãos, uso do álcool em gel, etiqueta respiratória, limpeza de superfícies, evitar aglomerações e distanciamento social. A curva epidemiológica da doença mostra claramente as proporções devastadoras na Itália, Espanha e nos Estados Unidos, superando a China em registros de óbitos, devido ao atraso na adoção dessas medidas. No Brasil, a progressão rápida em relação ao mundo e à América Latina aponta um importante aumento do número de casos. Conclusão: essa pandemia possivelmente é a mais grave da história recente da humanidade e seu curso pode ser influenciado pelo rigor na adoção de medidas comportamentais individuais e coletivas.

Humanos , Infecciones por Coronavirus , Prevención de Enfermedades , Pandemias , Equipo de Protección Personal , Betacoronavirus , Aislamiento de Pacientes , Distancia Social , Conducta , Educación en Salud
Rev. enferm. UERJ ; 28: 49570, jan.-dez. 2020.
Artículo en Inglés, Portugués | LILACS, BDENF - Enfermería | ID: biblio-1094832


Objetivo: discutir as experiências e contradições no controle da pandemia de Covid-19 sob a perspectiva da epidemiologia e das políticas públicas brasileiras. Conteúdo: o debate apresentado divide-se em duas seções: a primeira traça a reflexão dos parâmetros epidemiológicos sobre a curva epidêmica do SARS-CoV-2, bem como as experiências internacionais para o controle deste fenômeno. A segunda, ancorada nas políticas públicas brasileiras, apresenta uma análise comparada das experiências nacionais e internacionais, discutindo os potenciais reflexos sobre a pandemia, considerando algumas especificidades sociais. Conclusão: frente à impossibilidade de redução de pessoas susceptíveis por meio de estratégias vacinais, a redução da velocidade da curva epidêmica precisa ocorrer por meio de ações de isolamento físico social. Ademais, a construção de políticas públicas que visem a proteção ao trabalhador e a ampliação do investimento no setor saúde são medidas urgentes.

Objective: to discuss experiences and contradictions in the control of the Covid-19 pandemic from the perspective of epidemiology and Brazilian public policies. Content: the discussion presented is divided into two sections: the first one present epidemiological parameters on the epidemic curve of SARS-CoV-2, as well as the international experiences for the control of this phenomenon. The second, anchored in the Brazilian public policies, presents a comparative analysis of national and international experiences, discussing the potential impacts on the pandemic, considering some specific social issues. Conclusion: in the face of impossibility of reducing susceptible people through vaccination strategies, the reduction of the speed of the epidemic curve needs to occur through actions of social distance. In addition, the construction of public policies aimed at protecting workers and expanding investment in the health sector are urgent measures.

Objetivo: discutir las experiencias y contradicciones en el control de la pandemia Covid-19 desde la perspectiva de la epidemiología brasileña y las políticas públicas. Contenido: el debate presentado se divide en dos secciones. El primero traza la reflexión de los parámetros epidemiológicos en la curva epidémica del SARS-CoV-2, así como las experiencias internacionales para el control de este fenómeno. El segunda seccione, anclada en las políticas públicas brasileñas, presenta un análisis comparativo de las experiencias nacionales e internacionales, discutiendo los posibles impactos en la pandemia, considerando algunas especificidades sociales brasileñas. Conclusión: dada la imposibilidad de reducir a las personas susceptibles a través de estrategias de vacunación, la reducción de la velocidad de la curva epidémica debe ocurrir a través de acciones de aislamiento social y físico. Además, la construcción de políticas públicas destinadas a proteger a los trabajadores y ampliar la inversión en el sector de la salud son medidas urgentes.

Humanos , Neumonía Viral , Infecciones por Coronavirus/economía , Infecciones por Coronavirus/epidemiología , Políticas Públicas de Salud , Pandemias , Política Pública , Betacoronavirus