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1.
Braz. j. oral sci ; 21: e226698, jan.-dez. 2022. ilus
Artículo en Inglés | LILACS, BBO - Odontología | ID: biblio-1393366

RESUMEN

Aim: To evaluate the psychological impact of COVID-19 on undergraduate and graduate students of the Dental School of Ribeirão Preto, University of São Paulo. Methods: Three questionnaires were used: sociodemographic, WHO Abbreviated Quality of Life Inventory, and General Anxiety Disorder-7. Data were analyzed using Graph Pad Prism 7a (α = 5%). Mann-Whitney or Kruskal-Wallis and Dunn post-tests were used for statistical comparisons. The Spearman test was used as the correlation test. Results: 257 students responded to the online form that assessed their quality of life and anxiety level. On a scale from 1 to 100, with 100 being the best quality of life, the average obtained was 64.71 (± 13.36). In addition, 87.6% of the students rated their quality of life as good or very good. 74.7% reported good or very good health. The anxiety analysis resulted in an average of 10.04 (± 4.5), indicating moderate anxiety levels. There was an inversely proportional correlation between age and degree of anxiety (p = 0.008, r = -0.1628) and self-perceived learning and student commitment (r = 0.69). Conclusion: Despite the good quality of life and the students' good self-perception of health, they showed a moderate degree of anxiety during the social distancing caused by COVID-19, also demonstrating a decrease in interest and commitment during distance education


Asunto(s)
Humanos , Masculino , Femenino , Adulto , Trastornos de Ansiedad/diagnóstico , Estudiantes de Odontología , Infecciones por Coronavirus , Cuestionario de Salud del Paciente , Distanciamiento Físico , COVID-19 , Calidad de Vida , Autoimagen
2.
rev.cuid. (Bucaramanga.2010) ; 13(1): 1-16, 20221213.
Artículo en Portugués | LILACS, BDENF - Enfermería, COLNAL | ID: biblio-1369178

RESUMEN

Introdução: Necessitando de medidas de combate à pandemia por SARS-CoV-2, a Organização Mundial da Saúde orientou o distanciamento social como estratégia para mitigar seus impactos. Dentre as medidas adotadas para evitar aglomerações, universidades se adaptaram para modalidade de ensino online. O objetivo é refletir sobre a influência do distanciamento social por covid-19, na rotina de estudantes de ciências da saúde. Materiais e Métodos: É uma revisão integrativa, com buscas nas bases de dados Pubmed, MEDLINE, LILACS, WHO COVID, bioRxiv, e medRxiv, nos sites da Pubmed, BVS e Portal de buscas da Organização Mundial da Saúde para covid-19, com descritores nas seguintes combinações: "Infecções por coronavírus e estudantes de ciências de saúde" e "Covid-19 e estudantes de ciências de saúde". Inicialmente encontrou-se 1069 artigos. Resultados: Após refinamento 23 artigos compuseram o estudo. Os resultados foram categorizados como 1-desordens nas competências emocionais, 2-ensino, 3-alimentação, sono e atividade física e 4-efeitos de natureza diversas. Manifestações frequentes: ansiedade, depressão, estresse, incerteza e angústia, mudanças no sono e atividade física. Vantagem ou desvantagem do ensino online, teve percentual de 50% cada. Conclusão: Conhecer como o distanciamento social influenciou na rotina dos estudantes é relevante para que as universidades desenvolvam programas de suporte para as necessidades apresentadas na realidade atual, e consigam projetar programas de enfrentamento para futuras crises epidêmicas, auxiliando na redução dos impactos resultantes.


Introduction: In response to the SARS-CoV-2 pandemic, the World Health Organization recommended social distancing as a strategy to mitigate the impacts of the coronavirus disease. Among measures adopted to avoid crowds, universities then switched to virtual education. The objective is to reflect on the influence of social distancing during COVID-19 on the daily routine of health sciences students. Materials and methods: A systematic literature review was conducted by searching on PubMed, MEDLINE, LILACS, bioRxiv, medRxiv, as well as BVS and the World Health Organization site for COVID-19 (WHO COVID-19) databases, using combined descriptors such as "coronavirus infections and health science students" and "COVID-19 and health science students". A total of 1069 articles were initially found, being later refined to 23 for the study. Results were classified into 1) emotional competence disorder, 2) education, 3) eating, sleep and physical activity, and 4) various kind of impacts with frequent manifestations of anxiety, depression, stress, uncertainty distress and changes in physical activity and sleep habits. Student dropout in virtual programs is about 50% in all cases. Conclusions: Knowing how social distancing influenced the daily routine of college students is important for universities to develop support programs tailored to current reality needs and implement future epidemic preparedness programs, helping reduce possible impacts.


Introducción: Ante la necesidad de combatir la pandemia por SARS-CoV-2, la Organización Mundial de la Salud recomendó el distanciamiento social como estrategia para mitigar los impactos de la enfermedad. Entre las medidas adoptadas para evitar aglomeraciones, las universidades se han adaptado a la modalidad de educación virtual. El objetivo es reflexionar sobre la influencia del distanciamiento social por COVID-19 en la rutina de los estudiantes de ciencias de la salud. Materiales y métodos: Se realizó una revisión sistemática de la literatura a través de búsquedas en PubMed, MEDLINE, LILACS, bioRxiv, medRxiv, así como en BVS y el portal de búsqueda de la Organización Mundial de la Salud para COVID-19 (WHO COVID-19), con descriptores combinados de la siguiente forma: "infecciones por coronavirus y estudiantes de ciencias de la salud" y "COVID-19 y estudiantes de ciencias de la salud". Se encontraron 1069 artículos inicialmente, que luego fueron depurados a 23 para conformar el estudio. Los resultados se categorizaron en: 1) trastorno en las competencias emocionales, 2) educación, 3) alimentación, sueño y actividad física, y 4) efectos de diversa índole, con manifestaciones frecuentes de ansiedad, depresión, estrés, incertidumbre y angustia, y cambios en el sueño y la actividad física. La deserción escolar en entornos virtuales es del 50% en todos los casos. Conclusiones: Es importante saber la forma en la que el distanciamiento social influyó en la rutina de los estudiantes, para que así las universidades logren desarrollar programas de apoyo que se ajusten a las necesidades de la realidad actual e implementar programas de respuesta a futuras crisis epidemiológicas, lo que ayudaría a reducir los posibles impactos.


Asunto(s)
Humanos , Masculino , Femenino , Aislamiento Social , Salud del Estudiante , Infecciones por Coronavirus , Pandemias
3.
PLoS One ; 17(9): e0274490, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36107832

RESUMEN

The straw-colored fruit bat (Eidolon helvum) is a pteropodid whose conservation is crucial for maintaining functional connectivity of plant populations in tropical Africa. Land conversion has pushed this species to adapt to roosting in urban centers across its range. These colonies often host millions of individuals, creating intensive human-bat contact interfaces that could facilitate the spillover of coronaviruses shed by these bats. A better understanding of coronavirus dynamics in these roosts is needed to identify peak times of exposure risk in order to propose evidence-based management that supports safe human-bat coexistence, as well as the conservation of this chiropteran. We studied the temporal patterns of coronavirus shedding in E. helvum, by testing thousands of longitudinally-collected fecal samples from two spatially distant urban roosts in Ghana and Tanzania. Shedding of coronaviruses peaked during the second part of pup weaning in both roosts. Assuming that coronavirus shedding is directly related to spillover risk, our results indicate that exposure mitigation should target reducing contact between people and E. helvum roosts during the pup "weaning" period. This recommendation can be applied across the many highly-populated urban sites occupied by E. helvum across Africa.


Asunto(s)
Quirópteros , Infecciones por Coronavirus , Coronavirus , Animales , Infecciones por Coronavirus/epidemiología , Infecciones por Coronavirus/veterinaria , Ghana , Humanos , Estaciones del Año
4.
Science ; 377(6612): 1245, 2022 09 16.
Artículo en Inglés | MEDLINE | ID: mdl-36108021

RESUMEN

Initiative to explore whether coronavirus lingers in patients.


Asunto(s)
COVID-19 , Infecciones por Coronavirus , COVID-19/complicaciones , Infecciones por Coronavirus/epidemiología , Humanos
5.
6.
Front Immunol ; 13: 972499, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36081520

RESUMEN

Porcine Deltacoronavirus (PDCoV), an enveloped positive-strand RNA virus that causes respiratory and gastrointestinal diseases, is widely spread worldwide, but there is no effective drug or vaccine against it. This study investigated the optimal Selenium Nano-Particles (SeNPs) addition concentration (2 - 10 µg/mL) and the mechanism of PDCoV effect on ST (Swine Testis) cell apoptosis, the antagonistic effect of SeNPs on PDCoV. The results indicated that 4 µg/mL SeNPs significantly decreased PDCoV replication on ST cells. SeNPs relieved PDCoV-induced mitochondrial division and antagonized PDCoV-induced apoptosis via decreasing Cyt C release and Caspase 9 and Caspase 3 activation. The above results provided an idea and experimental basis associated with anti-PDCoV drug development and clinical use.


Asunto(s)
Infecciones por Coronavirus , Coronavirus , Selenio , Enfermedades de los Porcinos , Animales , Apoptosis , Coronavirus/fisiología , Masculino , Dinámicas Mitocondriales , Porcinos
7.
Vet Microbiol ; 273: 109544, 2022 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-36049346

RESUMEN

Autophagy-related 4B (ATG4B) is found to exert a vital function in viral replication, although the mechanism through which ATG4B activates type-I IFN signaling to hinder viral replication remains to be explained, so far. The current work revealed that ATG4B was downregulated in porcine epidemic diarrhea virus (PEDV)-infected LLC-PK1 cells. In addition, ATG4B overexpression inhibited PEDV replication in both Vero cells and LLC-PK1 cells. On the contrary, ATG4B knockdown facilitated PEDV replication. Moreover, ATG4B was observed to hinder PEDV replication by activating type-I IFN signaling. Further detailed analysis revealed that the ATG4B protein targeted and upregulated the TRAF3 protein to induce IFN expression via the TRAF3-pTBK1-pIRF3 pathway. The above data revealed a novel mechanism underlying the ATG4B-mediated viral restriction, thereby providing novel possibilities for preventing and controlling PEDV.


Asunto(s)
Infecciones por Coronavirus , Virus de la Diarrea Epidémica Porcina , Enfermedades de los Porcinos , Animales , Chlorocebus aethiops , Infecciones por Coronavirus/veterinaria , Virus de la Diarrea Epidémica Porcina/genética , Transducción de Señal , Porcinos , Factor 3 Asociado a Receptor de TNF/genética , Células Vero , Replicación Viral
8.
Vet Res ; 53(1): 67, 2022 Sep 02.
Artículo en Inglés | MEDLINE | ID: mdl-36056449

RESUMEN

Middle East respiratory syndrome coronavirus (MERS-CoV) poses a serious threat to public health. Here, we established an ex vivo alpaca tracheal explant (ATE) model using an air-liquid interface culture system to gain insights into MERS-CoV infection in the camelid lower respiratory tract. ATE can be infected by MERS-CoV, being 103 TCID50/mL the minimum viral dosage required to establish a productive infection. IFNs and antiviral ISGs were not induced in ATE cultures in response to MERS-CoV infection, strongly suggesting that ISGs expression observed in vivo is rather a consequence of the IFN induction occurring in the nasal mucosa of camelids.


Asunto(s)
Camélidos del Nuevo Mundo , Infecciones por Coronavirus , Coronavirus del Síndrome Respiratorio de Oriente Medio , Animales , Antivirales , Bronquios , Infecciones por Coronavirus/veterinaria , Coronavirus del Síndrome Respiratorio de Oriente Medio/fisiología
9.
Cell Rep Med ; 3(9): 100735, 2022 Sep 20.
Artículo en Inglés | MEDLINE | ID: mdl-36075217

RESUMEN

We here investigate the impact of antiviral treatments such as remdesivir on intra-host genomic diversity and emergence of SARS-CoV2 variants in patients with a prolonged course of infection. Sequencing and variant analysis performed in 112 longitudinal respiratory samples from 14 SARS-CoV2-infected patients with severe disease progression show that major frequency variants do not generally arise during prolonged infection. However, remdesivir treatment can increase intra-host genomic diversity and result in the emergence of novel major variant species harboring fixed mutations. This is particularly evident in a patient with B cell depletion who rapidly developed mutations in the RNA-dependent RNA polymerase gene following remdesivir treatment. Remdesivir treatment-associated emergence of novel variants is of great interest in light of current treatment guidelines for hospitalized patients suffering from severe SARS-CoV2 disease, as well as the potential use of remdesivir to preventively treat non-hospitalized patients at high risk for severe disease progression.


Asunto(s)
COVID-19 , Infecciones por Coronavirus , Neumonía Viral , Adenosina Monofosfato/análogos & derivados , Alanina/análogos & derivados , Antivirales/efectos adversos , Betacoronavirus , COVID-19/tratamiento farmacológico , Infecciones por Coronavirus/tratamiento farmacológico , Progresión de la Enfermedad , Humanos , Pandemias , Neumonía Viral/inducido químicamente , ARN Viral/uso terapéutico , ARN Polimerasa Dependiente del ARN , SARS-CoV-2/genética
10.
Rev. clín. esp. (Ed. impr.) ; 222(7): 406-411, ago. - sept. 2022. tab
Artículo en Español | IBECS | ID: ibc-207423

RESUMEN

Fundamentos La pandemia por COVID-19 ha provocado cambios globales que afectan a la vida diaria de la población mundial, con un impacto directo sobre la salud física y mental de los individuos, así como en sus hábitos sociales y recreativos. Métodos Análisis retrospectivo de aspectos demográficos y clínicos de los pacientes atendidos por intoxicaciones agudas en un servicio de urgencias hospitalario durante 3 períodos distintos: prepandemia (2019), tras el confinamiento domiciliario (2020) y en el período pospandémico (2021), analizando en cada uno los meses de junio y julio. Resultados Se incluyeron 1.182 intoxicaciones agudas. En relación con la etapa prepandémica, el número de intoxicados disminuyó durante el confinamiento (2019: 1,9 vs. 2020: 1,5%; p<0,01), incrementándose la ratio varón/mujer (2,0 vs. 1,4; p=0,02) y la edad media (2019: 31,4 vs. 2020: 41,3; p<0,001), tendencia que se mantuvo en el año 2021 (38,3). La intoxicación con motivación suicida también aumentó en dicho período (2019: 8,71 vs. 2020: 21,0%; p<0,01), mientras que las lúdicas decrecieron (2019: 76,1 vs. 2020: 62,0%; p<0,01), con un aumento no significativo en el último año 2021 (69,0%; p=0,07). Conclusiones La pandemia por COVID-19 ha generado cambios clínicos y epidemiológicos en las intoxicaciones agudas atendidas en un servicio de urgencias hospitalario durante las distintas fases de la pandemia (AU)


Background The COVID-19 pandemic has caused global changes that affect the daily life of the world's population, with a direct impact on individuals’ physical and mental health as well as on their social and recreational habits. Methods This study aimed to retrospectively analyze the demographic and clinical characteristics of patients attended to for acute poisoning in a hospital emergency department (ED) at three different periods of time: pre-pandemic (2019), after strict lockdown of the population in Spain (2020), and post-pandemic (2021). We analyzed 2 months (June and July) in each period. Results A total of 1,182 cases of acute poisoning were included. Compared to the pre-pandemic period, during lockdown, the number of patients with acute poisoning decreased (2019: 1.9% vs. 2020: 1.5%; p<.01); the ratio of men to women increased (2.0 vs. 1.4; p=.02); and the mean age of patients increased (2019: 31.4 vs. 2020: 41.3; p<.001), a trend which continued in 2021 (38.3). Poisoning with suicidal intention also increased during the pandemic (2019: 8.71% vs. 2020: 21.0%; p<.01) whereas poisonings with a recreational intention declined (2019: 76.1% vs. 2020: 62.0%; p<.01) with a non-significant increase in 2021 (69.0%, p=.07). Conclusion The COVID-19 pandemic generated clinical and epidemiological changes in the acute poisonings attended to in a hospital emergency department during the various phases of the pandemic (AU)


Asunto(s)
Humanos , Masculino , Femenino , Adolescente , Adulto Joven , Adulto , Persona de Mediana Edad , Servicio de Urgencia en Hospital , Infecciones por Coronavirus/epidemiología , Neumonía Viral/epidemiología , Intoxicación/epidemiología , Pandemias , Estudios Retrospectivos , Enfermedad Aguda , España/epidemiología
14.
Clín. investig. arterioscler. (Ed. impr.) ; 34(5): 245-252, Sep-Oct 2022. graf, tab
Artículo en Español | IBECS | ID: ibc-207817

RESUMEN

Objetivos: El estudio MEMOGAL (NCT04319081) está dirigido a evaluar cambios en la función cognitiva en pacientes tratados con inhibidores de la PCSK9 (iPCSK9). Se realiza primer análisis: 1) discutir el papel de los farmacéuticos hospitalarios durante de la pandemia, así como evaluar el impacto de la misma en el control lipídico; 2) análisis descriptivo; 3) eficacia en reducción de colesterol-LDL (c-LDL) de alirocumab y evolocumab; y 4) reportar seguridad de los iPCSK9. Material y métodos: Se trata de un análisis prospectivo en vida real de pacientes tratados por primera vez con iPCSK9 en la práctica clínica habitual e incluidos en su primera dispensación en las consultas de farmacia de 12 hospitales de Galicia desde mayo de 2020-abril de 2021. Los valores basales de c-LDL son los previos al inicio del tratamiento con iPCSK9 y como seguimiento los valores a los 6 meses. Resultados: Se incluyeron 89 pacientes. El 86,5% con enfermedad cardiovascular y un 53,9% intolerancia a las estatinas. Un 78,8% de los pacientes fueron tratados con estatinas de alta intensidad. Las estatinas más usadas fueron rosuvastatina (34,1%) y atorvastatina (20,5%). El nivel basal de c-LDL fue 148mg/dl y de 71mg/dl al seguimiento. Los pacientes tratados con alirocumab (n=43) presentaban valores basales de 144mg/dl y de 73mg/dl al seguimiento y con evolocumab (n=46) de 151mg/dl basal y 69mg/dl al seguimiento. La reducción de c-LDL fue para evolocumab 51,21% y alirocumab 51,05%. El 43,1% presentaba a los 6 meses valores>70mg/dl, el 19,4% entre 55 y 69mg/dl y el 37,5%<55mg/dl. Los pacientes que obtuvieron una reducción>50% de c-LDL fueron el 58,3%. Los eventos adversos presentados fueron: reacción en el lugar de inyección (n=2), mialgias (n=1), síntomas pseudogripales (n=1) y deterioro neurocognitivo (n=1).(AU)


Objectives: MEMOGAL study (NCT04319081) is aimed at evaluating changes in cognitive function in patients treated with PCSK9 inhibitors (PCSK9i). This is the first analysis: (1) discussion about the role of the Hospital Pharmacists during the pandemic, and also the assessment of the impact of COVID-19 in the lipid control; (2) descriptive analysis; (3) effectiveness in LDL cholesterol (LDL-c) reduction of alirocumab and evolocumab; (4) communicate PCSK9i safety. Material and methods: It is a prospective Real-World Evidence analysis of patients that take PCSK9i for the first time in the usual clinical practice, and they are included after the first dispensation in the public pharmacy consultations of 12 Hospitals in Galicia from May 2020 to April 2021. Baseline values of LDL-c are the previous values before taking PCSK9 and the follow-up values are in 6 months time. Results: 89 patients were included. 86.5% with cardiovascular disease and 53.9% with statin intolerances. 78.8% of the patients were treated with high intensity statins. Statins most used were rosuvastatin (34.1%) and atorvastatin (20.5%). Baseline value of LDL-c was 148mg/dL and the follow-up value was 71mg/dL. The baseline value of patients treated with alirocumab (N=43) was 144mg/dL and 73mg/dL in the follow-up. With evolocumab (N=46) was 151mg/dL in basaline and 69mg/dL in follow-up. The LDLc- reduction was 51.21% with evolocumab and 51.05% with alirocumab. 43.1% of the patients showed values >70mg/dL in six month time; 19.4% between 69mg/dl and 55mg/dL and 37.5% <55mg/dL. 58.3% of the patients achieved a reduction >50% of LDL-c. The adverse events were: injection point reaction (N=2), myalgias (N=1), flu-like symptoms (N=1) and neurocognitive worsening (N=1).(AU)


Asunto(s)
Humanos , Femenino , Persona de Mediana Edad , Anciano , Lípidos , Virus del SRAS , Betacoronavirus , Infecciones por Coronavirus/prevención & control , Proproteína Convertasa 9 , Cognición , Farmacología , Evaluación de Síntomas , Estudios Prospectivos , Arteriosclerosis
16.
Sportis (A Coruña) ; 8(3): 370-395, Sept. 2022. tab
Artículo en Inglés, Español | IBECS | ID: ibc-207908

RESUMEN

En la actualidad los componentes psicológicos han alcanzado una importancia muy notable en la adquisición de comportamientos saludables. Por lo tanto, este estudio analiza las diferencias entre variables psicológicas que se relacionan con la práctica deportiva en estudiantes universitarios durante el confinamiento causado por la COVID-19. El estudio tuvo una muestra de 1239 participantes (765 varones y 474 mujeres), de edades comprendidas entre los 16 y 45 años (M = 21,44; DT = 3,94). Se utilizó un cuestionario que incluyó la Behavioral Regulation in Sport Questionnaire (BRSQ), la Escala de las Necesidades Psicológicas Básicas en el Ejercicio; la Escala de Autoeficacia para la Actividad Física; y la Escala de Grado de Compromiso Deportivo. Los resultados más relevantes muestran diferencias significativas (p<0,01) en favor del género masculino en casi todas las variables psicológicas excepto en la desmotivación, así mismo en lo que respecta a la motivación controlada y desmotivación, se encontraron diferencias significativas entre las localidades pequeñas y grandes, siendo los valores más altos en las primeras (p<0,05 y <0,01). Se discuten los resultados con objeto de determinar las diferencias en cuanto a qué componentes psicológicos permitirían plantear intervenciones que sean más efectivas para lograr la práctica regular de actividades deportivas así como su compromiso y adherencia, mediante el uso de estrategias que vayan encaminadas a fomentar la motivación autónoma de los universitarios y contrarrestar los efectos de la motivación controlada y la desmotivación. (AU)


Nowadays, psychological components have attained a very notable importance in the acquisition of healthy behaviours. Therefore, this study analyses the differences between psychological variables that are related to sports practice in university students during the confinement caused by COVID-19. The study had a sample of 1239 participants (765 males and 474 females), aged 16-45 years (M = 21.44, SD = 3.94). A questionnaire, which included the Behavioural Regulation in Sport Questionnaire (BRSQ), the Basic Psychological Needs in Exercise Scale; the Physical Activity Self-Efficacy Scale; and the Degree of Sport Commitment Scale, was used. The most relevant results show significant differences (p<0.01) in favour of the male gender in almost all psychological variables except demotivation. Likewise, with regard to controlled motivation and demotivation, significant differences were found between small and large localities, with higher values in the former (p<0.05 and <0.01). The results are discussed in order to determine the differences in terms of which psychological components would allow for interventions that might be more effective in achieving regular sport practice, commitment, and adherence through the use of strategies aimed at fostering autonomous motivation in university students and counteracting the effects of controlled motivation and demotivation. (AU)


Asunto(s)
Humanos , Adolescente , Adulto Joven , Adulto , Psicología del Deporte , Atletas , Pandemias , Infecciones por Coronavirus/epidemiología , Infecciones por Coronavirus/psicología , Epidemiología Descriptiva , Estudios Transversales , Ecuador , Universidades
17.
Sportis (A Coruña) ; 8(3): 491-513, Sept. 2022. tab
Artículo en Español | IBECS | ID: ibc-207915

RESUMEN

El 14 de marzo de 2020 se declaró el Estado de Alarma en todo el territorio español, sufriendo el sistema educativo un cambio que conllevó a reformular muchos aspectos del proceso de enseñanza-aprendizaje. En España, las Comunidades Autónomas (CCAA) asumieron la delegación de responsabilidades para actuar en su ámbito territorial y adaptar las restricciones por zonas territoriales en función de la incidencia de contagios por la Covid-19. Posteriormente, multitud de estudios abalaron la decisión del Ministerio de Educación y Formación Profesional para el curso 2020-2021, sobre la necesidad de la presencialidad de las clases, encomendando a las CCAA y centros educativos la concreción de planes de contingencia o protocolos de seguridad, con el objetivo de garantizar la máxima presencialidad posible del alumnado en Educación Secundaria. El objetivo de este trabajo es describir y conocer las dificultades que han tenido los docentes de Educación Física (EF) a la hora de impartir las clases a lo largo del curso escolar 2020-2021, con relación a cuatro dimensiones: práctica físico-deportiva, uso de instalaciones específicas, uso y limpieza de material y decisiones del equipo directivo respecto a la materia de EF. Se diseñó una encuesta ad hoc, participando un total de 740 docentes de EF de España repartidos por las 17 CCAA. Los resultados manifiestan una disminución del tiempo de compromiso motor, dificultades para trabajar algunos objetivos y criterios de evaluación por la imposibilidad de utilizar materiales o aulas específicas, como consecuencia de una disparidad de criterios y enfoques utilizados por las diferentes CCAA. (AU)


On March 14, 2020, a State of Alarm was declared throughout Spain, and the educational system underwent a change that led to the reformulation of many aspects of the teaching-learning process. In Spain, the Autonomous Communities (AACC) assumed the delegation of responsibilities to act in their territorial scope and adapt the restrictions by territorial areas according to the incidence of Covid-19 infections. Subsequently, many studies supported the decision of the Ministry of Education and Vocational Training for the academic year 2020-2021, on the need for the attendance of educational classes, entrusting each AACC and educational center to specify contingency plans or safety protocols, with the aim of ensuring the maximum possible attendance of students in Secondary Education. The aim of this work is to describe and learn about the difficulties encountered by Physical Education (PE) teachers when teaching during the 2020-2021 school year, in relation to four dimensions: time for physical-sports practice, use of facilities, use and cleaning of material, and decisions of the management team regarding the subject of PE. An ad hoc survey was designed, with the participation of a total of 740 PE teachers in Spain, distributed among the 17 AACC. The results show a decrease in motor engagement time, difficulties in working on some objectives and evaluation criteria due to the impossibility of using specific materials or classrooms, because of a disparity of criteria and approaches used by the different AACC. (AU)


Asunto(s)
Humanos , Adulto Joven , Adulto , Persona de Mediana Edad , Pandemias , Infecciones por Coronavirus/epidemiología , Educación y Entrenamiento Físico , Cuarentena , Instalaciones Deportivas y Recreativas , Encuestas y Cuestionarios , España
19.
Arch. bronconeumol. (Ed. impr.) ; 58(9): 649-659, Sept. 2022. graf, tab, ilus
Artículo en Inglés | IBECS | ID: ibc-207922

RESUMEN

Background: The clinical and epidemiological implications of abnormal immune responses in COVID-19 for latent tuberculosis infection (LTBI) screening are unclear.Methods: We reviewed QuantiFERON TB Gold Plus (QFT-Plus) results (36,709 patients) from July 2016 until October 2021 in Asturias (Spain). We also studied a cohort of ninety hospitalized patients with suspected/confirmed COVID-19 pneumonia and a group of elderly hospitalized patients with COVID-19 who underwent serial QFT-Plus and immune profiling testing.Results: The indeterminate QFT-Plus results rate went from 1.4% (July 2016 to November 2019) to 4.2% during the COVID-19 pandemic. The evolution of the number of cases with low/very low interferon-gamma (IFN-gamma) response in the mitogen tube paralleled the disease activity and number of deaths during the pandemic waves in our region (from March 2020 to October 2021). The percentages of positive QFT-plus patients did not significantly change before and during the pandemic (13.9% vs. 12.2%). Forty-nine patients from the suspected/confirmed COVID-19 pneumonia cohort (54.4%) had low/very low IFN-gamma response to mitogen, 22 of them (24.4%) had severe and critical pneumonia. None received immunosuppressants prior to testing. Abnormal radiological findings (P=0.01) but not COVID-19 severity was associated with low mitogen response. Immune profiling showed a reduction of CD8+T cells and a direct correlation between the number of EMRA CD8+T-cells and IFN-gamma response to mitogen (P=0.03).Conclusion: Low IFN-gamma responses in mitogen tube of QFT-Plus often occur in COVID-19 pneumonia, which is associated with a low number of an effector CD8+T-cell subset and does not seem to affect LTBI screening; however, this abnormality seems to parallel the dynamics of COVID-19 at the population level and its mortality. (AU)


Asunto(s)
Humanos , Pandemias , Infecciones por Coronavirus/epidemiología , Virus del SRAS , Tuberculosis Latente , 28599 , Hospitalización
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