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2.
Palmas, TO; Secretaria de Estado da Saúde; 20210000. 59 p. ilus.
Monografía en Portugués | LILACS, Coleciona SUS, CONASS, SES-TO | ID: biblio-1150754

RESUMEN

A organização do Coletivo da Educação Profissional em Saúde - EPS/Humanização no contexto da pandemia. Trata dos caminhos e pistas metodológicas para a estruturação do Planejamento, Monitoramento e Avaliação. Apresenta as memórias e instrumentos como dispositivo de PMA.


The organization of the Collective of Professional Education in Health - EPS / Humanization in the context of the pandemic. It deals with the methodological paths and clues for structuring Planning, Monitoring and Evaluation. It presents memories and instruments as a PMA device.


Asunto(s)
Humanos , Políticas, Planificación y Administración en Salud , Evaluación Educacional , Informes Anuales como Asunto , Gestión de la Información/educación , Educación Continua/tendencias
3.
J Am Acad Dermatol ; 84(4): 1037-1041, 2021 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-33316331

RESUMEN

The American Academy of Dermatology launched DataDerm in 2016 as the clinical data registry platform of the American Academy of Dermatology. DataDerm is approved by the Centers for Medicare & Medicaid Services as a Qualified Clinical Data Registry for the Merit-Based Incentive Payment System. The ultimate purpose of DataDerm is to provide dermatologists with a registry and database that will serve as a vehicle to advance the specialty in the domains of science, discovery, education, quality assessment, quality improvement, advocacy, and practice management. DataDerm is currently the largest clinical registry and database of patients receiving dermatologic care in the world. As of December 31, 2019, DataDerm contained data from 10,618,879 unique patients and 32,309,389 unique patient visits. Depending on the reporting period, 800 to 900 practices (representing 2400-2600 clinicians) actively participate in DataDerm by submitting data. This article provides the first of a planned series of annual updates of the status of DataDerm. The purpose of this article is to present the rationale for the creation, maintenance, history, and current status of DataDerm, as well as the future plans for DataDerm.


Asunto(s)
Academias e Institutos , Informes Anuales como Asunto , Bases de Datos Factuales , Dermatología , Sistema de Registros , Predicción , Humanos , Internacionalidad , Estados Unidos
6.
BMC Cardiovasc Disord ; 20(1): 448, 2020 10 19.
Artículo en Inglés | MEDLINE | ID: mdl-33070781

RESUMEN

The 2020 annual Congress of the European Society of Cardiology (ESC) was the first ever to be held virtually. Under the spotlight of 'the cutting edge of cardiology', exciting and ground-breaking cardiovascular (CV) science was presented both in basic and clinical research. This commentary summarizes essential updates from ESC 2020-The Digital Experience. Despite the challenges that coronavirus disease 2019 (COVID-19) has posed on the conduct of clinical trials, the ESC Congress launched the results of major studies bringing innovation to the field of general cardiology, cardiac surgery, heart failure, interventional cardiology, and atrial fibrillation. In addition to three new ESC guidelines updates, the first ESC Guidelines on Sports Cardiology and Exercise in Patients with Cardiovascular Disease were presented. As former ESC president, Professor Casadei undoubtedly pointed out the ESC Congress 2020 was a great success. During the ESC 2020 Congress, BMC Cardiovascular Disorders updated to seven journal sections including Arrhythmias and Electrophysiology, CV Surgery, Coronary Artery Disease, Epidemiology and Digital health, Hypertension and Vascular biology, Primary prevention and CV Risk, and Structural Diseases, Heart Failure, and Congenital Disorders. To conclude, an important take-home message for all CV health care professionals engaged in the COVID-19 pandemic is that we must foresee and be prepared to tackle the dramatic, long-term CV complications of COVID-19 patients.


Asunto(s)
Cardiología , Enfermedades Cardiovasculares , Infecciones por Coronavirus , Control de Infecciones/métodos , Pandemias , Neumonía Viral , Telecomunicaciones/organización & administración , Informes Anuales como Asunto , Betacoronavirus , COVID-19 , Cardiología/métodos , Cardiología/normas , Cardiología/tendencias , Enfermedades Cardiovasculares/clasificación , Enfermedades Cardiovasculares/epidemiología , Enfermedades Cardiovasculares/terapia , Congresos como Asunto , Infecciones por Coronavirus/epidemiología , Infecciones por Coronavirus/prevención & control , Europa (Continente) , Humanos , Pandemias/prevención & control , Neumonía Viral/epidemiología , Neumonía Viral/prevención & control , Guías de Práctica Clínica como Asunto , SARS-CoV-2 , Sociedades Médicas
7.
Ann Surg ; 272(4): 604-610, 2020 10.
Artículo en Inglés | MEDLINE | ID: mdl-32932316

RESUMEN

OBJECTIVES: Sepsis and sterile both release "danger signals' that induce the systemic inflammatory response syndrome (SIRS). So differentiating infection from SIRS can be challenging. Precision diagnostic assays could limit unnecessary antibiotic use, improving outcomes. METHODS: After surveying human leukocyte cytokine production responses to sterile damage-associated molecular patterns (DAMPs), bacterial pathogen-associated molecular patterns, and bacteria we created a multiplex assay for 31 cytokines. We then studied plasma from patients with bacteremia, septic shock, "severe sepsis," or trauma (ISS ≥15 with circulating DAMPs) as well as controls. Infections were adjudicated based on post-hospitalization review. Plasma was studied in infection and injury using univariate and multivariate means to determine how such multiplex assays could best distinguish infective from noninfective SIRS. RESULTS: Infected patients had high plasma interleukin (IL)-6, IL-1α, and triggering receptor expressed on myeloid cells-1 (TREM-1) compared to controls [false discovery rates (FDR) <0.01, <0.01, <0.0001]. Conversely, injury suppressed many mediators including MDC (FDR <0.0001), TREM-1 (FDR <0.001), IP-10 (FDR <0.01), MCP-3 (FDR <0.05), FLT3L (FDR <0.05), Tweak, (FDR <0.05), GRO-α (FDR <0.05), and ENA-78 (FDR <0.05). In univariate studies, analyte overlap between clinical groups prevented clinical relevance. Multivariate models discriminated injury and infection much better, with the 2-group random-forest model classifying 11/11 injury and 28/29 infection patients correctly in out-of-bag validation. CONCLUSIONS: Circulating cytokines in traumatic SIRS differ markedly from those in health or sepsis. Variability limits the accuracy of single-mediator assays but machine learning based on multiplexed plasma assays revealed distinct patterns in sepsis- and injury-related SIRS. Defining biomarker release patterns that distinguish specific SIRS populations might allow decreased antibiotic use in those clinical situations. Large prospective studies are needed to validate and operationalize this approach.


Asunto(s)
Citocinas/sangre , Sepsis/sangre , Sepsis/diagnóstico , Síndrome de Respuesta Inflamatoria Sistémica/sangre , Síndrome de Respuesta Inflamatoria Sistémica/diagnóstico , Informes Anuales como Asunto , Diagnóstico Diferencial , Cirugía General , Pruebas Hematológicas/métodos , Humanos , Estudios Prospectivos , Sepsis/inmunología , Sociedades Médicas , Síndrome de Respuesta Inflamatoria Sistémica/inmunología , Estados Unidos
8.
Am J Psychiatry ; 177(8): 773-786, 2020 08 01.
Artículo en Inglés | MEDLINE | ID: mdl-32741273

RESUMEN

The following are edited/abbreviated versions of the annual reports of the APA Secretary, Treasurer, CEO and Medical Director, Speaker, and Speaker-Elect and the chairpersons of the APA Committee on Bylaws, Membership Committee, Committee of Tellers, and Elections Committee. The full reports were presented at the APA Virtual Spring Highlights Meeting, April 25-26, 2020.


Asunto(s)
Psiquiatría/métodos , Sociedades Médicas/organización & administración , Informes Anuales como Asunto , Miembro de Comité , Congresos como Asunto , Humanos , Innovación Organizacional , Estados Unidos
9.
Br J Nurs ; 29(15): 906-907, 2020 Aug 13.
Artículo en Inglés | MEDLINE | ID: mdl-32790551

RESUMEN

John Tingle, Lecturer in Law, Birmingham Law School, University of Birmingham discusses the recently published Cumberlege report on medicines and medical devices safety.


Asunto(s)
Informes Anuales como Asunto , Seguridad del Paciente , Medicina Estatal/legislación & jurisprudencia , COVID-19 , Infecciones por Coronavirus/epidemiología , Humanos , Pandemias , Neumonía Viral/epidemiología , Reino Unido/epidemiología
10.
Artículo en Inglés | MEDLINE | ID: mdl-32299333

RESUMEN

Australia conducts surveillance for cases of acute flaccid paralysis (AFP) in children less than 15 years as recommended by the World Health Organization (WHO) as the main method to monitor its polio-free status. Cases of AFP in children are notified to the Australian Paediatric Surveillance Unit or the Paediatric Active Enhanced Disease Surveillance System and faecal specimens are referred for virological investigation to the National Enterovirus Reference Laboratory. In 2015, no cases of poliomyelitis were reported from clinical surveillance and Australia reported 1.2 non-polio AFP cases per 100,000 children, meeting the WHO performance criterion for a sensitive surveillance system. Two non-polio enteroviruses, enterovirus A71 and coxsackievirus B3, were identified from clinical specimens collected from AFP cases. Australia complements the clinical surveillance program with enterovirus and environmental surveillance for poliovirus. Two Sabin-like polioviruses were isolated from sewage collected in Melbourne in 2015, which would have been imported from a country that uses the oral polio vaccine. The global eradication of wild poliovirus type 2 was certified in 2015 and Sabin poliovirus type 2 will be withdrawn from oral polio vaccine in April 2016. Laboratory containment of all remaining wild and vaccine strains of poliovirus type 2 will occur in 2016 and the National Enterovirus Reference Laboratory was designated as a polio essential facility. Globally, in 2015, 74 cases of polio were reported, only in the two remaining countries endemic for wild poliovirus: Afghanistan and Pakistan. This is the lowest number reported since the global polio eradication program was initiated.


Asunto(s)
Informes Anuales como Asunto , Notificación de Enfermedades/estadística & datos numéricos , Infecciones por Enterovirus/epidemiología , Vigilancia en Salud Pública , Adolescente , Australia/epidemiología , Niño , Preescolar , Enterovirus/genética , Enterovirus/aislamiento & purificación , Infecciones por Enterovirus/diagnóstico , Infecciones por Enterovirus/virología , Heces/virología , Humanos , Lactante , Paraplejía/diagnóstico , Paraplejía/epidemiología , Paraplejía/virología , Poliovirus , Organización Mundial de la Salud
11.
Artículo en Inglés | MEDLINE | ID: mdl-32299334

RESUMEN

Australia monitors its polio-free status by conducting surveillance for cases of acute flaccid paralysis (AFP) in children less than 15 years of age, as recommended by the World Health Organization (WHO). Cases of AFP in children are notified to the Australian Paediatric Surveillance Unit or the Paediatric Active Enhanced Disease Surveillance System and faecal specimens are referred for virological investigation to the National Enterovirus Reference Laboratory. In 2016, no cases of poliomyelitis were reported from clinical surveillance and Australia reported 1.38 non-polio AFP cases per 100,000 children, meeting the WHO performance criterion for a sensitive surveillance system. Several non-polio enteroviruses, coxsackievirus A6, enterovirus A71, enterovirus A74 and enterovirus D68, were identified from clinical specimens collected from AFP cases. The global withdrawal of Sabin poliovirus type 2 from oral polio vaccine occurred in April 2016. This event represents the start of the polio endgame with an increased focus on the laboratory containment of all remaining wild and vaccine strains of poliovirus type 2. The National Enterovirus Reference Laboratory was designated as a polio essential facility as part of this process. In 2016, 37 cases of wild polio were reported with three countries remaining endemic: Afghanistan, Nigeria and Pakistan. Nigeria was declared polio-free in 2015, after 12 months without detection of wild poliovirus, but was reinstated as an endemic country after the reporting of four cases in August 2016. This is a salient reminder of the need to maintain sensitive surveillance for poliovirus until global eradication is certified.


Asunto(s)
Informes Anuales como Asunto , Notificación de Enfermedades/estadística & datos numéricos , Infecciones por Enterovirus/epidemiología , Vigilancia en Salud Pública , Adolescente , Australia/epidemiología , Niño , Preescolar , Enterovirus/genética , Enterovirus/aislamiento & purificación , Infecciones por Enterovirus/diagnóstico , Infecciones por Enterovirus/virología , Heces/virología , Humanos , Lactante , Paraplejía/diagnóstico , Paraplejía/epidemiología , Paraplejía/virología , Poliovirus , Organización Mundial de la Salud
12.
Artículo en Inglés | MEDLINE | ID: mdl-32299335

RESUMEN

Australia monitors its polio-free status by conducting surveillance for cases of acute flaccid paralysis (AFP) in children less than 15 years of age, as recommended by the World Health Organization (WHO). Cases of AFP in children are notified to the Australian Paediatric Surveillance Unit or the Paediatric Active Enhanced Disease Surveillance System and faecal specimens are referred for virological investigation to the National Enterovirus Reference Laboratory. In 2017, no cases of poliomyelitis were reported from clinical surveillance and Australia reported 1.33 non-polio AFP cases per 100,000 children, meeting the WHO performance criterion for a sensitive surveillance system. Three non-polio enteroviruses, coxsackievirus B1, echovirus 11 and enterovirus A71, were identified from clinical specimens collected from AFP cases. Australia established enterovirus and environmental surveillance systems to complement the clinical system focussed on children and an ambiguous vaccine-derived poliovirus type 2 was isolated from sewage in Melbourne. In 2017, 22 cases of wild polio were reported with three countries remaining endemic: Afghanistan, Nigeria and Pakistan.


Asunto(s)
Informes Anuales como Asunto , Notificación de Enfermedades/estadística & datos numéricos , Infecciones por Enterovirus/epidemiología , Vigilancia en Salud Pública , Adolescente , Australia/epidemiología , Niño , Preescolar , Enterovirus/genética , Enterovirus/aislamiento & purificación , Infecciones por Enterovirus/diagnóstico , Infecciones por Enterovirus/virología , Heces/virología , Humanos , Lactante , Paraplejía/diagnóstico , Paraplejía/epidemiología , Paraplejía/virología , Poliovirus , Organización Mundial de la Salud
13.
Artículo en Inglés | MEDLINE | ID: mdl-32299336

RESUMEN

Australia monitors its polio-free status by conducting surveillance for cases of AFP in children less than 15 years of age, as recommended by the WHO. Cases of AFP in children are notified to the Australian Paediatric Surveillance Unit or the Paediatric Active Enhanced Disease Surveillance System and faecal specimens are referred for virological investigation to the National Enterovirus Reference Laboratory. In 2018, no cases of poliomyelitis were reported from clinical surveillance and Australia reported 1.24 non-polio AFP cases per 100,000 children, meeting the WHO performance criterion for a sensitive surveillance system. Several non-polio enteroviruses, coxsackievirus A4, coxsackievirus B1, echovirus 9, echovirus 30, enterovirus D68 and enterovirus A71, were identified from clinical specimens collected from AFP cases. Australia also performs enterovirus and environmental surveillance to complement the clinical system focussed on children. In 2018, 33 cases of wild polio were reported with three countries remaining endemic: Afghanistan, Nigeria and Pakistan.


Asunto(s)
Informes Anuales como Asunto , Notificación de Enfermedades/estadística & datos numéricos , Infecciones por Enterovirus/epidemiología , Vigilancia en Salud Pública , Adolescente , Australia/epidemiología , Niño , Preescolar , Enterovirus/genética , Enterovirus/aislamiento & purificación , Infecciones por Enterovirus/diagnóstico , Infecciones por Enterovirus/virología , Heces/virología , Humanos , Lactante , Paraplejía/diagnóstico , Paraplejía/epidemiología , Paraplejía/virología , Poliovirus , Organización Mundial de la Salud
14.
Br J Nurs ; 29(4): 250-251, 2020 Feb 27.
Artículo en Inglés | MEDLINE | ID: mdl-32105535

RESUMEN

John Tingle, Lecturer in Law, Birmingham Law School, University of Birmingham, discusses some recent patient reports and crisis events.


Asunto(s)
Informes Anuales como Asunto , Seguridad del Paciente , Medicina Estatal/legislación & jurisprudencia , Comités Consultivos , Femenino , Humanos , Servicios de Salud Materna/normas , Embarazo , Calidad de la Atención de Salud , Medicina Estatal/normas , Reino Unido
16.
Gac. sanit. (Barc., Ed. impr.) ; 34(supl.1): 3-10, ene. 2020. tab, graf
Artículo en Español | IBECS | ID: ibc-201173

RESUMEN

El cambio efectivo de la salud mental en España se inició en 1985 con el Informe de la Comisión Ministerial para la Reforma Psiquiátrica, que recomendaba integrar la asistencia psiquiátrica dentro de sistema sanitario general, proveer una atención integral en el entorno del paciente y atender a grupos diagnósticos específicos. El Informe SESPAS 2002 analizó la reforma y recomendó crear una comisión ministerial permanente, diseñar un mapa nacional de servicios sociosanitarios de salud mental, crear una agencia de coordinación y de promoción de la salud mental, y analizar la financiación de los recursos y la investigación. Desde 2004, el Comité Técnico de la Estrategia de Salud Mental impulsó la elaboración de un marco teórico y normativo que desafortunadamente no se siguió de una hoja de ruta para la mejora del sistema. Después de 2011, el impulso inicial se disipó y el Ministerio de Sanidad declinó liderar la transformación del sistema partiendo de la evidencia informada. Actualmente, el modelo de salud mental comunitaria de 1985 sigue vigente con la adición de algunas mejoras derivadas del modelo de la recuperación (Recovery) y en línea con el modelo del equilibrio de la atención (Balance of care). Asimismo, se ha avanzado en el desarrollo de métodos de evaluación de sistemas y de modelación basada en datos. Sin embargo, la brecha entre la atención general y la de salud mental ha vuelto a aumentar y no se ha avanzado en el desarrollo de una nueva estrategia de salud mental en España


Effective mental health change in Spain started in 1985 with the Report of the Ministerial Commission for the Psychiatric Reform that recommended integrating psychiatric care into the general health system, providing care in the patient's context and for specific diagnoses. The SESPAS 2002 Report carried out an analysis of this reform and recommended the creation of a permanent ministerial commission, the design of a national map of socio-sanitary mental health services, the creation of a coordination and promotion agency for and carrying out a financial analysis of resource provision and research. Since 2004, the Technical Committee for the Mental Health Strategy boosted the elaboration of a theoretical and normative framework that unfortunately did not lead to a road map for the improvement of the system. After 2011, during the financial crisis, the Ministry of Health lost the opportunity to lead a second phase of change of the mental health care, which was evidence-based: no key technical reports were published nor was an action plan based on data developed. Currently, the 1985 community mental health model is still the general framework of mental health care with the addition of aspects related to the recovery model and the balance of care model. Significant progress has been made in developing care systems assessment methods and data-based models that could advance mental health planning. The gap between general health attention and mental health care has increased and the expected reform of the mental health system will not take place in the near future


Asunto(s)
Humanos , Atención a la Salud Mental , Trastornos Mentales/epidemiología , Servicios de Salud Mental/organización & administración , 50207 , Pautas de la Práctica en Medicina/tendencias , Informes Anuales como Asunto , Medicina Basada en la Evidencia/tendencias , Apoyo a la Planificación en Salud/tendencias , Estrategias de Salud Nacionales , España/epidemiología
17.
Gac. sanit. (Barc., Ed. impr.) ; 34(supl.1): 20-26, ene. 2020. tab, graf
Artículo en Español | IBECS | ID: ibc-201175

RESUMEN

En atención primaria solo el dolor crónico supera a la depresión y la ansiedad en la pérdida de años de vida ajustados por calidad. Más del 70% de las personas que sufrían enfermedades mentales comunes consultaron por ello a su médico/a de familia. Sin embargo, «la regla de las mitades decrecientes» es una realidad: menos del 50% de las personas consultantes de atención primaria con enfermedades mentales comunes fueron diagnosticadas correctamente, y de ellas, menos del 50% recibieron un tratamiento (farmacológico o psicológico) adecuado, y de estas, menos del 50% fueron adherentes. Los modelos colaborativos de atención a las enfermedades mentales comunes en atención primaria han demostrado su efectividad en ensayos clínicos, pero su implementación en un contexto más general y real es difícil y su efectividad todavía es poco conocida. Se han desarrollado y validado algoritmos de riesgo para predecir el inicio y el pronóstico de las enfermedades mentales comunes en atención primaria que son útiles para su tratamiento y prevención. Existen evidencias de que las intervenciones psicológicas, psicoeducativas y de ejercicio físico son efectivas en prevención primaria, incluso en atención primaria, aunque su efecto es pequeño o moderado. Estas intervenciones tienen un gran potencial para ser escalables en las escuelas, el ámbito laboral y la atención primaria; además, cuando se administran mediante tecnologías de la información y la comunicación (p. ej., App), en programas autoguiados o mínimamente guiados, han demostrado su efectividad para el tratamiento y la prevención de las enfermedades mentales comunes. También son muy accesibles y de bajo coste, y contribuyen a la implementación masiva de estas intervenciones en diferentes contextos


In primary health care only chronic pain surpass depression and anxiety in loss of quality-adjusted life years. More than 70% of people suffering from common mental disorders consulted their GPs for this reason. However, 'the declining halves rule' is a reality: less than 50% of primary care attendees with common mental disorders were correctly diagnosed, of these less than 50% received adequate treatment (pharmacological or psychological) and of these less than 50% patients were adherent. Collaborative models of common mental disorders care in primary health care have demonstrated their effectiveness through clinical trials; however, its implementation in a more general and real context is difficult and its effectiveness remains unclear. Risk algorithms have been developed and validated in primary health care to predict the onset and prognosis of common mental disorders; which are useful for their treatment and prevention. There is evidence that psychological and psychoeducational interventions (and possibly those of physical exercise) are effective for the primary prevention of common mental disorders, even in primary health care; although their effects are small or moderate. These interventions have a high potential to be scalable in schools, workplace and primary health care; in addition, when they are administered through information and communication technologies (e.g. by App), in self-guided or minimally guided programs, they have demonstrated their effectiveness for the treatment and prevention of common mental disorders. They are also very accessible, have low cost and contribute to the massive implementation of these interventions in different settings


Asunto(s)
Humanos , Salud Mental/tendencias , Trastornos Mentales/epidemiología , 50207 , Barreras de Acceso a los Servicios de Salud/tendencias , Trastornos de Ansiedad/epidemiología , Trastorno Depresivo/epidemiología , Informes Anuales como Asunto , Gradiente Socioeconómico de Salud/tendencias , Disparidades en el Estado de Salud , Trastornos Mentales/prevención & control , Atención Primaria de Salud/organización & administración , Prevención Primaria/organización & administración , España/epidemiología
18.
J Obstet Gynaecol Res ; 46(1): 39-48, 2020 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-31595599

RESUMEN

Since 2010, the Women's Health Care Committee has continuously addressed issues closely linked to women's quality of life. The five agendas this committee has engaged for this academic year are as follows: (i) clinical study of urinary complications in perinatal and post-partum women's health care; (ii) enlightenment of infectious diseases in Obstetrics and Gynecology in Japan; (iii) educational activities regarding management guidelines for health care in female athletes; (iv) training program for women's health-care advisers; and (v) pregnancy- and lactation-associated osteoporosis (PLOP). The detailed activities of the five subcommittees are described herein. This report is based on the Japanese version of our annual report (Acta Obst Gynaec Jpn 2019;71(6): 889-898), which publicizes the activities of our committee.


Asunto(s)
Informes Anuales como Asunto , Ginecología/organización & administración , Obstetricia/organización & administración , Sociedades Médicas/organización & administración , Salud de la Mujer/tendencias , Femenino , Ginecología/tendencias , Humanos , Japón , Obstetricia/tendencias , Embarazo
19.
Lima; Organismo Andino de Salud Convenio Hipólito Unanue; primera; 2020. 76 p.
No convencional en Español | LILACS, LIPECS | ID: biblio-1102481

RESUMEN

El presente Informe de Gestión 2016 ­ 2020 del ORAS - CONHU tiene la intención de mostrar la coherencia institucional hacia los principios del Convenio y la fortaleza de los seis Ministerios de Salud para arribar a logros conjuntos. El contenido hace un recorrido rápido de la historia, los principios y normas que conducen la vida del ORAS-CONHU.


Asunto(s)
Control Sanitario de Fronteras , Informes Anuales como Asunto
20.
Clin Toxicol (Phila) ; 57(12): 1220-1413, 2019 12.
Artículo en Inglés | MEDLINE | ID: mdl-31752545

RESUMEN

Introduction: This is the 36th Annual Report of the American Association of Poison Control Centers' (AAPCC) National Poison Data System (NPDS). As of 1 January, 2018, 55 of the nation's poison centers (PCs) uploaded case data automatically to NPDS. The upload interval was 7.72 [6.90, 12.0] (median [25%, 75%]) minutes, creating a near real-time national exposure and information database and surveillance system.Methods: We analyzed the case data tabulating specific indices from NPDS. The methodology was similar to that of previous years. Where changes were introduced, the differences are identified. Cases with medical outcomes of death were evaluated by a team of medical and clinical toxicologist reviewers using an ordinal scale of 1-6 to assess the Relative Contribution to Fatality (RCF) of the exposure.Results: In 2018, 2,530,238 closed encounters were logged by NPDS: 2,099,751 human exposures, 57,017 animal exposures, 368,025 information requests, 5,346 human confirmed nonexposures, and 99 animal confirmed nonexposures. United States PCs also made 2,621,242 follow-up calls in 2018. Total encounters showed a 2.96% decline from 2017, while health care facility (HCF) human exposure cases remained nearly steady with a slight decrease of 0.261%. All information requests decreased by 15.5%, medication identification (Drug ID) requests decreased by 30.2%, and human exposure cases decreased by 0.729%. Human exposures with less serious outcomes have decreased 2.33% per year since 2008, while those with more serious outcomes (moderate, major or death) have increased 4.45% per year since 2000.Consistent with the previous year, the top 5 substance classes most frequently involved in all human exposures were analgesics (10.8%), household cleaning substances (7.28%), cosmetics/personal care products (6.53%), sedatives/hypnotics/antipsychotics (5.53%), and antidepressants (5.22%). For cases with more serious outcomes, sedative/hypnotics/antipsychotics exposures were the class that increased most rapidly, by 1,828 cases/year (9.21%/year) over the past 18 years. Over just the past 10 years (for cases with the most serious outcomes) antidepressant exposures increased most rapidly, by 1,887 cases/year (7.02%/year).The top 5 most common exposures in children age 5 years or less were cosmetics/personal care products (12.1%), household cleaning substances (10.7%), analgesics (9.04%), foreign bodies/toys/miscellaneous (6.87%), and topical preparations (4.69%). Drug identification requests comprised 18.2% of all information requests. NPDS documented 3,111 human exposures resulting in death; 2,582 (83.0%) of these were judged as related (RCF of 1-Undoubtedly responsible, 2-Probably responsible, or 3-Contributory).Conclusions: These data support the continued value of PC expertise and need for specialized medical toxicology information to manage more serious exposures. Unintentional and intentional exposures continue to be a significant cause of morbidity and mortality in the US. The near real-time status of NPDS represents a national public health resource to collect and monitor US exposure cases and information requests. The continuing mission of NPDS is to provide a nationwide infrastructure for surveillance for all types of exposures (e.g., foreign body, infectious, venomous, chemical agent, or commercial product), and the identification and tracking of significant public health events. NPDS is a model system for the near real-time surveillance of national and global public health.


Asunto(s)
Exposición a Riesgos Ambientales/estadística & datos numéricos , Centros de Control de Intoxicaciones/estadística & datos numéricos , Envenenamiento/epidemiología , Animales , Informes Anuales como Asunto , Bases de Datos Factuales , Exposición a Riesgos Ambientales/efectos adversos , Humanos , Estados Unidos/epidemiología
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