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2.
J Nurs Adm ; 51(5): 240-241, 2021 May 01.
Artículo en Inglés | MEDLINE | ID: mdl-33882550

RESUMEN

Strategies used to change an annual statewide research symposium from a face-to-face experience to a virtual event at a 434-bed Magnet® redesignated community hospital are described. The program met with success and increased access for attendees. For the 1st time, credited to the virtual format, representatives from all 9 hospitals in the system were able to attend. Feedback following the symposium suggested that participants who live at a distance from the hospital appreciated being able to attend the meeting without traveling, technical issues were promptly resolved, and presenters received positive evaluations.


Asunto(s)
Congresos como Asunto/organización & administración , Educación a Distancia/organización & administración , Realidad Virtual , Investigación Biomédica/organización & administración , Humanos , Interfaz Usuario-Computador
3.
PLoS One ; 16(4): e0249280, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33793613

RESUMEN

International scientific collaborations have always been regarded as critical actions to address global pandemics, however, there was an obvious uncertainty between international collaboration and the COVID-19 control. We aim to combine digital data-based strategies to produce meaningful and advanced insights into the imbalance between COVID-19 and international collaboration, as well as reveal possible influencing factors, and ultimately enhance global collaboration. We conducted three retrospective cohort studies using respectively COVID-19 data from WHO, a complete dataset of scientific publications on coronavirus-related research from WoS, and daily data from Google Trends (GT). The results of geovisualization and spatiotemporal analysis revealed that the global COVID19 pandemic still remains serious. The global issue of imbalance between international collaborations and pandemic does exit, and the nations with good pandemic control had their own characteristics in above-mentioned correlation. Digital epidemiology provides, at least in part, evidence-based assessment and scientific advice to understand the imbalance between international collaborations and COVID-19. Our investigation demonstrates that transdisciplinary conversation through digital data-based strategies can help us fully understand the complex factors influencing the effectiveness of international scientific collaboration, thus facilitating the global response to COVID-19.


Asunto(s)
Investigación Biomédica , Manejo de Datos , Cooperación Internacional , Pandemias/estadística & datos numéricos , Investigación Biomédica/organización & administración , Investigación Biomédica/estadística & datos numéricos , Humanos , Colaboración Intersectorial , Estudios Retrospectivos
5.
Mol Cell ; 81(5): 885-888, 2021 03 04.
Artículo en Inglés | MEDLINE | ID: mdl-33667376

RESUMEN

As part of our commitment to amplifying the voices of underrepresented scientists, we are publishing the insights and experiences of a panel of underrepresented scientists. In this segment, we asked about support systems-the types of support that are most helpful (and less helpful), how to find a supportive network, and how institutions can better support underrepresented scientists. These are the personal opinions of the authors and may not reflect the views of their institutions.


Asunto(s)
Investigación Biomédica/ética , Grupos Minoritarios/psicología , Investigadores/psicología , Adulto , Investigación Biomédica/organización & administración , Diversidad Cultural , Femenino , Humanos , Masculino , Relaciones Raciales/psicología , Apoyo Social , Estados Unidos
6.
Mol Cell ; 81(5): 889-892, 2021 03 04.
Artículo en Inglés | MEDLINE | ID: mdl-33667377

RESUMEN

We talk to Prashant Rawat and Marc Boehning, collaborators and co-first authors of "Stress-induced nuclear condensation of NELF drives global transcriptional downregulation" (this issue, previewed by Xu et al.), about their motivation for becoming scientists, the challenges they faced in the course of their project, and the importance of collaboration for scientific research.


Asunto(s)
Investigación Biomédica/organización & administración , Selección de Profesión , Mentores/educación , Transcripción Genética , Adulto , Alemania , Historia del Siglo XXI , Humanos , Masculino
7.
Mol Cell ; 81(5): 893-895, 2021 03 04.
Artículo en Inglés | MEDLINE | ID: mdl-33667378

RESUMEN

Here, we talk to first authors Kyosuke Nakamura and Georg Kustatscher, as well as co-corresponding author Anja Groth, about their paper "Proteome dynamics at broken replication forks reveal a distinct ATM-directed repair response suppressing double-strand break ubiquitination" (in this issue of Molecular Cell) and their scientific journeys until now.


Asunto(s)
Investigación Biomédica/organización & administración , Selección de Profesión , Replicación del ADN , Proteómica/tendencias , Adulto , Dinamarca , Historia del Siglo XXI , Humanos , Masculino , Mentores
8.
J Altern Complement Med ; 27(S1): S7-S13, 2021 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-33788600

RESUMEN

Published results of efficacy and effectiveness studies on complementary health approaches should lead to widespread uptake of evidence-based practices, but too often, the scientific pathway ends prematurely, before the best ways to improve adoption, implementation, and sustainability can be determined. The National Center for Complementary and Integrative Health (NCCIH) supports the full continuum of the biomedical research pipeline, whereby a complementary health intervention moves from basic and mechanistic research through efficacy trials and through dissemination and implementation. Implementation science has traditionally been thought of as something that only happens after efficacy and effectiveness have been demonstrated, but it can be prudent to evaluate implementation measures earlier in the process. Implementation science assesses more than just barriers and facilitators; it evaluates specific implementation strategies and characterizes the extent that the intervention is modified within the context of the implementation strategy and health care delivery setting. The best choices for implementation science in complementary health interventions depend on the research questions. Implementation science that tests strategies to address implementation at multiple ecologic levels is a high priority to NCCIH.


Asunto(s)
Investigación Biomédica , Terapias Complementarias/organización & administración , Ciencia de la Implementación , Medicina Integral/organización & administración , Investigación Biomédica/métodos , Investigación Biomédica/organización & administración , Humanos , Modelos Organizacionales
12.
Proc Natl Acad Sci U S A ; 118(6)2021 02 09.
Artículo en Inglés | MEDLINE | ID: mdl-33531366

RESUMEN

With more time being spent on caregiving responsibilities during the COVID-19 pandemic, female scientists' productivity dropped. When female scientists conduct research, identity factors are better incorporated in research content. In order to mitigate damage to the research enterprise, funding agencies can play a role by putting in place gender equity policies that support all applicants and ensure research quality. A national health research funder implemented gender policy changes that included extending deadlines and factoring sex and gender into COVID-19 grant requirements. Following these changes, the funder received more applications from female scientists, awarded a greater proportion of grants to female compared to male scientists, and received and funded more grant applications that considered sex and gender in the content of COVID-19 research. Further work is urgently required to address inequities associated with identity characteristics beyond gender.


Asunto(s)
/epidemiología , Equidad de Género , Políticas , Investigadores/estadística & datos numéricos , Distinciones y Premios , Investigación Biomédica/economía , Investigación Biomédica/organización & administración , Eficiencia , Femenino , Organización de la Financiación/estadística & datos numéricos , Humanos , Masculino , Pandemias , Investigadores/economía , Factores Sexuales
13.
Clin Trials ; 18(2): 226-233, 2021 04.
Artículo en Inglés | MEDLINE | ID: mdl-33530721

RESUMEN

Given the dearth of established safe and effective interventions to respond to COVID-19, there is an urgent ethical imperative to conduct meaningful clinical research. The good news is that interventions to be tested are not in short supply. Unfortunately, the human and material resources needed to conduct these trials are finite. It is essential that trials be robust and meet enrollment targets and that lower-quality studies not be permitted to displace higher-quality studies, delaying answers to critical questions. Yet, with few exceptions, existing research review bodies and processes are not designed to ensure these conditions are satisfied. To meet this challenge, we offer guidance for research institutions about how to ethically consolidate and prioritize COVID-19 clinical trials, while recognizing that consolidation and prioritization should also take place upstream (among manufacturers and funders) and at a higher level (e.g. nationally). In our proposed three-stage process, trials must first meet threshold criteria. Those that do are evaluated in a second stage to determine whether the institution has sufficient capacity to support all proposed trials. If it does not, the third stage entails evaluating studies against two additional sets of comparative prioritization criteria: those specific to the study and those that aim to advance diversification of an institution's research portfolio. To implement these criteria fairly, we propose that research institutions form COVID-19 research prioritization committees. We briefly discuss some important attributes of these committees, drawing on the authors' experiences at our respective institutions. Although we focus on clinical trials of COVID-19 therapeutics, our guidance should prove useful for other kinds of COVID-19 research, as well as non-pandemic research, which can raise similar challenges due to the scarcity of research resources.


Asunto(s)
/terapia , Ensayos Clínicos como Asunto/ética , Ensayos Clínicos como Asunto/organización & administración , Investigación Biomédica/ética , Investigación Biomédica/organización & administración , Comités de Ética en Investigación , Ética en Investigación , Prioridades en Salud , Recursos en Salud , Humanos , Proyectos de Investigación
20.
J Cell Biol ; 220(2)2021 02 01.
Artículo en Inglés | MEDLINE | ID: mdl-33475700

RESUMEN

JCB checks in with newly independent cell biologists and learns about their experience running a lab during the COVID-19 pandemic.


Asunto(s)
Investigación Biomédica , Laboratorios , Pandemias , Investigadores , Investigación Biomédica/organización & administración , Humanos , Laboratorios/organización & administración
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