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1.
Artif Intell Med ; 114: 102053, 2021 04.
Artículo en Inglés | MEDLINE | ID: mdl-33875160

RESUMEN

MOTIVATION: In the age of big data, the amount of scientific information available online dwarfs the ability of current tools to support researchers in locating and securing access to the necessary materials. Well-structured open data and the smart systems that make the appropriate use of it are invaluable and can help health researchers and professionals to find the appropriate information by, e.g., configuring the monitoring of information or refining a specific query on a disease. METHODS: We present an automated text classifier approach based on the MEDLINE/MeSH thesaurus, trained on the manual annotation of more than 26 million expert-annotated scientific abstracts. The classifier was developed tailor-fit to the public health and health research domain experts, in the light of their specific challenges and needs. We have applied the proposed methodology on three specific health domains: the Coronavirus, Mental Health and Diabetes, considering the pertinence of the first, and the known relations with the other two health topics. RESULTS: A classifier is trained on the MEDLINE dataset that can automatically annotate text, such as scientific articles, news articles or medical reports with relevant concepts from the MeSH thesaurus. CONCLUSIONS: The proposed text classifier shows promising results in the evaluation of health-related news. The application of the developed classifier enables the exploration of news and extraction of health-related insights, based on the MeSH thesaurus, through a similar workflow as in the usage of PubMed, with which most health researchers are familiar.


Asunto(s)
Comunicación en Salud/normas , MEDLINE/organización & administración , Medical Subject Headings , Investigación/organización & administración , Macrodatos , Clasificación , Diabetes Mellitus/epidemiología , Humanos , MEDLINE/normas , Salud Mental/estadística & datos numéricos , Semántica
2.
Lancet ; 397(10280): 1229-1236, 2021 03 27.
Artículo en Inglés | MEDLINE | ID: mdl-33711296

RESUMEN

The research and development (R&D) ecosystem has evolved over the past decade to include pandemic infectious diseases, building on experience from multiple recent outbreaks. Outcomes of this evolution have been particularly evident during the COVID-19 pandemic with accelerated development of vaccines and monoclonal antibodies, as well as novel clinical trial designs. These products were developed, trialled, manufactured, and authorised for use in several countries within a year of the pandemic's onset. Many gaps remain, however, that must be bridged to establish a truly efficient and effective end-to-end R&D preparedness and response ecosystem. Foremost among them is a global financing system. In addition, important changes are required for multiple aspects of enabling sciences and product development. For each of these elements we identify priorities for improved and faster functionality. There will be no better time than now to seriously address these needs, however difficult, as the ravages of COVID-19 continue to accelerate with devastating health, social, and economic consequences for the entire community of nations.


Asunto(s)
Salud Global , Cooperación Internacional , Pandemias/prevención & control , Investigación/economía , Investigación/organización & administración , Humanos , Modelos Organizacionales
5.
Microbiome ; 9(1): 36, 2021 02 01.
Artículo en Inglés | MEDLINE | ID: mdl-33522965

RESUMEN

In the past decade, there has been increasing interest in mosquito microbiome research, leading to large amounts of data on different mosquito species, with various underlying physiological characteristics, and from diverse geographical locations. However, guidelines and standardized methods for conducting mosquito microbiome research are lacking. To streamline methods in mosquito microbiome research and optimize data quality, reproducibility, and comparability, as well as facilitate data curation in a centralized location, we are establishing the Mosquito Microbiome Consortium, a collaborative initiative for the advancement of mosquito microbiome research. Our overall goal is to collectively work on unraveling the role of the mosquito microbiome in mosquito biology, while critically evaluating its potential for mosquito-borne disease control. This perspective serves to introduce the consortium and invite broader participation. It highlights the issues we view as most pressing to the community and proposes guidelines for conducting mosquito microbiome research. We focus on four broad areas in this piece: (1) sampling/experimental design for field, semi-field, or laboratory studies; (2) metadata collection; (3) sample processing, sequencing, and use of appropriate controls; and (4) data handling and analysis. We finally summarize current challenges and highlight future directions in mosquito microbiome research. We hope that this piece will spark discussions around this area of disease vector biology, as well as encourage careful considerations in the design and implementation of mosquito microbiome research. Video Abstract.


Asunto(s)
Culicidae/microbiología , Metagenómica , Microbiota , Investigación/organización & administración , Investigación/tendencias , Animales , Reproducibilidad de los Resultados
7.
Midwifery ; 95: 102922, 2021 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-33515973

RESUMEN

The purpose of this project was to identify gaps in the current evidence base and to identify research priorities in the local context during the Covid-19 pandemic. This paper reports on the application and adaptation of the CHNRI methodology which follows a series of criteria setting, filtering and scoring exercises. The views of maternity care professionals, midwifery managers and leaders, women and families were continually sought throughout the project stages. We found the CHNRI methodology to be a useful framework to highlight topics with greater or smaller consensus within a relatively short time frame and with minimal burden to participants. The criteria were defined to focus on research topics where no existing or on-going studies were identified and topics likely to lead to improvements in care with relevance beyond the Covid-19 pandemic.


Asunto(s)
Investigación sobre Servicios de Salud/organización & administración , Servicios de Salud Materna , Partería , Proyectos de Investigación , Investigación/organización & administración , Consenso , Femenino , Humanos , Embarazo , Reino Unido
8.
Chem Res Toxicol ; 34(3): 672-674, 2021 03 15.
Artículo en Inglés | MEDLINE | ID: mdl-33355440

RESUMEN

As COVID-19 swept across the world, it created a global pandemic and an unpredictable and challenging job market. This article discusses the future of the 2020-2021 job market in both academia and industry in the midst and aftermath of this pandemic.


Asunto(s)
Biofarmacia/economía , Industria Química/economía , Universidades/economía , Biofarmacia/organización & administración , Biofarmacia/tendencias , Industria Química/organización & administración , Humanos , Pandemias , Investigación/economía , Investigación/organización & administración , Red Social , Desempleo , Universidades/organización & administración , Recursos Humanos
9.
Acad Med ; 96(3): 340-342, 2021 03 01.
Artículo en Inglés | MEDLINE | ID: mdl-33332910

RESUMEN

During the COVID-19 pandemic, there has been a global shift toward online distance learning due to travel limitations and physical distancing requirements as well as medical school and university closures. In low- and middle-income countries like Nepal, where medical education faces a range of challenges-such as lack of infrastructure, well-trained educators, and advanced technologies-the abrupt changes in methodologies without adequate preparation are more challenging than in higher-income countries. In this article, the authors discuss the COVID-19-related changes and challenges in Nepal that may have a drastic impact on the career progression of current medical students. Outside the major cities, Nepal lacks dependable Internet services to support medical education, which frequently requires access to and transmission of large files and audiovisual material. Thus, students who are poor, who are physically disadvantaged, and who do not have a home situation conducive to online study may be affected disproportionately. Further, the majority of teachers and students do not have sufficient logistical experience and knowledge to conduct or participate in online classes. Moreover, students and teachers are unsatisfied with the digital methodologies, which will ultimately hamper the quality of education. Students' clinical skills development, research activities, and live and intimate interactions with other individuals are being affected. Even though Nepal's medical education system is struggling to adapt to the transformation of teaching methodologies in the wake of the pandemic, it is important not to postpone the education of current medical students and future physicians during this crisis. Looking ahead, medical schools in Nepal should ensure that mechanisms are proactively put into place to embrace new educational opportunities and technologies to guarantee a regular supply of high-quality physicians capable of both responding effectively to any future pandemic and satisfying the nation's future health care needs.


Asunto(s)
/epidemiología , Países en Desarrollo , Educación Médica/organización & administración , Competencia Clínica , Educación a Distancia/organización & administración , Educación a Distancia/tendencias , Educación Médica/tendencias , Predicción , Necesidades y Demandas de Servicios de Salud/organización & administración , Necesidades y Demandas de Servicios de Salud/tendencias , Humanos , Desarrollo Industrial/tendencias , Nepal , Investigación/organización & administración , Investigación/tendencias , Enseñanza/organización & administración , Enseñanza/tendencias
19.
Hist Philos Life Sci ; 42(4): 53, 2020 Nov 03.
Artículo en Inglés | MEDLINE | ID: mdl-33141370

RESUMEN

The SARS-CoV-2 pandemic constituted a crisis situation in which science was very far from Kitcher's ideal of well-ordered science. I suggest that this could and should have been different. Kitcher's ideal should play a role in assessing the allocation of research resources in future crisis situations, as it provides a way to balance highly divergent interests and incorporate the common good into decision-making processes on research.


Asunto(s)
Infecciones por Coronavirus/prevención & control , Pandemias/prevención & control , Neumonía Viral/prevención & control , Proyectos de Investigación , Investigación/organización & administración , Betacoronavirus/fisiología , Infecciones por Coronavirus/epidemiología , Humanos , Neumonía Viral/epidemiología
20.
Metas enferm ; 23(9): 15-21, nov. 2020. tab
Artículo en Español | IBECS | ID: ibc-197935

RESUMEN

Este artículo presenta la composición, líneas de investigación y evolución del grupo de investigación enfermera (GRIN) vinculado al Instituto de Investigación Biomédica de Bellvitge (IDIBELL). Las líneas principales de investigación van dirigidas a la prestación de cuidados enfermeros y su impacto en los resultados de salud de los pacientes y familias, orientándose principalmente en la investigación en cuidados a poblaciones vulnerables, enfermos críticos, pacientes crónicos complejos y personas en extremos de edad, en las siguientes áreas de interés: i) promoción de la salud; ii) innovaciones tecnológicas, sistemas de información e inteligencia artificial para la salud; iii) desarrollo metodológico, ético y social de los cuidados; iv) gestión de cuidados y resultados sensibles a la práctica enfermera; v) cribado, detección precoz y prevención de complicaciones y discapacidades. Actualmente el grupo está formado por 33 enfermeras/os, que pertenecen a cuatro hospitales y la Universidad de Barcelona, siendo el 48% doctores y el 36% doctorandos. El grupo ha producido más de 150 publicaciones científicas en siete años, de las cuales, durante el último año, el 50% fue en Q1 y el 20% en Q2, además destacando que el 60% de los proyectos obtuvo algún tipo de financiación durante el último año. El grupo de investigación está acreditado como grupo preconsolidado por la Agencia de Gestión de Ayudas Universitarias y de Investigación (AGAUR) de la Generalitat de Cataluña


This article presents the composition, lines of research and evolution of the nursing research group (GRIN) linked to the Bellvitge Institute for Biomedical Research (IDIBELL). The main lines of research are targeted to the provision of nursing care and its impact on health outcomes for patients and relatives; it is particularly oriented towards research in care for vulnerable populations, critical patients, complex chronic patients, and people with extreme ages, within the following areas of interest: i) health promotion; ii) technological innovations, information systems and artificial intelligence for health; iii) methodological, ethical and social development of care; iv) management of care and nursing-sensitive outcomes; v) screening, early detection and prevention of complications and disabilities. Currently, the group is formed by 33 nurses from four hospitals and the University of Barcelona; 48% of its members are doctors and 36% are doctoral candidates. The group has published over 150 scientific articles in seven years; during the last year, 50% of these were in Q1 and 20% in Q2. It should also be highlighted that 60% of projects obtained some type of funding during the past year. The research group is accredited as a preconsolidated group by the Agency for Management of University and Research Grants (AGAUR) of the Generalitat of Catalonia


Asunto(s)
Humanos , Investigación/organización & administración , Investigación/normas , Investigación en Enfermería/organización & administración , Atención de Enfermería , Enfermería Práctica/organización & administración , Investigación en Enfermería/normas , Enfermería Práctica/normas
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