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1.
Anticancer Res ; 41(4): 1971-1974, 2021 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-33813403

RESUMEN

BACKGROUND/AIM: Oncological care has faced several challenges during the COVID-19 pandemic, e.g. treatment delay and worsening symptoms. Patient-reported anxiety, depression and sleep quality might have changed due to these special circumstances. Therefore, we analyzed the symptom burden of patients treated with palliative radiotherapy at our center. PATIENTS AND METHODS: A retrospective study was performed of 50 consecutive patients and the results were compared to those obtained in a previous pre-COVID study. The Edmonton Symptom Assessment Scale was employed to assess the preradiotherapy symptoms. RESULTS: The highest mean scores were reported for pain in activity (3.2) and dry mouth (3.1). Regarding anxiety, sadness/depression and sleep, the corresponding scores were 1.5, 1.2 and 2.7, respectively. Compared to the previous study, no significant increases were found. Most items had numerically lower mean values, e.g. anxiety (1.5 vs. 2.7). Both study populations had comparable median age (70.5 vs. 70 years), gender distribution and proportion of patients with bone metastases. However, there were two significant imbalances, namely a lower proportion of patients with prostate cancer (12 vs. 30%, p=0.02) and breast cancer (0 vs. 12%, p=0.02). CONCLUSION: In patients who showed up for radiation treatment planning, the suspected increase in anxiety, sadness/depression and sleep disturbance was not demonstrable. It is not known whether or not patients with substantial worries chose to decline referral to palliative radiotherapy. Therefore, comprehensive large-scale studies of patterns of care are needed to fully understand the impact of COVID-19-related measures.


Asunto(s)
/epidemiología , Costo de Enfermedad , Neoplasias/radioterapia , Cuidados Paliativos/métodos , Pandemias , Anciano , Anciano de 80 o más Años , Ansiedad/epidemiología , Ansiedad/etiología , Neoplasias Óseas/epidemiología , Neoplasias Óseas/secundario , Dolor en Cáncer/diagnóstico , Dolor en Cáncer/epidemiología , Dolor en Cáncer/etiología , Depresión/epidemiología , Depresión/etiología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Neoplasias/complicaciones , Neoplasias/epidemiología , Neoplasias/patología , Noruega/epidemiología , Estudios Retrospectivos , Análisis de Supervivencia , Evaluación de Síntomas
2.
Artículo en Inglés | MEDLINE | ID: mdl-33805097

RESUMEN

The COVID-19 pandemic may be of particular concern for pregnant and breastfeeding women. We aimed to explore their beliefs about the coronavirus and COVID-19 vaccine willingness and to assess the impact of the pandemic on perinatal experiences and practices. A multinational, cross-sectional, web-based study was performed in six European countries between April and July 2020. The anonymous survey was promoted via social media. In total, 16,063 women participated (including 6661 pregnant and 9402 breastfeeding women). Most responses were collected from Belgium (44%), Norway (18%) and the Netherlands (16%), followed by Switzerland (11%), Ireland (10%) and the UK (3%). Despite differences between countries, COVID-19 vaccine hesitancy was identified among 40-50% of the respondents at the end of the first wave of the pandemic and was higher among pregnant women. Education level and employment status were associated with vaccine hesitancy. The first wave had an adverse impact on pregnancy experiences and disrupted access to health services and breastfeeding support for many women. In the future, access to health care and support should be maintained at all times. Evidence-based and tailored information on COVID-19 vaccines should also be provided to pregnant and breastfeeding women to avoid unfounded concerns about the vaccines and to support shared decision making in this population.


Asunto(s)
Pandemias , Bélgica , Estudios Transversales , Europa (Continente) , Femenino , Humanos , Irlanda , Países Bajos , Noruega , Pandemias/prevención & control , Embarazo , Suiza
3.
Artículo en Inglés | MEDLINE | ID: mdl-33799497

RESUMEN

COVID-19 has been a global healthcare concern impacting multiple aspects of individual and community wellness. As one moves forward with different methods to reduce the infection and mortality rates, it is critical to continue to study the impact that national and local "social distancing" policies have on the daily lives of individuals. The aim of this study was to examine loneliness in relation to risk assessment, measures taken against risks, concerns, and social media use, while adjusting for sociodemographic variables. The cross-sectional study collected data from 3474 individuals from the USA, the UK, Norway, and Australia. Loneliness was measured with the de Jong Gierveld Loneliness Scale. Multiple linear regression was used in the analysis of associations between variables. The results showed that concerns about finances were more strongly associated with social loneliness, while concerns about the future was more strongly associated with emotional loneliness. Longer daily time spent on social media was associated with higher emotional loneliness. In conclusion, pandemic-related concerns seem to affect perceptions of loneliness. While social media can be used productively to maintain relationships, and thereby prevent loneliness, excessive use may be counterproductive.


Asunto(s)
Soledad , Australia/epidemiología , Estudios Transversales , Factor IX , Humanos , Noruega/epidemiología
4.
BMJ Open ; 11(3): e043887, 2021 03 10.
Artículo en Inglés | MEDLINE | ID: mdl-33692181

RESUMEN

INTRODUCTION: Very little is known about possible clinical sequelae that may persist after resolution of acute COVID-19. A recent longitudinal cohort from Italy including 143 patients followed up after hospitalisation with COVID-19 reported that 87% had at least one ongoing symptom at 60-day follow-up. Early indications suggest that patients with COVID-19 may need even more psychological support than typical intensive care unit patients. The assessment of risk factors for longer term consequences requires a longitudinal study linked to data on pre-existing conditions and care received during the acute phase of illness. The primary aim of this study is to characterise physical and psychosocial sequelae in patients post-COVID-19 hospital discharge. METHODS AND ANALYSIS: This is an international open-access prospective, observational multisite study. This protocol is linked with the International Severe Acute Respiratory and emerging Infection Consortium (ISARIC) and the WHO's Clinical Characterisation Protocol, which includes patients with suspected or confirmed COVID-19 during hospitalisation. This protocol will follow-up a subset of patients with confirmed COVID-19 using standardised surveys to measure longer term physical and psychosocial sequelae. The data will be linked with the acute phase data. Statistical analyses will be undertaken to characterise groups most likely to be affected by sequelae of COVID-19. The open-access follow-up survey can be used as a data collection tool by other follow-up studies, to facilitate data harmonisation and to identify subsets of patients for further in-depth follow-up. The outcomes of this study will inform strategies to prevent long-term consequences; inform clinical management, interventional studies, rehabilitation and public health management to reduce overall morbidity; and improve long-term outcomes of COVID-19. ETHICS AND DISSEMINATION: The protocol and survey are open access to enable low-resourced sites to join the study to facilitate global standardised, longitudinal data collection. Ethical approval has been given by sites in Colombia, Ghana, Italy, Norway, Russia, the UK and South Africa. New sites are welcome to join this collaborative study at any time. Sites interested in adopting the protocol as it is or in an adapted version are responsible for ensuring that local sponsorship and ethical approvals in place as appropriate. The tools are available on the ISARIC website (www.isaric.org). PROTOCOL REGISTRATION NUMBER: osf.io/c5rw3/ PROTOCOL VERSION: 3 August 2020 EUROQOL ID: 37035.


Asunto(s)
/diagnóstico , /psicología , Colombia , Ghana , Humanos , Italia , Estudios Longitudinales , Noruega , Estudios Prospectivos , Factores de Riesgo , Federación de Rusia , Sudáfrica , Reino Unido
6.
Dis Aquat Organ ; 144: 61-73, 2021 Mar 25.
Artículo en Inglés | MEDLINE | ID: mdl-33764314

RESUMEN

Currently, the prevalence of salmonid alphavirus (SAV) in Norwegian Atlantic salmon farms is largely surveyed via sacrificing fish and sampling of organ tissue on a monthly basis. However, a more cost-efficient, straightforward, rapid, reliable, reproducible and animal welfare friendly method based on the detection of SAV in water could be considered as an alternative method. In the present study, such a method was developed and optimized through a 6 wk cohabitant challenge trial, using post-smolt Atlantic salmon Salmo salar L challenged with high or low doses of SAV subtype 3 (SAV3). Tank water and tissue samples from cohabitant fish were collected at 16 time points. SAV3 was concentrated from the water by filtration, using either electronegative or electropositive membrane filters, which were subsequently rinsed with one of 4 different buffer solutions. SAV3 was detected first in tank water (7 d post-challenge, DPC), and later in cohabitant fish organ tissue samples (12 DPC). The electronegative filter (MF-Millipore™) and rinsing with NucliSENS® easyMAG® Lysis Buffer presented the best SAV3 recovery. A significant positive correlation was found between SAV3 in the tank water concentrates and the mid-kidney samples. Based on these results, detection of SAV3 in filtrated seawater is believed to have the potential to serve as an alternative method for surveillance of SAV in Atlantic salmon farms.


Asunto(s)
Infecciones por Alphavirus , Alphavirus , Enfermedades de los Peces , Salmo salar , Infecciones por Alphavirus/veterinaria , Animales , Noruega , Agua de Mar
7.
Tidsskr Nor Laegeforen ; 141(4)2021 03 09.
Artículo en Inglés, No | MEDLINE | ID: mdl-33685110

RESUMEN

BACKGROUND: Interest has been shown in the use of antibiotics during the COVID-19 pandemic. In this article we present the consumption of systemic antibiotics in Norway during the period of the pandemic. MATERIAL AND METHOD: Total sales of systemic antibiotics in defined daily doses (DDD) were retrieved from the wholesaler-based medicinal product statistics for 2019 and 2020, and sales of antibiotics for use outside of healthcare institutions were retrieved from the Norwegian prescription database. Information was retrieved on the proportion of users (prevalence), doses (measured in DDD) and prescriptions. RESULTS: Total sales of systemic antibiotics increased in March 2020, but sales to persons outside of healthcare institutions did not. Compared to previous years, both total consumption and use of antibiotics outside of institutions fell steeply in the months that followed. The reduction was greatest for antibiotics against respiratory infections and in the youngest age groups. INTERPRETATION: The significant reduction in the use of systemic antibiotics during the COVID-19 pandemic is attributed to infection control measures and reduced contact with the health service. In 2016, the Norwegian government set a goal for a 30 % reduction in antibiotic use by the end of 2020. The pandemic has contributed to the achievement of that goal.


Asunto(s)
Antibacterianos/administración & dosificación , Prescripciones de Medicamentos/estadística & datos numéricos , Pandemias , Utilización de Medicamentos , Humanos , Noruega/epidemiología
8.
Physiother Theory Pract ; 37(3): 432-446, 2021 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-33715579

RESUMEN

Enhancing and facilitating change or optimization of body awareness and movement behaviors have been sustained throughout history as central objectives in physiotherapy. Focus will be on the thoughts and practice of orthopedist Gunder Nielsen Kjølstad (1794-1860). He is, in a Norwegian context, one of the forefathers of physiotherapy. Kjølstad was unique for his time in the sense that he did not limit himself to medicine, but drew on vast array of disciplines, among them philosophy, geometry, physics, and dance. Fundamental to his treatment method was a pedagogy that rested on the active participation of the patient; an approach that stood in stark contrast to the established clinical practices. Through this approach, he developed a treatment for 'crooked backs' which constituted a historic break with the common treatment regimens of the nineteenth century.


Asunto(s)
Ortopedia/historia , Modalidades de Fisioterapia/historia , Fisioterapia/historia , Escoliosis/terapia , Historia del Siglo XVIII , Historia del Siglo XIX , Humanos , Noruega
9.
BMC Geriatr ; 21(1): 199, 2021 03 22.
Artículo en Inglés | MEDLINE | ID: mdl-33752614

RESUMEN

BACKGROUND: Older people are particularly vulnerable to severe COVID-19. Little is known about long-term consequences of COVID-19 on health-related quality of life (HR-QoL) and functional status in older people, and the impact of age in this context. We aimed to study age-related change in health-related quality of life, functional decline and mortality among older patients 6 months following hospitalisation due to COVID-19. METHODS: This was a cohort study including patients aged 60 years and older admitted to four general hospitals in South-Eastern Norway due to COVID-19, from March 1 up until July 1, 2020. Patients who were still alive were invited to attend a six-month follow-up. Change in HR-QoL and functional status compared to before the COVID-19 hospitalisation were assessed using the EuroQol 5-dimensional-5 levels questionnaire (EQ. 5D-5L). A change in visual analogue scale (VAS) score of 7 or more was considered clinically relevant. RESULTS: Out of 216 patients aged 60 years and older that were admitted to hospital due to COVID-19 during the study period, 171 were still alive 180 days after hospital admission, and 106 patients (62%) attended the six-month follow-up. Mean age was 74.3 years, 27 patients (26%) had experienced severe COVID-19. Fifty-seven participants (54%) reported a decrease in the EQ. 5D-5L VAS score after 6 months, with no significant difference between persons aged 75 years and older compared to younger. Seventy participants (66%) reported a negative change in any of the dimensions of the EQ. 5D-5L, with impaired ability to perform activities of daily life (35%), reduced mobility (33%) and having more pain or discomfort (33%) being the most commonly reported changes. Forty-six participants (43%) reported a negative change in cognitive function compared to before the COVID-19 hospitalisation. Six-month mortality was 21%, and increased with increasing age. CONCLUSIONS: More than half of the patients reported a negative change in HR-QoL 6 months following hospitalisation due to COVID-19, and one out of three experienced a persistently impaired mobility and ability to carry out activities of daily living. The results suggest awareness of long-term functional decline in older COVID-19 patients.


Asunto(s)
Calidad de Vida , Actividades Cotidianas , Anciano , Anciano de 80 o más Años , Estudios de Cohortes , Hospitalización , Humanos , Persona de Mediana Edad , Noruega/epidemiología , Encuestas y Cuestionarios
10.
Artículo en Inglés | MEDLINE | ID: mdl-33672759

RESUMEN

This population-based study assessed the prevalence and determinants of symptom-defined post-traumatic stress disorder (PTSD) in a cohort of hospitalized and non-hospitalized patients about 1.5-6 months after their COVID-19 onset. The data were acquired from two mixed postal/web surveys in June-September 2020 from patients all aged ≥18 years with a positive polymerase chain reaction for severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) until 1 June 2020, comprising both hospitalized and non-hospitalized subjects. The catchment areas of the two included hospitals covers about 17% of the population of Norway. In total, 211 hospitalized and 938 non-hospitalized subjects received invitation. The prevalence of symptom-defined PTSD was assessed using the PTSD checklist for DSM-5 (PCL-5). Determinants of symptom-defined PTSD and PTSD symptoms were analyzed using multivariable logistic and linear regression analysis. In total, 583 (51%) subjects responded at median 116 (range 41-200) days after COVID-19 onset. The prevalence of symptom-defined PTSD was 9.5% in hospitalized and 7.0% in non-hospitalized subjects (p = 0.80). Female sex, born outside of Norway, and dyspnea during COVID-19 were risk factors for persistent PTSD symptoms. In non-hospitalized subjects, previous depression and COVID-19 symptom load were also associated with persistent PTSD symptoms. In conclusion, COVID-19 symptom load, but not hospitalization, was associated with symptom-defined PTSD and PTSD symptom severity.


Asunto(s)
/psicología , Trastornos por Estrés Postraumático , Adulto , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Noruega/epidemiología , Prevalencia , Factores de Riesgo , Trastornos por Estrés Postraumático/epidemiología
11.
BMC Infect Dis ; 21(1): 137, 2021 Feb 01.
Artículo en Inglés | MEDLINE | ID: mdl-33526010

RESUMEN

BACKGROUND: The use of complement inhibition is well established for complement mediated thrombotic microangiopathy, but its role in secondary forms of thrombotic microangiopathy is debated. We here present a case of thrombotic microangiopathy triggered by Capnocytophaga canimorsus, illustrating the diagnostic difficulties in discriminating between different thrombotic microangiopathies, and the dilemmas regarding how to treat this disease entity. CASE PRESENTATION: A previously healthy 56-year-old woman presented with fever and confusion. She was diagnosed with sepsis from Capnocytophaga canimorsus and thrombotic microangiopathy. Marked activation of both T-cells, endothelium and complement were documented. She was successfully treated with antimicrobial therapy, the complement inhibitor eculizumab and splenectomy. After several weeks, a heterozygote variant in complement factor B was localized, potentially implying the diagnosis of a complement mediated TMA over an isolated infection related TMA. CONCLUSIONS: We discuss the possible interactions between complement activation and other findings in severe infection and argue that complement inhibition proved beneficial to this patient's rapid recovery.


Asunto(s)
Anticuerpos Monoclonales Humanizados/uso terapéutico , Capnocytophaga/patogenicidad , Activación de Complemento , Inactivadores del Complemento/uso terapéutico , Microangiopatías Trombóticas/diagnóstico , Microangiopatías Trombóticas/tratamiento farmacológico , Femenino , Infecciones por Bacterias Gramnegativas , Humanos , Persona de Mediana Edad , Noruega/epidemiología , Sepsis/etiología
13.
Scand J Prim Health Care ; 39(1): 31-34, 2021 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-33544016

RESUMEN

Objective: We aim to discuss whether preventive quarantine can mitigate the spread of Covid-19 during the pandemic. Design: We did a cross-sectional, observational study design in a mass-screening program in the enrolment to the Norwegian military during April 19-28th 2020 (COVID-NOR-MIL). Subjects: 1170 presumptively healthy young Norwegian conscripts. Setting: A structured interview encouraged the coming conscripts to a self-imposed preventive quarantine the last two weeks before enrolment. Main outcome measures: All conscripts underwent a PCR-based test with nasopharyngeal swabs at the day of enrolment. Results: Only two tested positive. The study discusses the predictive value of the RT-PCR test and the risk of false positive and false negative results, particularly when using the test in a low-prevalent cohort, even if the test properties of sensitivity and specificity is almost 100%. Further, the study discusses the challenge of whether a positive SARS-CoV-2 PCR-test represent viable and contagious virus or only viral remnants. Conclusion: The adherence to self-imposed preventive quarantine is a challenge and is a subject to further research. Implications: We want to draw the attention to the potential value of a thorough pre-screening processes and self-imposed preventive quarantine to minimize the potential spread of SARS-Cov-2.


Asunto(s)
/prevención & control , Tamizaje Masivo , Personal Militar , Pandemias/prevención & control , Cuarentena , /diagnóstico , Estudios de Cohortes , Estudios Transversales , Humanos , Noruega/epidemiología , Prevalencia , Evaluación de Programas y Proyectos de Salud , Sensibilidad y Especificidad
14.
Nutr Metab Cardiovasc Dis ; 31(4): 1299-1307, 2021 04 09.
Artículo en Inglés | MEDLINE | ID: mdl-33549456

RESUMEN

BACKGROUND AND AIMS: Both the Nordic and Mediterranean diets claim to have a beneficial effect on lipid metabolism and cardiovascular prevention. The objective of this study was to compare diets consumed by children with FH at the time of diagnosis in Norway and Spain and to study their relationship with the lipid profile. METHODS AND RESULTS: In this cross-sectional study, we appraised the dietary intake in children (4-18 years old) with (n = 114) and without FH (n = 145) from Norway and Spain. We compared Nordic and Mediterranean diet composition differences and determined the association between food groups and lipid profiles. RESULTS: The Spanish FH group had a higher intake of total fats (mainly monounsaturated fatty acids (MUFAs)), cholesterol and fibre, but a lower intake of polyunsaturated fatty acids (PUFAs) compared to the Norwegian FH group. The Norwegian children consumed more rapeseed oil, low-fat margarine and whole grains and less olive oil, eggs, fatty fish, meat, legumes and nuts. In the Norwegian FH group, fat and MUFAs were directly correlated with total cholesterol, low-density lipoprotein cholesterol and apolipoprotein B and inversely correlated with high-density lipoprotein (HDL-C). In Spanish children with FH, the intake of fats (mainly MUFAs) was directly associated with HDL-C and apolipoprotein A1. CONCLUSIONS: Despite a similar lipid phenotype, diets consumed by children with FH in Norway and Spain have significant differences at time of diagnosis. Nutrition advice should be more adapted to local intake patterns than on specific nutrient composition.


Asunto(s)
Enfermedades Cardiovasculares/prevención & control , Dieta Saludable , Dieta Mediterránea , Grasas de la Dieta/administración & dosificación , Grasas de la Dieta/sangre , Hiperlipoproteinemia Tipo II/dietoterapia , Adolescente , Biomarcadores/sangre , Enfermedades Cardiovasculares/sangre , Enfermedades Cardiovasculares/diagnóstico , Enfermedades Cardiovasculares/etnología , Niño , Preescolar , Estudios Transversales , Características Culturales , Dieta Saludable/etnología , Dieta Mediterránea/etnología , Conducta Alimentaria/etnología , Femenino , Humanos , Hiperlipoproteinemia Tipo II/sangre , Hiperlipoproteinemia Tipo II/diagnóstico , Hiperlipoproteinemia Tipo II/etnología , Masculino , Noruega , Valor Nutritivo , España
15.
Psychiatry Res ; 298: 113779, 2021 04.
Artículo en Inglés | MEDLINE | ID: mdl-33561619

RESUMEN

This current cross sectional survey was carried out amongst patients and staff in an acute psychiatric inpatient unit in the very first weeks of the ongoing pandemic outbreak of COVID-19 in Norway. Most patients found the visiting restrictions difficult, many reported that the pandemic made them feel unsafe, affected their sleep and that they feared transmission from other patients. Among staff, almost half were afraid that they would contract the virus, a majority feared they would bring the virus home and infect their family and one third were concerned that the pandemic compromised the treatment provided for the patients.


Asunto(s)
Actitud del Personal de Salud , Conocimientos, Actitudes y Práctica en Salud , Pacientes Internos/psicología , Trastornos Mentales/psicología , Trastornos Mentales/terapia , Personal de Hospital/psicología , Servicio de Psiquiatría en Hospital , Enfermedad Aguda , Adulto , Estudios Transversales , Femenino , Humanos , Masculino , Persona de Mediana Edad , Noruega
16.
Physiother Theory Pract ; 37(3): 420-431, 2021 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-33586609

RESUMEN

The history of physiotherapy can be seen as a history of boundary conflict, as the profession sought to first establish, then maintain, its distinctive professional identity. Traditional approaches to the sociology of the professions support this, seeing professionalization as an ongoing process of enclosure, encroachment, and conflict. Recent work, however, has emphasized the fluidity and collaborative nature of professionalization projects, and placed more emphasis on inter-professional negotiations and disciplinary coexistence. In this paper, we draw on this work to analyze the harmonization of the independent Mensendieck System of medical gymnastics in Norway, and the emerging state-sponsored physiotherapy system. Our contention is that over the course of the middle decades of the 20th century, advocates of the Mensendieck System and providers of orthodox, biomedically informed physiotherapy, came together and found a way to work collaboratively in a shared space without compromising their distinctive professional identities. We argue that this approach both points to ways we might revisit traditional conflict-based analyses of the history of physiotherapy, while also suggesting new ways of imagining how the profession might change in the years to come.


Asunto(s)
Fisioterapia/educación , Fisioterapia/historia , Autonomía Profesional , Especialización/historia , Historia del Siglo XX , Humanos , Modelos Teóricos , Noruega
17.
Tidsskr Nor Laegeforen ; 140(2)2021 02 02.
Artículo en Inglés, No | MEDLINE | ID: mdl-33528146

RESUMEN

BACKGROUND: Cardiovascular disease and cancer have been described as possible risk factors for COVID-19 mortality. The purpose of this study was to investigate whether a history of cardiovascular disease or cancer affects the risk of dying after a COVID-19 diagnosis in Norway. MATERIAL AND METHOD: Data were compiled from the Norwegian Surveillance System for Communicable Diseases, the Norwegian Cardiovascular Disease Registry and the Cancer Registry of Norway. Univariable and multivariable regression models were used to calculate both relative and absolute risk. RESULTS: In the first half of 2020, 8 809 people tested positive for SARS-CoV-2 and 260 COVID-19-associated deaths were registered. Increasing age, male sex (relative risk (RR): 1.5; confidence interval (CI): 1.2-2.0), prior stroke (RR: 1.5; CI: 1.0-2.1) and cancer with distant metastasis at the time of diagnosis (RR: 3.0; CI: 1.1-8.2) were independent risk factors for death after a diagnosis of COVID-19. After adjusting for age and sex, myocardial infarction, atrial fibrillation, heart failure, hypertension, and non-metastatic cancer were no longer statistically significant risk factors for death. INTERPRETATION: The leading risk factor for death among individuals who tested positive for SARS-CoV-2 was age. Male sex, and a previous diagnosis of stroke or cancer with distant metastasis were also associated with an increased risk of death after a COVID-19 diagnosis.


Asunto(s)
/mortalidad , Enfermedades Cardiovasculares/complicaciones , Neoplasias/complicaciones , Femenino , Humanos , Masculino , Noruega/epidemiología , Factores de Riesgo
18.
Artículo en Inglés | MEDLINE | ID: mdl-33572994

RESUMEN

Whether lockdown related to the COVID-19 pandemic influences alcohol consumption is not well known. This study assesses alcohol consumption and hazardous drinking behavior during the initial phase of pandemic measures in Norway and identifies potential risk factors. A cross-sectional study (N = 25,708) was conducted in Bergen, Norway, following the first six weeks of strict infection control measures. In a model of self-assessed increased alcohol consumption, logistic regression analysis was conducted with independent variables for COVID-19-related worries, joblessness, quarantine, self-reported drinking behavior, age, gender, and occupational situation. These are reported with odds ratios (ORs) with 95% confidence intervals. Fifty-one percent of respondents reported economic or health-related worries due to COVID-19, 16% had been in quarantine, 49% worked/studied from home, 54% reported hazardous drinking behavior, and 13% reported increased alcohol consumption. People aged 30-39 years had elevated odds of increased alcohol consumption during lockdown (OR 3.1, 2.4-3.8) compared to the oldest adults. Increased drinking was more frequent among people reporting economic worries (OR 1.6, 1.4-1.8), those quarantined (OR 1.2, 1.1-1.4), and those studying or working at home (OR 1.4, 1.3-1.6). More than half of respondents reported hazardous drinking behavior. Increased alcohol consumption during lockdown was common among people with economic worries, people in quarantine, and people studying or working at home. These data could be important when adjusting pandemic measures.


Asunto(s)
Consumo de Bebidas Alcohólicas/tendencias , Control de Enfermedades Transmisibles , Pandemias , Adolescente , Adulto , Anciano , Consumo de Bebidas Alcohólicas/epidemiología , Estudios Transversales , Femenino , Humanos , Masculino , Persona de Mediana Edad , Noruega/epidemiología , Cuarentena , Adulto Joven
19.
Transfus Apher Sci ; 60(2): 103092, 2021 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-33612447

RESUMEN

Little more than a year after the first reports of a new coronavirus in Wuhan, China, the world is in the middle of a pandemic that has brought dramatic changes in societies all over the world. This is our story, as seen from the Department of Immunology and Transfusion at Oslo University Hospital (OUH).


Asunto(s)
Hospitales Universitarios , Pandemias , /epidemiología , China/epidemiología , Humanos , Noruega/epidemiología
20.
J Environ Manage ; 284: 111997, 2021 Apr 15.
Artículo en Inglés | MEDLINE | ID: mdl-33524868

RESUMEN

In this study, a framework for integrating weather variables and seasons into the modelling and prediction of the microbial quality in drinking water distribution networks is presented. Statistical analysis and Bayesian network (BN) modelling were used to evaluate relationships among water quality parameters in distribution pipes and their dependencies on weather parameters. Two robust predictive models for Total Bacteria in the network were built based on a deep learning approach (Long Short-Term Memory (LSTM)). The first model included water quality parameters alone as inputs while the second model included weather parameters. The seven-year dataset used in this study constituted water quality parameters measured at seven location in the water distribution network for the city of Ålesund in Norway, and weather data for the same period. Results of the initial statistical analysis and the BN models showed that, air temperature, the summer season, precipitation, as well as water quality parameters namely, residual chlorine, water temperature, alkalinity and electrical conductivity have strong relations with the counts of Total Bacteria in the distribution networks studied. It was found that the integration of the weather parameters in the Total Bacteria prediction models significantly improved the quality of the predictions. Compared to the LSTM 1, LSTM 2 achieved MAE and MSE values as high as to 6.8 and 4.9 times respectively when the model was tested on the seven locations. In addition, the R2 values were marginally higher in LSTM 2 (0.92-0.95) than in LSTM (0.81-0.86). The prediction results demonstrate the relevance of integrating weather parameters such as air temperature seasons in predicting bacteria levels in water distribution systems. This suggests that changes in the microbial quality of water in distribution systems and potentially drinking water sources could be reliably assessed by integrating online sensors of water quality and weather parameters with efficient models such as the LSTM. Applying this efficient modelling approach in the management of water supply systems could offer immense support in addressing current challenges in assessing the microbial quality of water and minimizing associated health risks.


Asunto(s)
Agua , Tiempo (Meteorología) , Teorema de Bayes , Noruega , Calidad del Agua
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