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1.
J Oral Sci ; 63(2): 191-194, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33790090

RESUMEN

PURPOSE: To investigate the effect of slurry abrasive levels and acidic challenges on the development of non-carious cervical lesions. METHODS: Ninety-six extracted upper premolars were affixed in pairs to acrylic blocks and had their root surfaces covered by acrylic resin except for 2 mm from the cemento-enamel junction. The specimens were distributed into six groups (n = 8 pairs) based on two experimental factors: (1) slurry abrasivity level [low/medium/high] and (2) citric acid challenge [yes/no]. Specimens were brushed for 5,000, 15,000, 35,000, and 65,000 strokes. Volume loss (VL) was determined based on optical profilometry scans of specimens impressions at the baseline and at subsequent brushing levels. Data were analyzed using repeated measures analysis of variance and Bonferroni pairwise comparison (α = 0.05). RESULTS: Higher VL values were associated with high-abrasivity slurries relative to low- and medium-abrasivity slurries (P < 0.001). Increasing the slurry abrasivity level increased the VL regardless of the acidic challenge, which did not have a significant effect (P = 0.184). After 65,000 strokes, significant VL was recorded in all groups relative to preceding brushing levels (P < 0.001). CONCLUSION: Higher values of time-dependent surface loss were associated with increased dentifrice slurry abrasivity, regardless of the citric acid challenge.


Asunto(s)
Dentífricos , Abrasión de los Dientes , Erosión de los Dientes , Humanos , Abrasión de los Dientes/etiología , Cuello del Diente , Erosión de los Dientes/etiología , Cepillado Dental , Pastas de Dientes
2.
Oral Health Prev Dent ; 19(1): 195-202, 2021 Jan 07.
Artículo en Inglés | MEDLINE | ID: mdl-33723979

RESUMEN

PURPOSE: A novel anhydrous toothpaste formulation has been developed containing the anti-dentinal hypersensitivity (DH) ingredient stannous fluoride (SnF2). MATERIALS AND METHODS: This randomised, controlled, examiner-blind, parallel-group, stratified (by baseline Schiff sensitivity score) study compared efficacy of an experimental 'Test' toothpaste (n = 67) containing 0.454% SnF2, 0.072% sodium fluoride and 5% sodium tripolyphosphate (all percentages w/w) with a negative 'Control' 0.76% sodium monofluorophosphate toothpaste (n = 68) in relieving DH in healthy Chinese adults. After 4-6 weeks acclimatisation, DH was assessed at baseline and following 4 and 8 weeks' twice-daily brushing by response to evaporative (air) (Schiff sensitivity score) and tactile (Yeaple probe) stimuli. An analysis of covariance model was used (factor: treatment group; covariate: baseline Schiff sensitivity score). RESULTS: Both Test and Control toothpastes statistically significantly reduced Schiff sensitivity score from baseline after 8 weeks' use; the Test toothpaste also statistically significantly reduced the score after 4 weeks' use (all p < 0.001). The Test toothpaste reduction was statistically significantly superior to the Control toothpaste reduction at both timepoints (p < 0.001). Percentage differences in treatment effects between Test and Control groups were 24.1% at 4 weeks and 31.7% at 8 weeks. Tactile threshold scores for both treatments statistically significantly increased from baseline at both timepoints (all p < 0.001); however, there were no statistically significant differences between Test and Control groups. Both toothpastes were well-tolerated with no adverse events reported. CONCLUSION: The Test toothpaste containing 0.454% SnF2 reduced DH statistically significantly more than the Control as evaluated by the Schiff sensitivity score, but not by tactile threshold.


Asunto(s)
Desensibilizantes Dentinarios , Sensibilidad de la Dentina , Adulto , Desensibilizantes Dentinarios/uso terapéutico , Sensibilidad de la Dentina/tratamiento farmacológico , Método Doble Ciego , Fluoruros/uso terapéutico , Humanos , Fluoruro de Sodio/uso terapéutico , Tecnología , Pastas de Dientes/uso terapéutico , Resultado del Tratamiento
3.
Artículo en Inglés | MEDLINE | ID: mdl-33652982

RESUMEN

The COVID-19 pandemic has drawn attention to microbial transmission risk via aerosols in dental practice. Demonstration electric toothbrushes are used intra-orally for education. The aim of this investigation was to measure the size of droplets emitted by the brush head of two demonstration oscillating-rotating electric toothbrushes. Measurement of droplet production and size was recorded in vitro using three methods: (1) Malvern Spraytec (LASER particle size measurement device with detectable particle size of 0.1-2500 µm) and brushes mounted on a 3D-printed, two-shell form-fit fixture with a supply of tap water; (2) a DustTrak aerosol measurement device and toothpaste slurry, with brushing simulated in the oral cavity of a phantom head; (3) high-speed visualization in a simulated-use situation in the oral cavity of a phantom head, with individual evaluation of tap water, water with detergent, 70% ethanol, glycerin and toothpaste slurry. Both brushes showed the size of emitted droplets was consistently between 200 and 1200 µm, categorized as splatter (dental aerosols are <50 µm diameter). No significant incremental aerosol-sized matter was detected during toothbrush operation. The high-speed video visualization confirmed only splatter-sized droplets during operation. These findings indicate that oscillating-rotating toothbrushes do not produce aerosol-sized particles during simulated use.


Asunto(s)
Aerosoles/análisis , Equipo Dental , Cepillado Dental/instrumentación , Diseño de Equipo , Pastas de Dientes
4.
Braz Oral Res ; 35: e025, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33605355

RESUMEN

This in vitro study evaluated the biocompatibility and abrasivity of whitening and conventional toothpastes. Samples of conventional (non-whitening) - Edel White Infant (EWI) - and whitening toothpastes - Edel White Whitening (EWW), Edel White CAREFORTE (EWC), Colgate Total 12 Ò Professional (C), and Oral-B Whitening (OB) - were dissolved in culture medium (0.2 g sample weight per mL). Human gingival fibroblasts (hGF) were placed in contact with different dilutions of culture media that had been previously exposed to these toothpastes. Cytotoxicity was then assessed using the methyl tetrazolium test (MTT) and the cell survival rate was determined. Genotoxicity was assessed by the micronucleus test (MNT) and the number of micronuclei was determined before and after exposure to the toothpaste solutions. The enamel surface roughness was evaluated in specimens of bovine teeth (n = 10 per group) before and after 10,000 brushing cycles, using the investigated toothpastes. The results were statistically analyzed using the Mann-Whitney U test and two-way ANOVA (p < 0.05). According to the MTT assay, EWW and OB presented significant cytotoxicity (p < 0.01), but no genotoxic (MNT) effects (p > 0.05). C toothpaste was statistically significantly abrasive to the enamel surface (p < 0.01). The findings of this study may be helpful for individualized selection of commercial toothpastes, as some whitening toothpastes present significant cytotoxicity and conventional toothpaste cause significant surface changes.


Asunto(s)
Esmalte Dental , Pastas de Dientes , Animales , Bovinos , Humanos , Fluoruro de Sodio , Cepillado Dental , Pastas de Dientes/toxicidad
5.
In Vitro Cell Dev Biol Anim ; 57(2): 148-159, 2021 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-33447968

RESUMEN

Three-dimensional, organotypic models of the oral mucosa have been developed to study a wide variety of phenomena occurring in the oral cavity. Although a number of models have been developed in academic research labs, only a few models have been commercialized. Models from academic groups offer a broader range of phenotypes while the commercial models are more focused on the oral and gingival mucosa. The commercialized models are manufactured under highly controlled conditions and meet the requirements of quality standards, which leads to high levels of reproducibility. These in vitro models have been used to evaluate the irritancy of oral care products such as toothpastes, mouthwashes, and mucoadhesives. The effects of cigarette smoke on oral cavity tissues have been studied and compared to those of e-cigarettes. Oral tissue models have facilitated investigation of the mechanisms of oral mucositis and oral candidiasis and have been used to examine transbuccal drug delivery rates and the absorption of nanoparticles. Infection studies have investigated the effects of HIV-1 along with the effects of commensal and pathogenic bacteria. More recently, a differentiated oral tissue model has been shown to express the ACE2 receptor, which is known to be important for the receptor-mediated entry of the SARS-CoV-2 coronavirus into human cells and tissues. Hence, oral mucosal models may find application in determining whether viral infection of the oral mucosa is possible and whether such infection has implications vis-a-vis the current COVID-19 pandemic. As is apparent, these models are used in a broad variety of applications and often offer advantages versus animal models in terms of reproducibility, avoiding species extrapolation, and the ethical concerns related to human and animal experimentation. The goals of this paper are to review commercially available models of the human buccal and gingival mucosa and highlight their use to gain a better understanding of a broad range of phenomena affecting tissues in the oral cavity.


Asunto(s)
Materiales Dentales/efectos adversos , Infecciones , Mucosa Bucal/citología , Mucosa Bucal/virología , Técnicas de Cultivo de Tejidos/métodos , /transmisión , Sistemas de Liberación de Medicamentos/efectos adversos , Sistemas de Liberación de Medicamentos/métodos , Humanos , Infecciones/microbiología , Infecciones/virología , Boca , Mucosa Bucal/microbiología , Mucosa Bucal/patología , Control de Calidad , Técnicas de Cultivo de Tejidos/instrumentación , Ingeniería de Tejidos , Tabaco , Pastas de Dientes/efectos adversos , Rayos Ultravioleta/efectos adversos
6.
Artículo en Inglés | MEDLINE | ID: mdl-33478112

RESUMEN

Enzymes in toothpastes can support host immune responses, and thus maintain oral health. This study aimed to investigate gingival health and the plaque-reducing effects of enzyme-containing toothpastes. A laboratory study tested the antimicrobial potential of different enzyme-containing toothpaste formulations. Two promising formulations (enzyme-containing toothpastes with glucose oxidase and D-glucose with (C+) and without Citrox (C-) Citrox) were investigated in a clinical crossover trial (two slurries: sodium lauryl sulfate-containing (SLS), a toothpaste without SLS (reference), and water). Subjects (n = 20) abstained from toothbrushing for four days and rinsed with a toothpaste slurry. Bleeding on probing (BOP) and plaque indices (PI) were measured. A mixed linear model was used to statistically compare the slurries with respect to BOP and PI change. The in vitro bacterial growth-inhibiting evaluation showed the best results for SLS, followed by C+ and C-. The change in BOP and PI exhibited statistically significant differences to water rinsing (BOP; PI changes in % points (difference of the baseline and post-rinse values: water = 8.8%; 90.0%; C+ = -1.4%; 80.4%; SLS = 1.5%; 72.1%; reference = 0.8%; 77.5%; C- = -1.8%; 75.1%). All slurries exhibited anti-gingivitis and anti-plaque effects, resulting in a prophylactic benefit for limited-access regions during brushing.


Asunto(s)
Gingivitis , Pastas de Dientes , Método Doble Ciego , Encía , Humanos , Dodecil Sulfato de Sodio , Cepillado Dental
7.
Monogr Oral Sci ; 29: 65-73, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33427212

RESUMEN

The formation of a physiological biofilm cannot be avoided under normal circumstances. However, the consequences of a supragingivally located biofilm, such as caries, gingivitis and, as a further effect, periodontitis, are relatively easy to avoid. The simplest and most common method used worldwide for the elimination of biofilm is periodic mechanical removal using a toothbrush or similar tools, such as chewing sticks or woods. This method was already used in ancient Egypt, and is still being used today, albeit advanced and improved with the help of toothpastes. Here we give a summary of the most common toothbrushes, highlighting their advantages and disadvantages. Furthermore, we provide an overview of the most common toothpastes, their ingredients, and functions. In addition, the ingredients will be critically evaluated and recommendations given for the use or non-use of certain ingredients for different target groups, such as children, healthy adults, or patients with special needs.


Asunto(s)
Placa Dental , Gingivitis , Adulto , Biopelículas , Niño , Humanos , Cepillado Dental , Pastas de Dientes
8.
Quintessence Int ; 0(0): 318-326, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33491385

RESUMEN

Objective: This study aimed to examine and compare the anti-caries effects of slightly acidic 1% NaF-HF gel when applied once or twice (7-day or 6-month interval) to mandibular first molars in 6- to 7-year-old children. Method and materials: This was a 1-year, multi-arm, placebo-controlled, double-blind, parallel-group randomized trial. In total, 1,077 schoolchildren from eight primary schools were allocated to one of the four study groups (group 1, single application; group 2, two applications with a 7-day interval; group 3, two applications with a 6-month interval; group 4, placebo control). The occlusal surfaces of permanent mandibular first molars were examined by three calibrated examiners who were blind to the group allocation at baseline and the end of the study. Caries reduction and prevented fraction was assessed. Results: A total of 986 children completed the study. There was a statistically significant difference in the mean D1MFT increment across the groups (P < .001). The mean D1MFT increment was 0.37 in group 1 (single application), 0.18 in group 2 (two applications with a 7-day interval), 0.21 in group 3 (two applications with a 6-month interval), and 0.56 in the control group. The mean D2MFT increments (0.22 in group 1, 0.06 in group 2, 0.18 in group 3, and 0.50 in the control group) also showed a statistically significant difference across the groups (P < .001). Conclusion: Subacidic 1% NaF-HF gel exerts a high preventive effect on caries (more than 40%) when applied twice at a 7-day interval in 6- to 7-year-old schoolchildren who do not use fluoride toothpaste in areas where drinking water is not fluoridated.


Asunto(s)
Cariostáticos , Caries Dental , Niño , Caries Dental/prevención & control , Método Doble Ciego , Humanos , Diente Molar , Pastas de Dientes
9.
Arch Oral Biol ; 122: 105001, 2021 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-33316658

RESUMEN

OBJECTIVE: To evaluate the effects of combination of treatments with fluoridated toothpastes supplemented with sodium trimetaphosphate (TMP) and casein phosphopeptide-amorphous calcium phosphate (MI Paste Plus®), on the remineralization of dental enamel. DESIGN: Enamel blocks with artificial caries were randomly allocated into six groups (n = 12), according to the toothpastes: 1) without F-TMP-MI Paste Plus® (Placebo); 2) 1100 ppm F (1100 F), 3) MI Paste Plus®, 4) 1100 F + MI Paste Plus® (1100 F-MI Paste Plus®), 5) 1100 F + 3% TMP (1100 F-TMP) and 6) 1100 F-TMP + MI Paste Plus® (1100 F-TMP-MI Paste Plus®). Blocks were treated 2×/day with slurries of toothpastes (1 min). Furthermore, groups 4 and 6 received the application of MI Paste Plus® for 3 min. After pH cycling, the percentage of surface hardness recovery (%SHR); integrated loss of subsurface hardness (ΔKHN); profile analysis and lesion depth subsurface through polarized light microscopy (PLM), confocal laser scanning microscopy (LSCM), scanning electron microscopy (SEM), fluoride (F), calcium (Ca), phosphorus (P) concentrations in the enamel were determined. The data were analyzed by ANOVA (1-criterion) and Student-Newman-Keuls test (p < 0.001). RESULTS: 1100 F-TMP-MI Paste Plus® group showed the best results of %SHR, ΔKHN and PLM (p < 0.001). F concentration was similar between the 1100 F, 1100 F-MI Paste Plus®, and 1100 F-TMP-MI Paste Plus® groups (p > 0.001). 1100 F-TMP-MI Paste Plus® group showed the highest concentration of Ca and P in the enamel (p < 0.001). CONCLUSION: The association of 1100 F-TMP and MI Paste Plus® led to a significant increase in the remineralization of initial carious lesions.


Asunto(s)
Fosfatos de Calcio/farmacología , Cariostáticos/farmacología , Esmalte Dental/efectos de los fármacos , Fluoruros/farmacología , Polifosfatos/farmacología , Remineralización Dental , Caseínas/farmacología , Caries Dental/tratamiento farmacológico , Humanos , Técnicas In Vitro , Fosfopéptidos/farmacología , Distribución Aleatoria , Pastas de Dientes/farmacología
11.
12.
Medicine (Baltimore) ; 99(45): e23092, 2020 Nov 06.
Artículo en Inglés | MEDLINE | ID: mdl-33157981

RESUMEN

BACKGROUND: Dental biofilm accumulation and poor personal oral hygiene are known major risk factors for gingivitis and halitosis. However, it is not clear how studies compare the effectiveness of hygiene regimens, associated with outcomes centered on patients. METHODS: A randomized, blind, controlled clinical trial involving 58 participants aged from 12 to 17 years, who search the Department of Pediatric Dentistry of Universidade Metropolitana de Santos, will be conducted. Immediately, the volunteers will be inserted into Group 1 (commercially available hygiene regimen) or Group 2 (tooth brushing alone). In Group 1, participants will receive Colgate Total 12 toothpastes, Plax mouthwashes and Colgate Ultrasoft toothbrushes, while Group 2 will use Colgate Cavity Protection toothpastes and Colgate Ultrasoft toothbrushes. The interventions will be conducted in the periods of 1, 3, and 6 months after the baseline, when the evaluations will also be performed. Biofilm and halitosis indexes will be evaluated. Data regarding discomfort, satisfaction and the socioeconomic/individual characteristics will also be computed. DISCUSSION: Although toothbrushing has shown positive effects in decreasing biofilm and in gingival health, there is no comparison in the literature of different brushing regimens with halitosis measurement in adolescents. In addition, the effectiveness of these protocols would be confirmed from the acceptability of the volunteers.


Asunto(s)
Placa Dental/terapia , Dentífricos/uso terapéutico , Gingivitis/terapia , Halitosis/terapia , Ensayos Clínicos Controlados Aleatorios como Asunto/métodos , Cepillado Dental , Pastas de Dientes/uso terapéutico , Adolescente , Niño , Humanos , Ácido Silícico/uso terapéutico , Método Simple Ciego , Resultado del Tratamiento
13.
J Clin Pediatr Dent ; 44(5): 332-341, 2020 Sep 01.
Artículo en Inglés | MEDLINE | ID: mdl-33181840

RESUMEN

OBJECTIVE(S): To: 1) examine the fluoride concentrations in commercial child formula dentifrices (CFD)s; and 2) investigate the effect of arginine incorporation in CFDs on fluoride bioavailability. STUDY DESIGN: Five commercial CFDs were examined for fluoride concentrations. Total, total soluble, and insoluble fluorides in CFDs were determined by the modified Taves acid-diffusion method (TAD). Ionic F and MFP were estimated by modified direct method with standard addition technique. L-arginine (L-Arg)/L-arginine monohydrochloride (L-Arg.HCl) were incorporated at 2% w/w in the commercial CFDs. The pH of the toothpaste slurries, buffer capacity of the added Arg, potentially available fluorides (PAF) and 1-min PAF by TAD were determined. RESULTS: The CFDs had 4 to 32% of insoluble fluorides. Addition of L-Arg/L-Arg.HCl significantly improved the fluoride bioavailability in CFDs (p<0.05). Incorporation of L-Arg significantly increased the pH of toothpaste slurries (p<0.05); while L-Arg.HCl decreased the pH. Principal component analysis showed that L-Arg.HCl decreased the pH of toothpaste slurries due to the presence of Cl in the form of HCl; whereas the inherent elements/molecules (Na/P/Pi/F) remain distinct with unidentified influence on the variables. CONCLUSION(S): The CFDs containing NaF only have higher concentrations of bioavailable fluoride. Incorporating arginine (L-arginine or L-arginine monohydrochloride) at 2% w/w improves fluoride bioavailability of the child formula dentifrices.


Asunto(s)
Dentífricos , Fluoruros , Arginina , Disponibilidad Biológica , Cariostáticos , Niño , Humanos , Fosfatos , Fluoruro de Sodio , Pastas de Dientes
14.
J Clin Pediatr Dent ; 44(5): 296-301, 2020 Sep 01.
Artículo en Inglés | MEDLINE | ID: mdl-33181843

RESUMEN

OBJECTIVE: Whitening toothpastes are widely used. Hence, it is important to understand their effect on the surface properties of restorative materials. To evaluate the effect of three over-the-counter whitening toothpastes and toothbrushing simulation on microhardness of three restorative materials. STUDY DESIGN: Forty cylindrical (10×2mm) specimens were prepared from each restorative material and randomly assigned into four groups/10 each according to the whitening toothpastes used and distilled water (control). All specimens were measured for microhardness (Baseline-T1). The specimens were brushed with a soft brush using an in vitro tooth-brushing simulator with the assigned whitening toothpaste using the same setting for brushing cycles/load for all groups. Specimens were then measured for microhardness (T2) similar to baseline. RESULTS: The highest (mean±SD) microhardness after application of the whitening toothpastes and brushing was recorded for Intense White and Filtek Z250 XT (127.6±1.8), followed by Optic White and Fuji ll LC (73.9±0.9) and Optic White and Photac Fill (72.7±1.3). There was statistically significant difference for microhardness between pre- and post-application of the whitening toothpastes and brushing for all tested restorative materials (P=0.0001). The microhardness of Filtek Z250XT with 3D White post-application of the whitening toothpastes and brushing was lowest compared to other toothpastes and control (P=0.0001). CONCLUSION: Microhardness increased after application of the whitening toothpastes and toothbrushing simulation for all combination of tested restorative materials and whitening toothpastes. The microhardness of FIiltek Z250XT with 3D White post-application of the whitening toothpastes and brushing was lowest compared to other toothpastes and control.


Asunto(s)
Cepillado Dental , Pastas de Dientes , Estética Dental , Humanos , Propiedades de Superficie
15.
Stomatologiia (Mosk) ; 99(5): 19-24, 2020.
Artículo en Ruso | MEDLINE | ID: mdl-33034172

RESUMEN

THE AIM OF THE STUDY: Was to evaluate the abrasive effect of toothpaste with detonation nanodiamonds synthesis of various concentrations on the enamel of human teeth. MATERIALS AND METHODS: The analysis of micrographs obtained by scanning electron microscopy showed a different abrasive and polishing effect of nanodiamonds in all the observed anatomical zones on the vestibular surface of the enamel of human teeth. RESULTS: No negative effect of the paste containing nanodiamonds on the enamel of human teeth was noted. At all concentrations of pastes containing nanodiamonds, on the vestibular surface of the enamel of the studied teeth, depot areas of densely attached particles of nanodiamonds were formed, a tendency was observed towards the formation of depots. The enamel of human teeth was mostly influenced by the concentration of nanodiamonds (2%, 2.5%). On the surface of the enamel were formed not only a depot of single nanodiamonds, but also accumulations were noted, merging into a layer in the form of a protective film. CONCLUSION: The study showed that toothpastes with nanoalases can reduce the enamel porosity, form a protective film on its surface, and thereby increase its microhardness and increase caries resistance.


Asunto(s)
Nanodiamantes , Diente , Esmalte Dental , Humanos , Microscopía Electrónica de Rastreo , Pastas de Dientes
16.
J Contemp Dent Pract ; 21(6): 609-614, 2020 Jun 01.
Artículo en Inglés | MEDLINE | ID: mdl-33025927

RESUMEN

AIM: This clinical study aimed to evaluate the efficacy of a toothpaste containing a proprietary REFIX technology (Regenerador + Sensitive DentalClean, Rabbit Corp) against dentin hypersensitivity. MATERIALS AND METHODS: Fifty-three volunteers who fulfilled the inclusion criteria and signed the consent form were included. They were examined for dentin hypersensitivity. The participants received a 1-second blast of air, and the tooth sensitivity, from 0 to 10, was immediately evaluated using a visual analog scale (VAS). Then, the participants brushed their teeth with the multifunctional toothpaste, and dentin hypersensitivity was tested a second time using the same scale. The participants continued to use the toothpaste three times a day for 1 week, after which dentin hypersensitivity was recorded for the third time. Data were statistically analyzed using analysis of variance (ANOVA) and Tukey's test (α = 0.05). RESULTS: The mean patient age was 40 years, and 70% of the 53 subjects were female. There was a significant reduction in dentin hypersensitivity immediately after using the toothpaste and after 1 week. The baseline mean patient-reported pain score was severe (6.5 ± 2.4). Immediately after the first use of the toothpaste, the mean reported pain significantly decreased to mild pain (2.5 ± 2.5) (p < 0.05). After 1 week of consistent use of the toothpaste, the pain score reduced significantly (0.7 ± 1.2) (p < 0.05), and most participants reported no pain, demonstrating the effectiveness of the REFIX technology against dentin hypersensitivity. CONCLUSION: This clinical trial shows that the use of the phosphate-based desensitizing toothpaste containing REFIX technology significantly reduces dentin hypersensitivity after 1 week of consistent use. CLINICAL SIGNIFICANCE: The absence of pain, a desired clinical condition in patients with dentin hypersensitivity, was reached with the use of desensitizing toothpaste containing REFIX technology after 1 week of use. Such condition positively impacts quality of life, providing a healthier daily routine for patients.


Asunto(s)
Desensibilizantes Dentinarios , Sensibilidad de la Dentina , Pastas de Dientes , Arginina , Carbonato de Calcio , Desensibilizantes Dentinarios/uso terapéutico , Sensibilidad de la Dentina/tratamiento farmacológico , Sensibilidad de la Dentina/prevención & control , Método Doble Ciego , Femenino , Fluoruros , Humanos , Calidad de Vida , Fluoruro de Sodio , Cepillado Dental , Pastas de Dientes/uso terapéutico , Resultado del Tratamiento
17.
Am J Dent ; 33(5): 258-264, 2020 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-33017529

RESUMEN

PURPOSE: To compare the effectiveness in reducing plaque and gingivitis of a fluoride toothpaste with 20% baking soda and a fluoride toothpaste control. METHODS: 159 subjects, who met the entry criteria, participated in this single-center, double-blind, randomized, parallel-group clinical study. Gingival Index (MGI), Gingival Bleeding Index (GBI), and Plaque Index (PI) were assessed after 4, 8, and 12 weeks use of the assigned test or control toothpaste. After 12 weeks, participants resumed 4 weeks of their customary oral hygiene after which they were re-evaluated using the same measures. RESULTS: Both toothpastes statistically significantly reduced MGI, GBI, and PI versus baseline at all-time points. Brushing with the 20% baking soda toothpaste statistically significantly reduced MGI, PI, and GBI compared to the control toothpaste at all time points. After 12 weeks, the reductions in MGI, PI, and GBI were 12.6%, 9.6%, and 44.2%, respectively. After the 4-week customary oral hygiene period, the benefits of the study period had begun to diminish, but statistically significant reductions in MGI and GBI for the test versus control were still evident. This 3-month clinical study shows that brushing with fluoride toothpaste containing 20% baking soda reduces dental plaque and concurrently reduces gingival inflammation and bleeding compared to toothpaste with fluoride alone. CLINICAL SIGNIFICANCE: Fluoride toothpaste with 20% baking soda has the potential to offer multiple oral health benefits when used as an adjunct to regular tooth brushing and, therefore, may be confidently recommended to patients.


Asunto(s)
Placa Dental/prevención & control , Gingivitis/prevención & control , Índice de Placa Dental , Humanos , Bicarbonato de Sodio/uso terapéutico , Pastas de Dientes/uso terapéutico
18.
Am J Dent ; 33(5): 265-272, 2020 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-33017530

RESUMEN

PURPOSE: To compare the effectiveness in reducing plaque and gingivitis of two fluoride toothpastes containing baking soda (35% and 20%) with a fluoride toothpaste control. METHODS: 319 subjects, who met entry criteria, participated in this single-center, three-cell, double-blind, randomized, parallel-group clinical study. Gingival Index (MGI), Gingival Bleeding Index (GBI), and Plaque Index (PI) were assessed at baseline, and after 6 weeks, 3 and 6 months. RESULTS: All three toothpastes significantly (P< 0.0001) reduced MGI, GBI, and PI versus baseline, and the two baking soda toothpastes significantly (P< 0.0001) reduced MGI, GBI, and PI compared to the fluoride control, at all three time points. After 6 months use, the 35% and 20% baking soda toothpastes had reduced MGI, GBI and PI by 15.0%, 46.9%, and 18.3%, and 9.4%, 25.9%, and 12.4%, respectively, compared to the control. In addition, the 35% baking soda toothpaste had reduced (P≤ 0.0005) MGI, GBI, and PI by 6.2%, 28.4%, and 6.8%, respectively, compared to the 20% baking soda toothpaste. This clinical study showed that brushing with fluoride toothpastes containing baking soda at 35% and 20% reduces plaque, gingival inflammation and bleeding more effectively than regular fluoride toothpaste. Further, it showed that 35% baking soda toothpaste was more effective in reducing these parameters than 20% baking soda toothpaste. CLINICAL SIGNIFICANCE: Fluoride toothpastes containing 20% or more baking soda can provide significant and meaningful gingival health benefits when used regularly as an adjunct to tooth brushing.


Asunto(s)
Placa Dental/prevención & control , Gingivitis/prevención & control , Índice de Placa Dental , Humanos , Bicarbonato de Sodio , Pastas de Dientes
19.
J Evid Based Dent Pract ; 20(3): 101460, 2020 09.
Artículo en Inglés | MEDLINE | ID: mdl-32921380

RESUMEN

ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Network Meta-Analysis on the Effect of Desensitizing Toothpastes on Dentine Hypersensitivity. Hu ML, Zheng G, Lin H, Yang M, Zhang YD, Han JM. J Dent 2019;88:103170. SOURCE OF FUNDING: National Natural Science Foundation of China (81771119). TYPE OF STUDY/DESIGN: Systematic review with meta-analysis of data.


Asunto(s)
Desensibilizantes Dentinarios , Sensibilidad de la Dentina , China , Desensibilizantes Dentinarios/uso terapéutico , Humanos , Pastas de Dientes
20.
Medicine (Baltimore) ; 99(36): e21622, 2020 Sep 04.
Artículo en Inglés | MEDLINE | ID: mdl-32898997

RESUMEN

The objective of the study was to characterize self-reported oral hygiene practices among Mexican older adults aged ≥60 years, and to measure the association between frequency of tooth brushing and a set of sociodemographic, socioeconomic, and dental variables.We conducted a cross-sectional study of 139 older adults aged ≥60 years in Pachuca, Mexico. A questionnaire and a clinical dental examination were administered to identify specific variables. We determined frequency of tooth brushing (or cleaning of dentures or prostheses) and use of toothpaste, mouthwash, and dental floss among respondents. Non-parametric testing was performed for statistical analysis and a multivariate logistic regression model was generated with Stata 11 software to determine frequency of tooth brushing.In our study sample, 53.2% of participants reported brushing their teeth at least once a day, 50.4% always using toothpaste, 16.5% using mouthwash and 3.6% using floss for their oral hygiene. In general, younger and female respondents used oral hygiene aids more than the others. Our multivariate model yielded an association (P < .05) between tooth brushing at least once daily and the following variables: having functional dentition (OR = 12.60), lacking health insurance (OR = 3.72), being retired/pensioned (OR = 4.50), and suffering from a chronic disease (OR = 0.43).The older adults in our sample exhibited deficient oral hygiene behaviors. The results suggest certain socioeconomic inequalities in oral health. The findings of this study should be considered when designing dental care instructions for older adults.


Asunto(s)
Cepillado Dental/estadística & datos numéricos , Anciano , Anciano de 80 o más Años , Estudios Transversales , Dispositivos para el Autocuidado Bucal , Femenino , Humanos , Masculino , México/epidemiología , Persona de Mediana Edad , Antisépticos Bucales/administración & dosificación , Autoinforme , Factores Socioeconómicos , Pastas de Dientes/administración & dosificación
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