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1.
Bull Cancer ; 107(1): 113-128, 2020 Jan.
Artículo en Francés | MEDLINE | ID: mdl-31353136

RESUMEN

In the context of chronic myeloid leukemia (CML) resistant to tyrosine kinase inhibitors (TKIs), BCR-ABL1 tyrosine kinase domain (TKD) mutations still remain the sole biological marker that directly condition therapeutic decision. These recommendations aim at updating the use of BCR-ABL1 mutation testing with respect to new available therapeutic options and at repositioning different testing methods at the era of next generation sequencing (NGS). They have been written by a panel of experts from the French Study Group on CML (Fi-LMC), after a critical review of relevant publications. TKD mutation testing is recommended in case of treatment failure but not in case of optimal response. For patients in warning situation, mutation testing must be discussed depending on the type of TKI used, lasting of the treatment, kinetic evolution of BCR-ABL1 transcripts along time and necessity for switching treatment. The kind and the frequency of TKD mutations occasioning resistance mainly depend on the TKI in use and disease phase. Because of its better sensitivity, NGS methods are recommended for mutation testing rather than Sanger's. Facing a given TKD mutation, therapeutic decision should be taken based on in vitro sensitivity and clinical efficacy data. Identification by sequencing of a TKD mutation known to induce resistance must lead to a therapeutic change. The clinical value of testing methods more sensitive than NGS remains to be assessed.


Asunto(s)
Análisis Mutacional de ADN/métodos , ADN de Neoplasias/genética , Proteínas de Fusión bcr-abl/genética , Leucemia Mielógena Crónica BCR-ABL Positiva/genética , Mutación Missense , Mutación Puntual , Antineoplásicos/uso terapéutico , Dominio Catalítico , Toma de Decisiones Clínicas , ADN de Neoplasias/análisis , Resistencia a Antineoplásicos/genética , Sustitución de Medicamentos , Proteínas de Fusión bcr-abl/antagonistas & inhibidores , Secuenciación de Nucleótidos de Alto Rendimiento , Humanos , Leucemia Mielógena Crónica BCR-ABL Positiva/tratamiento farmacológico , Leucemia Mielógena Crónica BCR-ABL Positiva/enzimología , Biología Molecular , Dominios Proteicos , Inhibidores de Proteínas Quinasas/uso terapéutico , Rol
2.
Rev. cienc. cuidad ; 17(1): 123-131, 2020.
Artículo en Español | LILACS, COLNAL | ID: biblio-1051989

RESUMEN

La espiritualidad es un concepto que ha permeado el mundo académico, especialmente en los contextos de los cuidados en salud y particularmente en enfermería. Esta se ha asociado a situaciones tales como el afrontamiento de la muerte, al cuidado paliativo, a la vivencia de la cronicidad y a la adultez mayor. El presente texto aborda una reflexión a la luz de la literatura y la experiencia clínica acerca de la relación entre cuidado espiritual y el rol de la enfermería en la práctica en donde se brinda cuidado a las personas a través del ciclo vital. Se hace una aproximación al estado del arte y a los referentes relacionados con la delimitación del constructo cuidado espiritual, proporcionando un marco de referencia útil para la consulta académica y su inclusión en la práctica de la enfermería.


Spirituality is a concept which has permeated the academic world, especially in the contexts of health care, and particularly, nursing. This has been associated to situations such as facing death, palliative care, and living chronicity and adulthood. This text addresses a reflection, to the light of literature and clinical experience, relating to the relationship between spiritual care and the role of nursing in the practice, where care is provided for people throughout their life cycle. An approximation about the state of the art and the referring related to the delimitations of the spiritual care construct is made, providing a frame of reference that is useful for academic review and its inclusion in the nursing practice.


A espiritualidade é um conceito que tem permeado o mundo acadêmico, especialmente nos contextos dos cuidados na saúde e particularmente, na enfermagem. Têm se associado a situações como o afrontamento da morte, o cuidado paliativo, a viven cia da cronicidade e o envelhecimento. O presente texto faz uma abordagem reflexiva à luz da literatura e a experiência clínica, ao redor da relação entre o cuidado espiritual e o rol de enfermagem na prática, onde se presta cuidados as pessoas através do curso de vida. Faz uma aproximação ao existente e os referentes relacionados com a delimitação do constructo cuidado espiritual, proporcionando um marco de referencia útil para a consulta acadêmica e a inclusão da prática enfermeira.


Asunto(s)
Anciano , Espiritualidad , Rol , Familia , Atención de Enfermería
3.
Environ Technol ; 41(1): 109-116, 2020 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-29924699

RESUMEN

Low H2O2 utilization efficiency is the main problem when Fenton system was used to oxidize NO in flue gas. To understand the behaviour of the free radicals during NO oxidation process in Fenton system is crucial to solving this problem. The oxidation capacity of [Formula: see text] and [Formula: see text] on NO in Fenton system was compared and the useless consumption path of [Formula: see text] and [Formula: see text] that caused the low utilization efficiency of H2O2 were studied. A method to enhance the oxidation ability and H2O2 utilization efficiency by adding reducing additives in Fenton system was proposed. The results showed that both of [Formula: see text] and [Formula: see text] were active substances that oxidize NO. However, the oxidation ability of [Formula: see text] radicals was stronger. The vast majority of [Formula: see text] and [Formula: see text] was consumed by rapid reaction [Formula: see text] , which was the primary reason for the low utilization efficiency of H2O2 in Fenton system. Hydroxylamine hydrochloride and ascorbic acid could accelerate the conversion of Fe3+ to Fe2+, thereby increase the generation rate of ·OH and decrease the generation rate of [Formula: see text]. As a result, the oxidation ability and H2O2 utilization efficiency were enhanced.


Asunto(s)
Ácido Ascórbico , Peróxido de Hidrógeno , Radicales Libres , Oxidación-Reducción , Rol
4.
Bioresour Technol ; 296: 122375, 2020 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-31734063

RESUMEN

This study aims to assess the roles of different humin and heavy-metal resistant bacterial community from composting on heavy metal removal. The results showed that the concentration of Cu2+, Zn2+, Ni2+, Pb2+, Cr3+ and Cd2+ decreased with adding the compost-derived humin, but the removal rates were relatively low (<30% on average). The heavy metal resistant bacteria from composting have better metal binding capacities than humin, and the combined addition of humin and bacteria could further stimulate the biosorption of heavy metals with 60-80% removal of metals and improve the diversity and biomass of bacterial community. There was obviously increased synergy between the humin from maturity phase and bacteria for metal biosorption ("1 + 1 > 2"). Structural equation modeling showed that microbial biomass and humin humification are the key factors for the biosorption of heavy metals. Combining humin from maturity phase with heavy-metal resistant bacteria was suggested to control heavy metal pollution in composts.


Asunto(s)
Compostaje , Metales Pesados , Bacterias , Sustancias Húmicas , Rol , Suelo
5.
Int Endod J ; 53(1): 62-71, 2020 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-31411737

RESUMEN

AIM: To verify whether experimentally induced pulpitis activates the expression of transient receptor potential vanilloid type 1 (TRPV1) and c-Fos, both peripherally and centrally. METHODOLOGY: Acute pulpitis was induced in Sprague-Dawley rats via pulp exposure and application of complete Freund's adjuvant (CFA; n = 13). Saline-treated (n = 13) rats and rats that did not undergo tooth preparation (n = 13) served as control groups. Three days post-CFA or post-saline application, face grooming activity was recorded, and the rats were then euthanized to allow for immunohistochemical analysis of the trigeminal ganglion (TG) and spinal trigeminal nucleus. anova with Student's t-test for post-hoc analysis was used to quantify the differences in behavioural tests and immunohistochemical labelling (c-Fos and TRPV1) in TG amongst groups. Kruskal-Wallis test with Dunnett's test for post-hoc analysis was used to compare immunohistochemical labelling (c-Fos and TRPV1) in the brainstem amongst groups. RESULTS: Histological evidence of severe pulp inflammation was found, and there was a significant increase in pain-like behaviour (P < 0.05) in CFA-treated animals. C-Fos labelling and TRPV1 immunoreactivity in the TG were significantly higher (both P < 0.05) in the CFA group than in the control groups. In the spinal trigeminal nucleus, the immunoreactivity for c-Fos was absent in the intermediate region (trigeminal subnucleus interpolaris) in all animals, with comparable expression of TRPV1 amongst all groups. In contrast, neurons in the trigeminal subnucleus caudalis (TSC) exhibited significant c-Fos immunoreactivity in the CFA group (P = 0.0063). The expression of TRPV1 did not differ amongst the three groups, but the superficial laminae of the TSC exhibited significantly greater expression of TRPV1 than did the deep layers (P = 0.0014). CONCLUSIONS: Following acute pulp inflammation, the TRPV1 channel was significantly involved in nociceptive signal processing in the peripheral nervous system, but not in the CNS. Because pulpitis induced some neuronal activation at the brainstem levels, further studies are needed to identify additional transducers that mediate signal transmission from pulpal afferents to their central targets.


Asunto(s)
Pulpa Dental , Ganglio del Trigémino , Animales , Tronco Encefálico , Inflamación , Proteínas Proto-Oncogénicas c-fos , Ratas , Ratas Sprague-Dawley , Rol
6.
J Contemp Dent Pract ; 20(8): 970-973, 2019 Aug 01.
Artículo en Inglés | MEDLINE | ID: mdl-31797856

RESUMEN

AIM: To evaluate the salivary lactate dehydrogenase (LDH) levels in clinico-pathologically confirmed oral submucous fibrosis (OSMF), oral cancer and clinically diagnosed tobacco pouch keratosis patients. MATERIALS AND METHODS: A prospective, comparative study was carried out in a tertiary healthcare centre located in Loni from October 2013 to January 2014. A total of 120 patients were separated into 4 groups depending upon the clinical diagnosis as follows. Group I: healthy control (with no addictions and diseases). Group II: oral cancer. Group III: oral submucous fibrosis. Group IV: habitual tobacco chewers (tobacco addiction without any disease). Substantiation was done using biopsy. The samples were inspected for salivary LDH levels by the technique in line with the recommendations of the International Federation of Clinical Chemistry with the help of Erba Chem semi auto analyser. RESULTS: The mean salivary LDH levels in the control, oral cancer OSMF and habitual tobacco chewer group were 86.12 ± 7.05 IU/L, 592.09 ± 28.57 IU/L, 350.43 ± 5.90 IU/L and 125.19 ± 13.42 IU/L, respectively. Out of 4 groups, LDH activity was increased in saliva of patients with tobacco pouch keratosis, OSMF, and oral cancer consistently. Notable difference was found in the mean salivary levels of the above groups. Results were subjected to appropriate statistical analysis: one-way ANOVA, Student's unpaired t test for group-wise comparison followed by post hoc Tukey's test. CONCLUSION: We observed congruous higher levels of salivary LDH in oral precancer and cancer, and hence it could be a future marker.


Asunto(s)
Neoplasias de la Boca , Fibrosis de la Submucosa Bucal , Biomarcadores , Humanos , L-Lactato Deshidrogenasa , Estudios Prospectivos , Rol , Tabaco
7.
J Contemp Dent Pract ; 20(8): 987-993, 2019 Aug 01.
Artículo en Inglés | MEDLINE | ID: mdl-31797859

RESUMEN

Since a long time, the preservation of the socket is emphasized for various reasons. Many studies have suggested the ridge preservation through socket grafting using various bone graft substitute materials (GSMs). But none of the studies suggested the material of choice for the grafting. So, the systematic review was planned to analyze the outcomes of synthetic hydroxyapatite (SHA) graft material for socket preservation. The review was aimed to determine the existing evidence for the use of SHA GSM for grafting and its usefulness. MATERIALS AND METHODS: The literature search was performed for the studies published in the English language independently by all four authors (search team) in the Medline database through the PubMed search engine for the past 5 years. The study involved predetermined inclusion and exclusion criteria for the search. The final lists of clinical trials were analyzed to determine the existing evidence and suggested the mechanism of action. REVIEW RESULTS: The search resulted in 117 titles. After application of inclusion and exclusion criteria, a total of seven studies were found eligible for this systematic review. Out of seven, two studies were found eligible for meta-analysis whereas remaining included for the systematic review. CONCLUSION: The meta-analysis favors socket grafting compared to control in terms of preservation of existing bone height and width. The SHA grafting showed successful bone regeneration with less connective tissue component. The histomorphometric evaluation showed a good bone regeneration associated with SHA than xenograft. Within the limitations of this meta-analysis, the synthetic GSM can be used for socket grafting. CLINICAL SIGNIFICANCE: In the wake of increasing graft materials in the market and different origin raw material sources for the preparation of graft materials, clinicians are in dilemma for selection and its use. The success of grafting depends on the selection of appropriate material with a suitable calcium/phosphate (Ca/P) ratio. The review provided available evidence for the use of SHA.


Asunto(s)
Aumento de la Cresta Alveolar , Durapatita , Regeneración Ósea , Trasplante Óseo , Xenoinjertos , Rol , Extracción Dental , Alveolo Dental
8.
Science ; 366(6470)2019 12 06.
Artículo en Inglés | MEDLINE | ID: mdl-31806787

RESUMEN

Hesselmann et al question one of our conclusions: the suppression of Fermi velocity at the Gross-Neveu critical point for the specific case of vanishing long-range interactions and at zero energy. The possibility they raise could occur in any finite-size extrapolation of numerical data. Although we cannot definitively rule out this possibility, we provide mathematical bounds on its likelihood.


Asunto(s)
Electrones , Rol
10.
Hand Clin ; 35(4): 449-455, 2019 11.
Artículo en Inglés | MEDLINE | ID: mdl-31585606

RESUMEN

Global outreach in hand surgery can be exceptionally rewarding for volunteers and their organizations, patients and their communities, and the host medical community. Success can be defined by individual cases that restore function and provide opportunities for a patient and family to contribute to society; however, the broader missions of medical collaboration, education, cultural exchange, and personal growth are critical factors toward building trust and establishing continuity of care for long-term success. Each outreach site and brigade encounters challenges; however, careful planning facilitates optimal conditions and reasonable expectations for enhancing outcomes.


Asunto(s)
Misiones Médicas/organización & administración , Ortopedia , Comunicación , Continuidad de la Atención al Paciente , Competencia Cultural , Documentación/normas , Personal de Salud/educación , Humanos , Consentimiento Informado , Registros Médicos , Evaluación de Necesidades , Grupo de Atención al Paciente/organización & administración , Educación del Paciente como Asunto , Pase de Guardia , Mejoramiento de la Calidad , Rol , Seguridad , Rondas de Enseñanza , Confianza
11.
Lakartidningen ; 1162019 Oct 07.
Artículo en Sueco | MEDLINE | ID: mdl-31593289

RESUMEN

The medical and nursing care of preterm infants has improved over the last decades, including the involvement of parents in the daily care. Previously parents could only visit a few scheduled hours per day but today most neonatal units in Sweden strive to let the parents be the primary caregivers, with the right to stay at the unit during the entire hospitalization period. Despite this development, there is still need for a number of improvements, not only in the neonatal care but also during the complicated pregnancy.


Asunto(s)
Cuidado Intensivo Neonatal/organización & administración , Responsabilidad Parental , Nacimiento Prematuro , Rol , Lactancia Materna , Continuidad de la Atención al Paciente , Padre , Femenino , Humanos , Recién Nacido , Recien Nacido Prematuro , Servicios de Salud Materna/organización & administración , Madres , Alta del Paciente , Educación del Paciente como Asunto , Embarazo , Apoyo Social , Suecia
12.
Res Dev Disabil ; 94: 103455, 2019 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-31499379

RESUMEN

BACKGROUND: Popular indivuals are usually academically high achiveving and also often leaders. Children with developmental disabilities are usually not popular among their peers. In dyadic cooperative tasks, the popular member is often the leader, as shown by self-reports and observational research. It is unknown whether this macro-level behaviour is reflected in micro-level synchronisation patterns of the movements of dyads who are engaged in a cooperative task. AIMS: The goal of the present study was to investigate whether popularity differentially affected the leading-following behaviour of dyads consisting of children with and without developmental disabilities. METHODS AND PROCEDURES: Children with (n = 106) and without (n = 183) developmental disabilities performed a tangram puzzle task individually and cooperatively. While performing the task, they stood on a Nintendo Wii Balance Board that registered their postural sway. OUTCOMES AND RESULTS: Although we found some similarities between dyads with and without a developmental disability based on both popularity and task performance, the most striking difference occurred in low performing dyads. In those, dyads with a developmental disability had no clear leader or follower. CONCLUSION: Especially in dyads with developmental disabilities it is important that there are clear roles, since the worst performance was observed when roles were absent.


Asunto(s)
Conducta Infantil/psicología , Discapacidades del Desarrollo/psicología , Liderazgo , Rol , Deseabilidad Social , Niño , Conducta Cooperativa , Femenino , Procesos de Grupo , Humanos , Masculino , Habilidades Sociales , Análisis y Desempeño de Tareas
13.
Prog Cardiovasc Dis ; 62(4): 358-363, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31377224

RESUMEN

Patients with diabetes mellitus (DM) often exhibit a complex coronary anatomy, making coronary revascularization challenging. Coronary artery bypass grafting surgery (CABG) is currently considered the preferred revascularization method in patients with DM and multivessel disease. Percutaneous coronary intervention (PCI) has advanced with new stent generations having been developed in the recent years, but they have not yet been adequately compared against CABG in the population with DM. Comorbidities, such as renal disease and heart failure, lead to worse prognosis following a revascularization procedure and require especial consideration when choosing between CABG versus PCI. The presence of significant left main disease may also impose additional challenges to coronary revascularization, particularly when accompanied by the involvement of multivessel disease. Most of the evidence regarding revascularization in patients with DM is compiled from studies enrolling patients with stable ischemic heart disease, and trials with patients in the acute coronary syndrome setting are lacking.


Asunto(s)
Puente de Arteria Coronaria/métodos , Enfermedad de la Arteria Coronaria/epidemiología , Enfermedad de la Arteria Coronaria/cirugía , Diabetes Mellitus Tipo 2/epidemiología , Angiopatías Diabéticas/cirugía , Intervención Coronaria Percutánea/métodos , Anciano , Comorbilidad , Puente de Arteria Coronaria/efectos adversos , Enfermedad de la Arteria Coronaria/diagnóstico por imagen , Diabetes Mellitus Tipo 2/diagnóstico , Diabetes Mellitus Tipo 2/tratamiento farmacológico , Angiopatías Diabéticas/diagnóstico por imagen , Angiopatías Diabéticas/epidemiología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Revascularización Miocárdica/métodos , Intervención Coronaria Percutánea/efectos adversos , Pronóstico , Medición de Riesgo , Rol , Tasa de Supervivencia , Resultado del Tratamiento
15.
Int Heart J ; 60(5): 1077-1082, 2019 Sep 27.
Artículo en Inglés | MEDLINE | ID: mdl-31447466

RESUMEN

Patients with ST-segment elevation myocardial infarction (STEMI) who are treated by primary percutaneous coronary intervention (PPCI) have an increased risk of developing contrast-induced nephropathy (CIN) when compared with patients undergoing elective percutaneous coronary intervention (PCI). However, CIN prevention measures are less frequently applied in PPCI than in elective PCI. At present, no preventive strategy has been recommended by the current guidelines for patients with STEMI undergoing PPCI.Published research was scanned by formal searches of electronic databases (PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials) from 1966 to July 2018. Internet-based sources of information on the results of clinical trials in cardiology were also searched.A total of three randomized trials involving 924 patients were included in the present meta-analysis, of whom 462 received hydration with isotonic saline (hydration group) and 462 received no hydration (control group). Periprocedural hydration with isotonic saline was associated with a significant decrease in the rate of CIN (16.9% in the hydration group versus 26.4% in the control group; summary risk ratio: 0.64, 95% confidence interval: 0.50-0.82, P = 0.0005). There was no difference in the rate of postprocedural hemodialysis or death between the groups.Intravenous saline hydration during PPCI reduced the risk of CIN without significantly altering the rate of requirement for renal replacement therapy or mortality.


Asunto(s)
Lesión Renal Aguda/inducido químicamente , Lesión Renal Aguda/terapia , Medios de Contraste/efectos adversos , Fluidoterapia/métodos , Intervención Coronaria Percutánea/métodos , Infarto del Miocardio con Elevación del ST/terapia , Lesión Renal Aguda/prevención & control , Anciano , Angiografía Coronaria/efectos adversos , Angiografía Coronaria/métodos , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Intervención Coronaria Percutánea/efectos adversos , Ensayos Clínicos Controlados Aleatorios como Asunto , Medición de Riesgo , Rol , Infarto del Miocardio con Elevación del ST/diagnóstico por imagen , Infarto del Miocardio con Elevación del ST/mortalidad , Análisis de Supervivencia , Resultado del Tratamiento
16.
Acta Psychol (Amst) ; 199: 102922, 2019 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-31446312

RESUMEN

The effect of forgetting cues on maintenance rehearsal in item-method directed forgetting (DF) paradigm was explored from behavioral and electrophysiological evidence. In Experiment 1, maintenance rehearsal was induced by a maintenance cue. Specifically, after the studied word, a maintenance (M) cue was presented before the presentation of a remembering/forgetting cue. When an M cue appeared, participants were required to wait for the following remembering (M-R) or forgetting (M-F) cue to determine whether the word needs to be remembered or not, and words were kept in short-term memory with maintenance rehearsal until the presentation of M-R/M-F cues. Four conditions were utilized: maintain-remembering (M-R), maintain-forgetting (M-F), maintenance (M), and forgetting (F). The results showed that, 1) superior recognition was found for the M-R relative to the M-F words, revealing a typical DF effect; 2) No recognition difference was found between M and M-F words, indicating that M-F cues showed little effect in promoting forgetting; 3) Inferior recognition was found for F than M words, indicating that the maintenance rehearsal might cease or be reduced by the presentation of F cues. In Experiment 2, event related potentials time-locked to cue (M-R, M-F, M, and F cues) onset during study phase. An enhanced fronto-central P3a component was evoked for F relative to M cues, indicating a more intensive attention orienting or attentional inhibition process triggered by F cues. These results demonstrated that forgetting cues might trigger an inhibition process to terminate the maintenance rehearsal process.


Asunto(s)
Atención/fisiología , Señales (Psicología) , Recuerdo Mental/fisiología , Estimulación Luminosa/métodos , Rol , Adolescente , Adulto , Femenino , Humanos , Masculino , Memoria a Corto Plazo/fisiología , Orientación Espacial/fisiología , Distribución Aleatoria , Adulto Joven
18.
Arch. med. deporte ; 36(192): 208-214, jul.-ago. 2019. tab, graf
Artículo en Español | IBECS | ID: ibc-185176

RESUMEN

Objetivos: Determinar el tipo de personal médico, las prioridades y actividades para la protección y promoción de la salud de las Federaciones Nacionales de Natación (FNN) según su nivel económico y determinar si aplicaban los programas relacionados con la salud de la Federación Internacional de Natación (FINA).Método: Se realizó un estudio descriptivo transversal mediante una encuesta confidencial distribuida a las 208 FNN adscritas a la FINA. La encuesta fue validada y se obtuvo su fiabilidad estadística (coeficiente α de Cronbach de 0,8642 para n = 15). Las FNN se dividieron según su nivel económico en FNN de países desarrollados (n=66) y FNN de países en desarrollo (n = 142) siguiendo la clasificación de la Organization for Economic Cooperation and Development (2016). Análisis: Se realizó una comparación estadística de las medias mediante la prueba U de Mann-Whitney. Resultados: Respondieron 80 FNN en desarrollo (56,3 %) y 55 desarrolladas (83,6 %). Hubo diferencias en la presencia de fisioterapeutas (FNN en desarrollo: 31,2%, desarrolladas: 58,1%, p < 0,005) y psicólogos (11,2% vs 21,8%; p = 0,096). La máxima prioridad para ambos grupos fue el Máximo rendimiento de los nadadores de élite, aunque Aumentar el número de nada-dores de élite era de mayor importancia para las FNN en desarrollo (4,1 vs 3,95; p < 0.05). Los Programas de Prevención de ahogamiento fueron los más frecuentes en ambos grupos, pero con diferencias significativas entre ellos (FNN En desarrollo: 58,7% vs FNN Desarrolladas: 74,5%; p = 0,058). Conclusiones: Las FNN no disponían del personal necesario para promover la salud de sus nadadores. La mayor prioridad de las FNN en desarrollo era Aumentar el número de atletas de élite, pero tenían bajos niveles de Prevención de lesiones, Vuelta a competir tras una lesión y de Exámenes médicos preparticipación, aunque en las FNN desarrolladas también eran bajos. La Prevención de ahogamiento fueron los programas más frecuentes pero la Salud de la población en general, la del atleta recreativo y el "Deporte Seguro" (sin acoso sexual) eran cuestiones de baja prioridad para todas


Purposes: To determine the profile of the medical personnel, the priorities and the activities/ researches of the National Swimming Federations of Developing and Developed countries with respect to the athletes' health protection and the promotion of health in the general population. Method: A descriptive transversal study through a confidential survey that was circulated to the 208 FINA National Member Federations. A statistical validity and reliability was obtained (Cronbach α coefficient of 0.8642 for n = 15). The NFs were divided based on their economic level, NFs of developed (n = 66) and developing countries (n = 142) following the classification of the Organization for Economic Co-operation and Development, (2016). Analysis: A statistic comparison of measures with the test U of Mann- Whitney was executed. Results: 80 of the NFs from developing countries (56.3%) responded and 55 NFs from developed countries (83.6%). Evident differences were found in Presence of physiotherapists (Developing NFs: 31.2%, Developed NFs: 58.1%; p<0.005) and psycho-logists (11.2% vs 21.8%; p = 0.096). Top priority for both groups was Performance of the elite athletes, however Increasing the numbers of elite athletes was of major importance for the Developing NFs (4.1 vs 3.95, p < 0.05). The programs based around drowning prevention are the most prevalent of the programs run by both (58.7% vs 74.5%; p = 0.058). Conclusion: The NFs did not have the necessary personnel to promote the health of their athletes. Top priority for the Developed NFs was to Increase the numbers of elite athletes but they have low levels of Prevention of injuries programs. Coming back after an injury and Medical examination preparation were also low in Developed and in Developing NFs. Prevention of drowning program was the most frequent program/activity for health of general population, for the recreational athlete and "Save Sport" (without sexual abuse) they were questions of low priority for all of them


Asunto(s)
Natación/normas , Promoción de la Salud/normas , Países Desarrollados , Países en Desarrollo , Organizaciones de Normalización Profesional/normas , Deportes/normas , Natación/legislación & jurisprudencia , Promoción de la Salud/organización & administración , Federación para Atención de Salud/normas , Estudios Transversales , Estadísticas no Paramétricas , Rol
19.
Muscle Nerve ; 60(4): 419-424, 2019 10.
Artículo en Inglés | MEDLINE | ID: mdl-31298728

RESUMEN

INTRODUCTION: Limb-girdle muscular dystrophy (LGMD) consists of over 30 genetic conditions with varying clinical phenotypes primarily affecting pelvic girdle, shoulder girdle, and other proximal limb muscles. Studies focusing on the physical, mental, and social effects of this disease from the patient's perspective are limited. METHODS: Adults with LGMD were interviewed and asked to identify issues that have the greatest impact on their quality of life. Each interview was recorded, transcribed, coded, and analyzed. RESULTS: Participants provided 1385 direct quotes. One hundred sixty-five potential symptoms of importance were identified and grouped into 15 larger themes. The most frequently reported themes included limitations with mobility, difficulty performing activities, social role limitations, and emotional distress. DISCUSSION: There are multiple symptoms that alter the lives of adults with LGMD. These affect their physical, emotional, and social health, and may be amenable to medical intervention.


Asunto(s)
Actividades Cotidianas , Limitación de la Movilidad , Distrofia Muscular de Cinturas/fisiopatología , Distrofia Muscular de Cinturas/psicología , Participación Social , Adulto , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Investigación Cualitativa , Rol , Adulto Joven
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