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1.
Niger J Clin Pract ; 24(1): 28-37, 2021 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-33473022

RESUMEN

Background: Metabolic syndrome (MetS) has become an issue in the public health discipline. Aims: The primary aim of this study is to assess the potential determinants for both knowledge level of metabolic syndrome and health literacy (HL) level among the adult population. The second purpose of this study is to show whether there is a relationship between the MetS knowledge level and the HL level in western Turkey. Methods: This cross-sectional study was conducted between October 10, 2017 and November 15, 2017 in western Turkey. The participants of the study were adult population who applied to seven "family health centers". The MetS knowledge level was measured with the Metabolic Syndrome Knowledge Level Scale (MetS-KS). HL level was measured with the HLS-EU-Q16. A General Linear Model was constructed to evaluate the relationship between MetS-KS scores and HLS-EU-Q16 scores. For statistical significance, P < 0.05 was accepted. Results: Younger age, having higher education level, being single, having a high family income, not having a chronic disease, doing regular physical activity, viewing television less than 3 hours a day, previous measurement of waist circumference, previous attempts to lose weight, not being abdominally obese, not being at risk for hypertension and not having optimal body mass index (BMI) were associated with high HL levels (P < 0.05 for each one). According to the general linear model, the level of HL was not related to the level of MetS knowledge level (P > 0.05). Conclusions: Younger age, having a high educational level, high socioeconomic level and positive health behaviors were related with both MetS knowledge level and HL level. However, there was no direct relationship between MetS knowledge level and HL level.


Asunto(s)
Alfabetización en Salud , Síndrome Metabólico , Adulto , Índice de Masa Corporal , Estudios Transversales , Humanos , Síndrome Metabólico/epidemiología , Encuestas y Cuestionarios , Turquia/epidemiología
2.
Orv Hetil ; 162(5): 185-191, 2021 01 31.
Artículo en Húngaro | MEDLINE | ID: mdl-33517332

RESUMEN

Összefoglaló. Bevezetés: Krónikus obstruktív tüdobetegségben (COPD) az obesitas mellett a csökkent fizikai aktivitás nagymértékben fokozza a metabolikus szindróma kialakulásának valószínuségét. Célkituzés: Kutatásunk célja volt felmérni a metabolikus szindróma prevalenciáját COPD-ben, valamint azt, hogy milyen mértékben függ össze az életkorral, a nemmel, a társbetegségekkel, a tüdofunkció károsodásának mértékével, a tápláltsági állapottal, a fizikai terhelhetoséggel és az életminoséggel. Módszer: Keresztmetszeti vizsgálatot végeztünk az Országos Korányi Pulmonológiai Intézet Légzésrehabilitációs Osztályán fekvo betegek körében 2019. július 1. és december 31. között. A véletlenszeruen kiválasztott 300, 40 év feletti betegnek ismertük az antropometriai, légzésfunkciós vizsgálati eredményét és laboratóriumi paramétereit. Adatokat gyujtöttünk a dohányzási szokásokról, az elozo évi exacerbatiók számáról és a kortikoszteroidok használatáról is. Az életminoség mérésére a betegségspecifikus Szent György-féle Légzési Kérdoív magyar nyelvre validált változatát használtuk. A metabolikus szindrómát a Nemzetközi Diabetes Szövetség kritériumai alapján határoztuk meg. Eredmények: A metabolikus szindróma a betegek 72%-ánál fordult elo, férfi: 65,9% no: 77,2% (p = 0,031). A metabolikus szindrómás betegek esetében rövidebb 6 perces sétatávolságot mértünk ([m] 250 [150-330] vs. 295 [162-360]; p = 0,384), és szignifikánsan több volt az elozo évi exacerbatiók száma (3 [0-6] vs. 1 [1-2]; p<0,001) a nem metabolikus szindrómás betegekhez képest. A BMI-re történo stratifikáció után a metabolikus szindróma jelenléte nagyobb volt BMI≥25 kg/m2 esetén. A hasi elhízás, a magas vérnyomás, a hyperlipidaemia és a hyperglykaemia szignifikánsan gyakoribb volt BMI≥25 kg/m2 esetén (p<0,001). Következtetés: Eredményeink azt sugallják, hogy a metabolikus szindrómás betegekben megno az együttes morbiditási index, különösen azok körében, akik túlsúlyosak vagy elhízottak. Ezért a COPD-s betegekben nagyon fontos idoben felismerni és megfeleloen kezelni a metabolikus szindrómát. Orv Hetil. 2021; 162(5): 185-191. INTRODUCTION: Both obesity and the lack of physical activity among chronic obstructive pulmonary disease (COPD) patients increase the risk of developing metabolic syndrome. OBJECTIVE: The goal of our study was to assess the prevalence of metabolic syndrome among COPD patients and to examine its correlation with age, gender, comorbidities, lung function values, nutritional status, exercise capacity, and quality of life. METHOD: A cross-sectional study was performed at the Department of Pulmonary Rehabilitation of the Hungarian National Korányi Institute for Pulmonology between July 1st and December 31st, 2019. A total of 300 patients aged over 40 were selected at random. Anthropometric data were collected along with lung function values, laboratory parameters, smoking status, the number of exacerbations in the previous year, and the use of corticosteroids. Quality of life was measured by the validated Hungarian, COPD-specific Saint George Respiratory Questionnaire. Metabolic syndrome was defined according to the International Diabetes Federation criteria. RESULTS: Metabolic syndrome affected 72% of COPD patients (male: 65.9%, female 77.2%; p = 0.031). In patients with metabolic syndrome, shorter 6-minute walking distance was measured ([m] 250 [150-330] vs. 295 [162-360]; p = 0.384) and the number of exacerbations in the previous year was significantly higher (3 [0-6] vs. 1 [1-2]; p<0.001) compared to patients with no metabolic syndrome. After stratification for BMI, metabolic syndrome was more frequent in the case of BMI≥25 kg/m2. Central adiposity, hypertension, hyperlipidemia, and hyperglycemia were also significantly more frequent among patients with BMI≥25 kg/m2 (p<0.001). CONCLUSION: Our results suggest that the co-morbidity index increases in patients with metabolic syndrome, especially in overweight or obese patients. Therefore, early detection and appropriate treatment of metabolic syndrome in patients with COPD is very important. Orv Hetil. 2021; 162(5): 185-191.


Asunto(s)
Síndrome Metabólico/epidemiología , Obesidad/epidemiología , Enfermedad Pulmonar Obstructiva Crónica/epidemiología , Calidad de Vida , Anciano , Estudios Transversales , Femenino , Humanos , Hungría/epidemiología , Masculino , Encuestas y Cuestionarios
3.
J Occup Health ; 63(1): e12188, 2021 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-33469969

RESUMEN

OBJECTIVES: The cross-sectional study aimed to analyze the association between burnout, work-related factors, and metabolic syndrome (Mets) in nurses from several departments of a tertiary hospital in Taiwan. Exploring biomarkers could provide for prevention. METHODS: Demographic data were obtained through a written questionnaire and include the following information: gender, age, education level, psychosocial and work situations, such as departments, working hours, work shift, depression, and sleep time. Burnout was evaluated according to the Chinese Burnout inventory, Mets was evaluated according to the criteria of the National Cholesterol Education Program of Taiwan-Treatment Panel for Adults III (NCEP-ATP III). RESULTS: A total of 1758 nurses participated with a median age of 35.2 years. The prevalence of burnout and Mets was 6.4% and 13.84%, respectively. The results showed that burnout induced higher risk of Mets, odds ratio (OR) 1.70 (95% confidence interval, 1.04-3.05). Other factors, such as out-patient nurses, seniority (4-10 and >10 years), working hours (51-59 h/wk), nigh shift, Brief Symptom Rating Scale-5 (score 10-14 and ≧15), poor self-rated health status, and inadequate sleep time, led to higher risk of Mets. Biomarkers research showed that Glycated hemoglobin (Hba1c) was significantly associated with burnout nurses (OR = 24.72, P < .001), but thyroid-stimulating hormone and free thyroxin were not. CONCLUSIONS: Results suggested positive associations between burnout and Mets in nurses. For nurses with higher seniority, long hours of work, night shifts, poor physical and mental conditions, and poor lifestyle habits in different departments, strategies are needed to prevent burnout and Mets.


Asunto(s)
Agotamiento Profesional/epidemiología , Síndrome Metabólico/epidemiología , Personal de Enfermería en Hospital , Adulto , Biomarcadores/análisis , Estudios Transversales , Femenino , Humanos , Masculino , Prevalencia , Factores de Riesgo , Encuestas y Cuestionarios , Taiwán/epidemiología
4.
Curr Probl Cardiol ; 46(4): 100737, 2021 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-33412349

RESUMEN

BACKGROUND: The COVID-19 pandemic's mental health consequences remain unknown. AIM: To assess the mental health status of ambulatory cardiometabolic patients during COVID-19 pandemic lockdown in Spanish speaking Latin American countries. METHODS: Cardiometabolic patients without COVID-19 evidence in 13 Latin American countries answered a survey between June 15th and July 15th, 2020. The Diagnosis Manual of Mental Disorders fifth edition was used to identify the presence of major depressive symptoms. RESULTS: The sample included 4216 patients, 1590 (37.71%; IC95% 36.24-39.19) were considered suffering major depression. Female gender, consuming ≥5 medications day, physical activity <100 minutes weekly, low fruits and vegetables intake, poor treatment adherence, reduced food consumption were independently associated to the presence of major depressive symptoms. CONCLUSIONS: The CorCOVID Latam Psy study showed that one-third of the Latin American Spanish speaking population is suffering from major depressive symptoms during the COVID-19 outbreak.


Asunto(s)
Enfermedades Cardiovasculares/epidemiología , Depresión/epidemiología , Trastorno Depresivo Mayor/epidemiología , Diabetes Mellitus/epidemiología , Síndrome Metabólico/epidemiología , Adulto , Anciano , Enfermedades Cardiovasculares/psicología , Enfermedad de la Arteria Coronaria/epidemiología , Enfermedad de la Arteria Coronaria/psicología , Depresión/psicología , Trastorno Depresivo Mayor/psicología , Diabetes Mellitus/psicología , Dieta/estadística & datos numéricos , Dislipidemias/epidemiología , Dislipidemias/psicología , Ingestión de Alimentos , Ejercicio Físico/psicología , Femenino , Frutas , Insuficiencia Cardíaca/epidemiología , Insuficiencia Cardíaca/psicología , Humanos , Hipertensión/epidemiología , Hipertensión/psicología , América Latina/epidemiología , Masculino , Salud Mental , Síndrome Metabólico/psicología , Persona de Mediana Edad , Factores Sexuales , Accidente Cerebrovascular/epidemiología , Accidente Cerebrovascular/psicología , Encuestas y Cuestionarios , Cumplimiento y Adherencia al Tratamiento/psicología , Cumplimiento y Adherencia al Tratamiento/estadística & datos numéricos , Verduras
5.
Artículo en Inglés | MEDLINE | ID: mdl-33401397

RESUMEN

Metabolic syndrome is a group of metabolic risk factors whose combination significantly contributes to the development of the risk of cardiovascular disease, diabetes, stroke, some cancers and is a clear indicator of morbidity rate. The aim of this study was to identify physical activity programs that can successfully influence the reduction of risk factors in metabolic syndrome of the elderly. Subjects were aged between 60 and 80 years, had three of five signs of metabolic syndrome, and were randomly divided into three groups of 20 subjects. The first group conducted a continuous cycling ergometer (55% VO2max), the second group a physical activity strength program and the third was a control group. Before and after the experimental treatment body composition, biochemical parameters, functional parameters, cardiovascular functions, metabolic and hematological system were determined. Significant differences between control and experimental groups were determined using MANOVA. The training effects of the experimental and control groups were determined using the ANOVA for repeated measurements with Bonfferoni correction. The results showed that a physical activity program of strength has a better effect on disease regulation in the elderly with metabolic syndrome than a moderate-intensity physical activity program which also has a significant change but in less variables.


Asunto(s)
Ejercicio Físico , Síndrome Metabólico , Anciano , Anciano de 80 o más Años , Humanos , Síndrome Metabólico/epidemiología , Persona de Mediana Edad , Factores de Riesgo
6.
Esc. Anna Nery Rev. Enferm ; 25(1): e20200055, 2021. tab, graf
Artículo en Portugués | LILACS, BDENF - Enfermería | ID: biblio-1114764

RESUMEN

RESUMO Objetivo avaliar a síndrome metabólica e o risco cardiovascular de idosos hipertensos atendidos na atenção primária. Métodos estudo transversal realizado com 154 idosos hipertensos de uma Unidade Básica de Saúde do Distrito Federal. Um instrumento estruturado investigou o perfil dos idosos. Para a classificação da síndrome metabólica, consideraram-se os critérios propostos pela National Cholesterol Education Program - Adult Treatment Panel III. Para análise do risco cardiovascular, utilizou-se o escore de risco de Framingham. Foi realizada análise estatística e inferencial com a utilização da ANOVA, teste qui-quadrado e exato de Fisher, além da odds ratio e seu intervalo de confiança de 95% para estimar o risco cardiovascular entre os grupos. Resultados 64,9% dos idosos hipertensos eram obesos. Síndrome metabólica foi evidenciada em 70,8%. Observou-se que 27,2% apresentaram baixo, 46,8% moderado e 26,0% elevado risco cardiovascular, sendo que o sexo feminino e a idade avançada influenciaram negativamente o risco. Idosos com síndrome metabólica apresentaram 7,19 vezes mais chances de terem elevado risco cardiovascular. Considerações finais e implicações para a prática os idosos hipertensos apresentaram uma elevada prevalência de síndrome metabólica que aumentou significativamente o risco cardiovascular. Este resultado possibilita um melhor planejamento da assistência de enfermagem pelo enfermeiro da atenção primária à saúde.


RESUMEN Objetivo evaluar el síndrome metabólico y el riesgo cardiovascular de pacientes hipertensos de la tercera edad tratados en la atención primaria. Métodos estudio transversal realizado con 154 personas de la tercera edad hipertensas de una Unidad Básica de Salud del Distrito Federal. Se investigó el perfil de estas personas a través de un instrumento estructurado. Para clasificar el síndrome metabólico se utilizaron los criterios propuestos por el National Cholesterol Education Program - Adult Treatment Panel III. Para analizar el riesgo cardiovascular, se utilizó el escore de riesgo de Framingham. El análisis estadístico e inferencial se realizó mediante ANOVA, chi-cuadrado y la prueba exacta de Fisher, además de la odds ratio y su intervalo de confianza del 95% para estimar el riesgo cardiovascular entre los grupos. Resultados el 64,9% de las personas hipertensas de la tercera edad eran obesas. El síndrome metabólico se observó en el 70,8% de los casos. Se pudo observar que el 27,2% eran de riesgo cardiovascular bajo, 46,8% moderado y 26,0% alto, siendo que el sexo femenino y la edad avanzada influencian el aumento del riesgo. Las personas mayores de edad poseen 7,19 veces más probabilidades de tener un alto riesgo cardiovascular. Consideraciones finales e implicaciones para la práctica los pacientes hipertensos de edad avanzada tenían una prevalencia elevada de síndrome metabólico que aumentaba, considerablemente, el riesgo cardiovascular. Este resultado permite una mejor planificación de la atención de enfermería por parte de las enfermeras en la atención primaria de la salud.


ABSTRACT Objective To evaluate metabolic syndrome and cardiovascular risk for hypertensive elderly patients treated in primary care. Methods A cross-sectional study carried out with 154 hypertensive elderly from a Basic Health Unit in the Federal District. A structured instrument investigated the profile of the elderly. For classifying the metabolic syndrome, the criteria proposed by the National Cholesterol Education Program - Treatment Panel for Adults III were considered. For cardiovascular risk analysis, the Framingham risk score was used. Statistical and inferential analysis was performed using ANOVA, chi-square test and Fisher's exact test, in addition to Odds Ratio and its 95% confidence interval to estimate cardiovascular risk among the groups. Results 64.9% of the hypertensive elderly were obese. Metabolic syndrome was evidenced in 70.8%. It was noted that 27.2% had low, 46.8% moderate, and 26.0% high cardiovascular risk, and that being a woman and of advanced aged negatively influenced the risk. Older adults with metabolic syndrome showed 7.19 times more likelihood to have high cardiovascular risk. Final considerations and implications for the practice The hypertensive elderly patients had high metabolic syndrome prevalence, which significantly increased cardiovascular risk. This result allows for a better planning of nursing care by the nurses in primary health care.


Asunto(s)
Humanos , Masculino , Femenino , Anciano , Atención Primaria de Salud , Síndrome Metabólico/epidemiología , Hipertensión/epidemiología , Brasil/epidemiología , Enfermedad Crónica/epidemiología , Prevalencia , Factores de Riesgo , Enfermeras Practicantes , Obesidad/epidemiología
8.
PLoS One ; 15(12): e0243229, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-33362207

RESUMEN

Causal relations among many statistical variables have been assessed using a Linear non-Gaussian Acyclic Model (LiNGAM). Using access to large amounts of health checkup data from Osaka prefecture obtained during the six fiscal years of years 2012-2017, we applied the DirectLiNGAM algorithm as a trial to extract causal relations among health indices for age groups and genders. Results show that LiNGAM yields interesting and reasonable results, suggesting causal relations and correlation among the statistical indices used for these analyses.


Asunto(s)
Macrodatos , Informática Médica , Adulto , Factores de Edad , Anciano , Anciano de 80 o más Años , Algoritmos , Femenino , Humanos , Japón/epidemiología , Masculino , Síndrome Metabólico/sangre , Síndrome Metabólico/diagnóstico , Síndrome Metabólico/epidemiología , Persona de Mediana Edad , Distribución Normal , Factores Sexuales
9.
PLoS One ; 15(12): e0243576, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-33362213

RESUMEN

BACKGROUND: Cross-sectional studies suggest an association between metabolic syndrome (MetS) and knee osteoarthritis (KOA). We performed a meta-analysis to evaluate whether MetS is an independent risk factor for KOA. METHODS: Prospective cohort studies evaluating the association between MetS and KOA in general population were retrieved from PubMed and Embase. Only studies with multivariate analyses were included. Data were pooled with a random-effect model, which is considered to incorporate heterogeneity among the included studies. RESULTS: Five studies including 94,965 participants were included, with 18,990 people with MetS (20.0%). With a mean follow-up duration of 14.5 years, 2,447 KOA cases occurred. Pooled results showed that MetS was not significant associated with an increased risk of KOA after controlling of factors including body mass index (adjusted risk ratio [RR]: 1.06, 95% CI: 0.92~1.23, p = 0.40; I2 = 33%). Subgroup analysis showed that MetS was independently associated with an increased risk of severe KOA that needed total knee arthroplasty (RR = 1.16, 95% CI: 1.03~1.30, p = 0.02), but not total symptomatic KOA (RR = 0.84, 95% CI: 0.65~1.08, p = 0.18). Stratified analyses suggested that MetS was independently associated with an increased risk of KOA in women (RR = 1.23, 95% CI: 1.03~1.47, p = 0.02), but not in men (RR = 0.90, 95% CI: 0.70~1.14, p = 0.37). CONCLUSIONS: Current evidence from prospective cohort studies did not support MetS was an independent risk factor of overall KOA in general population. However, MetS may be associated with an increased risk of severe KOA in general population, or overall KOA risk in women.


Asunto(s)
Síndrome Metabólico/complicaciones , Osteoartritis de la Rodilla/epidemiología , Osteoartritis de la Rodilla/etiología , Adulto , Anciano , Estudios Transversales , Femenino , Humanos , Incidencia , Masculino , Síndrome Metabólico/epidemiología , Síndrome Metabólico/fisiopatología , Persona de Mediana Edad , Osteoartritis de la Rodilla/cirugía , Estudios Prospectivos , Factores de Riesgo
10.
Artículo en Inglés | MEDLINE | ID: mdl-33353082

RESUMEN

With an increase in the obese population, the prevalence of metabolic syndrome is increasing in Korea. This study aimed to identify sex- and age-specific risk factors for metabolic syndrome. A secondary data analysis was performed using the Korean National Health and Nutritional Examination Survey. Participants comprised 6144 adults aged 20-79 years. The prevalence of metabolic syndrome was high in the middle- and old-aged men (31.9% and 34.5%, respectively) and in old-aged women (39.1%). Risk factors for metabolic syndrome showed different patterns for men and women. In men, alcohol drinking was identified as the main risk factor for hypertension (odds ratio (OR); young = 3.3 vs. middle age = 2.0), high triglycerides (young = 2.4 vs. middle age = 2.2), and high fasting blood sugar (middle age = 1.6). In women, the main risk factors were household income and education level, showing different patterns in different age groups. In conclusion, the vulnerable groups at high risk of metabolic syndrome are those of middle-aged men and women. The pattern of risk factors is sex-specific.


Asunto(s)
Síndrome Metabólico , Adulto , Anciano , Estudios Transversales , Femenino , Humanos , Masculino , Síndrome Metabólico/epidemiología , Persona de Mediana Edad , Encuestas Nutricionales , Prevalencia , República de Corea/epidemiología , Factores de Riesgo , Caracteres Sexuales , Factores Sexuales , Adulto Joven
11.
Rev Assoc Med Bras (1992) ; 66(12): 1628-1632, 2020 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-33331568

RESUMEN

OBJECTIVE: Hot flashes have a negative impact on the quality of life of women during the menopausal transition and thereafter. The progressive reduction in gonadal estrogen levels associated with aging promotes an accumulation of abdominal fat, dyslipidemia, and arterial hypertension, all of which are components of metabolic syndrome (MetS). The objective of the present study was to estimate the prevalence of hot flashes and evaluate their relationship with MetS in women ≥ 40 years of age. METHODS: This was a cross-sectional study involving women aged between 40 and 65 years. We used the Kupperman index to quantify the climacteric symptoms and the National Cholesterol Education Program Adult Treatment Panel III criteria for the diagnosis of MetS. RESULTS: 1,435 women were initially selected, and we obtained information from 647. The mean age at menopause was 45.99 years (SD 6.61 years) and the prevalence of hot flashes and MetS were 55.83% (95% CI: 52.35-59.25%) and 46.29% (95% CI: 44.75-52.53%), respectively. We identified a positive association between MetS and hot flashes (OR 1.16; 95% CI: 1.01-1.33). CONCLUSIONS: In women ≥ 40 years of age, hot flashes are highly prevalent and appear to be associated with MetS.


Asunto(s)
Sofocos , Síndrome Metabólico , Adulto , Anciano , Estudios Transversales , Femenino , Sofocos/epidemiología , Humanos , Menopausia , Síndrome Metabólico/epidemiología , Persona de Mediana Edad , Prevalencia , Calidad de Vida
12.
Artículo en Inglés | MEDLINE | ID: mdl-33322521

RESUMEN

This study investigated the diagnostic accuracy of using an artificial neural network (ANN) for the prediction of metabolic syndrome (MetS) based on socioeconomic status and lifestyle factors. The data of 27,415 subjects who went through examinations and answered questionnaires during three stages from 2006 to 2014 at a health institute in Taiwan were collected and analyzed. The repeated measurements over time were set as predictive factors and used to train and test an ANN for MetS prediction. Among the subjects, 18.3%, 24.6%, and 30.1% were diagnosed with MetS during the respective three stages. ANN analysis applied with an over-sampling technique performed with an area under the curve (AUC) of up to 0.93 based on different models. The over-sampling technique helped improve prediction performance in terms of sensitivity and F2 measures. The results indicated that waist circumference, socioeconomic status (SES), and lifestyle factors can be utilized in a non-invasive screening tool to assist health workers in making primary care decisions when MetS is suspected. By predicting the occurrence of MetS, individuals or healthcare professionals can then develop preventive strategies in time, thus enhancing the effectiveness of health promotion.


Asunto(s)
Tamizaje Masivo/métodos , Síndrome Metabólico , Redes Neurales de la Computación , Adulto , Anciano , Área Bajo la Curva , Femenino , Humanos , Estilo de Vida , Masculino , Síndrome Metabólico/diagnóstico , Síndrome Metabólico/epidemiología , Persona de Mediana Edad , Clase Social , Taiwán/epidemiología , Circunferencia de la Cintura
13.
J Physiol Anthropol ; 39(1): 40, 2020 Dec 14.
Artículo en Inglés | MEDLINE | ID: mdl-33317604

RESUMEN

BACKGROUND: The prevention of metabolic syndrome (MetS) is a major public health concern in Japan. The effects of the relationship between eating behavior and nutritional intake on MetS remained unclear. To evaluate nutrition's role in preventing or exacerbating MetS, we examined the associations among eating behavior, nutritional intake, and MetS for the baseline study in the cohort subjects undergone health checkups. METHODS: Four thousand and four hundred forty-seven Japanese men and women were enrolled at the Saku Central Hospital. They received an anthropometric and clinical examination and were assessed for present illness, lifestyle factors such as physical activity, smoking, drinking, and dietary habits at the enrollment. Eating behavior was analyzed by the Sakata's Eating Behavior Questionnaire. Dietary assessment was made using a brief self-administered diet history questionnaire. Two thousand and six hundred two men and 1844 women aged more than 20 were analyzed. RESULTS: The mean age in men and women were 59.2 and 58.4 years old and the mean body mass index (BMI) were 23.7 and 22.3 kg/m2, respectively. The percentages of MetS were 20.6 in men and 6.1 in women. In some nutrients, significantly higher energy-adjusted intakes in subjects without MetS than with Mets appeared both in men and women after age adjustment. After adjusting by age, energy-adjusted intake beverages in men and cereals in women were significantly higher in subjects with MetS than those without MetS. The scores of all the categories in eating behavior were significantly worse in subjects with MetS than those without MetS. CONCLUSIONS: The differences in dietary intake between subjects with Mets and without Mets were relatively small. The scores of all the categories in eating behavior were worse in subjects with MetS than without MetS. It was suggested that the problem lay in the quality of diet, not in the quantity, caused by bad eating habits. The potential influence of eating behavior and nutritional intake on MetS was presented in men and women.


Asunto(s)
Dieta/estadística & datos numéricos , Ingestión de Energía/fisiología , Conducta Alimentaria/fisiología , Síndrome Metabólico/epidemiología , Anciano , Estudios Transversales , Femenino , Humanos , Japón/epidemiología , Masculino , Persona de Mediana Edad , Valor Nutritivo
14.
Rev. cuba. med ; 59(4): e1561, oct.-dic. 2020. tab
Artículo en Español | LILACS, CUMED | ID: biblio-1144506

RESUMEN

Introducción: El síndrome metabólico es un importante problema de salud y factor de riesgo para un grupo de enfermedades cuyo factor patogénico común es la aterosclerosis. Estas enfermedades constituyen la primera causa de muerte en muchos países y también en Cuba. Objetivo: Caracterizar el perfil del síndrome metabólico en la población de dos consultorios. Método: Se realizó un estudio observacional, descriptivo y transversal en 2 consultorios médicos del policlínico Primero de enero. A los pacientes diagnosticados con síndrome metabólico se les realizó una medición del Índice de Masa Corporal y del colesterol total. Resultados: El síndrome metabólico se diagnosticó en 247 pacientes, su prevalencia en la población estudiada fue de 9,57 por ciento. 121 pacientes (49 por ciento del total) tenían 60 años o más. Los componentes del síndrome metabólico encontrados con mayor frecuencia fueron obesidad abdominal en 168 pacientes (68,01 por ciento de la muestra), hiperglucemia en 115 (46,56 por ciento) e hipertensión arterial en 98 (39,68 por ciento). 86 pacientes (34,82 por ciento) también presentaron hipercolesterolemia. Conclusiones: El síndrome metabólico se presenta frecuentemente en la población mayor de 60 años. La obesidad abdominal, la hiperglicemia y la hipertensión arterial son los componentes del síndrome metabólico hallados con mayor frecuencia. La hipercolesterolemia se detecta a menudo en pacientes con dicho síndrome. Para reducir la morbimortalidad relacionada con el síndrome metabólico es necesario establecer estrategias de detección y control eficaz de los factores de riesgo que lo componen y de la hiperlipidemia frecuentemente asociada(AU)


Introduction: The metabolic syndrome is an important health problem and risk factor for a group of diseases whose common pathogenic factor is atherosclerosis. These diseases are the leading cause of death in many countries, as well in Cuba. Objective: To characterize the profile of the metabolic syndrome in the population of two clinics. Method: An observational, descriptive and cross-sectional study was carried out in 2 medical clinics of Primero de Enero polyclinic. A measurement of the Body Mass Index and total cholesterol was performed in patients diagnosed with metabolic syndrome. Results: The metabolic syndrome was diagnosed in 247 patients; the prevalence in the studied population was 9.57 percent . One hundred twenty one patients (49 percent of the total) were 60 years or older. The most frequently found components of the metabolic syndrome were abdominal obesity in 168 patients (68.01 percent sample), hyperglycemia in 115 (46.56 percent) and arterial hypertension in 98 (39.68 percent). Eighty-six patients (34.82 percent) also had hypercholesterolemia. Conclusions: The metabolic syndrome frequently occurs in the population older than 60 years. Abdominal obesity, hyperglycemia, and high blood pressure are the most frequently found components of the metabolic syndrome. Hypercholesterolemia is often found in patients with this syndrome. In order to reduce the morbidity and mortality related to the metabolic syndrome, it is necessary to establish effective detection and control strategies of the risk factors and of the frequently associated hyperlipidemia(AU)


Asunto(s)
Humanos , Masculino , Femenino , Factores de Riesgo , Síndrome Metabólico/epidemiología , Epidemiología Descriptiva , Estudios Transversales
15.
Medicine (Baltimore) ; 99(50): e23660, 2020 Dec 11.
Artículo en Inglés | MEDLINE | ID: mdl-33327353

RESUMEN

BACKGROUND: Plasminogen activator inhibitor-1 (PAI-1) is considered to be involved in the physiopathological mechanisms of Alzheimer's disease (AD), metabolic syndrome (MetS), and female infertility. Previous studies investigating the association between PAI-14G/5G (rs1799889) gene polymorphism and the risk of AD, MetS, and female infertility have reported inconsistent results. The aim of the present study was to investigate possible associations. METHODS: Eligible studies were retrieved through PubMed, Medline, EMBASE, CNKI, and WANFANG databases. The odds ratios (ORs) and 95% confidence intervals (CIs) were used to assess the associations. Subgroup analyses by ethnicity and mean age, sensitivity analyses, and publication bias were performed. RESULTS: Five studies (four articles) for AD, six studies (six articles) for MetS, and four studies (four articles) for female infertility were included in this meta-analysis. Our results showed no significant associations between the PAI-14G/5G polymorphism and the risk of AD and female infertility in five genetic models. For the risk of MetS, the PAI-1 4G/5G (rs1799889) polymorphism may be associated with the risk of MetS (4G vs 5G, OR = 1.31, 95%CI = 1.04-1.64, P = .021), especially in Asians (4G/4G vs 4G/5G+5G/5G, OR = 1.38, 95%CI = 1.01-1.87, P = .041) and patients with mean age > 50 years old (4G/4G vs 4G/5G+5G/5G, OR = 1.36, 95%CI = 1.03-1.78, P = .029). CONCLUSION: The present meta-analysis suggested that the PAI-1 4G/5G polymorphism might be associated with the risk of MetS, but no evidence was detected for AD and female infertility.


Asunto(s)
Enfermedad de Alzheimer/genética , Infertilidad Femenina/genética , Síndrome Metabólico/genética , Inhibidor 1 de Activador Plasminogénico/genética , Enfermedad de Alzheimer/epidemiología , Estudios de Casos y Controles , Femenino , Predisposición Genética a la Enfermedad , Humanos , Infertilidad Femenina/epidemiología , Síndrome Metabólico/epidemiología , Oportunidad Relativa , Polimorfismo de Nucleótido Simple , Factores de Riesgo
16.
BMJ Open Respir Res ; 7(1)2020 12.
Artículo en Inglés | MEDLINE | ID: mdl-33328246

RESUMEN

BACKGROUND: Several characteristics of the metabolic syndrome, such as obesity and hypertension, have emerged as risk factors for a poor clinical outcome in COVID-19. However, most reports lack data on the metabolic syndrome itself. This study investigated prospectively the relationship between respiratory deterioration and the presence of metabolic syndrome or abdominal adiposity in patients with COVID-19. METHODS: A prospective observational cohort study analysing patients with respiratory symptoms who presented at a local emergency department in the Netherlands. The influence of abdominal adiposity-assessed by an increased waist-hip ratio-and metabolic syndrome on respiratory deterioration and the length of hospital stay were analysed with multivariable logistic regressions and Kaplan-Meier analyses. RESULTS: In total, 166 patients were analysed, of whom 86 (52%) tested positive for COVID-19. The prevalence of metabolic syndrome did not differ between patients with COVID-19 with and without the need for intubation or level of supportive care (37.5% vs 48.4%, p=0.338). In contrast, abdominal adiposity is an independent risk factor for respiratory distress in COVID-19, adjusted for metabolic syndrome, age, gender and BMI (OR 1.11, 95% CI 1.02 to 1.20, p=0.014). CONCLUSION: This study shows that abdominal adiposity, and not the presence of metabolic syndrome, is associated with clinical deterioration in COVID-19. This prospective study provides further insight into the risk stratification of patients with COVID-19 based on a simple measurement as the waist and hip circumference. TRIAL REGISTRATION NUMBER: NL8580.


Asunto(s)
/complicaciones , Síndrome Metabólico/complicaciones , Obesidad Abdominal/complicaciones , /etiología , Adiposidad , Adulto , Anciano , /epidemiología , Femenino , Humanos , Hipertensión/complicaciones , Tiempo de Internación/estadística & datos numéricos , Masculino , Síndrome Metabólico/diagnóstico , Síndrome Metabólico/epidemiología , Persona de Mediana Edad , Países Bajos/epidemiología , Obesidad/complicaciones , Obesidad Abdominal/epidemiología , Prevalencia , Estudios Prospectivos , /mortalidad , Factores de Riesgo , Relación Cintura-Cadera/métodos
17.
Front Cell Infect Microbiol ; 10: 575559, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-33363049

RESUMEN

The current COVID-19 pandemic is a great challenge for worldwide researchers in the human microbiota area because the mechanisms and long-term effects of the infection at the GI level are not yet deeply understood. In the current review, scientific literature including original research articles, clinical studies, epidemiological reports, and review-type articles concerning human intestinal infection with SARS-CoV-2 and the possible consequences on the microbiota were reviewed. Moreover, the following aspects pertaining to COVID-19 have also been discussed: transmission, resistance in the human body, the impact of nutritional status in relation to the intestinal microbiota, and the impact of comorbid metabolic disorders such as inflammatory bowel disease (IBS), obesity, and type two diabetes (T2D). The articles investigated show that health, age, and nutritional status are associated with specific communities of bacterial species in the gut, which could influence the clinical course of COVID-19 infection. Fecal microbiota alterations were associated with fecal concentrations of SARS-CoV-2 and COVID-19 severity. Patients suffering from metabolic and gastrointestinal (GI) disorders are thought to be at a moderate-to-high risk of infection with SARS-CoV-2, indicating the direct implication of gut dysbiosis in COVID-19 severity. However, additional efforts are required to identify the initial GI symptoms of COVID-19 for possible early intervention.


Asunto(s)
/microbiología , Disbiosis/etiología , Microbioma Gastrointestinal , Pandemias , /fisiología , Animales , /epidemiología , Comorbilidad , Diabetes Mellitus Tipo 2/epidemiología , Diabetes Mellitus Tipo 2/microbiología , Reservorios de Enfermedades/virología , Enterocitos/patología , Enterocitos/virología , Heces/microbiología , Heces/virología , Enfermedades Gastrointestinales/etiología , Enfermedades Gastrointestinales/microbiología , Humanos , Síndrome del Colon Irritable/epidemiología , Síndrome del Colon Irritable/microbiología , Síndrome Metabólico/epidemiología , Síndrome Metabólico/microbiología , Obesidad/epidemiología , Obesidad/microbiología , Factores de Riesgo , /patogenicidad
18.
Artículo en Inglés | MEDLINE | ID: mdl-33374826

RESUMEN

(1) Background: The health implications associated with the metabolically healthy obese (MHO) phenotype, in particular related to symptoms of depression, are still not clear. the purpose of this study is to check whether depression and metabolic status are relevant by classifying them into four groups in accordance with the MHO diagnostic standard. Other impressions seen were the differences between sexes and the effects of the MHO on the occurrence of depression. (2) Methods: A sample of 3,586,492 adult individuals from the National Health Insurance Database of Korea was classified into four categories by their metabolic status and body mass index: (1) metabolically healthy non-obese (MHN); (2) metabolically healthy obese (MHO); (3) metabolically unhealthy non-obese (MUN); and (4) metabolically unhealthy obese (MUO). Participants were followed for six to eight years for new incidences of depression. The statistical significance of the general characteristics of the four groups, as well as the mean differences in metabolic syndrome risk factors, was assessed with the use of a one-way analysis of variance (ANOVA). (3) Results: The MHN ratio in women was higher than in men (men 39.3%, women 55.2%). In both men and women, depression incidence was the highest among MUO participants (odds ratio (OR) = 1.01 in men; OR = 1.09 in women). It was concluded as well that, among the risk factors of metabolic syndrome, waist circumference was the most related to depression. Among the four groups, the MUO phenotype was the most related to depression. Furthermore, in women participants, MHO is also related to a higher risk of depressive symptoms. These findings indicate that MHO is not a totally benign condition in relation to depression in women. (4) Conclusion: Therefore, reducing metabolic syndrome and obesity patients in Korea will likely reduce the incidence of depression.


Asunto(s)
Depresión/epidemiología , Obesidad Metabólica Benigna/psicología , Adulto , Índice de Masa Corporal , Femenino , Humanos , Masculino , Síndrome Metabólico/epidemiología , Persona de Mediana Edad , Programas Nacionales de Salud , Obesidad Metabólica Benigna/epidemiología , República de Corea/epidemiología , Factores de Riesgo , Circunferencia de la Cintura
20.
Zhonghua Liu Xing Bing Xue Za Zhi ; 41(9): 1514-1517, 2020 Sep 10.
Artículo en Chino | MEDLINE | ID: mdl-33076609

RESUMEN

Objective: To investigate the blood pressure control and its influencing factors in hypertension patients with MS. Methods: Between January 2017 and December 2018, more than 78 000 residents aged 35-75 years selected through convenient sampling were invited to participant in China Patient-Centered Evaluative Assessment of Cardiac Event Million Persons Project in Fujian province, physical and laboratory tests were conducted for them, and their basic information were recorded. A total of 5 281 hypertension patients with MS were included in the study. Results: The treatment rate of hypertension patients with MS was 55.5%, and the control rate was 7.2%. The control rate was higher in patients who were older, women, had advanced education level, had history or family history of cardiovascular disease. The results of multivariate analysis indicated that living area (urban or rural), cardiovascular history, diabetes, urine protein, BMI had impacts on both treatment and control of hypertension. Family history of cardiovascular disease, age, self-management of hypertension, dyslipidemia, waist circumference and drinking had impacts on the treatments, and gender had effects on the control. Conclusions: The treatment rate of hypertension patients with MS was unsatisfactory and the control rate was low. Intervention should be strengthened in rural area, males and young age groups, and activity of self-management group of hypertension should be conducted regularly.


Asunto(s)
Hipertensión , Síndrome Metabólico , Adulto , Anciano , China/epidemiología , Femenino , Humanos , Hipertensión/epidemiología , Hipertensión/prevención & control , Masculino , Síndrome Metabólico/epidemiología , Persona de Mediana Edad , Factores Socioeconómicos , Resultado del Tratamiento
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