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1.
Rev Med Suisse ; 17(732): 610-614, 2021 Mar 31.
Artículo en Francés | MEDLINE | ID: mdl-33793097

RESUMEN

Wells' syndrome is a rare inflammatory eosinophilic dermatosis. It typically appears as a sudden-onset of one or multiple inflammatory plaques associated with a pruritus. General symptoms are rare. There is often blood eosinophilia and a marked dermal eosinophilic infiltrate with flame figures on skin biopsy. Numerous trigger factors and associated diseases are described. The etiology is unclear. Most experts believe it to be a type IV hypersensitivity reaction in predisposed individuals with an imbalance TH1/TH2 cells. Circulating TH2 cells may be implicated by producing IL- 5 which stimulates eosinophils' degranulation. The aim of this article is to review the diagnostic and therapeutic options of this pathology knowing that the main differential diagnosis is cellulitis of infectious origin.


Asunto(s)
Celulitis (Flemón) , Eosinofilia , Celulitis (Flemón)/diagnóstico , Celulitis (Flemón)/etiología , Eosinofilia/diagnóstico , Eosinofilia/etiología , Humanos , Piel , Síndrome
2.
Artículo en Chino | MEDLINE | ID: mdl-33794621

RESUMEN

Hereditary deafness is divided into syndromic hearing loss and non-syndromic hearing loss according to whether it is accompanied by other system dysfunction. The early identification and diagnosis of syndromic hearing loss is very important, including clinical and molecular diagnosis. Early diagnosis can predict the progress of hearing loss, other systemic disorders and guide treatment. Thus otolaryngologists are likely to become the first doctors to treat children with syndromic hearing loss, it is more necessary to master the clinical and molecular diagnosis methods of common syndromic hearing loss, and cooperate with doctors of other relevant departments for early intervention and treatment. Therefore, this article reviewed the common features, molecular diagnostic methods and treatment strategies for syndromic hearing loss.


Asunto(s)
Sordera , Pérdida Auditiva Sensorineural , Pérdida Auditiva , Niño , Pérdida Auditiva/diagnóstico , Pérdida Auditiva/terapia , Humanos , Mutación , Síndrome
3.
Environ Health Prev Med ; 26(1): 36, 2021 Mar 22.
Artículo en Inglés | MEDLINE | ID: mdl-33752592

RESUMEN

BACKGROUND: Among former Olympic-level athletes, engagement in different sport disciplines has been associated with mortality risk in subsequent years. However, limited evidence is available on whether engagement in different sport disciplines at a young age is associated with locomotive syndrome (LS) risk later in life. This study examined the relationship between engagement in different sport disciplines during university years and LS risk in older age among former university athletes. METHODS: Participants were 274 middle-aged and 294 older men alumni who graduated from a school of physical education in Japan. LS risk was defined as answering "yes" to any of the Loco-check questions. Data on university sports club membership were collected using questionnaires. University clubs were classified into three groups of cardiovascular intensity (low, moderate, high), following the classification system of sport disciplines by the American College of Cardiology. This classification considers the static and dynamic components of an activity, which correspond to the estimated percent of maximal voluntary contraction reached and maximal oxygen uptake achieved, respectively. University clubs were grouped based on the risk of bodily collision (no, yes) and extent of physical contact (low, moderate, high). Relationships between engagement in different sport disciplines and LS risk were analyzed using Cox proportional hazards models, and adjusted for age, height, weight, joint disease, habitual exercise, and smoking and drinking status. RESULTS: Adjusted hazard ratios and 95% confidence intervals associated with the low, moderate, and high cardiovascular intensity sports were 1.00 (reference), 0.48 (0.22-1.06, P = 0.070), and 0.44 (0.20-0.97, P = 0.042) in older men, respectively; however, there was no significant association between these parameters among middle-aged men. Engagement in sports associated with physical contact and collision did not affect LS risk in either group. CONCLUSIONS: Engagement in sports associated with high cardiovascular intensity during university years may reduce the risk of LS in later life. Encouraging young people to participate in such activities might help reduce LS prevalence among older populations.


Asunto(s)
Atletas/estadística & datos numéricos , Locomoción , Limitación de la Movilidad , Trastornos Motores/epidemiología , Equilibrio Postural , Adulto , Anciano , Anciano de 80 o más Años , Ejercicio Físico , Evaluación Geriátrica , Humanos , Japón/epidemiología , Masculino , Persona de Mediana Edad , Trastornos Motores/etiología , Prevalencia , Modelos de Riesgos Proporcionales , Factores de Riesgo , Deportes/fisiología , Deportes/estadística & datos numéricos , Síndrome , Adulto Joven
5.
Vnitr Lek ; 67(1): 58-61, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33752393

RESUMEN

Incidence of ANCA antibodies in patients with systemic lupus erythematosus (SLE) is described in 24-31 %, but they are not related to the distribution and severity of organ involvement in SLE; the routine monitoring is not recommended. Overlap syndrome of systemic lupus erythematosus and ANCA associated vasculitis (AAV) is rare. The difficult diagnosis and treatment of this syndrome is described in this case report of the patient with SLE and severe kidney involvement resulting from AAV.


Asunto(s)
Vasculitis Asociada a Anticuerpos Citoplasmáticos Antineutrófilos , Lupus Eritematoso Sistémico , Vasculitis Asociada a Anticuerpos Citoplasmáticos Antineutrófilos/complicaciones , Humanos , Incidencia , Lupus Eritematoso Sistémico/complicaciones , Síndrome
6.
Vestn Otorinolaringol ; 86(1): 6-10, 2021.
Artículo en Ruso | MEDLINE | ID: mdl-33720643

RESUMEN

Despite the rare incidence of Van der Hoeve syndrome in the population, the problem of treating patients with this type of disease is important for modern science and practical medicine. One of the most difficult tasks in treatment is to improve the quality of hearing. The world scientific community lacks a unified coordinated approach to the methods of auditory rehabilitation of patients with Van der Hoeve syndrome. In recent years, there have been tendencies in the scientific literature to increase the frequency of non-surgical approach due to the low incidence of satisfactory results of surgical treatment. In this regard, we present our experience of complex treatment of patients with Van der Hove syndrome, based on the use of modern surgical technologies and conservative pathogenetically substantiated treatment.


Asunto(s)
Sordera , Osteogénesis Imperfecta , Audición , Pruebas Auditivas , Humanos , Síndrome
7.
J Spec Oper Med ; 21(1): 55-64, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33721308

RESUMEN

BACKGROUND: EMS personnel are often exposed to traumatic material during their duties. It is unknown how prior military experience affects the presence of stress in EMS personnel. METHODS: This was a prospective cross-sectional study. Nine EMS agencies provided data on call mix, while individuals were recruited during training evolutions. The survey evaluated sociodemographic factors and the relationship between childhood trauma and previous military service using the Adverse Childhood Experiences questionnaire, Life Events Checklist DSM-5, and Military History Questionnaire. Descriptive statistics calculated personal trauma profiles, comparing civilian EMS personnel to those with prior service. Hierarchical linear regression assessed the predictive utility of military history to scores on the Impact of Events Scale-Revised. RESULTS: A total of 765 EMS personnel participated in the study; 52.8% were male, 11.4% were minorities, and 11.6% had prior military service. A total of 64.4% of civilian EMS providers had any stress syndrome, while that number was 71.8% in those with prior military service. Hierarchical linear regression identified that years of service and the performance of combat patrols or other dangerous duty accounted for a unique criterion variance in the regression model. CONCLUSIONS: Prior military service or combat deployments alone do not contribute to the presence of stress syndromes. However, performance of combat patrols or other dangerous duties while deployed was a contributing factor. These results must be interpreted holistically, as other factors contribute to the presence of vicarious trauma (VT) in EMS personnel who are also veterans.


Asunto(s)
Desgaste por Empatía , Servicios Médicos de Urgencia , Personal Militar , Trastornos por Estrés Postraumático , Niño , Estudios Transversales , Femenino , Humanos , Masculino , Estudios Prospectivos , Trastornos por Estrés Postraumático/diagnóstico , Trastornos por Estrés Postraumático/epidemiología , Síndrome
8.
Neurology ; 96(9): 460-461, 2021 03 02.
Artículo en Inglés | MEDLINE | ID: mdl-33649086
9.
Brain Nerve ; 73(3): 257-263, 2021 Mar.
Artículo en Japonés | MEDLINE | ID: mdl-33678617

RESUMEN

Foreign accent syndrome (FAS) is a rare speech disorder characterized by the emergence of a foreign accent. To date, more than a hundred cases of FAS have been reported, and the impression of accent change is regarded to be the result of a combination of segmental deficits (i.e., phonetic distortions and phonemic paraphasias) and supra-segmental changes (i.e., stress, pitch, or rhythm variation). The most common etiology of FAS is stroke, followed by other causes. Various lesion locations have been identified to cause FAS. Owing to various heterogeneous etiologies and lesion locations, it remains controversial whether there is enough consistency or universality to treat FAS as a "syndrome".


Asunto(s)
Afasia , Accidente Cerebrovascular , Humanos , Fonética , Trastornos del Habla , Síndrome
11.
Zhongguo Zhong Yao Za Zhi ; 46(4): 782-785, 2021 Feb.
Artículo en Chino | MEDLINE | ID: mdl-33645078

RESUMEN

Based on the characteristics of clinical symptoms of chronic skin ulcers in traditional Chinese and Western medicine, the current animal models of skin ulcers are summarized. This article analyzes the advantages and disadvantages of animal models according to the etiology and pathogenesis of chronic skin ulcers, traditional Chinese and Western medicine diagnostic criteria and observation indicators, and eva-luates the agreement between the existing animal models and the characteristics of clinical syndromes of traditional Chinese and Western medicine for chronic skin ulcers. Through analysis and comparison, it is found that most of the existing modeling methods are single-factor animal models, and there are certain gaps in the physiological and pathological characteristics of chronic skin ulcers caused by clinical multi-factors and interactions. Most of the modeling methods are guided by Western medicine. The lack of pathogenic factors of traditional Chinese medicine(TCM) in the process of modeling. Therefore, this article proposes to establish a reasonable quantification standard for chronic skin ulcer animal models, and to establish a combination model of chronic skin ulcer disease with traditional Chinese and Western medicine as the focus of future animal model research.


Asunto(s)
Medicamentos Herbarios Chinos , Medicina , Úlcera Cutánea , Animales , China , Medicina China Tradicional , Úlcera Cutánea/tratamiento farmacológico , Síndrome
12.
Zhongguo Zhong Yao Za Zhi ; 46(2): 494-503, 2021 Jan.
Artículo en Chino | MEDLINE | ID: mdl-33645139

RESUMEN

Coronavirus disease 2019(COVID-19) refers to the pneumonia caused by novel coronavirus(2019-nCoV) infection in 2019. It is highly infectious, with quick spreading and a wide range of impact. It has been broken out in many countries around the world and has become a public health emergency of international concern. Chinese medicine has a long history in treating plague, and viral disease is the clinical advantage in Chinese medicine. Under the premise that there is currently no specific drug treatment, Chinese medicine has achieved certain effects in the treatment of COVID-19, which has attracted much attention and has been upgraded to a national strategy. Regarding the treatment of COVID-19 with Chinese medicine, it is believed that in terms of the name of Chinese medicine, the modern connotation of "uniform of typhoid and febrile disease" should be re-recognized, and it is advisable to use drugs based on specific clinical prescriptions and indications. In terms of pathogenesis, the COVID-19 has the pathogenesis rules including from the mild to severe conditions, from the surface to the inside, from the excess syndrome to the deficiency syndrome. We should pay attention to the Taiyang syndrome damaged by wet disease in initial stage, Shaoyang syndrome complicated with Yangming syndrome in the middle stage, phlegm-heat obstructing lung in critical period, lung and spleen deficiency in the recovery stage. In terms of clinical treatment strategies, Dayuan Yin is recommended to induce sweat and disperse the stasis in early stage. Xiaochaihu Decoction and Maxing Shigan Decoction is used to relieve both exterior and interior symptoms in middle stage. In critical stage, Tingli Dazao Xiefei Decoction, Weijing Decoction, Xuanbai Chengqi Decoction, Xiaoxianxiong Decoction, and Sanzi Yangqin Decoction are considered to reduce phlegm and clear heat. We should pay attention to nourishing Qi and strengthening the spleen by Zhuye Shigao Decoction, Sha-shen Maidong Decoction, and Liujunzi Decoction in the later recovery period. It shall be noted that, no matter in the initial mild stage, the middle and critical stages, or in the later recovery stage, Chinese medicine plays an important role, including preventing mild to severe disease, shortening the fever time, improving cough symptoms, increasing blood oxygen saturation and reducing mortality. Many studies have shown that the classical herbal formulae can alleviate the cytokine storm, regulate the immune imbalance, and produce the potential effect of synergistic treatment for COVID-19 through multiple components, multiple targets, and multiple pathways.


Asunto(s)
Medicamentos Herbarios Chinos , Medicamentos Herbarios Chinos/uso terapéutico , Humanos , Medicina China Tradicional , Síndrome
13.
Medicine (Baltimore) ; 100(9): e24698, 2021 Mar 05.
Artículo en Inglés | MEDLINE | ID: mdl-33655934

RESUMEN

RATIONALE: Capsular warning syndrome (CWS) is a term to describe stereotyped lacunar transient ischemic attacks (TIAs). Patients with CWS are at high risk of developing completed stroke. However, the exact pathophysiology of CWS is still unclear, and there is no conclusive clinical strategy for CWS patients. PATIENT SYMPTOMS: Two cases of middle-aged men with hypertension, hyperlipidemia, and diabetes mellitus presented with fluctuating right-sided weakness, numbness, and dysarthria. DIAGNOSES: These two patients were diagnosed with CWS. INTERVENTIONS: Recombinant tissue plasminogen activator (rt-PA) intravenous thrombolysis (0.9 mg/kg) was administered first and treated with aspirin (100 mg) and clopidogrel (75 mg) after 24 h of rt-PA for 21 days following by aspirin (100 mg) alone. OUTCOMES: Both cases got favorable clinical outcomes of somatic symptoms. In addition, diffusion-weighted imaging (DWI or DW-MRI) showed that ischemic injury disappeared in case 1 while maintained within a reasonable range in case 2. LESSONS: Early recognition and rt-PA/dual antiplatelet treatment may be an effective strategy for patients with CWS.


Asunto(s)
Aspirina/uso terapéutico , Clopidogrel/uso terapéutico , Fibrinolíticos/uso terapéutico , Ataque Isquémico Transitorio/tratamiento farmacológico , Activador de Tejido Plasminógeno/uso terapéutico , Imagen de Difusión por Resonancia Magnética , Terapia Antiplaquetaria Doble , Humanos , Masculino , Persona de Mediana Edad , Proteínas Recombinantes/uso terapéutico , Accidente Cerebrovascular/prevención & control , Síndrome , Terapia Trombolítica , Resultado del Tratamiento
14.
Rev Soc Bras Med Trop ; 54: e0865, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33759933

RESUMEN

This report describes a case of multisystem inflammatory syndrome in a child that evolved with a pattern of toxic shock syndrome with coronary artery ectasia and neurological involvement, documented by magnetic resonance imaging, with changes in the corpus callosum and myopathy in the pelvic girdle and paravertebral musculature.


Asunto(s)
Enfermedades Musculares , Niño , Humanos , Imagen por Resonancia Magnética , Enfermedades Musculares/diagnóstico , Síndrome , Síndrome de Respuesta Inflamatoria Sistémica
15.
Medicine (Baltimore) ; 100(12): e25041, 2021 Mar 26.
Artículo en Inglés | MEDLINE | ID: mdl-33761663

RESUMEN

BACKGROUND: Post-stroke depression (PSD) is one of the most common stroke complications with high morbidity. Researchers have done much clinical research on Traditional Chinese Medicine (TCM) treatment, but very little research on diagnosis. Based on the thought of combination of disease and syndrome, this study will establish a unified and objective quantitative diagnosis model of TCM syndromes of PSD, so as to improve the clinical diagnosis and treatment of PSD. OBJECTIVE: First: To establish a unified and objective quantitative diagnosis model of TCM syndromes in PSD under different disease courses, and identify the corresponding main, secondary, and concurrent symptoms, which are based on the weighting factor of each TCM symptom. Second: To find out the relationship between different stages of PSD and TCM syndromes. Clarify the main syndrome types of PSD under different stages of disease. Reveal the evolution and progression mechanism of TCM syndromes of PSD. METHODS AND ANALYSIS: This is a retrospective study of PSD TCM diagnosis. Three hundred patients who were hospitalized in the First Teaching Hospital of Tianjin University of TCM with complete cases from January 2014 to January 2019 are planned to be recruited. The study will mainly collect the diagnostic information from the cases, find the related indicators of TCM and Western medicine in PSD, and clarify the relationship between different disease stages and TCM syndromes. Finally, the PSD TCM syndrome quantitative diagnosis model will be established based on the operation principle of Back Propagation (BP) artificial neural network. CONCLUSION: To collect sufficient medical records and establish models to speed up the process of TCM diagnosis.


Asunto(s)
Depresión/diagnóstico , Medicina China Tradicional , Accidente Cerebrovascular/psicología , Adolescente , Adulto , Anciano , Depresión/terapia , Humanos , Persona de Mediana Edad , Estudios Retrospectivos , Síndrome , Adulto Joven
16.
Medicine (Baltimore) ; 100(8): e24939, 2021 Feb 26.
Artículo en Inglés | MEDLINE | ID: mdl-33663133

RESUMEN

BACKGROUND: Manual therapy is a common technique for the treatment of (CCS) cervicogenic cephalic syndrome, but the efficiency is various. The aim of the study is to evaluate the evidence pertaining to the efficiency and safety of using manual therapy to treat patients with CCS. METHODS: We searched the electronic databases including PubMed, ScienceDirect, and the Cochrane Library. Only randomized controlled trials (RCTs) were enrolled in this systematic review and cumulative meta-analysis. RESULTS: A total of 8 RCTs with 395 patients were included for meta-analysis. Patients who underwent manual therapy showed lower scores of visual analog scale (VAS) (weighted mean difference) WMD = 1.7, 95% confidence interval CI = 0.74-2.65, P = .0005); dizziness handicap inventory (DHI) (WMD = 0.66, 95%CI = 0.31-1, P = .0002); and neck disability index (NDI) (WMD = 0.59, 95%CI = 0.23-0.96, P = .002) and better rotation range of motion (ROM) of the cervical spine (WMD = -6.54, 95%CI = -7.60 to -5.48, P < .0001). However, these patients did not show much benefit from manual therapy with respect to the frequency of CCS episodes and head repositioning accuracy (HRA). No serious adverse effects were reported in our included studies lasting longer than 24 hours. CONCLUSIONS: Manual therapy offers an effective and safe approach to treat CCS with lower VAS, DHI, and NDI scores and better cervical spinal movement. Further high-quality RCTs are required to provide more conclusive evidence. SYSTEMATIC REVIEW REGISTRATION NUMBER: PROSPERO172740.


Asunto(s)
Dolor Crónico/terapia , Mareo/terapia , Manipulación Espinal/métodos , Dolor de Cuello/terapia , Femenino , Humanos , Masculino , Ensayos Clínicos Controlados Aleatorios como Asunto , Rango del Movimiento Articular , Síndrome
18.
Ther Umsch ; 78(1): 2-10, 2021 Feb.
Artículo en Alemán | MEDLINE | ID: mdl-33538635

RESUMEN

Strategy for Chronic Coronary Syndrome - PCI or optimal medical therapy Abstract. In the new guidelines of the European Society of Cardiology (ESC), the previous term "stable coronary artery disease (CAD)" was replaced by a new term "chronic coronary syndrome (CCS)" in order to highlight the chronic but also progressive pathological character of CAD. Both optimal medical therapy and myocardial revascularization play a central role in the treatment of patients with CCS. However, due to the heterogeneity of CCS, it is a challenge to determine in clinical practice which patients may benefit from percutaneous coronary intervention (PCI). In addition, the importance of PCI is still controversial, especially in patients with CCS. Hence, this review discusses diagnostic and therapeutic approaches in patients with CCS considering the current ESC-guidelines and the ISCHEMIA Trial (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches) in order to outline the optimal strategy for improving symptoms and prognosis.


Asunto(s)
Enfermedad de la Arteria Coronaria , Intervención Coronaria Percutánea , Humanos , Revascularización Miocárdica , Síndrome , Resultado del Tratamiento
19.
Rev Med Liege ; 76(2): 77-82, 2021 Feb.
Artículo en Francés | MEDLINE | ID: mdl-33543851

RESUMEN

Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated food allergy. Its pathophysiology is still poorly understood. FPIES mainly affects infant and young children, although cases have been reported in adults. Its symptomatology is restricted to gastrointestinal manifestations and the onset of allergic reaction subsequent to exposure is delayed. The most common culprit for children is cow's milk. Initial clinical presentation of FPIES is oftentimes acute, though it can also be chronic. Diagnosis relies on clinical criteria, which have been recently redefined and subject to international consensus. Through two clinical cases, this report aims to describe the characteristics of this emerging disease as well as delineate the treatment thereof.


Asunto(s)
Enterocolitis , Hipersensibilidad a los Alimentos , Adulto , Alérgenos , Animales , Bovinos , Niño , Preescolar , Proteínas en la Dieta , Enterocolitis/diagnóstico , Enterocolitis/etiología , Femenino , Hipersensibilidad a los Alimentos/diagnóstico , Hipersensibilidad a los Alimentos/etiología , Humanos , Lactante , Síndrome
20.
Soins Gerontol ; 26(147): 34-36, 2021.
Artículo en Francés | MEDLINE | ID: mdl-33549239

RESUMEN

The psychomotor disadaptation syndrome (PDS) was first described 34 years ago by the geriatric research team from Dijon, France. This syndrome was initially called "psychomotor regression syndrome". It was renamed PDS in the 1990s following considerable advances in the understanding of its pathophysiology and management. Since the 2000s, a condition known as sub-cortical-frontal dysfunction (syndrome sous-cortico-frontal) has become synonymous with PDS. Effective management of PDS requires a multidisciplinary approach that includes physicians, physiotherapists, psychologists and the entire geriatrics healthcare team.


Asunto(s)
Equilibrio Postural , Postura , Trastornos Psicomotores , Anciano , Francia , Humanos , Síndrome
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