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2.
BMC Oral Health ; 21(1): 135, 2021 03 19.
Artículo en Inglés | MEDLINE | ID: mdl-33740959

RESUMEN

BACKGROUND: Platelet-rich fibrin (PRF) has been widely utilized in modern medicine and dentistry owing to its ability to rapidly stimulate neoangiogenesis, leading to faster tissue regeneration. While improvements over traditional platelet rich plasma therapies (which use chemical additives such as bovine thrombin and calcium chloride) have been observed, most clinicians are unaware that many tubes utilized for the production of 'natural' and '100% autologous' PRF may in fact contain chemical additives without appropriate or transparent knowledge provided to the treating clinician. The aim of this overview article is therefore to provide a technical note on recent discoveries related to PRF tubes and describe recent trends related to research on the topic from the authors laboratories. METHODS: Recommendations are provided to clinicians with the aim of further optimizing PRF clots/membranes by appropriate understanding of PRF tubes. The most common additives to PRF tubes reported in the literature are silica and/or silicone. A variety of studies have been performed on their topic described in this narrative review article. RESULTS: Typically, PRF production is best achieved with plain, chemical-free glass tubes. Unfortunately, a variety of other centrifugation tubes commonly used for lab testing/diagnostics and not necessarily manufactured for human use have been utilized in clinical practice for the production of PRF with unpredictable clinical outcomes. Many clinicians have noted an increased variability in PRF clot sizes, a decreased rate of clot formation (PRF remains liquid even after an adequate protocol is followed), or even an increased rate in the clinical signs of inflammation following the use of PRF. CONCLUSION: This technical note addresses these issues in detail and provides scientific background of recent research articles on the topic. Furthermore, the need to adequately select appropriate centrifugation tubes for the production of PRF is highlighted with quantitative data provided from in vitro and animal investigations emphasizing the negative impact of the addition of silica/silicone on clot formation, cell behavior and in vivo inflammation.


Asunto(s)
Fibrina Rica en Plaquetas , Plasma Rico en Plaquetas , Animales , Bovinos , Centrifugación , Humanos , Dióxido de Silicio , Siliconas
3.
Medicine (Baltimore) ; 100(13): e25285, 2021 Apr 02.
Artículo en Inglés | MEDLINE | ID: mdl-33787613

RESUMEN

ABSTRACT: Surface treatment of medical devices may be a way of avoiding the need for replacement of these devices and the comorbidities associated with infection. The aim of this study was to evaluate whether pre- and postcontamination washing of 2 prostheses with different textures can decrease bacterial contamination.The following microorganisms were evaluated: Staphylococcus aureus, Staphylococcus epidermidis, Proteus mirabilis and Enterococcus faecalis. Silicone and expanded polytetrafluoroethylene vascular prostheses were used and divided into 3 groups: prostheses contaminated; prostheses contaminated and treated before contamination; and prostheses contaminated and treated after contamination. Treatments were performed with antibiotic solution, chlorhexidine and lidocaine. After one week of incubation, the prostheses were sown in culture medium, which was incubated for 48 hours. The area of colony formation was evaluated by fractal dimension, an image analysis tool.The antibiotic solution inhibited the growth of S epidermidis and chlorhexidine decrease in 53% the colonization density for S aureus in for both prostheses in the pre-washing. In postcontamination washing, the antibiotic solution inhibited the growth of all bacteria evaluated; there was a 60% decrease in the colonization density of S aureus and absence of colonization for E faecalis with chlorhexidine; and lidocaine inhibited the growth of S aureus in both prostheses.Antibiotic solution showed the highest efficiency in inhibiting bacterial growth, especially for S epidermidis, in both washings. Lidocaine was able to reduce colonization by S aureus in post-contamination washing, showing that it can be used as an alternative adjuvant treatment in these cases.


Asunto(s)
Prótesis Vascular/microbiología , Descontaminación/métodos , Desinfectantes/administración & dosificación , Infecciones Relacionadas con Prótesis/prevención & control , Antibacterianos/administración & dosificación , Recuento de Colonia Microbiana , Enterococcus faecalis/crecimiento & desarrollo , Humanos , Lidocaína/administración & dosificación , Politetrafluoroetileno , Diseño de Prótesis , Infecciones Relacionadas con Prótesis/microbiología , Proteus mirabilis/crecimiento & desarrollo , Siliconas , Staphylococcus aureus/crecimiento & desarrollo , Staphylococcus epidermidis/crecimiento & desarrollo
4.
Methods Mol Biol ; 2269: 269-282, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33687686

RESUMEN

Conventional two-dimensional as well as established three-dimensional cell culture systems exhibit a high modulus of elasticity, which largely do not represent the stiffness of human organs. This chapter describes a protocol to establish 3D cell cultures of human adipose tissue-derived mesenchymal stromal cells (hAT-MSC) on low stiffness silicon scaffolds. These feature a defined growing environment with a stiffness close to physiology, thus being useful for in vitro investigations for multiple applications.


Asunto(s)
Tejido Adiposo/metabolismo , Diferenciación Celular , Células Madre Mesenquimatosas/metabolismo , Osteogénesis , Siliconas/química , Andamios del Tejido/química , Tejido Adiposo/citología , Técnicas de Cultivo de Célula , Humanos , Células Madre Mesenquimatosas/citología
5.
Sensors (Basel) ; 21(4)2021 Feb 05.
Artículo en Inglés | MEDLINE | ID: mdl-33562707

RESUMEN

Porous polymer dielectric materials have been developed to increase the sensitivity of capacitive pressure sensors, so that they might expand capacitive sensor use, and promote the realization of the advantages of this class of sensor in further fields. However, their use has not been demonstrated in physiological monitoring applications such as respiration monitoring and body position detection during sleep; an area in need of unmet medical attention for conditions such as sleep apnea. Here, we develop and characterize a sensor comprised of a poly dimethylsiloxane (PDMS) sponge dielectric layer, and PDMS/carbon black (CB) blend electrode layers, with suitable compliance and sensitivity for integration in mattresses, pillows, and athletic shoe insoles. With relatively high pressure sensitivity (~0.1 kPa-1) and mechanical robustness, this sensor was able to fulfill a wide variety of roles, including athletic monitoring in an impact mechanics scenario, by recording heel pressure during running and walking, and physiological monitoring, by detecting head position and respiration of a subject lying on a pad and pillow. The sensor detected considerably greater relative signal changes than those reported in recent capacitive sensor studies for heel pressure, and for a comparably minimal, resistive sensor during respiration, in line with its enhanced sensitivity.


Asunto(s)
Atletas , Deportes , Dispositivos Electrónicos Vestibles , Monitoreo Biológico/instrumentación , Monitoreo Fisiológico , Porosidad , Presión , Siliconas
6.
J Laryngol Otol ; 135(3): 276-279, 2021 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-33632351

RESUMEN

BACKGROUND: The occurrence of retained ear mould impression material is rare and can lead to complications. The current case report describes one such complication, where the silicone impression material used to take the impression of the ear canal flowed into the middle ear through the pre-existing tympanic membrane perforation. Five days later, the patient presented with worsened hearing and blood-tinged discharge from the ear. Ear microscopy revealed a greenish foreign body in the middle ear. CASE REPORT: The foreign body was removed by tympanotomy and the perforation repaired using a temporalis fascia graft. A hearing aid was prescribed after ensuring that the perforation had healed. CONCLUSION: It is essential that the audiologist perform a basic otological examination before prescribing a hearing aid and preparing an ear mould. A clinical approach algorithm for audiologists, for prior to taking an impression, is suggested.


Asunto(s)
Oído Medio/lesiones , Cuerpos Extraños/etiología , Audífonos/efectos adversos , Perforación de la Membrana Timpánica/complicaciones , Anciano de 80 o más Años , Femenino , Humanos , Siliconas
7.
Rev Col Bras Cir ; 48: e20202587, 2021.
Artículo en Inglés, Portugués | MEDLINE | ID: mdl-33533824

RESUMEN

OBJECTIVES: the aim of this study was to compare the outcomes of a new silicone vascular prostheses with PTFE vascular prostheses, on a rabbit experimental model. METHODS: forty rabbits underwent infra-renal aorta replacement with 4 mm diameter prostheses, twenty animals with PDMS and twenty animals with PTFE (control group). Retrograde aortic angiography was performed to assess patency. Histological graft samples were examined by electron microscopy to evaluate prostheses endothelialization. RESULTS: patency rates were 100% for both grafts after 30 days; after 60 days, patency rate for PDMS was 92.3% (±7.4), and 73,8% (±13.1) at 90 days. PTFE grafts had patency rates of 87.5% (±11.7) at 60 and 90 days. No statistically significant difference was found in between groups for patency rates (p=0.62). Postoperative complications (death, paraplegia) rates (p=0.526) and aortic clamping times (p=0.299) were comparable in both groups. No statistically significant difference for stenosis was found on angiographical analysis between groups (p=0.650). Electron microscopy revealed limited anastomotic endothelial ingrowth in both prostheses. CONCLUSION: in this experimental model, PDMS and PTFE vascular prostheses had comparable outcomes and PDMS prosthesis could be used as a vascular graft.


Asunto(s)
Aorta/cirugía , Prótesis Vascular , Politetrafluoroetileno/uso terapéutico , Siliconas/uso terapéutico , Animales , Poliésteres , Conejos
8.
Environ Int ; 146: 106261, 2021 01.
Artículo en Inglés | MEDLINE | ID: mdl-33395927

RESUMEN

The ubiquity of organophosphate esters (OPEs) in various environmental matrices inevitably pose human exposure risks. Numerous studies have investigated human exposure pathways to OPEs, including air inhalation, dust ingestion, dermal contact, and dietary and drinking water intake, and have indicated that indoor dust and indoor air routes are frequently the two main human exposure pathways. This article reviews the literature on OPE contamination in indoor air and dust from various microenvironments and on OPE particle size distributions and bioavailability in dust conducted over the past 10 years. Ways in which sampling strategies are related to the uncertainty of exposure assessment results and comparability among different studies in terms of sampling tools, sampling sites, and sample types are addressed. Also, the associations of OPEs in indoor dust/air with human biological samples were summarized. Studies on two emerging matrices, hand wipes and silicone wristbands, are demonstrated to be more comprehensive and accurate in reflecting personal human exposure to OPEs in microenvironments and are summarized. Given the direct application of some diester OPEs (di-OPEs) in numerous products, research on their existence in indoor dust and food and on their effects on human urine are also discussed. Finally, related research trends and avenues for future research are prospected.


Asunto(s)
Contaminación del Aire Interior , Retardadores de Llama , China , Polvo/análisis , Exposición a Riesgos Ambientales/análisis , Monitoreo del Ambiente , Ésteres/análisis , Retardadores de Llama/análisis , Humanos , Organofosfatos/análisis , Siliconas
9.
J Mater Chem B ; 9(5): 1384-1394, 2021 02 07.
Artículo en Inglés | MEDLINE | ID: mdl-33459744

RESUMEN

Silicone elastomer coatings have attracted increasing attention owing to their eco-friendly nature, excellent fouling release ability and drag-reducing property. However, the poor mechanical properties and lack of fouling resistance limit their applications. Herein, a silicone-based polyurethane with 2-ureido-4[1H]-pyrimidinone (UPy) and amphiphilic pendant chains is reported. The UPy groups and urethane can form hydrogen bonds with various substrates so that the coating has significantly improved adhesion strength (0.9-3.0 MPa) compared with the PDMS elastomer (0.3-0.4 MPa). Moreover, the quadruple hydrogen bonding between UPy moieties allows the polymer to have excellent self-healing ability and high elasticity. The modified polymeric coating has low surface energy (24 mJ m-2) and low elastic modulus (1.9 MPa), so it exhibits good fouling release performance. Besides, the amphiphilic side chains can effectively resist protein adsorption and adhesion of the marine bacteria Pseudomonas sp. and diatom Navicula incerta. The novel design can improve the resistance of silicone coating to biofouling and mechanical forces and is promising for high-performance antifouling coatings.


Asunto(s)
Poliuretanos/química , Siliconas/química , Animales , Incrustaciones Biológicas , Peces , Propiedades de Superficie
10.
Environ Int ; 147: 106317, 2021 02.
Artículo en Inglés | MEDLINE | ID: mdl-33341585

RESUMEN

BACKGROUND: Environmental phenols, such as parabens, bisphenol A, and triclosan, are ubiquitous in indoor environments because of their use in packaging, plastics, personal care products, and as anti-microbials. The primary pathways of exposure, as well as habits and behaviors that may lead to greater exposure, are still unclear. OBJECTIVES: Herein, we investigate the relationships between phenols found in residential environments by comparing levels in paired samples of house dust and hand wipes with children's urine. In addition, phenols were analyzed in a novel exposure tool, the silicone wristbands, to investigate which external matrix best correlates with individual exposure based on urinary phenol biomarkers. METHODS: Children aged 3-6 years in central North Carolina, United States, provided paired hand wipe (n = 202), wristband (n = 76), and spot urine samples (n = 180), while legal guardians completed questionnaires on habits and behaviors. House dust samples (n = 186) were collected from the main living area during home visits completed between 2014 and 2016. RESULTS: Environmental phenols were detected frequently in all matrices investigated. Ethyl, methyl, and propylparaben levels observed in hand wipes, dust, and on wristbands were significantly correlated to their associated urinary biomarkers. In addition, intra-paraben correlations were noted, with biomarkers of ethyl, methyl, and propylparabens generally positively and significantly correlated, which suggests co-application of parabens in products. Triclosan levels in dust were positive and significantly correlated with levels in hand wipes and wristbands and with urinary concentrations, suggesting non-personal care product sources may be important in children's overall triclosan exposure. Generally, chemicals on wristbands were more highly correlated with urinary biomarkers than with chemicals in hand wipes or house dust. In addition, more frequent lotion use was positively associated with urinary concentrations of paraben biomarkers. CONCLUSIONS: Our results suggest that the home environment is an important source of exposure which has been under-investigated for some environmental phenols (e.g., triclosan in house dust). Associations between wristbands and biomarkers of exposure, which were stronger than for hand wipes and house dust, suggest that silicone wristbands may provide a suitable exposure assessment tool for some phenols.


Asunto(s)
Polvo , Siliconas , Biomarcadores , Niño , Preescolar , Polvo/análisis , Exposición a Riesgos Ambientales/análisis , Monitoreo del Ambiente , Humanos , North Carolina , Parabenos/análisis , Fenoles
11.
Rev. Asoc. Odontol. Argent ; 108(3): 113-118, dic. 2020. ilus
Artículo en Español | LILACS | ID: biblio-1147645

RESUMEN

Objetivo: Analizar cualitativamente la biocompatibilidad y la capacidad osteogénica de dos selladores endodónticos a base de silicato de calcio: el biocerámico Bio-C Sealer (BIOc) y MTA Densell Sealer (MTAd). Materiales y métodos: En la tibia izquierda de 30 ratas Wistar macho se implantó un tubo de silicona obturado con BIOc. De igual forma, en la tibia derecha de cada una se implantó un tubo de silicona obturado con MTAd. Los animales fueron eutanasiados en grupos de 10 a los 7, 30 y 90 días. Las tibias fueron procesadas para su análisis histológico y analizadas con microscopía óptica. Según lo observado, fueron clasificadas en tres categorías: 1: Presencia de cápsula fibrosa sana y neoformación ósea, sin células inflamatorias; 2: Cápsula fibrosa con o sin células inflamatorias, formación inicial de trabéculas óseas y presencia de células inflamatorias en los tejidos circundantes; 3: Ausencia de cápsula y/o tejido óseo y presencia de numerosas células inflamatorias. Los resultados fueron analizados con las pruebas de McNemar y de Kruskal-Wallis (P<0,05). Resultados: A los 7 días, los tejidos en contacto con BIOc y MTAd reaccionaron según la categoría 3. A los 30 días, todos los casos correspondieron a la categoría 2. A los 90 días, los 10 implantes de BIOc fueron clasificados según la categoría 1. MTAd presentó nueve casos de categoría 1 y un caso de categoría 2. No hubo diferencias significativas entre ambos selladores dentro de cada uno de los períodos de observación (P>0,05), pero sí las hubo cuando se compararon los resultados obtenidos entre períodos de observación (P<0,05). Conclusión: Al finalizar el ensayo, Bio-C Sealer y MTA Densell Sealer se comportaron como materiales biocompatibles y osteogénicos en tibias de rata (AU)


Aim: To analyze the biocompatibility and osteogenic capacity of two silicate-based endodontic sealers, the bioceramic Bio C-Sealer (BIOc) and the MTA-based sealer MTA Densell (MTAd). Materials and methods: Silicone tubes filled with BIOc were implanted in the left tibias of 30 white male Wistar rats (one per tibia). In similar fashion, tubes filled with MTAd were implanted in the right tibias. The animals were euthanized in groups of 10 at 7, 30 and 90 days postoperatively. The tibias were removed, processed for histology and analysed under optical microscopy. The observations were classified in three categories: 1: Presence of a healthy fibrous capsule and newly formed bone trabeculae without inflammatory cells. 2: Fibrous capsule with or without inflammatory cells, initial formation of bone trabeculae and presence of inflammatory cells in the surrounding tissues. 3: Absence of a fibrous capsule and/or bone formation with the presence of numerous inflammatory cells. Data was analyzed by the McNemar and the Kruskal-Wallis test (P<0.05). Results: At 7 days: The tissues in contact with BIOc and MTAd reacted as category 3. At 30 days: All cases were classified as category 2. At 90 days: All BIOc cases were in category 1 while MTAd presented nine cases of category 1 and one case of category 2. There were no significant differences (P>0.05) between both sealants BIOc and MTAd in each period group. However, there were significant differences (P<0.05) when the results between periods were compared. Conclusion: At the end of the experiment both, BIOc and MTAd behaved as biocompatible and osteogenic materials in the rats' tibias (AU)


Asunto(s)
Animales , Ratas , Materiales de Obturación del Conducto Radicular , Materiales Biocompatibles , Cerámica , Osteogénesis , Siliconas , Ensayo de Materiales , Calcarea Silicata , Ratas Wistar , Silicatos , Microscopía
12.
PLoS One ; 15(12): e0242704, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-33351854

RESUMEN

In this study we present a kinematic approach for modeling needle insertion into soft tissues. The kinematic approach allows the presentation of the problem as Dirichlet-type (i.e. driven by enforced motion of boundaries) and therefore weakly sensitive to unknown properties of the tissues and needle-tissue interaction. The parameters used in the kinematic approach are straightforward to determine from images. Our method uses Meshless Total Lagrangian Explicit Dynamics (MTLED) method to compute soft tissue deformations. The proposed scheme was validated against experiments of needle insertion into silicone gel samples. We also present a simulation of needle insertion into the brain demonstrating the method's insensitivity to assumed mechanical properties of tissue.


Asunto(s)
Inyecciones/estadística & datos numéricos , Modelos Estadísticos , Agujas , Siliconas/análisis , Fenómenos Biomecánicos , Encéfalo/anatomía & histología , Simulación por Computador , Humanos , Inyecciones/instrumentación , Inyecciones/métodos , Maniquíes , Modelos Anatómicos , Siliconas/química , Estrés Mecánico
13.
J Vis Exp ; (166)2020 12 04.
Artículo en Inglés | MEDLINE | ID: mdl-33346198

RESUMEN

External forces are an important factor in tissue formation, development, and maintenance. The effects of these forces are often studied using specialized in vitro stretching methods. Various available systems use 2D substrate-based stretchers, while the accessibility of 3D techniques to strain soft hydrogels, is more restricted. Here, we describe a method that allows external stretching of soft hydrogels from their circumference, using an elastic silicone strip as the sample carrier. The stretching system utilized in this protocol is constructed from 3D-printed parts and low-cost electronics, making it simple and easy to replicate in other labs. The experimental process begins with polymerizing thick (>100 µm) soft fibrin hydrogels (Elastic Modulus of ~100 Pa) in a cut-out at the center of a silicone strip. Silicone-gel constructs are then attached to the printed-stretching device and placed on the confocal microscope stage. Under live microscopy the stretching device is activated, and the gels are imaged at various stretch magnitudes. Image processing is then used to quantify the resulting gel deformations, demonstrating relatively homogenous strains and fiber alignment throughout the gel's 3D thickness (Z-axis). Advantages of this method include the ability to strain extremely soft hydrogels in 3D while executing in situ microscopy, and the freedom to manipulate the geometry and size of the sample according to the user's needs. Additionally, with proper adaptation, this method can be used to stretch other types of hydrogels (e.g., collagen, polyacrylamide or polyethylene glycol) and can allow for analysis of cells and tissue response to external forces under more biomimetic 3D conditions.


Asunto(s)
Hidrogeles/química , Imagenología Tridimensional , Microscopía , Módulo de Elasticidad , Fibrina/química , Fibrinógeno/química , Análisis de Elementos Finitos , Polimerizacion , Siliconas/química , Programas Informáticos , Trombina/química , Interfaz Usuario-Computador
14.
PLoS One ; 15(12): e0244518, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-33370781

RESUMEN

Spread of pathogens on contaminated surfaces plays a key role in disease transmission. Surface technologies that control pathogen transfer can help control fomite transmission and are of great interest to public health. Here, we report a novel bead transfer method for evaluating fomite transmission in common laboratory settings. We show that this method meets several important criteria for quantitative test methods, including reasonableness, relevancy, resemblance, responsiveness, and repeatability, and therefore may be adaptable for standardization. In addition, this method can be applied to a wide variety of pathogens including bacteria, phage, and human viruses. Using the bead transfer method, we demonstrate that an engineered micropattern limits transfer of Staphylococcus aureus by 97.8% and T4 bacteriophage by 93.0% on silicone surfaces. Furthermore, the micropattern significantly reduces transfer of influenza B virus and human coronavirus on silicone and polypropylene surfaces. Our results highlight the potential of using surface texture as a valuable new strategy in combating infectious diseases.


Asunto(s)
Bacteriófago T4/patogenicidad , Bacteriófagos/patogenicidad , Coronavirus/patogenicidad , Virus de la Influenza B/patogenicidad , Infecciones Estafilocócicas/terapia , Staphylococcus aureus/patogenicidad , Infecciones por Coronavirus/transmisión , Infecciones por Coronavirus/virología , Fómites/microbiología , Fómites/virología , Humanos , Gripe Humana/transmisión , Gripe Humana/virología , Siliconas
15.
Facial Plast Surg ; 36(5): 517-527, 2020 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-33368076

RESUMEN

In Asian countries, augmentation rhinoplasty is especially common, where alloplastic implants are used much more commonly than autologous tissues. In rhinoplasty, such artificial materials include silicone, expanded polytetrafluoroethylene (ePTFE), porous high-density polyethylene (pHDPE), and acellular human dermis. As the use of implants has become increasingly common in rhinoplasty, more adverse effects such as infection, extrusion, movement, irregularities, absorption, prolonged swelling, seroma, and contracture have been recognized and reported in the literature. Surgeons should be able to recognize these probable complications and manage them successfully. Early detection and prompt management of the complication are essential for minimizing the severity of the deformity. Proper management of complications is key for the success of dorsal augmentation using alloplastic implants.


Asunto(s)
Implantes Dentales , Rinoplastia , Materiales Biocompatibles/efectos adversos , Humanos , Politetrafluoroetileno/efectos adversos , Prótesis e Implantes/efectos adversos , Rinoplastia/efectos adversos , Siliconas/efectos adversos
16.
Medicine (Baltimore) ; 99(45): e23073, 2020 Nov 06.
Artículo en Inglés | MEDLINE | ID: mdl-33157970

RESUMEN

INTRODUCTION: Contracture of dacryocyst by an implanted lacrimal silicone tube is rare. This report describes a unique case of secondary dacryocystitis and the contracture of dacryocyst caused by a lacrimal silicone tube that was placed in the lacrimal system for 10 years. PATIENT CONCERNS: A 63-year-old female was diagnosed with chronic dacryocystitis at a local hospital and underwent surgical treatment 10 years ago. In the past month, the patient complained of persistent tearing and purulent secretion from the eyes. DIAGNOSIS: The patient was diagnosed with secondary dacryocystitis, based on clinical features and the presence of the silicone stent, granulation tissue formation, and dacryocyst contracture in the lacrimal duct, as observed by nasal endoscopy. INTERVENTIONS: For treatment, the implanted silicone tube in the patient was removed, the lacrimal duct and nasal mucosa was anastomosed, and a new lacrimal silicone tube was placed again. OUTCOMES: Following the surgery, the patient recounted that there were no symptoms, and follow-up examinations performed over a 1-month period posttreatment revealed no recurrence of obstruction or dacryocystitis. Therefore, the surgeon removed the lacrimal drainage tube and asked the patient to return to the outpatient department regularly for examination. CONCLUSION: The findings, in this case, suggest that silicone tubes are safe and effective, and can be placed in the lacrimal drainage system. However, in this patient, prolonged intubation caused chronic inflammation, granulation tissue formation, and dacryocyst contracture. Our findings could inform surgeons to consider the reasonable duration of intubation for treating cases of lacrimal obstruction, in order to avoid unnecessary complications.


Asunto(s)
Dacriocistitis/etiología , Conducto Nasolagrimal/cirugía , Complicaciones Posoperatorias/etiología , Prótesis e Implantes/efectos adversos , Femenino , Humanos , Persona de Mediana Edad , Diseño de Prótesis , Siliconas , Factores de Tiempo
17.
Medicine (Baltimore) ; 99(41): e22548, 2020 Oct 09.
Artículo en Inglés | MEDLINE | ID: mdl-33031299

RESUMEN

OBJECTIVE: To investigate the efficacy and complications that might be associated with pyrocarbon compared with silicone in patients undergoing joint replacement surgery. METHODS: The full-text papers about the clinical efficacy of pyrocarbon and silicone were retrieved from multiple databases. Review Manager version 5.0 was adopted for meta-analysis and analyses of sensitivity and bias. RESULTS: Ultimately, we studied 232 patients across eight studies that met the eligibility criteria. The meta-analysis suggested a significant difference between the pyrocarbon and silicone groups in terms of the Disabilities of the Arm, Shoulder, and Hand (DASH) score (standard mean difference (SMD) = 1.48; 95% CI [0.97, 1.99]; P = .009; P for Heterogeneity <0.00001; I = 63%); Visual Analogue Score (VAS) (SMD = 1.68; 95% CI [1.36, 1.99]; P < .00001; P for heterogeneity = 0.01; I = 61%), and the abnormal radiolucent line (RR = 6.66; 95% CI [3.19, 13.89]; P < .00001; P for heterogeneity = 0.87, I = 0%); and ossification development (RR = 0.90; 95% CI [0.56, 1.44], P = .66; P for heterogeneity = 0.94, I = 0%). CONCLUSION: This study showed that pyrocarbon might be an efficient material compared with silicone for joint replacement surgery, but resulted in poorer functional and pain outcomes compared with silicone.


Asunto(s)
Artroplastia de Reemplazo , Carbono , Prótesis Articulares , Siliconas , Materiales Biocompatibles , Evaluación de la Discapacidad , Humanos , Dimensión del Dolor , Diseño de Prótesis
18.
Praxis (Bern 1994) ; 109(14): 1127-1133, 2020.
Artículo en Alemán | MEDLINE | ID: mdl-33109001

RESUMEN

Cosmetic Breast Augmentation without Silicone Implants Abstract. Cosmetic breast augmentation procedures without silicone implants are becoming increasingly popular. Mastopexy can be adapted to the needs of the patient and usually result in an at least optical augmentation. Lipofilling is a safe procedure in reconstructive and aesthetic breast surgery and can help to restore natural appearance, compensate volume deficiencies, and correct asymmetries, that may be congenital or a consequence of prior surgeries. Cosmetic breast augmentation of very small breasts or when aiming at higher breast volumes using lipofilling only are usually combined with procedures for tissue expansion in order to increase the take rate of the injected fat. Hyaluronic acid injections is no valid alternative and are not recommended for cosmetic breast augmentation.


Asunto(s)
Mamoplastia , Mastectomía , Satisfacción del Paciente , Mama/cirugía , Humanos , Siliconas
19.
J Urol ; 204(4): 776-777, 2020 10.
Artículo en Inglés | MEDLINE | ID: mdl-32898972
20.
J Urol ; 204(4): 776, 2020 10.
Artículo en Inglés | MEDLINE | ID: mdl-32898973
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