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1.
Recurso de Internet en Portugués | LIS - Localizador de Información en Salud | ID: lis-47889

RESUMEN

Edição número 26/2020 do SBP AmamentAÇÃO – informativo anual da Sociedade Brasileira de Pediatria (SBP) – disponível para leitura no site instituição e traz um resumo das ações da SBP e suas filiadas em prol da promoção, proteção e apoio ao aleitamento materno durante a Semana Mundial de Aleitamento Materno (SMAM) e Agosto Dourado. O editorial aborda a manutenção da amamentação em tempos de pandemia de Covid-19. No texto, ela esclarece a dúvida comum entre as mães que testam positivo para a doença e se há risco de contaminação da criança pelo leite materno. Na sessão, Pergunte ao Especialista, profissionais da SBP esclarecem dúvidas frequentes sobre o aleitamento materno.


Asunto(s)
Lactancia Materna , Promoción de la Salud , Infecciones por Coronavirus/transmisión , Transmisión Vertical de Enfermedad Infecciosa/prevención & control , Leche Humana
2.
Recurso de Internet en Portugués | LIS - Localizador de Información en Salud | ID: lis-47831

RESUMEN

Uma revisão sistemática das evidências científicas disponíveis feita pela Organização Pan-Americana da Saúde (OPAS) e pela Organização Mundial da Saúde (OMS) revela que as recomendações sobre o contato mãe-bebê e aleitamento materno devem se basear em uma consideração ampla, não apenas nos riscos potenciais da COVID-19 para o bebê, mas também dos riscos de morbidade e mortalidade associados ao não aleitamento e uso inapropriado de fórmulas infantis.


Asunto(s)
Lactancia Materna , Transmisión Vertical de Enfermedad Infecciosa/prevención & control , Infecciones por Coronavirus , Betacoronavirus , Promoción de la Salud
3.
Am J Perinatol ; 37(S 02): S46-S53, 2020 09.
Artículo en Inglés | MEDLINE | ID: mdl-32898882

RESUMEN

OBJECTIVE: We aimed at reviewing the currently available guidelines and scientific recommendations regarding the neonatal in-hospital management and feeding in the light of the coronavirus disease 2019 (COVID-19) pandemic. STUDY DESIGN: We systematically searched the guideline databases, Medline, Embase, and nationale/international neonatal societies websites as of June 19, 2020, for guidelines on neonatal management and feeding during the COVID-19 pandemic, at the same time assessing the methodological quality using the Appraisal of Guidelines for Research and Evaluation II tool. RESULTS: Eleven guidelines were included. The Chinese and American recommendations suggest separation of the mother and her neonate, whereas in French, Italian, UK, Canadian, and World Health Organization consensus documents the rooming-in is suggested, with Centers for Disease Control and Prevention guidelines suggesting to decide on a case-by-case basis. All the guidelines recommend breastfeeding or feeding with expressed maternal milk; the only exception is the Chinese recommendations, these last suggesting to avoid breastfeeding. CONCLUSION: This review may provide a useful tool for clinicians and organizers, highlighting differences and similarities of the existing guidelines on the management and feeding strategies in the light of the COVID-19 pandemic. KEY POINTS: · This study compares guidelines on management and nutrition of a newborn born to a mother with SARS-CoV-2 infection.. · Existing guidelines on neonatal management and nutrition during the SARS-CoV-2 pandemic show many differences.. · The majority of recommendations are mainly based on experts' opinion and are not evidence-based..


Asunto(s)
Lactancia Materna/estadística & datos numéricos , Infecciones por Coronavirus/epidemiología , Fenómenos Fisiológicos Nutricionales del Lactante , Neumonía Viral/epidemiología , Guías de Práctica Clínica como Asunto , Femenino , Humanos , Recién Nacido , Transmisión Vertical de Enfermedad Infecciosa/prevención & control , Leche Humana , Pandemias , Organización Mundial de la Salud
4.
BMJ Case Rep ; 13(9)2020 Sep 02.
Artículo en Inglés | MEDLINE | ID: mdl-32878840

RESUMEN

The COVID-19 outbreak has spread across the globe at an alarming rate. As the pandemic escalates, experience of COVID-19 in pregnant women is accumulating. We present a case of COVID-19 pneumonia in a 28-week pregnant woman with a known low lying placenta. The patient had deranged liver function tests at presentation, along with elevated bile acids. We discuss the differential diagnosis of these findings, and the possible mechanisms of hepatic injury in COVID-19. The low lying placenta in this patient meant that we had to carefully consider the application of recommendations for thromboprophylaxis in pregnant COVID-19 patients. With supportive management, this patient improved enough to be discharged, and has gone on to deliver a healthy neonate at term.


Asunto(s)
Colestasis/diagnóstico , Infecciones por Coronavirus/diagnóstico , Neumonía Viral/diagnóstico , Complicaciones Infecciosas del Embarazo/diagnóstico , Tercer Trimestre del Embarazo , Adulto , Colestasis/complicaciones , Infecciones por Coronavirus/complicaciones , Femenino , Humanos , Transmisión Vertical de Enfermedad Infecciosa/prevención & control , Pandemias , Neumonía Viral/complicaciones , Embarazo , Resultado del Embarazo
5.
Dan Med J ; 67(9)2020 Aug 18.
Artículo en Inglés | MEDLINE | ID: mdl-32829745

RESUMEN

INTRODUCTION: The coronavirus disease 19 (COVID-19) pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), progresses globally, and means to reduce the transmission are needed. In the community, the use of face masks is increasing world-wide, but documentation for the efficacy of this remedy is lacking. This trial investigates whether the use of face masks in the community will reduce wearers' risk of SARS-CoV-2 infection. METHODS: This study will be a two-arm, unblinded, randomised controlled trial. We will include adults (>18 years of age) without prior confirmed COVID-19 or symptoms suggestive of COVID-19, who spend more than three hours per day outside the home with exposure to other people. A total of 6,000 participants are randomly assigned 1:1 to use face masks or not for a 30-day period during the pandemic. Participants will perform self-testing; quick test for SARS-CoV-2 antibodies (immunoglobulin M (IgM) and immunoglobulin G (IgG)) (the Livzon lateral flow test) and oropharyngeal/nasal swabs for viral detection using polymerase chain reaction (PCR). The primary endpoint following the 30-day study period is the difference in the number of SARS-CoV-2-infected individuals between the two study groups as assessed by a positive nasopharyngeal swap, a positive antibody test or a hospital-based diagnosis of SARS-CoV-2 infection. CONCLUSIONS: We will study whether a face mask protects the wearer of the mask against SARS-CoV-2 infection. The findings are expected to apply to the present pandemic and to future viral outbreaks and to provide evidence for authority recommendations across the world. FUNDING: This study was funded by Salling Fondene. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT04337541.


Asunto(s)
Control de Enfermedades Transmisibles/métodos , Infecciones por Coronavirus/prevención & control , Transmisión Vertical de Enfermedad Infecciosa/prevención & control , Máscaras/estadística & datos numéricos , Pandemias/prevención & control , Neumonía Viral/prevención & control , Salud Pública , Adulto , Anciano , Dinamarca , Femenino , Humanos , Incidencia , Masculino , Persona de Mediana Edad , Prevención Primaria/instrumentación , Prevención Primaria/métodos , Medición de Riesgo , Organización Mundial de la Salud
6.
Ginekol Pol ; 91(7): 417-423, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32779163

RESUMEN

The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become the reason of the global health crisis. Since the first case of diagnosed COVID-19 pneumonia was reported in Wuhan, Hubei Province, China, in December 2019, the infection has spread rapidly to all over the world. The knowledge gained from previous human coronavirus infection outbreaks suggests that pregnant women and their foetuses represent a high-risk population during infectious disease epidemics. Moreover, a pregnancy, due to the physiological changes involving immune and cardiopulmonary systems, is a state predisposing women to respiratory complications of viral infection. The constantly increasing number of publications regarding the course of COVID-19 infection in pregnant women has been published, however, the available data remains limited and many questions remain unanswered. The aim of this review was to summarize the literature data and adjusted to current recommendations regarding pregnancy care, delivery and postpartum period. An extremely important issue is the need to register all the cases of COVID-19 affected women and the course of these pregnancies to local, regional, or international registries, which will be helpful to answer many clinical and scientific questions and to create guidelines ensuring an adequate level of care for women affected by COVID-19 infection during pregnancy, delivery and during postpartum period, as well as their newborns.


Asunto(s)
Infecciones por Coronavirus , Transmisión Vertical de Enfermedad Infecciosa/prevención & control , Pandemias , Neumonía Viral , Complicaciones Infecciosas del Embarazo , Betacoronavirus , Infecciones por Coronavirus/epidemiología , Infecciones por Coronavirus/fisiopatología , Infecciones por Coronavirus/terapia , Femenino , Humanos , Manejo de Atención al Paciente/métodos , Neumonía Viral/epidemiología , Neumonía Viral/fisiopatología , Neumonía Viral/terapia , Embarazo , Complicaciones Infecciosas del Embarazo/epidemiología , Complicaciones Infecciosas del Embarazo/fisiopatología , Complicaciones Infecciosas del Embarazo/terapia , Resultado del Embarazo/epidemiología
7.
Am J Perinatol ; 37(S 02): S31-S38, 2020 09.
Artículo en Inglés | MEDLINE | ID: mdl-32757186

RESUMEN

In spite of the increasing, accumulating knowledge on the novel pandemic coronavirus severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), questions on the coronavirus disease-2019 (COVID-19) infection transmission from mothers to fetuses or neonates during pregnancy and peripartum period remain pending and have not been addressed so far. SARS-CoV-2, a RNA single-stranded virus, has been detected in the amniotic fluid, in the cord blood and in the placentas of the infected women. In the light of these findings, the theoretical risk of intrauterine infection for fetuses, or of peripartum infection occurring during delivery for neonates, has a biological plausibility. The extent of this putative risk might, however, vary during the different stages of pregnancy, owing to several variables (physiological modifications of the placenta, virus receptors' expression, or delivery route). This brief review provides an overview of the current evidence in this area. Further data, based on national and international multicenter registries, are needed not only to clearly assess the extent of the risk for vertical transmission, but also to ultimately establish solid guidelines and consistent recommendations. KEY POINTS: · Questions on the COVID-19 infection transmission from mothers to fetuses or neonates during pregnancy and peripartum period remain pending so far.. · The theoretical risk of intrauterine infection for fetuses, or of neonatal infection during delivery for neonates, has a biological plausibility.. · A caution is recommended in the interpretation of clinical and laboratory data in neonates..


Asunto(s)
Infecciones por Coronavirus/prevención & control , Transmisión Vertical de Enfermedad Infecciosa/prevención & control , Pandemias/prevención & control , Neumonía Viral/prevención & control , Atención Posnatal/métodos , Complicaciones Infecciosas del Embarazo/prevención & control , Betacoronavirus , Parto Obstétrico , Femenino , Humanos , Recién Nacido , Embarazo
9.
Public Health Rep ; 135(1_suppl): 182S-188S, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32735204

RESUMEN

OBJECTIVES: We evaluated the impact of a 2014 New York City health code change requiring laboratories to indicate if a patient is pregnant or probably pregnant in the electronic laboratory report (ELR) when reporting syphilis and hepatitis B virus (HBV) cases to the New York City Department of Health and Mental Hygiene (DOHMH). METHODS: We calculated the number of pregnant persons with syphilis or HBV infection reported to DOHMH from January 1, 2013, through June 30, 2018. We compared the proportion in which the first report to DOHMH was an ELR with pregnancy indicated before and after the policy change. We calculated time between first ELR with pregnancy indicated and subsequent reporting by a method other than ELR and the proportion of cases in which ELR with pregnancy indicated was the only report source. RESULTS: A total of 552 new syphilis and 8414 HBV-infected cases were reported to DOHMH. From January 2013-June 2014 (pre-change) to January 2017-June 2018 (post-change), the proportion of cases in which ELR with pregnancy indicated was the first report to DOHMH increased significantly (14.7% [23/156] to 46.2% [80/173] for syphilis; 8.0% [200/2498] to 45.3% [851/1879] for HBV infection [P < .001]). Median time between first ELR with pregnancy indicated and subsequent reporting by a method other than ELR was 9.0 days for syphilis and 51.0 days for HBV infection. ELR with pregnancy indicated was the only report for 43.1% (238/552) of syphilis cases and 23.4% (1452/6200) of HBV cases during the study period. CONCLUSION: Including pregnancy status with ELR can increase the ability of public health departments to conduct timely interventions to prevent mother-to-child transmission.


Asunto(s)
Hepatitis B/diagnóstico , Complicaciones Infecciosas del Embarazo/diagnóstico , Vigilancia en Salud Pública/métodos , Sífilis/diagnóstico , Adolescente , Adulto , Femenino , Humanos , Transmisión Vertical de Enfermedad Infecciosa/prevención & control , Ciudad de Nueva York , Embarazo , Complicaciones Infecciosas del Embarazo/prevención & control , Adulto Joven
10.
Lancet HIV ; 7(9): e629-e640, 2020 09.
Artículo en Inglés | MEDLINE | ID: mdl-32771089

RESUMEN

BACKGROUND: The COVID-19 pandemic could lead to disruptions to provision of HIV services for people living with HIV and those at risk of acquiring HIV in sub-Saharan Africa, where UNAIDS estimated that more than two-thirds of the approximately 38 million people living with HIV resided in 2018. We aimed to predict the potential effects of such disruptions on HIV-related deaths and new infections in sub-Saharan Africa. METHODS: In this modelling study, we used five well described models of HIV epidemics (Goals, Optima HIV, HIV Synthesis, an Imperial College London model, and Epidemiological MODeling software [EMOD]) to estimate the effect of various potential disruptions to HIV prevention, testing, and treatment services on HIV-related deaths and new infections in sub-Saharan Africa lasting 6 months over 1 year from April 1, 2020. We considered scenarios in which disruptions affected 20%, 50%, and 100% of the population. FINDINGS: A 6-month interruption of supply of antiretroviral therapy (ART) drugs across 50% of the population of people living with HIV who are on treatment would be expected to lead to a 1·63 times (median across models; range 1·39-1·87) increase in HIV-related deaths over a 1-year period compared with no disruption. In sub-Saharan Africa, this increase amounts to a median excess of HIV deaths, across all model estimates, of 296 000 (range 229 023-420 000) if such a high level of disruption occurred. Interruption of ART would increase mother-to-child transmission of HIV by approximately 1·6 times. Although an interruption in the supply of ART drugs would have the largest impact of any potential disruptions, effects of poorer clinical care due to overstretched health facilities, interruptions of supply of other drugs such as co-trimoxazole, and suspension of HIV testing would all have a substantial effect on population-level mortality (up to a 1·06 times increase in HIV-related deaths over a 1-year period due to disruptions affecting 50% of the population compared with no disruption). Interruption to condom supplies and peer education would make populations more susceptible to increases in HIV incidence, although physical distancing measures could lead to reductions in risky sexual behaviour (up to 1·19 times increase in new HIV infections over a 1-year period if 50% of people are affected). INTERPRETATION: During the COVID-19 pandemic, the primary priority for governments, donors, suppliers, and communities should focus on maintaining uninterrupted supply of ART drugs for people with HIV to avoid additional HIV-related deaths. The provision of other HIV prevention measures is also important to prevent any increase in HIV incidence. FUNDING: Bill & Melinda Gates Foundation.


Asunto(s)
Fármacos Anti-VIH/provisión & distribución , Betacoronavirus/patogenicidad , Infecciones por Coronavirus/epidemiología , Infecciones por VIH/epidemiología , Modelos Estadísticos , Pandemias , Neumonía Viral/epidemiología , África del Sur del Sahara/epidemiología , Fármacos Anti-VIH/uso terapéutico , Terapia Antirretroviral Altamente Activa , Condones/provisión & distribución , Infecciones por Coronavirus/mortalidad , Infecciones por Coronavirus/transmisión , Infecciones por Coronavirus/virología , Femenino , Salud Global/tendencias , Infecciones por VIH/mortalidad , Infecciones por VIH/transmisión , Infecciones por VIH/virología , VIH-1/efectos de los fármacos , VIH-1/crecimiento & desarrollo , Humanos , Incidencia , Recién Nacido , Transmisión Vertical de Enfermedad Infecciosa/prevención & control , Transmisión Vertical de Enfermedad Infecciosa/estadística & datos numéricos , Masculino , Neumonía Viral/mortalidad , Neumonía Viral/transmisión , Neumonía Viral/virología , Conducta Sexual/psicología , Conducta Sexual/estadística & datos numéricos , Análisis de Supervivencia
11.
Z Geburtshilfe Neonatol ; 224(4): 181-186, 2020 08.
Artículo en Alemán | MEDLINE | ID: mdl-32838447

RESUMEN

The novel coronavirus SARS-CoV-2 has developed into a pandemic, yet still has many unknowns. The modalities of transmission, different symptoms and manifestations as well as concomitant circumstances of the disease are insufficiently characterized. Especially patient groups in special situations like pregnant women and newborns have to be considered separately. The current knowledge about pregnancy, labor and the first days of life is characterized by particular uncertainty due to the scarce data available. However, there is currently no evidence of significant unfavorable maternal and perinatal outcome. Many pregnant women with SARS-CoV-2 infection remain asymptomatic. The possibility of vertical transmission to the child cannot be excluded with certainty. However, indications of vertical transmission were detected only in individual cases. Newborn infections are also rather rare, unspecific and usually mild, with respiratory symptoms dominating. In this article, the data available to date are examined in order to provide better information, advice and treatment for pregnant women and newborns with SARS-CoV-2 and to provide suggestions for future research.


Asunto(s)
Infecciones por Coronavirus/prevención & control , Transmisión Vertical de Enfermedad Infecciosa/prevención & control , Pandemias , Atención Perinatal , Neumonía Viral/prevención & control , Complicaciones Infecciosas del Embarazo/virología , Betacoronavirus , Niño , Infecciones por Coronavirus/epidemiología , Femenino , Humanos , Recién Nacido , Neumonía Viral/epidemiología , Embarazo
12.
Z Geburtshilfe Neonatol ; 224(4): 217-222, 2020 08.
Artículo en Alemán | MEDLINE | ID: mdl-32838449

RESUMEN

With begin of the SARS-CoV-2 pandemic the german obstetric, peri-/neonatological and pediatric professional societies published recommendations for care of pregnant and newborn, as well as for necessary staff protection in March 2020 [1-3]. Because of the rapid emerging increase of knowledge an update is required. This work therefore perceives as prosecution of the existing recommendations [1-3].Worldwide national recommendations were recently compared and published in a consensual review [4]. In methodological dependence this update of recommendations comments on key questions of pre-, peri- and postnatal care at SARS-CoV-2 and COVID-19, based on publications up to 30.05.2020. Statements represent a carefully concerned expert consensus and can change contemporary as new knowledge appears.The responsibility for concrete management remains at the local medical team, decisions should be supported by these recommendations.


Asunto(s)
Betacoronavirus , Infecciones por Coronavirus/prevención & control , Transmisión Vertical de Enfermedad Infecciosa/prevención & control , Pandemias , Neumonía Viral/prevención & control , Guías de Práctica Clínica como Asunto , Complicaciones Infecciosas del Embarazo/virología , Niño , Infecciones por Coronavirus/epidemiología , Femenino , Humanos , Recién Nacido , Neumonía Viral/epidemiología , Embarazo
14.
Lancet HIV ; 7(8): e582-e592, 2020 08.
Artículo en Inglés | MEDLINE | ID: mdl-32763221

RESUMEN

Pregnancy is a high-risk period for HIV acquisition in African women, and pregnant women who become acutely infected with HIV account for up to a third of vertical HIV transmission cases in African settings. To protect women and eliminate vertical transmission, WHO recommends offering oral pre-exposure prophylaxis (PrEP) based on tenofovir to HIV-negative pregnant and post-partum women with a substantial risk of HIV acquisition. PrEP implementation for pregnant and post-partum women lags behind implementation for other high-risk populations. Unique considerations for PrEP implementation arise during pregnancy and post partum, including the integration of provider training with clinical delivery and monitoring of PrEP exposure and outcomes within existing maternal health systems, yet scarce implementation data are available to generate evidence in this context.


Asunto(s)
Fármacos Anti-VIH/administración & dosificación , Infecciones por VIH/prevención & control , Profilaxis Pre-Exposición , Fármacos Anti-VIH/uso terapéutico , Femenino , Implementación de Plan de Salud , Humanos , Transmisión Vertical de Enfermedad Infecciosa/prevención & control , Masculino , Atención Posnatal , Embarazo
15.
New Jersey; BMJ Best Practice; Ago. 6, 2020. 194 p.
Monografía en Inglés | BIGG | ID: biblio-1116708

RESUMEN

A potentially severe acute respiratory infection caused by the novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).[1] The clinical presentation is generally that of a respiratory infection with a symptom severity ranging from a mild common cold-like illness, to a severe viral pneumonia leading to acute respiratory distress syndrome that is potentially fatal. Characteristic symptoms include fever, cough, and dyspnea, although some patients may be asymptomatic. Complications of severe disease include, but are not limited to, multi-organ failure, septic shock, and blood clots.


Asunto(s)
Humanos , Masculino , Femenino , Embarazo , Recién Nacido , Lactante , Preescolar , Niño , Adolescente , Adulto , Persona de Mediana Edad , Anciano , Anciano de 80 o más Años , Neumonía Viral/complicaciones , Neumonía Viral/tratamiento farmacológico , Neumonía Viral/diagnóstico por imagen , Grupos de Riesgo , Portador Sano/transmisión , Personal de Salud/organización & administración , Infecciones por Coronavirus/complicaciones , Infecciones por Coronavirus/tratamiento farmacológico , Infecciones por Coronavirus/diagnóstico por imagen , Transmisión Vertical de Enfermedad Infecciosa/prevención & control , Pandemias/estadística & datos numéricos , Brote de los Síntomas , Betacoronavirus/patogenicidad , Neumonía Asociada a la Atención Médica/diagnóstico , China/epidemiología
17.
Breastfeed Med ; 15(8): 488-491, 2020 08.
Artículo en Inglés | MEDLINE | ID: mdl-32614251

RESUMEN

Background: Limited data are available on the perinatal and postnatal transmission of novel coronavirus disease 2019 (COVID-19). The Centers for Disease Control and Prevention (CDC) and World Health Organization (WHO) recommended breastfeeding with necessary precautions to mothers with COVID-19. Case Presentation: A 20-year-old pregnant woman with no symptoms of COVID-19 presented to the hospital for delivery at 39 weeks of gestation. She was tested for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) by reverse transcriptase polymerase chain reaction (RT-PCR) because her father had been diagnosed with COVID-19. A nasopharyngeal swab RT-PCR test was positive for SARS-CoV-2. Therefore, the baby and the mother were cared for separately after delivery. Breast milk obtained after first lactation was tested by real-time RT-PCR and was positive for SARS-CoV-2. Conclusions: In this article, we aimed to report the presence of SARS-CoV-2 in breast milk. Although further studies are needed, this situation may have an impact on breastfeeding recommendations.


Asunto(s)
Betacoronavirus/aislamiento & purificación , Lactancia Materna , Infecciones por Coronavirus , Transmisión Vertical de Enfermedad Infecciosa/prevención & control , Leche Humana/virología , Pandemias , Neumonía Viral , Complicaciones Infecciosas del Embarazo , Adulto , Enfermedades Asintomáticas/terapia , Lactancia Materna/efectos adversos , Lactancia Materna/métodos , Técnicas de Laboratorio Clínico/métodos , Infecciones por Coronavirus/diagnóstico , Infecciones por Coronavirus/fisiopatología , Infecciones por Coronavirus/prevención & control , Parto Obstétrico , Femenino , Edad Gestacional , Humanos , Recién Nacido , Pandemias/prevención & control , Neumonía Viral/diagnóstico , Neumonía Viral/fisiopatología , Neumonía Viral/prevención & control , Embarazo , Complicaciones Infecciosas del Embarazo/diagnóstico , Complicaciones Infecciosas del Embarazo/fisiopatología
18.
Breastfeed Med ; 15(8): 492-494, 2020 08.
Artículo en Inglés | MEDLINE | ID: mdl-32644841

RESUMEN

Aim: The objective of our study was to determine whether the SARS-CoV-2-positive mothers transmit the virus to their hand-expressed colostrum. Methods: This is an observational prospective study that included pregnant women who tested positive for SARS-CoV-2 by PCR test on a nasopharyngeal swab at the moment of childbirth and who wanted to breastfeed their newborns. A colostrum sample was obtained from the mothers by manual self-extraction. To collect the samples, the mothers wore surgical masks, washed their hands with an 85% alcohol-based gel, and washed their breast with gauze that was saturated with soap and water. Results: We obtained seven colostrum samples from different mothers in the first hours postdelivery. SARS-CoV-2 was not detected in any of the colostrum samples obtained in our study. Conclusion: In our study, breast milk was not a source of SARS-CoV-2 transmission. Hand expression (assuring that a mask is used and that appropriate hygienic measures are used for the hands and the breast), when direct breastfeeding is not possible, appears to be a safe way of feeding newborns of mothers with COVID-19.


Asunto(s)
Betacoronavirus/aislamiento & purificación , Lactancia Materna/métodos , Extracción de Leche Materna/métodos , Calostro/virología , Infecciones por Coronavirus , Leche Humana/virología , Pandemias , Neumonía Viral , Complicaciones Infecciosas del Embarazo , Adulto , Técnicas de Laboratorio Clínico/métodos , Control de Enfermedades Transmisibles/métodos , Control de Enfermedades Transmisibles/normas , Infecciones por Coronavirus/diagnóstico , Infecciones por Coronavirus/epidemiología , Infecciones por Coronavirus/transmisión , Femenino , Humanos , Recién Nacido , Transmisión Vertical de Enfermedad Infecciosa/prevención & control , Masculino , Tamizaje Neonatal/métodos , Neumonía Viral/diagnóstico , Neumonía Viral/epidemiología , Neumonía Viral/transmisión , Embarazo , Complicaciones Infecciosas del Embarazo/diagnóstico , Complicaciones Infecciosas del Embarazo/epidemiología , España/epidemiología
19.
BMC Infect Dis ; 20(1): 528, 2020 Jul 22.
Artículo en Inglés | MEDLINE | ID: mdl-32698884

RESUMEN

BACKGROUND: Hepatitis B virus (HBV) infection is one of the major public health problems worldwide. Limited information exists about the epidemiology of HBV infection in Ethiopia. This study aimed to assess sero-prevalence of HBV markers and associated factors in children living in Hawassa City, southern Ethiopia. METHODS: A community-based cross-sectional study was conducted among 471 children in Hawassa City, southern Ethiopia from May to September, 2018. A total of 471 children were included in the study using a multistage sampling technique. Data on demographic and risk factors were gathered using structured questionnaires. Blood samples were collected and sera were screened for hepatitis B surface antigen (HBsAg), antibody to core antigen (anti-HBc), and antibody against surface antigen (anti-HBs) using enzyme-linked immunosorbent assay. RESULTS: The sero-prevalence of HBsAg, anti-HBc, and anti-HBs markers among children were 4.4, 19.5 and 20.0%, respectively. Children at higher risk of having HBsAg marker were those who had a history of injectable medications (AOR 5.02, 95% CI: 1.14, 22.07), a family history of liver disease (AOR 6.37, 95% CI: 1.32, 30.74), a HBsAg seropositive mothers, (AOR 11.19, (95% CI: 3.15, 39.67), and had no vaccination history for HBV (AOR, 6.37, 95% CI: 1.32, 30.74). Children from families with low monthly income, who were home delivered, unvaccinated for HBV or with HBsAg seropositive mother had increased risk of having anti-HBc. CONCLUSIONS: The study findings showed an intermediate endemicity of HBV infection in the study setting. The observed rate of residual HBV infection with low rate of immunized children after HBV vaccination was high. Hence, introducing birth dose vaccine, safe injection practice and improving immunization coverage during pregnancy as part of the antenatal care package should be considered. Furthermore, governmental and non-governmental organizations should give attention on timely measures for the prevention of ongoing vertical transmission from mother to child as well as early horizontal transmission of HBV in Hawassa City, Ethiopia.


Asunto(s)
Virus de la Hepatitis B/inmunología , Hepatitis B/sangre , Hepatitis B/epidemiología , Complicaciones Infecciosas del Embarazo/epidemiología , Biomarcadores/sangre , Niño , Preescolar , Estudios Transversales , Etiopía/epidemiología , Femenino , Hepatitis B/prevención & control , Hepatitis B/transmisión , Anticuerpos contra la Hepatitis B/sangre , Antígenos de Superficie de la Hepatitis B/sangre , Vacunas contra Hepatitis B/administración & dosificación , Humanos , Transmisión Vertical de Enfermedad Infecciosa/prevención & control , Masculino , Embarazo , Complicaciones Infecciosas del Embarazo/sangre , Complicaciones Infecciosas del Embarazo/prevención & control , Complicaciones Infecciosas del Embarazo/virología , Atención Prenatal/métodos , Prevalencia , Factores de Riesgo , Encuestas y Cuestionarios , Vacunación/métodos
20.
Midwifery ; 88: 102779, 2020 09.
Artículo en Inglés | MEDLINE | ID: mdl-32600862
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