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1.
Arthroscopy ; 33(5): 1007-1013, 2017 May.
Article En | MEDLINE | ID: mdl-28082062

PURPOSE: To compare the outcomes of 2 groups of patients undergoing anterior cruciate ligament (ACL) reconstruction: the first with a quadrupled semitendinosus gracilis (ST-G) autograft larger than 8 mm diameter and the second with a 5-strand ST-G autograft larger than 8 mm due to an insufficient diameter graft harvesting. METHODS: This was a retrospective study with 70 patients divided into 2 groups. Inclusion criteria included ACL ruptures of less than 3 months, ST-G ACL reconstructions, and final (4-strand or 5-strand) graft size larger than 8 mm. Exclusion criteria included multiligament knee injuries, meniscal or chondral pathology, ACL re-ruptures, inflammatory joint disease, or other procedures in the knee. RESULTS: Group A comprised 33 patients with a quadruple ST-G graft, and group B comprised 37 patients with an insufficient graft diameter (<8 mm) in which a 5-strand graft was used. Mean age in group A was 29.7 (range 17-52) years and in group B was 30.6 (range 13-53) years (P = .78). Average follow-up in group A was 32.2 (range 24-48) months and in group B was 30.35 (range 24-48) months (P = .75). Average graft diameter in group A was 8.5 mm (range 8-10) and in group B when the graft was measured as quadruple was 7.2 mm (range 6.5-7.5) and 9.2 mm (range 8-10) when it was converted to 5-strand (P = .00596). Group A had 3 (9%) re-ruptures, and group B had 2 (5.4%) (P = .55). The average postoperative Lysholm score in group A was 93.3 (range 71-100) and in group B was 97.1 (range 80-100) (P = .79). Mean postoperative International Knee Documentation Committee in group A was 91 (range 75.9-100) and in group B was 96.8 (range 82-100) (P = .18). CONCLUSIONS: In our study, the 5-strand hamstring autograft in ACL reconstruction was clinically comparable with the quadruple autograft larger than 8 mm. The differences in re-rupture and clinical outcomes were not statistically significant between the 2 groups, suggesting that it is a valid option when we have a graft of insufficient diameter. LEVEL OF EVIDENCE: Level III, retrospective comparative study.


Anterior Cruciate Ligament Injuries/surgery , Anterior Cruciate Ligament Reconstruction/methods , Autografts/anatomy & histology , Tendons/transplantation , Adolescent , Adult , Anterior Cruciate Ligament/surgery , Female , Follow-Up Studies , Humans , Knee Injuries/surgery , Knee Joint/surgery , Male , Middle Aged , Retrospective Studies , Tendons/anatomy & histology , Transplantation, Autologous/methods , Treatment Outcome , Young Adult
2.
Knee ; 23(6): 1098-1105, 2016 Dec.
Article En | MEDLINE | ID: mdl-27816290

BACKGROUND: The main option to perform an anatomic anterior cruciate ligament (ACL) reconstruction is the anteromedial portal (AMP) technique. It has several reported complications (iatrogenic chondral injury, posterior-wall blowout, short sockets, increased risk of injury to common peroneal nerve). In an attempt to avoid these complications the outside-in (OI) technique was revived with the addition of a retrodrill. The aim of this study is to evaluate the clinical and arthrometric outcomes of a series of anatomical OI single bundle ACL reconstruction using a retrodrill. METHODS: Prospective case series. KT-1000 and Pivot Shift Test were done at 24 months follow-up. International Knee Documentation Committee (IKDC), Lysholm and Tegner activity scores preoperatively and at final follow-up. Complications were reported. Statistical analysis was done with t-test. RESULTS: 275 knees of 200 (73%) males and 75 (27%) females were enrolled in the study. Mean age 29.1 years (15-54). Mean follow-up 34.5 months (24-49). Mean preoperatively Lysholm Score 62 (25-95) versus 95 (76-100) at final follow-up (p<0.001) Mean preoperatively IKDC score 60 (26.4-90.8) versus 92 (59.8-100) at final follow-up (p<0.001) Mean Tegner activity Score pre injury 5 versus 5 at final follow-up. (p=0.59) Mean KT-1000 side-to-side difference 2mm (1-6). Pivot Shift test negative in 243 patients (90%); positive in 32 (10%) patients. 13 (5%) ACL re-ruptures. 2 (0.7%) infections. No other complications were reported. CONCLUSION: OI single bundle anatomic ACL reconstruction using a retrodrill is a valid and safe option that avoids the complications reported with the AMP technique.


Anterior Cruciate Ligament Injuries/surgery , Anterior Cruciate Ligament Reconstruction/instrumentation , Arthroscopy/instrumentation , Adolescent , Adult , Anterior Cruciate Ligament Reconstruction/methods , Arthrometry, Articular , Arthroscopy/methods , Cohort Studies , Female , Humans , Knee Joint/physiopathology , Male , Middle Aged , Range of Motion, Articular , Recovery of Function , Treatment Outcome , Young Adult
3.
Artrosc. (B. Aires) ; 22(3): 71-77, sept.2015.
Article Es | LILACS, BINACIS | ID: lil-767404

Una década atrás la técnica transtibial para reconstrucción de LCA era la más popular y utilizada entre los cirujanos artroscopistas. A pesar de los buenos resultados la presencia de inestabilidad rotacional y el desarrollo de artrosis, han seguido siendo un foco de preocupación. Buscando respuestas se ha sugerido que el posicionamiento anatómico de los túneles sería una posible estrategia para reducir la inestabilidad rotacional y por tanto la artrosis futura. El propósito de este estudio es realizar una revisión de la literatura de alta calidad de los últimos 5 años sobre las distintas técnicas de reconstrucción “anatómicas” de LCA enfocándonos en los resultados clínicos de estas, y además exponer nuestra experiencia. Materiales y Método: Búsqueda en la base de datos PubMed. Se incluyeron estudios que se centraran específicamente en los resultados clínicos y artrométricos. Resultados: La búsqueda original produjo 389 resultados. Se eliminaron los que no cumplían los criterios de inclusión-exclusión quedando 10 estudios para revisión los cuales fueron divididos en: 1 revisión sistemática o metanálisis (nivel I), 5 estudios prospectivos randomizados (nivel I) y 4 estudios de cohorte prospectivos (nivel II). Conclusión: Las técnicas anatómicas de reconstrucción del LCA permiten restaurar de forma más adecuada la anatomía normal del LCA. Sin embargo esto aún no se ha visto reflejado en resultados clínicos mejores respecto a la técnica transtibial. El efecto protector en relación al desarrollo de artrosis futura también está en discusión. Por esto ambas técnicas siguen siendo una opción válida para ofrecer a nuestros pacientes. Nivel de Evidencia: V. Tipo de estudio: Revisión Bibliográfica...


Introduction: A decade ago the transtibial technique for ACL reconstruction was the most popular technique. Despite the good results there is concern regarding rotational stability and osteoarthritis. Looking for answers it has been suggested that anatomic ACL reconstruction could reduce these complications. The main objective of this study is to review high level evidence of the last 5 years regarding anatomic ACL reconstruction. Methods: Search in PubMed database. We included studies that focused on clinical results in anatomic ACL reconstruction. Results: 389 results. All the studies that not filled the inclusion-exclusion criteria were eliminated. 10 studies remained for revision: 1 systematic review/metanalysis (level I), 5 prospective randomized studies (level I) y 4 prospective cohort studies (level II). Conclusion: Anatomic ACL reconstruction techniques allows restoration of the normal anatomy of the ACL. However this does not improved clinical results compared to the transtibial technique. Finally both techniques are valid options to offer to our patients. Level of evidence: V. Type study: Review...


Humans , Arthroscopy/methods , Anterior Cruciate Ligament/surgery , Minimally Invasive Surgical Procedures , Anterior Cruciate Ligament Reconstruction
4.
Rev. cuba. oftalmol ; 28(2): 234-239, abr.-jun. 2015. ilus
Article Es | LILACS | ID: lil-761029

El síndrome de Chandler es una de las variaciones clínicas del síndrome iridocorneoendotelial, donde el denominador común es una alteración del endotelio corneal cuyo diagnóstico es, en ocasiones, muy difícil de realizar por la complejidad y la variabilidad de sus signos y síntomas. Se presenta una paciente de 67 años con disminución importante de la visión del ojo izquierdo. A la exploración existía un edema corneal severo, una midriasis pupilar, una corectopia leve hacia el sector temporal con tracción iridiana hacia el ángulo y sinequias anteriores angulares en el lado de la corectopia. La realización de un recuento endotelial demostró alteraciones cuali y cuantitativas del endotelio en el ojo izquierdo. Se concluyó que la microscopia especular es fundamental para el diagnóstico y la evaluación en casos sospechosos de síndrome de Chandler(AU)


Chandler's syndrome is a clinical variant of the iridocorneal endothelial syndrome in which the common aspect is the altered corneal endothelium that is sometimes very difficult to be diagnosed on account of the complexity and variability of signs and symptoms. This article was aimed at showing the effectiveness of specular microscopy for diagnosis. Here is a 67 years-old female patient who had significant reduction of vision in her left eye. On examination, there were observed severe corneal edema, pupillary mydriasis, mild corectopia towards the temporal sector with angled iridal traction and anterior angle synechias on the corectopia side. The endothelial counting revealed qualitative and quantitative alterations in the left eye. It was concluded that the specular microscopy is the key to diagnosis and assessment of suspected Chandler's syndrome cases(AU)


Humans , Female , Aged , Corneal Edema/diagnosis , Endothelium, Corneal/abnormalities , Gonioscopy/statistics & numerical data , Microscopy/statistics & numerical data , Mydriasis/diagnosis
5.
Rev. cuba. oftalmol ; 28(2): 234-239, abr.-jun. 2015. ilus
Article Es | CUMED | ID: cum-63867

El síndrome de Chandler es una de las variaciones clínicas del síndrome iridocorneoendotelial, donde el denominador común es una alteración del endotelio corneal cuyo diagnóstico es, en ocasiones, muy difícil de realizar por la complejidad y la variabilidad de sus signos y síntomas. Se presenta una paciente de 67 años con disminución importante de la visión del ojo izquierdo. A la exploración existía un edema corneal severo, una midriasis pupilar, una corectopia leve hacia el sector temporal con tracción iridiana hacia el ángulo y sinequias anteriores angulares en el lado de la corectopia. La realización de un recuento endotelial demostró alteraciones cuali y cuantitativas del endotelio en el ojo izquierdo. Se concluyó que la microscopia especular es fundamental para el diagnóstico y la evaluación en casos sospechosos de síndrome de Chandler(AU)


Chandler's syndrome is a clinical variant of the iridocorneal endothelial syndrome in which the common aspect is the altered corneal endothelium that is sometimes very difficult to be diagnosed on account of the complexity and variability of signs and symptoms. This article was aimed at showing the effectiveness of specular microscopy for diagnosis. Here is a 67 years-old female patient who had significant reduction of vision in her left eye. On examination, there were observed severe corneal edema, pupillary mydriasis, mild corectopia towards the temporal sector with angled iridal traction and anterior angle synechias on the corectopia side. The endothelial counting revealed qualitative and quantitative alterations in the left eye. It was concluded that the specular microscopy is the key to diagnosis and assessment of suspected Chandler's syndrome cases(AU)


Humans , Female , Aged , Endothelium, Corneal/abnormalities , Corneal Edema/diagnosis , Microscopy , Mydriasis/diagnosis , Gonioscopy
6.
Cancer Causes Control ; 24(6): 1223-30, 2013 Jun.
Article En | MEDLINE | ID: mdl-23553611

PURPOSE: Accurate identification of tobacco use is critical to implement evidence-based cessation treatments in cancer patients. The purpose of this study is to evaluate the accuracy of self-reported tobacco use in newly diagnosed cancer patients. METHODS: Tobacco use questionnaires and blood samples were collected from 233 newly diagnosed cancer patients (77 lung, 77 breast, and 79 prostate cancer). Blood was analyzed for cotinine levels using a commercially available enzyme-linked immunosorbent assay. Patients with cotinine measurements exceeding 10 ng/mL were categorized as current smokers. Smoking status based upon cotinine levels was contrasted with self-report in current smokers, recent quitters (1 or less year since quit), non-recent quitters (>1 year since quit), and never smokers. Multivariate analyses were used to identify potential predictors of discordance between self-reported and biochemically confirmed smoking. RESULTS: Cotinine confirmed 100 % accuracy in self-reporting of current and never smokers. Discordance in cotinine and smoking status was observed in 26 patients (15.0 %) reporting former tobacco use. Discordance in self-reported smoking was 12 times higher in recent (35.4 %) as compared with non-recent quitters (2.8 %). Combining disease site, pack-year history, and employment status predicted misrepresentation of tobacco use in 82.4 % of recent quitters. CONCLUSIONS: Self-reported tobacco use may not accurately assess smoking status in newly diagnosed cancer patients. Patients who claim to have recently stopped smoking within the year prior to a cancer diagnosis and lung cancer patients may have a higher propensity to misrepresent tobacco use and may benefit from biochemical confirmation.


Neoplasms/epidemiology , Self Report , Tobacco Use/blood , Adult , Aged , Aged, 80 and over , Cotinine/blood , Female , Humans , Male , Middle Aged , Neoplasms/blood , Risk Factors , Tobacco Use/epidemiology , United States/epidemiology
7.
Biophys J ; 95(2): 682-90, 2008 Jul.
Article En | MEDLINE | ID: mdl-18390623

Wide angle x-ray scattering (WAXS) from oriented lipid multilayers is used to examine liquid-ordered (Lo)/liquid-disordered (Ld) phase coexistence in the system 1,2-dioleoyl-sn-glycero-3-phosphocholine/1,2-dipalmitoyl-sn-glycero-3-phosphocholine/cholesterol (DOPC/DPPC/Chol), which is a model for the outer leaflet of the animal cell plasma membrane. Using the method of analysis developed in the accompanying work, we find that two orientational distributions are necessary to fit the WAXS data at lower temperatures, whereas only one distribution is needed at temperatures higher than the miscibility transition temperature, T(mix) = 25-35 degrees C (for 1:1 DOPC/DPPC with 15%, 20%, 25%, and 30% Chol). We propose that the necessity for two distributions is a criterion for coexistence of Lo domains with a high S(x-ray) order parameter and Ld domains with a lower order parameter. This criterion is capable of detecting coexistence of small domains or rafts that the conventional x-ray criterion of two lamellar D spacings may not. Our T(mix) values tend to be slightly larger than published NMR results and microscopy results when the fluorescence probe artifact is considered. This is consistent with the sensitivity of WAXS to very short time and length scales, which makes it more capable of detecting small, short-lived domains that are likely close to T(mix).


Cholesterol/chemistry , Lipid Bilayers/chemistry , Membrane Microdomains/chemistry , Phospholipids/chemistry , Molecular Conformation , Solutions , X-Ray Diffraction
8.
Rev. serv. sanid. fuerzas polic ; 48(1): 54-64, ene.-jun. 1987. tab
Article Es | LILACS, LIPECS | ID: lil-83077

El Hospital Central de las Fuerzas Policiales soporta una creciente demanda de atención por urgencias en sus servicios de Emergencia. Entre los años 1979 a 1982 el incremento fue de 19% anual, siendo el 12% de esas urgencias generadas pos accidentes y violencias. Se presenta un estudio prospectivo que demustra que en 1983 ingresaron a Emergencia 43748 pacientes, de los cuales 679 (1.5%) lo hicieron por lesiones producidas por accidentes y violencias, entre éstos el 58% fueron causadas por proyectiles de arma de fuego y artefactos explosivos; el 70% del total de heridos era personal policial en actividad, el cual había adquirido las lesiones con ocasión del servicio en un 78% de los casos, siendo el 70% causados por armas de fuego. Tales lesiones fueron en un 83% heteroinfringidas, manifestación del gran incremento de violencias que sufre el personal policial, lo que evidencia el alto riesgo que representa el desempeño de su actividad. Se propone el incio de un estudio epidemiológico relativo a los efectos que produce la violencia sobre la salud y la vida humana


Humans , Adult , Middle Aged , Male , Female , Wounds and Injuries/epidemiology , Accidents
9.
Rev. serv. sanid. fuerzas polic ; 46(1): 87-92, ene.-jun. 1985. tab
Article Es | LILACS, LIPECS | ID: lil-3533

Se evalúan 46,075 atenciones de urgencia realizadas durante los meses de Junio de 1983 y Mayo de 1984 en los Servicios de Emergencia del Hospital Central de Sanidad de las Fuerzas Policiales, de las cuales 4,497 (9.7%), fueron hechas a personas mayores de 60 años en las que predominaron las del sexo masculino. Se exponen estudios por grupos nosográficos y meses del año, analizándose incidencias y perfiles. La patología cardiovascular generó la mayor demanda de atención, 20.6%, siendo seguida por la nosografía digestiva, neurológica, respiratoria y traumatológica, las mismas que generaron la mayor mortalidad y exigencia de hospitalización


Middle Aged , Humans , Male , Female , Aged , Emergencies , Emergency Service, Hospital/standards , Health Services for the Aged/standards , Peru
10.
Rev. serv. sanid. fuerzas polic ; 45(2): 133-9, jul.-dic. 1984. tab
Article Es | LILACS | ID: lil-34818

Se han revisado 132,900 pacientes atendidos durante los años 1980 a 1982 en la División de Emergencia del Hospital Central de Sanidad de las Fuerzas Policiales. El 112% de la demanda correspondió a urgencias por lesiones con predominio de 3 a 1 en varones, los que, en 50% de casos, fueron personal policial en actividad. Las extremidades fueron el segmento más comprometido pero las lesiones de cabeza y tórax reunieron la mayor peligrosidad especialmente los producidos por proyectiles y por accidente de tránsito. La contusión fué el tipo de daño más frecuente observándose una mortalidad creciente por lesiones por arma de fuego incluyendo artefactos explosivos


Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Humans , Male , Female , Emergencies , Wounds and Injuries/epidemiology , Peru , Violence , Accidents
11.
Rev. serv. sanid. fuerzas polic ; 44(2): 185-98, 1983. tab
Article Es | LILACS | ID: lil-132658

Los desastres naturales han jugado un rol protagónico en la historia del Perú, siendo la costa- donde radican grandes asentamientos humanos- la que ha sufrido las mayores destrucciones por terremotos, lluvias torrenciales y efectos de aluviones. La catástrofe compromete la salud humana en modo y extensión variables exigiéndose a los hospitales esfuerzos desacostumbrados para atender la súbita demanda, hecho que implica eficientes niveles de organización e implementación de recursos y un alto grado de preparación de su personal. Se presenta, para evaluación, un proyecto de Manual que norma los Procedimientos Operativos del Hospital en casos de desastre, fase inicial e indispensable en la organización nosocomial para atender este tipo de daños


Peru , Disaster Planning/organization & administration , Hospital Planning/organization & administration
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