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1.
Wiad Lek ; 77(6): 1127-1133, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-39106370

RESUMEN

OBJECTIVE: Aim: To improve the management of morbidly obese patients who undergo gastric bypass surgery to reduce the number of postoperative complications, in particular, bleeding. PATIENTS AND METHODS: Materials and Methods: From 2011 to 2022, a total of 348 patients with morbid obesity (MO) underwent laparoscopic gastric bypass treatment at the clinical base of the Department of General Surgery №2 of Bogomolets National Medical University. The retrospective group included 178 patients who received treatment between 2011 and 2019. 170 patients were enrolled in the prospective group for the period from 2019 to 2022. RESULTS: Results: Retrospective group had 8 episodes of postoperative bleeding, representing a rate of 4.49%, prospective group - 3 episodes of postoperative bleeding, representing a rate of 1.76% Four factor characteristics associated with the probability of bleeding were identified: "number of comorbid conditions", "arterial hypertension", "chronic liver diseases" and "chronic obstructive pulmonary disease". CONCLUSION: Conclusions: The factors responsible for the occurrence of postoperative bleeding in morbidly obese patients after laparoscopic gastric bypass surgery were the number of comorbid conditions, the presence of arterial hypertension, the presence of chronic liver diseases, and chronic obstructive pulmonary disease. A new strategy for the management of morbidly obese patients after laparoscopic gastric bypass was developed. This strategy involves changing cassettes to create gastroentero- and enteroenteroanastomoses, reducing the period of use of the nasogastric tube, drains, and urinary catheter from 3-4 days to 1 day, and resuming the drinking regimen 6 hours after extubation.


Asunto(s)
Derivación Gástrica , Obesidad Mórbida , Hemorragia Posoperatoria , Humanos , Obesidad Mórbida/cirugía , Obesidad Mórbida/complicaciones , Derivación Gástrica/efectos adversos , Masculino , Femenino , Adulto , Estudios Retrospectivos , Hemorragia Posoperatoria/epidemiología , Hemorragia Posoperatoria/etiología , Persona de Mediana Edad , Laparoscopía/efectos adversos , Estudios Prospectivos
2.
Rev Med Liege ; 79(7-8): 489-491, 2024 Jul.
Artículo en Francés | MEDLINE | ID: mdl-39129545

RESUMEN

Duodenal ulcer perforation in patients undergoing gastric bypass surgery is a rare late complication, occurring in less than 1% of cases. It carries a high mortality risk, particularly in cases of delayed diagnosis. The challenge lies in an unspecific clinical presentation and laboratory findings, as well as a CT scan not very helpful in almost half of cases. These features may lead to the consideration of other differential diagnoses, such as pancreatitis or cholecystitis. A multidisciplinary approach in collaboration with digestive surgeons is essential to enable rapid exploratory laparoscopy in presence of diagnostic uncertainty, and appropriate therapeutic management.


La perforation de l'ulcère duodénal chez un patient ayant subi une chirurgie de bypass gastrique est une complication tardive rare, survenant dans moins de 1 % des cas. Elle présente un risque élevé de mortalité, particulièrement en cas de diagnostic retardé. Le défi réside dans une présentation clinique et des résultats biologiques peu spécifiques, ainsi qu'un scanner peu contributif dans près de la moitié des cas. Ces caractéristiques peuvent conduire à envisager d'autres diagnostics différentiels, tels que la pancréatite ou la cholécystite. Il est essentiel d'adopter une approche multidisciplinaire en collaboration avec les chirurgiens digestifs pour permettre une laparoscopie exploratrice rapide en cas d'incertitude diagnostique, ainsi qu'une prise en charge thérapeutique appropriée.


Asunto(s)
Úlcera Duodenal , Derivación Gástrica , Úlcera Péptica Perforada , Humanos , Derivación Gástrica/efectos adversos , Úlcera Péptica Perforada/cirugía , Úlcera Péptica Perforada/diagnóstico , Úlcera Duodenal/complicaciones , Úlcera Duodenal/cirugía , Femenino , Persona de Mediana Edad
3.
Medicine (Baltimore) ; 103(32): e39242, 2024 Aug 09.
Artículo en Inglés | MEDLINE | ID: mdl-39121271

RESUMEN

Avoidable readmissions after bariatric surgery are a major burden on the healthcare systems. Rates of readmission after bariatric surgery have ranged from 1% up to 20%, but the factors that predict readmission have not been well studied. The objective of this study was to determine readmission rates following bariatric surgery and identify factors that contribute to early (within 90 days of surgery) and late readmission. A retrospective cohort study of 736 patients undergoing either Laparoscopic Sleeve Gastrectomy or Laparoscopic Roux-en-Y Gastric Bypass in Jordan University Hospital from 2016 to 2019. Demographic characteristics, co-morbidities, and readmissions were extracted from their medical records and analyzed. Multivariable logistic regression analysis was performed to determine which factors predict readmission. A total of 736 patients had bariatric surgery (Laparoscopic Sleeve Gastrectomy 89% vs Laparoscopic Roux-en-Y Gastric Bypass 11%) during the study period. Thirty-day readmission rate was 6.62% and an overall readmission rate of 23.23%. Common reasons for early readmission (within 90 days of surgery) were nausea, vomiting, and dehydration. Late readmissions were mainly caused by gallbladder stones. Three risk factors were identified that independently predicted readmission: the type of procedure being performed (P-value = .003, odds ratio [OR] 2.14, 95% confidence interval [CI] 1.32-3.49), depression (P-value = .028, OR 6.49, 95% CI 1.18-52.9) and preoperative body mass index (P-value = .011, OR 1.03, 95% CI 1.01-1.05). Several factors were identified that cause patients to represent and subsequently admitted into hospitals. Early readmission was usually due to nausea, vomiting, and dehydration, whereas late admissions were mostly due to biliary complications. Preoperative body mass index and depression were independent risk factors for readmission.


Asunto(s)
Cirugía Bariátrica , Readmisión del Paciente , Complicaciones Posoperatorias , Humanos , Readmisión del Paciente/estadística & datos numéricos , Femenino , Masculino , Estudios Retrospectivos , Adulto , Factores de Riesgo , Persona de Mediana Edad , Jordania/epidemiología , Complicaciones Posoperatorias/epidemiología , Complicaciones Posoperatorias/etiología , Cirugía Bariátrica/efectos adversos , Obesidad Mórbida/cirugía , Derivación Gástrica/efectos adversos , Derivación Gástrica/métodos , Gastrectomía/efectos adversos , Laparoscopía/efectos adversos , Deshidratación/epidemiología , Deshidratación/etiología
4.
Nutrients ; 16(15)2024 Aug 01.
Artículo en Inglés | MEDLINE | ID: mdl-39125396

RESUMEN

Metabolic bariatric surgery remains the most effective and durable treatment for severe obesity. Women of reproductive age represent the largest demographic group undergoing these procedures. Metabolic bariatric surgery can have both beneficial and adverse effects on pregnancy outcomes. One of the most common adverse effects is fetal growth restriction. To mitigate these adverse effects, it is crucial to explore lifestyle modifications aimed at promoting a healthy pregnancy. Modifiable factors during pregnancy after metabolic bariatric surgery include the amount of gestational weight gain. The aim of this comprehensive review is to provide an overview of what is known about gestational weight gain in pregnancy after bariatric metabolic surgery. This review is focused on the two most performed procedures: sleeve gastrectomy and Roux-en-Y gastric bypass.


Asunto(s)
Cirugía Bariátrica , Ganancia de Peso Gestacional , Obesidad Mórbida , Humanos , Embarazo , Femenino , Cirugía Bariátrica/efectos adversos , Obesidad Mórbida/cirugía , Obesidad Mórbida/metabolismo , Complicaciones del Embarazo/etiología , Resultado del Embarazo , Derivación Gástrica/efectos adversos , Gastrectomía/efectos adversos , Gastrectomía/métodos , Adulto
5.
Obes Res Clin Pract ; 18(3): 195-200, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38955573

RESUMEN

INTRODUCTION: Revisional bariatric surgery (RBS) for insufficient weight loss/weight regain or metabolic relapse is increasing worldwide. There is currently no large multinational, prospective data on 30-day morbidity and mortality of RBS. In this study, we aimed to evaluate the 30-day morbidity and mortality of RBS at participating centres. METHODS: An international steering group was formed to oversee the study. The steering group members invited bariatric surgeons worldwide to participate in this study. Ethical approval was obtained at the lead centre. Data were collected prospectively on all consecutive RBS patients operated between 15th May 2021 to 31st December 2021. Revisions for complications were excluded. RESULTS: A total of 65 global centres submitted data on 750 patients. Sleeve gastrectomy (n = 369, 49.2 %) was the most common primary surgery for which revision was performed. Revisional procedures performed included Roux-en-Y gastric bypass (RYGB) in 41.1 % (n = 308) patients, One anastomosis gastric bypass (OAGB) in 19.3 % (n = 145), Sleeve Gastrectomy (SG) in 16.7 % (n = 125) and other procedures in 22.9 % (n = 172) patients. Indications for revision included weight regain in 615(81.8 %) patients, inadequate weight loss in 127(16.9 %), inadequate diabetes control in 47(6.3 %) and diabetes relapse in 27(3.6 %). 30-day complications were seen in 80(10.7 %) patients. Forty-nine (6.5 %) complications were Clavien Dindo grade 3 or higher. Two patients (0.3 %) died within 30 days of RBS. CONCLUSION: RBS for insufficient weight loss/weight regain or metabolic relapse is associated with 10.7 % morbidity and 0.3 % mortality. Sleeve gastrectomy is the most common primary procedure to undergo revisional bariatric surgery, while Roux-en-Y gastric bypass is the most commonly performed revision.


Asunto(s)
Cirugía Bariátrica , Reoperación , Pérdida de Peso , Humanos , Femenino , Masculino , Reoperación/estadística & datos numéricos , Cirugía Bariátrica/métodos , Cirugía Bariátrica/mortalidad , Cirugía Bariátrica/efectos adversos , Persona de Mediana Edad , Adulto , Estudios Prospectivos , Complicaciones Posoperatorias/mortalidad , Complicaciones Posoperatorias/etiología , Complicaciones Posoperatorias/epidemiología , Obesidad Mórbida/cirugía , Obesidad Mórbida/mortalidad , Derivación Gástrica/métodos , Derivación Gástrica/mortalidad , Derivación Gástrica/efectos adversos , Gastrectomía/métodos , Gastrectomía/efectos adversos , Aumento de Peso , Morbilidad
6.
Obes Surg ; 34(8): 3012-3020, 2024 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-39037676

RESUMEN

BACKGROUND: The efficacy of postoperative tranexamic acid (TXA) administration in mitigating bleeding after primary laparoscopic Roux-en-Y gastric bypass (RYGB), a prevalent complication associated with significant morbidities and mortality, and the use of sequential laboratory parameter changes in bleeding screening and TXA impact tracking were investigated. METHODS: This retrospective analysis included RYGB patients (aged 18-65 years, with a body mass index of 35-50 kg/m2) over 5 years who were categorized into three groups by evolving treatment regimens: Group A (n = 42) received standard pre- and postoperative enoxaparin (30 mg) every 12 h; Group B (n = 160) received enoxaparin and postoperative TXA (250 mg every 6 h); and Group C (n = 73) received TXA alone. Postoperative bleeding-related adverse events, vital signs, and laboratory changes were compared. RESULTS: Postoperative hemorrhage occurred in 3.6% (10/275) of patients, with no significant intergroup differences. Patients who experienced bleeding had greater decreases in hemoglobin (∆Hb) (2.1 vs. 1.4; p = 0.003), greater ∆Hb > 2 (50% vs. 15%; p = 0.013), and greater use of staples than did those who did not experience bleeding (8 vs. 7; p = 0.001). The ∆Hb values were lower in Groups B (1.4) and C (1.3) than in Group A (1.7, p = 0.011). No significant difference was noted between Groups C and B. CONCLUSION: This study emphasizes the potential of TXA to mitigate postoperative bleeding after RYGB, with no added benefit from excluding enoxaparin. Monitoring patients with a ∆Hb > 2 mg/dl and increased stapler usage is crucial. Further research is needed to validate routine TXA use across different procedures.


Asunto(s)
Antifibrinolíticos , Derivación Gástrica , Laparoscopía , Obesidad Mórbida , Hemorragia Posoperatoria , Ácido Tranexámico , Humanos , Ácido Tranexámico/administración & dosificación , Ácido Tranexámico/uso terapéutico , Derivación Gástrica/efectos adversos , Derivación Gástrica/métodos , Femenino , Estudios Retrospectivos , Adulto , Masculino , Hemorragia Posoperatoria/prevención & control , Hemorragia Posoperatoria/epidemiología , Persona de Mediana Edad , Antifibrinolíticos/administración & dosificación , Antifibrinolíticos/uso terapéutico , Obesidad Mórbida/cirugía , Enoxaparina/administración & dosificación , Adulto Joven , Anciano , Resultado del Tratamiento , Adolescente
9.
Langenbecks Arch Surg ; 409(1): 221, 2024 Jul 18.
Artículo en Inglés | MEDLINE | ID: mdl-39023536

RESUMEN

INTRODUCTION: The Single Anastomosis Sleeve Ileal (SASI) bypass is a new bariatric surgery corresponding to an adaptation of the Santoro approach, consisting of a sleeve gastrectomy (SG) followed by loop gastroileostomy. Therefore, we aimed to systematically assess all the current literature on SASI bypass in terms of safety, weight loss, improvement in associated comorbidities, and complications. METHODS: Following the Preferred Reporting Items for Systematic Reviews and Meta- Analyses (PRISMA) recommendations, we conducted a systematic review and meta-analysis by searching three databases (PubMed, Scopus, and Web of Science). We performed a meta-analysis of risk ratios and mean differences to compare surgical approaches for excessive weight loss, improvement/remission in type 2 diabetes mellitus (T2DM), hypertension (HT), dyslipidemia (DL), obstructive sleep apnea (OSA), and complications. Heterogeneity was assessed using the I2 statistic. RESULTS: Eighteen studies were included in the qualitative analysis and four in the quantitative analysis, comparing SASI bypass with SG and One-Anastomosis Gastric Bypass (OAGB). A comparison between Roux-en-Y Gastric Bypass (RYGB) and SASI bypass could not be performed. Compared to SG, the SASI bypass was associated with improved weight loss (MD = 11.32; 95% confidence interval (95%CI) [7.89;14.76]; p < 0.0001), and improvement or remission in T2DM (RR = 1.35; 95%CI [1.07;1.69]; p = 0.011), DL (RR = 1.41; 95%CI [1.00;1.99]; p = 0.048) and OSA (RR = 1.50; 95%CI [1.01;2.22]; p = 0.042). No statistically significant differences in any of the assessed outcomes were observed when compared with OAGB. When compared to both SG and OAGB, the complication rate of SASI was similar. CONCLUSION: Although studies with longer follow-up periods are needed, this systematic review and meta-analysis showed that SASI bypass has a significant effect on weight loss and metabolic variables. Variations in outcomes between studies reinforce the need for standardization.


Asunto(s)
Pérdida de Peso , Humanos , Diabetes Mellitus Tipo 2/cirugía , Diabetes Mellitus Tipo 2/complicaciones , Obesidad Mórbida/cirugía , Resultado del Tratamiento , Cirugía Bariátrica/métodos , Cirugía Bariátrica/efectos adversos , Derivación Gástrica/métodos , Derivación Gástrica/efectos adversos , Gastrectomía/métodos , Gastrectomía/efectos adversos , Apnea Obstructiva del Sueño/cirugía , Comorbilidad , Íleon/cirugía
10.
S D Med ; 77(7): 320-323, 2024 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-39013188

RESUMEN

Gas embolization is a rare but potentially deadly complication of any laparoscopic surgery. There has only been one other report of gas emboli in patients undergoing bariatric surgery. We present a case of gas embolization in a young female patient undergoing Roux-en-Y gastric bypass. Onset of gas embolus was identified by a dramatic drop in End Tidal Carbon Dioxide (ETCO2) followed by drops in blood pressure, heart rate, and oxygen saturation over the following 15 minutes before the patient was stabilized and transferred to the ICU. The surgery was completed three days later without incident, and extensive hepatomegaly was identified. A discussion on pre-operative evaluation, special considerations, and acute management of gas embolization in patients with obesity ensues. We highlight the emerging Jain's point for insufflation, the potential for ultrasound-guided Verres needle insertion, and the paucity of literature evaluating the risk, incidence, and outcomes of gas embolization in patients with obesity.


Asunto(s)
Embolia Aérea , Derivación Gástrica , Humanos , Femenino , Embolia Aérea/etiología , Embolia Aérea/terapia , Derivación Gástrica/efectos adversos , Derivación Gástrica/métodos , Adulto , Dióxido de Carbono , Obesidad/complicaciones , Obesidad Mórbida/complicaciones
11.
Obes Surg ; 34(8): 2806-2813, 2024 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-38902480

RESUMEN

INTRODUCTION: Internal hernia (IH) after Roux-Y gastric bypass (RYGB) can lead to extended small bowel ischemia if it not recognized and treated promptly. The aim of this study is to show whether improvement in mesenteric defect (MD) closure reduces the incidence of IH. PATIENTS AND METHODS: Retrospective analysis of prospectively collected data from our database including all patients who underwent laparoscopic RYGB between 1999 and 2015. The usual technique was a retrocolic/retrogastric RYGB. We divided patients in four groups according to the closure technique for MD and compared incidences of IH between groups. All patients had at least 8 years of follow-up. RESULTS: A total of 1927 patients (1497 females/460 males, mean age of 41.5 ± 11 years) were operated. A retrocolic/retrogastric RYGB was performed in 1747 (90.7%) and an antecolic RYGB in 180 patients. Mean duration of follow-up was 15 (8-24) years. 111 patients (5.8%) developed IH, the majority through the jejunojejunostomy (JJ, 3.7%) and Petersen (1.7%) defects. With improvement of closure technique, the incidence decreased over time, from 12.9% in the group with separate sutures to 1.05% in the most recent group with running non-absorbable sutures and an additional purse-string at the JJ defect (p < 0.0001). CONCLUSION: Meticulous closure of MD during RYGB is a very important step that significantly reduces the IH risk after RYGB, even with a retrocolic/retrogastric anatomy. Using running non absorbable braided sutures and an additional purse-string suture at the JJ is the most effective technique, but a small IH risk persists. A high index of suspicion remains necessary in patients who present with acute abdominal pain after RYGB.


Asunto(s)
Derivación Gástrica , Hernia Interna , Laparoscopía , Mesenterio , Obesidad Mórbida , Humanos , Derivación Gástrica/efectos adversos , Derivación Gástrica/métodos , Femenino , Masculino , Adulto , Estudios Retrospectivos , Incidencia , Mesenterio/cirugía , Obesidad Mórbida/cirugía , Hernia Interna/etiología , Hernia Interna/prevención & control , Hernia Interna/epidemiología , Persona de Mediana Edad , Complicaciones Posoperatorias/epidemiología , Complicaciones Posoperatorias/prevención & control , Resultado del Tratamiento , Estudios de Seguimiento , Técnicas de Sutura
12.
Surg Endosc ; 38(8): 4496-4504, 2024 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-38914888

RESUMEN

BACKGROUND: Bariatric surgery has been proven to be the most effective therapy for obesity and Roux-en-Y gastric bypass (RYGB) is one of the most commonly performed procedure. However, weight regain and dumping syndrome occur over time. The transoral outlet reduction (TORe) procedure using an endoscopic suturing device may be an option to treat these conditions. We aimed to analyze outcome parameters and long-term results for this endoscopic technique. METHODS: A retrospective data analysis of patients who underwent TORe using an endoscopic suturing system at our institution from January 2015 to December 2020 was performed. A total of 71 subjects were included. Forty-five patients received the intervention for weight regain, 9 for dumping syndrome and 17 for both. The primary endpoint was weight stabilization or weight loss for subjects with weight regain, and resolution of symptoms for those with dumping syndrome. Secondary endpoints were intraoperative complications, procedure time, length of hospital stay and diameter of gastrojejunal anastomosis 1 year post-intervention. RESULTS: The median size of the gastrojejunal anastomosis was estimated at 30 mm before intervention, and after performing a median of 3 endoscopic sutures, the median estimated gastrojejunal anastomosis width was reduced to 9.5 mm. Eight perioperative complications occurred. Overall mean follow-up was 26.5 months. All interventions achieved weight stabilization or weight loss or resolution of dumping symptoms within the first 3 months, 98.2% at 12 months, 91.4% at 24 months and 75.0% at 48 months. In 22/26 subjects a persisting improvement of dumping syndrome was achieved. CONCLUSIONS: TORe is a safe and effective procedure in the treatment of patients with dumping syndrome after laparoscopic RYGB, the effect on weight stabilization is less significant. A prospective randomized trial should be conducted to compare the effects of TORe with other surgical methods like banding the gastrojejunal anastomosis.


Asunto(s)
Síndrome de Vaciamiento Rápido , Derivación Gástrica , Aumento de Peso , Humanos , Femenino , Masculino , Derivación Gástrica/métodos , Derivación Gástrica/efectos adversos , Estudios Retrospectivos , Persona de Mediana Edad , Síndrome de Vaciamiento Rápido/etiología , Adulto , Resultado del Tratamiento , Obesidad Mórbida/cirugía , Técnicas de Sutura , Estómago/cirugía , Pérdida de Peso , Yeyuno/cirugía
13.
Obes Surg ; 34(8): 2923-2929, 2024 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-38884901

RESUMEN

PURPOSE: The use of a nonadjustable silicone band around the gastric pouch of Roux-en-Y gastric bypass (RYGB) to reduce the recurrence of obesity is still being debated in the literature. The primary objective of this study was to evaluate banded and non-banded RYGB regarding % total weight loss (%TWL) and complications up to 10 years postoperatively and regarding the removal rate of the silicone band. MATERIAL AND METHODS: A retrospective study of the medical records of all patients submitted to banded and non-banded RYGB between 2000 and 2020 was conducted. Clinical data (age, gender, weight, body mass index-BMI, comorbidities, %TWL, and the prevalence of vomiting) and laboratory data (hemoglobin, serum iron, albumin, and vitamin B12) were obtained preoperatively and at 6 months, 1, 2, 3, 5, 7, and 10 years for both groups and at 12, 15, and 20 years after banded RYGB. RESULTS: In total, 858 patients underwent RYGB: 409 underwent banded RYGB and 449 underwent non-banded RYGB. In the preoperative period, banded RYGB patients were heavier and had higher rates of hypertension and dyslipidemia. The %TWL was higher in the banded RYGB group up to 7 years. The prevalence of vomiting is much higher in this group, which also had lower laboratory test values. Of the banded RYGB patients, 9.53% had to have the silicone ring removed after presenting complications. CONCLUSION: Banded RYGB promotes significantly higher rates of TWL at the expense of a higher frequency of food intolerance and vomiting.


Asunto(s)
Derivación Gástrica , Obesidad Mórbida , Complicaciones Posoperatorias , Pérdida de Peso , Humanos , Derivación Gástrica/efectos adversos , Estudios Retrospectivos , Femenino , Masculino , Obesidad Mórbida/cirugía , Adulto , Persona de Mediana Edad , Complicaciones Posoperatorias/epidemiología , Gastroplastia/métodos , Gastroplastia/efectos adversos , Resultado del Tratamiento , Índice de Masa Corporal
14.
Surg Endosc ; 38(8): 4680-4685, 2024 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-38886233

RESUMEN

BACKGROUND: Recently, endoscopic ultrasound-guided (EUS) gastrojejunostomy (GJ) has emerged as an alternative option to surgical palliation and endoscopic duodenal stenting for malignant gastric outlet obstruction (GOO). Although early success rates are commonly reported with the technique, there is a paucity of data regarding the long-term efficacy of this approach. In this study, we investigated long-term outcomes in patients that underwent EUS-guided GJ for palliation of periampullary malignancies. METHODS: From a total of 192 studies that were reviewed, 6 studies with a follow-up time frame of a minimum of 5 months were analyzed, totaling 238 patients. Outcome variables included technical success rate, clinical success rate, adverse events, symptom recurrence, and re-intervention rates. RESULTS: The cohort of 238 patients had a technical success rate of 93.7% and a clinical success rate of 92.9%. A total of 25 patients (10.5%) experienced adverse events associated with EUS-GJ. A total of 14 patients (5.9%) experienced recurrence of GOO symptoms within 5 months. A total of 14 patients (5.9%) underwent re-intervention with the first 5 months. CONCLUSIONS: This systematic review shows that data are scarce regarding long-term effectiveness of EUS-guided GJ. Even though early success rates have been reported, further studies are needed to focus on long-term efficacy of this approach. Until such studies become available, surgical palliation should continue to be the treatment of choice for patients with malignant GOO with a prolonged life expectancy.


Asunto(s)
Derivación Gástrica , Obstrucción de la Salida Gástrica , Obstrucción de la Salida Gástrica/cirugía , Obstrucción de la Salida Gástrica/etiología , Humanos , Derivación Gástrica/métodos , Derivación Gástrica/efectos adversos , Resultado del Tratamiento , Cuidados Paliativos/métodos , Endosonografía/métodos , Ampolla Hepatopancreática/cirugía , Neoplasias del Conducto Colédoco/cirugía , Neoplasias del Conducto Colédoco/complicaciones , Neoplasias Duodenales/cirugía , Neoplasias Duodenales/complicaciones
16.
Cir Cir ; 92(3): 395-398, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38862118

RESUMEN

A rare condition, sclerosing encapsulating peritonitis, is characterized by a fibrotic membrane forming over the bowels, leading to intestinal obstruction. In this case of a 56-year-old male patient with a history of laparoscopic gastric bypass, a computed tomography scan showed findings indicative of the condition. Extensive adhesiolysis was performed, and biopsies confirmed the presence of fusiform cells (D2-40 positive on immunochemistry) resembling fibroblasts, within dense collagenous peritoneal tissue sheets, typical of sclerosing encapsulating peritonitis. The prevalence of this condition is uncertain, and diagnosis typically requires a peritoneal biopsy due to the nonspecific clinical presentation.


La peritonitis esclerosante encapsulada es una condición rara caracterizada por una membrana fibrótica que se genera sobre las asas intestinales causando cuadros de oclusión intestinal. Se presenta el caso de un paciente varón de 56 años con antecedente de derivación gastroyeyunal por laparoscopia que presenta oclusión intestinal. Se realizó tomografía computada que evidenció sitio de transición previo al sitio de anastomosis. Se realizó de anastomosis extensa y toma de biopsias. Histológicamente se observó engrosamiento de la membrana peritoneal, células fusiformes (D2-40 positivo en inmunohistoquímica) similares a fibroblastos con láminas de colágeno peritoneal denso. La peritonitis esclerosante encapsulada es una patología de prevalencia desconocida. El cuadro clínico es inespecífico y el diagnóstico definitivo es por patología con biopsia peritoneal.


Asunto(s)
Derivación Gástrica , Obstrucción Intestinal , Fibrosis Peritoneal , Complicaciones Posoperatorias , Humanos , Masculino , Persona de Mediana Edad , Derivación Gástrica/efectos adversos , Obstrucción Intestinal/etiología , Obstrucción Intestinal/cirugía , Complicaciones Posoperatorias/etiología , Fibrosis Peritoneal/etiología , Fibrosis Peritoneal/cirugía , Fibrosis Peritoneal/complicaciones , Fibrosis Peritoneal/diagnóstico por imagen , Peritonitis/etiología , Síndrome , Adherencias Tisulares/complicaciones , Tomografía Computarizada por Rayos X , Intestino Delgado
17.
Cardiovasc Diabetol ; 23(1): 205, 2024 Jun 15.
Artículo en Inglés | MEDLINE | ID: mdl-38879559

RESUMEN

BACKGROUND: There has been a substantial increase in the use of laparoscopic sleeve gastrectomy (SG) to treat morbid obesity despite observational evidence demonstrating the superiority of Roux-en-Y gastric bypass (RYGB) for reducing low-density lipoprotein (LDL) cholesterol. The main aim was to ascertain whether high LDL cholesterol levels should be considered when selecting the most appropriate surgical procedure for each patient (RYGB or SG). METHODS: In this single-center, randomized clinical trial using intention-to-treat analysis, 38 patients with severe obesity and elevated levels of LDL cholesterol were randomly assigned to undergo RYGB or SG. The primary outcome was LDL cholesterol remission at 12 months, defined as LDL cholesterol < 3.36 nmol/l without lipid-lowering medications. Secondary outcomes included changes in weight, other comorbidities, qualitative lipoprotein traits, cholesterol esters, glycoproteins, cholesterol absorption and synthesis metabolites and complications. RESULTS: Intention-to-treat analysis revealed that LDL cholesterol remission occurred in 66.6% of RYGB patients compared to 27.8% of SG patients (p = 0.019). Among patients completing follow-up, RYGB demonstrated superior remission (80.0% vs. 29.4%, p = 0.005). Exclusive benefits of RYGB included a reduction in large, medium, and small LDL particles. Cholesterol absorption markers showed differential behavior after both techniques: campesterol (Δ -15.2 µg/mg, 95% CI -30.2 to -0.1) decreased after RYGB, and sitosterol (Δ 21.1 µg/mg, 95% CI 0.9 to 41.2), cholestanol (Δ 30.6 µg/mg, 95% CI 14.8 to 57.9) and campesterol (Δ 18.4 µg/mg, 95% CI 4.4 to 32.3) increased after SG. No differences in weight loss, cholesterol esters, glycoproteins, cholesterol synthesis metabolites or postoperative complications were observed between techniques. CONCLUSION: In conclusion, RYGB is superior to SG in terms of short-term of high LDL cholesterol remission. Furthermore, RYGB also led to a greater improvement in lipoprotein parameters that confer an atherogenic profile. Therefore, the presence of elevated levels of LDL cholesterol should be considered when determining the optimal bariatric surgery procedure for each patient. TRIAL REGISTRATION: Clinicaltrials.gov number, NCT03975478).


Asunto(s)
Biomarcadores , LDL-Colesterol , Gastrectomía , Derivación Gástrica , Obesidad Mórbida , Humanos , Masculino , Femenino , Derivación Gástrica/efectos adversos , Gastrectomía/efectos adversos , Adulto , Persona de Mediana Edad , LDL-Colesterol/sangre , Resultado del Tratamiento , Obesidad Mórbida/cirugía , Obesidad Mórbida/sangre , Obesidad Mórbida/diagnóstico , Factores de Tiempo , Biomarcadores/sangre , Pérdida de Peso , Inducción de Remisión , Laparoscopía/efectos adversos , Hipercolesterolemia/sangre , Hipercolesterolemia/diagnóstico , Hipercolesterolemia/tratamiento farmacológico , Sitoesteroles/sangre
18.
Langenbecks Arch Surg ; 409(1): 194, 2024 Jun 20.
Artículo en Inglés | MEDLINE | ID: mdl-38937299

RESUMEN

BACKGROUND: Weight loss failure after bariatric surgery imposes great stress on patients and surgeons and great costs on healthcare systems. The literature review shows that weight loss failure is the most common cause of redo bariatric surgery. Therefore, identifying the predictors of weight loss failure in patients in the early stages can help bariatric surgeons. The present study aims to determine the association between primary weight loss and long-term weight loss outcomes. METHODS: This retrospective cohort study was conducted on 329 patients undergoing OAGB who were followed for 60 months. For the prediction of short-term (24 months) and long-term (60 months) successful weight loss and weight regain, we used %TWL and BMI at any regular follow-ups. RESULTS: In preoperative indices, age, sex, DLP, hypothyroidism, and HTN were not significant to predict successful short-term and long-term weight loss but %TWL at 12 months is a significant predictor of successful weight loss in short-term and long-term follow up. In the prediction of weight regain, preoperative indices (except BMI) were not significant but 12-month %TWL was a significant predictor. CONCLUSIONS: This index can help surgeons find these patients early and provide helpful instructions to manage their issues more promptly to reach better weight loss outcomes.


Asunto(s)
Derivación Gástrica , Obesidad Mórbida , Pérdida de Peso , Humanos , Femenino , Masculino , Estudios Retrospectivos , Derivación Gástrica/efectos adversos , Adulto , Persona de Mediana Edad , Obesidad Mórbida/cirugía , Resultado del Tratamiento , Índice de Masa Corporal , Factores de Tiempo , Estudios de Cohortes , Anastomosis Quirúrgica
19.
Obes Surg ; 34(7): 2627-2633, 2024 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-38837020

RESUMEN

INTRODUCTION: Revisional bariatric surgery is associated with higher perioperative complications over primary procedures. Adjustable gastric bands (AGB) continue to be the most frequently converted bariatric configuration. This study examines trends in current clinical indication and safety profile of the most frequently pursued AGB conversions. MATERIALS AND METHODS: MBSAQIP data from 2020 to 2022 was retrospectively analyzed in a cohort study examining 30-day postoperative outcomes after AGB conversion to sleeve gastrectomy (SG), Roux-en-Y gastric bypass (RYGB), or single anastomosis duodenoileostomy (SADI). Descriptive statistics were used, including multivariable and 2:1 nearest neighbor matching analysis. RESULTS: This study included 19,335 AGB conversions, of which most were to SG (n = 11,736) followed by RYGB (n = 7442) and SADI (n = 157). While a majority were completed for weight loss, there were differences in distribution of primary indication for each conversion cohort, such as higher proportion of RYGB conversion for gastroesophageal reflux disease (18.7%) compared to SG (7.92%) and SADI (5.10%). Multivariable analysis demonstrates conversion to RYGB has significantly higher odds of 30-day major complications (OR 1.75, p < 0.001), reoperation (OR 2.08; p = 0.001), readmission (OR 1.69; p = 0.001), and emergency department visits (OR 1.50; p = 0.001) over SG. These risks and odds of reintervention (OR 1.75; p < 0.001) remained significantly higher after conversion to RYGB versus SG on matched analysis. None of these risks is significantly different between conversions to SADI versus SG in either multivariable or matched analysis. CONCLUSIONS: Compared to AGB conversion to SG, single-stage conversion to RYGB had increased odds of perioperative complications while risks of conversion to SADI were not significantly different.


Asunto(s)
Gastrectomía , Derivación Gástrica , Obesidad Mórbida , Complicaciones Posoperatorias , Reoperación , Humanos , Derivación Gástrica/métodos , Derivación Gástrica/efectos adversos , Femenino , Masculino , Estudios Retrospectivos , Gastrectomía/métodos , Obesidad Mórbida/cirugía , Reoperación/estadística & datos numéricos , Adulto , Persona de Mediana Edad , Complicaciones Posoperatorias/epidemiología , Gastroplastia/métodos , Gastroplastia/efectos adversos , Pérdida de Peso , Anastomosis Quirúrgica/métodos , Duodeno/cirugía , Resultado del Tratamiento
20.
Obes Surg ; 34(7): 2754, 2024 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-38837021

RESUMEN

Gastric bypass surgery is a common and effective procedure for obesity and associated comorbidities. However, long-term complications, such as internal hernias, can pose diagnostic and therapeutic challenges. Internal hernias after gastric bypass are rare but can lead to severe complications, including volvulus and bowel ischemia. Understanding the anatomical variations and employing laparoscopic techniques for resolution are crucial in managing these cases.


Asunto(s)
Derivación Gástrica , Hernia Interna , Laparoscopía , Obesidad Mórbida , Humanos , Laparoscopía/métodos , Hernia Interna/cirugía , Derivación Gástrica/efectos adversos , Derivación Gástrica/métodos , Femenino , Obesidad Mórbida/cirugía , Herniorrafia/métodos , Resultado del Tratamiento , Complicaciones Posoperatorias , Adulto
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