ABSTRACT
Rosai-Dorfman disease (RDD) is uncommon in daily practice, but needs to be ruled out in rheumatologic conditions to elucidate a wide differential diagnosis. Beside its typical presentation, soft tissue masses can be easily seen in our Rheumatology clinics. Ultrasonography widely extended in our specialty, could also play a role in the diagnosis, to end up with the histological confirmation of the disease
La enfermedad Rosai-Dorfman (ERD) es infrecuente en nuestra práctica diaria, aunque se debe considerar en el diagnóstico diferencial de diferentes procesos en reumatología. La presentación en forma de masa de partes blandas incluye el estudio radiológico y la ecografía de partes blandas muy extendida en nuestra especialidad y, finalmente, la confirmación histológica
Subject(s)
Humans , Female , Middle Aged , Histiocytosis, Sinus/diagnostic imaging , Histiocytosis, Sinus/pathology , Subcutaneous Tissue/pathology , Forearm/diagnostic imaging , Diagnosis, Differential , Forearm/pathology , Image-Guided Biopsy , Emperipolesis/immunologyABSTRACT
Rosai-Dorfman disease (RDD) is uncommon in daily practice, but needs to be ruled out in rheumatologic conditions to elucidate a wide differential diagnosis. Beside its typical presentation, soft tissue masses can be easily seen in our Rheumatology clinics. Ultrasonography widely extended in our specialty, could also play a role in the diagnosis, to end up with the histological confirmation of the disease.
Subject(s)
Histiocytosis, Sinus , Diagnosis, Differential , Female , Forearm/diagnostic imaging , Forearm/pathology , Histiocytosis, Sinus/diagnostic imaging , Histiocytosis, Sinus/pathology , Humans , Middle Aged , UltrasonographyABSTRACT
Advanced imaging has demonstrated that musculoskeletal manifestations of systemic sarcoidosis are more common than previously thought. A definitive strategy for the management of osseous sarcoidosis has not been defined. Some lesions resolve spontaneously, and no systemic medication for sarcoidosis consistently resolves lesions. The orthopaedic surgeon treating patients with musculoskeletal sarcoidosis must make an appropriate diagnosis of bony lesions, seek multidisciplinary input from specialists in pulmonology and rheumatology regarding systemic treatment, and decide when surgery is necessary to prevent dysfunction.
Subject(s)
Musculoskeletal Diseases/therapy , Orthopedic Procedures/methods , Orthopedics/methods , Sarcoidosis/therapy , Disease Management , Humans , Musculoskeletal Diseases/physiopathology , Patient Care Team , Sarcoidosis/physiopathologySubject(s)
Antibodies, Monoclonal, Humanized/adverse effects , Antibodies, Monoclonal/adverse effects , Arthritis/chemically induced , Chondrocalcinosis/chemically induced , Melanoma/drug therapy , Skin Neoplasms/drug therapy , Antibodies, Monoclonal/therapeutic use , Antibodies, Monoclonal, Humanized/therapeutic use , Arthritis/pathology , Chondrocalcinosis/pathology , Follow-Up Studies , Humans , Male , Melanoma/pathology , Middle Aged , Neoplasm Invasiveness/pathology , Neoplasm Staging , Risk Assessment , Skin Neoplasms/pathologyABSTRACT
No disponible
Subject(s)
Humans , Male , Female , Histiocytosis, Langerhans-Cell/classification , Biopsy , CD4 Immunoadhesins/analysis , Antigens, CD1/analysis , Diagnosis, DifferentialABSTRACT
The objectives of this study are to examine whether specific foot disorders and ankle weakness and foot pain are related to functional limitations or disabilities in elders. Community-dwelling adults 65 and older were enrolled in a population-based, cross-sectional study of foot disorders and health outcomes. Demographics, health status, comorbidities, self-reported foot and knee pain, function and disability, and observed structural foot disorders, body mass index, and ankle muscle strength were assessed on 717 participants. The associations of foot disorders, foot pain, and ankle muscle weakness with function and disability were examined with regression analyses. Foot disorders were not associated with functional outcomes or disability. Ankle weakness was associated with performance-based function (p = .005), self-report function (p lesser than .001), and disability (p = .009). Foot pain was associated with self-report function (p = .01) and disability (p = .007). Foot pain and ankle weakness seem to be related to important health outcomes among older adults.
Subject(s)
Activities of Daily Living , Aged , Disabled Persons , Foot Diseases/complications , Muscle Weakness/etiology , Ankle , Body Mass Index , Comorbidity , Health Status , Humans , Massachusetts , Pain/etiologyABSTRACT
OBJECTIVES: To examine whether common musculoskeletal disorders of feet are associated with pain and foot-related functional limitation. DESIGN: A cross-sectional study using stratified random sampling. SETTING: A residential community. PARTICIPANTS: Ethnically diverse sample of elderly persons (n=784). MEASUREMENTS: Foot disorders (hallux valgus/bunion, pes planus (flat foot), pes cavus (high arch), hammertoe, mallet toe, claw toe, overlapping toes, bunionette, and plantar fasciitis), foot pain, the foot health functional status (FHFS, range 0-100, 100=no problems) scale, and walk time score (range 0-4, 4=fastest). RESULTS: Most commonly assessed musculoskeletal disorders, including hallux valgus and toe deformities, were not associated with pain or function limitation. Plantar fasciitis and, to a lesser extent, pes cavus were associated with worse FHFS scores; foot pain partially explained this association. Neither foot disorders nor foot pain were significantly associated with slower walk times. CONCLUSION: Many foot disorders had little relationship with foot pain or function and may not require clinical attention when asymptomatic. Risk factors and preventive and therapeutic interventions for plantar fasciitis require further longitudinal investigation.
