ABSTRACT
The authors describe the surgical technique used to obtain (by anterior and posterior access) autoplastic bone from the ilium in 186 oncological cases. Indications, the results obtained and the principal causes of complications are discussed.
Subject(s)
Bone Transplantation/methods , Ilium/transplantation , Postoperative Complications/epidemiology , Bone Neoplasms/complications , Bone Neoplasms/surgery , Bone Transplantation/adverse effects , Humans , Postoperative Complications/etiology , Transplantation, AutologousABSTRACT
This report deals with endemic chronic arsenical intoxication (HACRE) observed in several provinces in Argentina. Similar reports come from Chili, Mexico, Brasil, Bolivia, Peru and Japan. HACRE patients show no systemic, symptoms and specific manifestations are palmoplantar keratoderma, multiple cutaneous epitheliomas, mainly Bowen-type and respiratory or digestive carcinomas. The authors emphasize that these specific manifestations of HACRE are worth knowing for their possible social incidence.
Subject(s)
Arsenic Poisoning , Keratoderma, Palmoplantar/chemically induced , Skin Neoplasms/chemically induced , Water Pollutants, Chemical/poisoning , Water Pollutants/poisoning , Adolescent , Adult , Aged , Argentina , Child , Child, Preschool , Diagnosis, Differential , Digestive System Neoplasms/chemically induced , Female , Humans , Infant , Infant, Newborn , Japan , Keratoderma, Palmoplantar/pathology , Latin America , Leukoplakia, Oral/chemically induced , Male , Middle Aged , Nervous System Diseases/chemically induced , Respiratory Tract Neoplasms/chemically induced , Skin Diseases/diagnosis , Skin Neoplasms/pathology , Space-Time ClusteringABSTRACT
From 1972 to October 1982 we have observed 39 cases of mycetoma in the Skin Department of the Hospital del Milagro, Salta (Argentina). The diagnosis was based on the clinical aspect, mycological studies and in most cases histopathology was done as well. The mayoritary of the patients were farmers. From the clinical point of view there si a true prevalence of Nocardia Brasiliensis. Most of the mycetomas can be found in the lower limbs. Some of the patients presented quite severe lesions and eight of them had bone involvement. The combination of long action sulphas with sulphonas has been efficient enough in the treatment of mycetomas caused by Nocardia Brasiliensis.
Subject(s)
Mycetoma/epidemiology , Nocardia Infections/epidemiology , Actinomycetaceae/isolation & purification , Adult , Aged , Argentina , Dapsone/therapeutic use , Drug Combinations/therapeutic use , Drug Therapy, Combination , Female , Humans , Male , Middle Aged , Mitosporic Fungi/isolation & purification , Mycetoma/drug therapy , Mycetoma/microbiology , Nocardia/isolation & purification , Nocardia Infections/drug therapy , Sulfamethoxazole/therapeutic use , Trimethoprim/therapeutic use , Trimethoprim, Sulfamethoxazole Drug CombinationABSTRACT
Arsenical pollution of water supplies is a chronic problem of great medical, social and sanitary importance in Argentina. The well-known cutaneous manifestations of chronic arsenical toxicity, palmar and plantar keratoses, melanoderma and multiple epitheliomas are described. The interest which this disease has evoked in the last few years is emphasized when new arsenical areas are discovered with clinical cases of chronic arsenical intoxication. Furthermore it is shown that the high content of arsenic in drinking water may be the determining factor in the incidence of visceral neoplasms. Contrary to classic beliefs, the chronic toxic effects from arsenic may be present in young children but the palmar and plantar keratoses may be absent. The histochemical localization of the arsenic in the skin and its relation to thyroid function and the production of leukoplakia and laryngeal cancer are noted. When one analyses all the recent reports it is evident that patients with chronic arsenical intoxication must now be thoroughly studied bearing in mind the multiple localization of this carcinogenic agent.