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G Ital Nefrol ; 41(3)2024 06 28.
Article in Italian | MEDLINE | ID: mdl-38943326

ABSTRACT

Cystic fibrosis is a multisystem disease with extremely variable onset, symptoms and course. One of the onset modality but also a complication of the disease is the pseudo-Bartter syndrome, characterized by hyponatremia, hypochloremic dehydration and metabolic alkalosis in absence of any renal disease. This syndrome occurs more frequently in the first year of life and has a peak in the summer. In this article, we describe two cases of cystic fibrosis associated with pseudo-Bartter syndrome in childhood. Excluding every possible cause of metabolic alkalosis associated with hyponatremia was crucial for our diagnostic pathway, and the experience gained with the first case helped a lot with the second one.


Subject(s)
Bartter Syndrome , Cystic Fibrosis , Humans , Cystic Fibrosis/complications , Cystic Fibrosis/genetics , Cystic Fibrosis/diagnosis , Bartter Syndrome/complications , Bartter Syndrome/diagnosis , Bartter Syndrome/genetics , Male , Female , Hyponatremia/etiology , Alkalosis/etiology , Child, Preschool , Child
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