ABSTRACT
Introduction : Les tumeurs plasmocytaires representent 3 a 4 des tumeurs des cavites naso-sinusiennes. Elles necessitent un bilan diagnostique specifique et une prise en charge adequate. Nous nous proposons d'etudier les particularites diagnostiques et therapeutiques des plasmocytomes naso-sinusiens. Materiel et methodes : Notre etude est retrospective comportant 5 cas de plasmocytomes naso-sinusiens confirmes histologiquement. Resultats : Il s'agit de 3 hommes et 2 femmes ages de 32 a 77 ans. Le plasmocytome avait une localisation sphenoidale dans un cas; nasale dans 2 cas; ethmoido-nasale dans un cas et naso-maxillaire dans le cas restant. Il s'agissait d'un myelome multiple dans un cas. Trois patients ont eu une radiotherapie. Celle-ci etait associee a une chimiotherapie dans le cas du myelome multiple et a une exerese chirurgicale dans les 2 autres cas La chirurgie a ete seule dans un cas. La chimiotherapie exclusive a ete proposee dans un cas de plasmocytome localement avance mais le patient a ete perdu de vue. Pour les patients suivis; une seule recidive a ete notee a 18 mois. Conclusion : La presentation clinique des plasmocytomes nasosinusiens est aspecifique. Le diagnostic est confirme par l'histologie. Le pronostic est domine par la presence ou non d'un myelome multiple et par la taille tumorale. Un suivi prolonge est necessaire
Subject(s)
Nasal Cavity , Neoplasms , PlasmacytomaABSTRACT
INTRODUCTION: Peritonsillar abscess is generally seen as a complication of acute tonsillitis in young subjects. It may, however, in rare cases reveal a malignant tumor of the tonsil: most often squamous cell carcinoma or, more rarely, lymphoma. We report a rare case of tonsillar lymphoma revealed by a peritonsillar abscess. CASE REPORT: A 66-year-old woman, without history of recurrent tonsillitis, was admitted for right peritonsillar abscess with fever. She underwent incision-drainage of the abscess with 10 days' intravenous antibiotics. As tonsillar hypertrophy persisted, tonsillectomy was performed; histology with immunohistochemical examination found tonsillar lymphoma. DISCUSSION/CONCLUSION: Possible tumoral etiology should be considered in any peritonsillar abscess occurring in an atypical subject. Acute-stage tonsillectomy enables early diagnosis.
Subject(s)
Lymphoma, Non-Hodgkin/diagnosis , Peritonsillar Abscess/etiology , Tonsillar Neoplasms/diagnosis , Aged , Female , Humans , Lymphoma, Non-Hodgkin/surgery , Tomography, X-Ray Computed , Tonsillar Neoplasms/surgery , TonsillectomySubject(s)
Pemphigus/genetics , Psoriasis/genetics , Adrenal Cortex Hormones/therapeutic use , Adult , Anti-Inflammatory Agents/administration & dosage , Anti-Inflammatory Agents/therapeutic use , Biopsy , Female , Fluorescent Antibody Technique, Direct , Humans , Keratolytic Agents/therapeutic use , Pemphigus/complications , Pemphigus/diagnosis , Pemphigus/drug therapy , Pemphigus/epidemiology , Pemphigus/pathology , Prednisone/administration & dosage , Prednisone/therapeutic use , Psoriasis/complications , Psoriasis/diagnosis , Psoriasis/drug therapy , Psoriasis/pathology , Skin/pathology , Treatment Outcome , Tunisia/epidemiologyABSTRACT
Bleomycin is an antibiotic with antineoplastic pro prieties. It is used in the traitement of many syndromes. The cutaneous toxicity of bleomycin includes many alteration. We report a case of flagellate erythema following the administration of bleomycin in a 57-year-old women with Kaposi sarcoma. She developped linear lesions 6 days after the first dose of bleomycin. Flagellate erythema is a specific reaction to bleomycin therapy wich occurs in susceptible individuals independently of dose, route of administration and type of malignant disease treated. Its occurs in 10 to 35% of the treated patients.