ABSTRACT
Acute pancreatitis during the postpartum period or during pregnancy is rare. Biliary disease is the most common cause of acute pancreatitis, followed by hypertriglyceridemia. We here report the case of a 19-year-old patient with acute pancreatitis occurring 4 weeks after delivery and revealed by epigastralgia radiating to the back, lipasemia more than 36 times the normal limit and etiologic investigation that gave negative results. Early diagnosis of acute pancreatitis during the postpartum period is a challenge for clinicians because it is rare and differential diagnosis includes multiple disorders.
Subject(s)
Hypertriglyceridemia , Pancreatitis , Pregnancy Complications , Acute Disease , Adult , Female , Humans , Pancreatitis/diagnosis , Pancreatitis/etiology , Postpartum Period , Pregnancy , Pregnancy Complications/diagnosis , Pregnancy Complications/etiology , Young AdultABSTRACT
BACKGROUND: Actinomycosis is a rare chronic infection caused by Actinomyces. The abdominopelvic localization of this pathology makes preoperative diagnosis extremely exceptional. The following report is the case of a patient treated for adenocarcinoma of the middle rectum associated with mesorectal actinomycosis. The diagnosis of actinomycosis was made postoperatively. CASE PRESENTATION: A 69-year-old Caucasian male patient was admitted for rectal bleeding. Clinical and paraclinical assessment revealed a middle rectum adenocarcinoma with local extension in the mesorectum. The patient underwent an anterior resection of the rectum by laparotomy after neoadjuvant chemoradiotherapy. Postoperative follow-up was simple. Pathological study of the specimen noted complete sterilization of the rectal adenocarcinoma and the presence of large foci of suppurative necrosis containing actinomycotic grains in the mesorectum. CONCLUSION: Abdominopelvic actinomycosis is a rare pathology and has therefore rarely been dealt with. This issue can lead to unnecessary and mutilating surgery. We report an exceptional coincidence of rectal adenocarcinoma and mesorectal actinomycosis mistaken for mesorectal extension of the cancer.
Subject(s)
Actinomycosis , Adenocarcinoma , Rectal Neoplasms , Actinomycosis/diagnosis , Actinomycosis/therapy , Adenocarcinoma/diagnosis , Adenocarcinoma/therapy , Aged , Humans , Male , Neoadjuvant Therapy , Rectal Neoplasms/diagnosis , Rectal Neoplasms/therapy , Rectum/diagnostic imaging , Rectum/surgeryABSTRACT
BACKGROUND: Radiotherapy associated with chemotherapy is a well-established treatment modality for locally advanced non-small cell lung cancers. Radiation-induced second malignancies, particularly radiation-induced sarcomas, are rare. Some authors reported a recent increase in the incidence of this rare complication, especially because of the improved prognosis and survival of patients after radiotherapy. Pathogenic mechanisms of radiation-induced sarcomas are poorly understood. However, diagnosis criteria are well established. Treatment options must be discussed and adapted to the patient's profile. Surgery in irradiated tissue is challenging, with limited treatment options with chemotherapy and radiotherapy. CASE PRESENTATION: We report the case of a 62-year-old Moroccan man diagnosed as having chondrosarcoma of his right scapula, who was irradiated 10 years ago for stage IIIB non-small cell lung cancer. This case was managed by a complete resection of the tumor with good functional and oncological outcomes. To the best of our knowledge, the scapular location of radiation-induced sarcoma after irradiation for lung cancer has never been described in the literature. CONCLUSION: Radiation-induced sarcoma of the scapula represents a rare situation that must be actively researched to have access to an optimal therapeutic approach.