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Sheng Li Xue Bao ; 76(2): 346-352, 2024 Apr 25.
Article Zh | MEDLINE | ID: mdl-38658383

Programmed death-ligand 1 (PD-L1) is important in maintaining central and peripheral immune tolerance in normal tissues, mediating tumor immune escape and keeping the balance between anti- and pro-inflammatory responses. Inflammation plays an important role in inflammatory lung diseases. This article reviews the research progress and potential clinical value of PD-L1 in inflammatory lung diseases, including acute lung injury, chronic obstructive pulmonary disease, asthma and idiopathic pulmonary fibrosis.


Asthma , B7-H1 Antigen , Pulmonary Disease, Chronic Obstructive , Humans , B7-H1 Antigen/metabolism , B7-H1 Antigen/immunology , Pulmonary Disease, Chronic Obstructive/immunology , Asthma/immunology , Acute Lung Injury/immunology , Inflammation/immunology , Idiopathic Pulmonary Fibrosis/immunology , Idiopathic Pulmonary Fibrosis/metabolism , Lung Diseases/immunology , Lung Diseases/metabolism , Animals
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