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1.
Molecules ; 29(11)2024 May 24.
Article in English | MEDLINE | ID: mdl-38893343

ABSTRACT

Polyphenols are plant secondary metabolites that function mostly as a general stress-induced protective mechanism. Polyphenols have also gained interest due to their beneficial properties for human health. Strawberry leaves represent an agro-industrial waste material with relevant bioactive polyphenol content, which could be incorporated into circular economy strategies. However, due to the low quantities of polyphenols in plants, their production needs to be improved for cost-effective applications. The objective of this research was to compare polyphenol production in strawberry (Fragaria × ananassa cv. Festival) leaves in plants grown in greenhouse conditions and plants grown in vitro, using three possible elicitor treatments (UV irradiation, cold exposure, and cysteine). General vegetative effects were morphologically evaluated, and specific polyphenolic compounds were quantified by UHPLC-DAD-MS/MS. Gallic acid was the most abundant polyphenol found in the leaves, both in vivo and in vitro. The results showed higher amounts and faster accumulation of polyphenols in the in vitro regenerated plants, highlighting the relevance of in vitro tissue culture strategies for producing compounds such as polyphenols in this species and cultivar.


Subject(s)
Fragaria , Plant Leaves , Polyphenols , Fragaria/chemistry , Fragaria/metabolism , Polyphenols/chemistry , Plant Leaves/chemistry , Tandem Mass Spectrometry , Chromatography, High Pressure Liquid , Gallic Acid/chemistry
2.
J Ambul Care Manage ; 47(3): 168-186, 2024.
Article in English | MEDLINE | ID: mdl-38787619

ABSTRACT

In January 2015, the New York City Department of Health and Mental Hygiene launched Harlem Health Advocacy Partners (HHAP), a place-based initiative to demonstrate the capacity of a CHW workforce to improve the health of residents of public housing. The long-term goal of HHAP is to improve the population health of residents of public housing in East and Central Harlem and to close racial gaps in health and social outcomes. A variety of evaluation approaches have been used to assess the initiative. This paper describes the HHAP model and methods for evaluating the program.


Subject(s)
Community Health Workers , New York City , Humans , Program Evaluation , Public Housing , Local Government
3.
Rev. costarric. salud pública ; 25(2): 28-35, jul.-dic. 2016. tab, ilus
Article in Spanish | LILACS | ID: biblio-844769

ABSTRACT

ResumenEn abril del 2002, un grupo de investigadores suecos dio a conocer que algunos alimentos ricos en almidón y pobres en proteínas, sometidos a procesos con temperaturas mayores a 120°C (fritura, horneado, asado y tostado) contenían el pro-cancerígeno conocido como acrilamida. A partir de ese momento, se desató una verdadera carrera investigativa en torno al tema, generando más de 7000 publicaciones científicas relacionadas con el tema, solo en los últimos 4 años.Al día de hoy, las investigaciones realizadas dejan en claro que la formación de acrilamida en los alimentos involucra al aminoácido asparragina y a azúcares reductores, los cuales mediante la reacción de Maillard dan como resultado el mencionado compuesto, denominado actualmente como un contaminante del proceso o un contaminante neo formado.La investigación realizada, se puede decir tiene tres vertientes claramente definidas, una es explicar porque se da la presencia de acrilamida en los alimentos, otra se enfoca en el desarrollo de protocolos y tecnología de punta para la detección de la sustancia en diversos alimentos y la tercera tiene que ver con las medidas a tomar para mitigar la aparición de acrilamida en sustratos alimenticios. Esta revisión tiene como objetivo, brindar al lector una visión actualizada sobre estas tres vertientes anteriormente citadas.


AbstractIn April 2002, a Swedish group or researches informed that some food products with high starch and low protein constitution and submitted to temperature processes above 120°C contained a pro cancerigenous substance known as acrylamide. From this moment on, and until actual times, a research race around the theme has been established.Up to the date, research done clearly describes the formation of acrylamide in food from asparagine and reducing sugars, through Maillard's reaction, and is known as a process contaminant or a neo formed contaminant.Actual research on the theme has three different approaches, one that explains the presence of acrylamide in food, a second one that focusses in the development of protocols and technology for its detection in food and a third one that tries to develop mitigating measures for the appearance of acrylamide in food substrates. The aim of this review is to bring to the reader an actualized vision of these three approaches.


Subject(s)
Acrylamides/adverse effects , Maillard Reaction , Costa Rica , Diet/adverse effects
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