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1.
Pathologica ; 110(2): 103-105, 2018 Sep.
Article in English | MEDLINE | ID: mdl-30546146

ABSTRACT

Extraskeletal chondrosarcoma is a rare malignant tumor. The well differentiated histological type, which is found primary in soft tissue, is extremely rare. This report  describes the case of a 58-year-old woman presented with a large palpable mass in the right buttock. Imaging studies revealed a well-defined soft tissue mass, with extensive calcification. A histological examination after surgical resection confirmed the diagnosis of well-differentiated extraosseous chondrosarcoma. The outcome was favorable, without recurrence or metastasis.


Subject(s)
Cell Differentiation , Chondrosarcoma/pathology , Neoplasms, Connective and Soft Tissue/pathology , Biopsy , Buttocks , Chondrosarcoma/diagnostic imaging , Chondrosarcoma/surgery , Diagnosis, Differential , Female , Humans , Magnetic Resonance Imaging , Middle Aged , Neoplasms, Connective and Soft Tissue/diagnostic imaging , Neoplasms, Connective and Soft Tissue/surgery , Predictive Value of Tests , Tomography, X-Ray Computed , Tumor Burden
2.
Pathologica ; 106(2): 73-6, 2014 Jun.
Article in English | MEDLINE | ID: mdl-25291872

ABSTRACT

BACKGROUND: Uterine tumours resembling ovarian sex-cord tumours (UTROSCT) are very rare, benign uterine tumours, composed solely of sex cord elements. These tumours have a polyphenotypic immunophentype that favours a derivation from uterine mesenchymal stem cells. CASE REPORT: A 43-year-old female presented with recurrent vaginal bleeding. On hysteroscopy, she had multiple endometrial and cervical polyps that were removed endoscopically. Histologically, the specimen contained epithelioid cells arranged in tubules, trabeculae and anastomosing cords, without significant cellular atypia or mitotic activity. Immunohistochemical studies were performed. The tumour was found to be diffusely positive for vimentin, calretinin and desmin, focally positive for cytokeratin, CD99 and inhibin and negative for chromogranin and CD10. A subsequent total hysterectomy was performed and revealed neoplastic infiltration of the myometrium. CONCLUSION: A polyphenotypic immunophenotype is a characteristic feature of UTROSCT, and may be helpful in diagnosis and in exclusion of other lesions. Familiarity with this tumour by gynaecologists and pathologists is essential to avoid misdiagnosis:correct diagnosis of this neoplasm is important in patient management.


Subject(s)
Endometrial Neoplasms/pathology , Ovarian Neoplasms/pathology , Polyps/pathology , Sex Cord-Gonadal Stromal Tumors/pathology , Uterine Cervical Neoplasms/pathology , Adult , Biomarkers, Tumor/analysis , Biopsy , Endometrial Neoplasms/chemistry , Endometrial Neoplasms/surgery , Female , Humans , Hysteroscopy , Immunohistochemistry , Polyps/chemistry , Polyps/surgery , Predictive Value of Tests , Uterine Cervical Neoplasms/chemistry , Uterine Cervical Neoplasms/surgery
3.
Pathologica ; 106(4): 330-4, 2014 Dec.
Article in English | MEDLINE | ID: mdl-25845049

ABSTRACT

Mixed stromal and smooth muscle uterine tumours, defined as those containing at least 30% of each component as seen by routine light microscopy, are rare. This report describes the morphological features of two such tumours diagnosed in 44-year-old and 50-year-old females complaining from recurrent uterine bleeding that was unresponsive to medical treatment. Morphological and immunohistochemical evaluations were performed, and a final diagnosis of mixed endometrial stromal nodule and smooth muscle tumour of the uterus was rendered in both cases.


Subject(s)
Endometrial Neoplasms/pathology , Mixed Tumor, Malignant/pathology , Smooth Muscle Tumor/pathology , Uterine Neoplasms/pathology , Uterus/pathology , Adult , Diagnosis, Differential , Endometrial Neoplasms/complications , Endometrial Neoplasms/diagnosis , Female , Humans , Middle Aged , Mixed Tumor, Malignant/diagnosis , Smooth Muscle Tumor/complications , Smooth Muscle Tumor/diagnosis , Uterine Neoplasms/diagnosis
4.
J Gynecol Obstet Biol Reprod (Paris) ; 40(6): 541-8, 2011 Oct.
Article in French | MEDLINE | ID: mdl-21764225

ABSTRACT

OBJECTIVES: To assess the postoperative morbidity of a technique for caesarean section without closing the visceral and parietal peritoneum. PATIENTS AND METHODS: We conducted a prospective cohort study randomized 252 patients over a period of four months (from March 1 to June 30, 2009). We studied the early postoperative morbidity. RESULTS: Among the 252 patients, 137 were included in the group "with peritonisation" and 115 in the group "without peritonisation". Clinical and hematology maternal characteristics were comparable in both groups. The duration of intervention was reduced significantly in the absence of peritonisation (31.1 instead of 41.4 minutes; P<0.001). The postoperative pain was less but not significant between h0 and h12, however it is significant at h18, h24 and h30 in the absence of peritonisation (respectively 2.37 versus 2.81; P=0.030; 1.98 versus 2.37; P<0.001 and 1.38 versus 1.72; P=0.018). Resumption of transit was significantly faster "without peritonisation" (24.3 versus 24.7 hours; P<0.001). However, there is no significant difference between the two groups as regards the immediate postoperative complications. CONCLUSION: The absence of visceral and parietal peritoneum shortens the operative time and favors an earlier resumption of transit. It also decreases pain symptoms. We therefore recommend not to suture the parietal and visceral peritoneum during cesarean section.


Subject(s)
Cesarean Section/methods , Cesarean Section/trends , Peritoneum/surgery , Suture Techniques/trends , Work Simplification , Adult , Anti-Bacterial Agents/therapeutic use , Cesarean Section/statistics & numerical data , Cohort Studies , Female , Gastrointestinal Transit/physiology , Humans , Length of Stay/statistics & numerical data , Morbidity , Pain, Postoperative/epidemiology , Perioperative Period , Postoperative Complications/epidemiology , Pregnancy , Tunisia
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