Your browser doesn't support javascript.
loading
: 20 | 50 | 100
1 - 20 de 26
1.
J Prev (2022) ; 45(3): 467-482, 2024 Jun.
Article En | MEDLINE | ID: mdl-38564144

This longitudinal study aimed to analyze the evolution of patterns of daily activities (physical activity time, screen usage time, and sleep hours) in European youth during school closure due to the COVID-19 health crisis. Participants were 624 caregivers of children and adolescents aged 3-18 from Italy, Spain, and Portugal. Evaluations were online, and four time-points were considered: retrospective measurement of daily activities before confinement (T1), and two (T2), five (T3), and eight (T4) weeks after starting the lockdown. Generally accepted international guidelines on physical activity time, screen usage time, and hours of sleep by age group were used to determine whether the pattern might increase the risk for ill health or not. To estimate the evolution of daily activities, generalized estimating equations (GEE) were used. The percentage of children who practiced less than 60 min of daily exercise increased significantly from before home confinement (47.8%) to T2 (86.4%); it slightly decreased at T3 (79.8%), and remained stable at T4 (76.1%). The percentage of children who made excessive use of screens (according to their age group) significantly increased from T1 to T2 and remained stable and high in the rest of the evaluations. The percentage of children who slept fewer or more hours than recommended for their age group remained stable between T1 and T4, although there was a significant increase at T3. In general, results found unhealthier behaviors as confinement was extended. Results are discussed in order to find strategies for promoting healthy daily activities for future pandemics.


COVID-19 , Exercise , Screen Time , Sleep , Humans , COVID-19/epidemiology , COVID-19/prevention & control , Child , Longitudinal Studies , Adolescent , Male , Female , Sleep/physiology , Child, Preschool , SARS-CoV-2 , Schools , Europe/epidemiology , Retrospective Studies , Portugal/epidemiology , Quarantine
2.
J Appl Dev Psychol ; 79: 101390, 2022.
Article En | MEDLINE | ID: mdl-35095148

The present study aimed to compare psychological symptoms and coping strategies in 1480 preschoolers, schoolchildren, and adolescents during home confinement due to COVID-19. We enrolled parents from Italy, Portugal, and Spain who completed a survey between the second and fourth week of lockdown. The results showed that preschoolers displayed more sleeping difficulties, temper tantrums, and dependency while adolescents' reactions were more related to COVID-19 worries and uncertainty. Schoolchildren showed more difficulty in concentrating. Adolescent girls showed higher anxiety levels than schoolchildren boys. Schoolchildren relied more on emotion-oriented strategies, which were linked to increased internalizing and externalizing symptoms in all ages. Task-oriented strategies, regardless of the child's age, work best to cope with stress. Our findings provide information for professionals and parents about children's most common and adaptive coping strategies according to age. Furthermore, they contribute to the early detection of long-term psychological maladjustment in children.

3.
Child Psychiatry Hum Dev ; 53(5): 853-862, 2022 10.
Article En | MEDLINE | ID: mdl-34173126

Aiming to slow down the spread of the COVID-19, a lockdown was declared in the first term of 2020 in many European countries, applying different restrictions measures. Although the psychological effects of home confinement in children have been described, there is a lack of longitudinal research examining the impact of the confinement over time. The present study analyzes the evolution of the psychological wellbeing of children and adolescents from three European countries with different restrictions. Parents of 624 Italian, Spanish, and Portuguese children and adolescents aged 3 to 18 years old completed the "Impact Scale of COVID-19 and Home Confinement on Children and Adolescents" two, five, and eight weeks after the lockdown. Results show a different pattern for each country. Children from Italy, the first European country that applied a lockdown, were better adapted than Spanish and Portuguese children the first two weeks after confinement but they were more psychologically impacted by home confinement at the eight-week assessment. Portuguese children, who followed a general duty of home confinement, were the best adapted to the situation, with no significant differences over time. A significant change was found in anxiety symptoms in Spanish children, with a decrease at the last assessment. Findings suggest that long confinements and hard restrictions affect children, so prevention measures should be applied during confinements to prevent psychological problems in children.


COVID-19 , Mental Disorders , Adolescent , COVID-19/epidemiology , COVID-19/prevention & control , COVID-19/psychology , Child , Child, Preschool , Communicable Disease Control , Humans , Italy/epidemiology , Longitudinal Studies , Mental Disorders/epidemiology , Portugal/epidemiology , Spain/epidemiology
5.
Front Psychol ; 12: 565657, 2021.
Article En | MEDLINE | ID: mdl-33828499

The COVID-19 pandemic and the quarantine undergone by children in many countries is a stressful situation about which little is known to date. Children and adolescents' behaviors to cope with home confinement may be associated with their emotional welfare. The objectives of this study were: (1) to examine the coping strategies used out by children and adolescents during the COVID-19 health crisis, (2) to analyze the differences in these behaviors in three countries, and (3) to examine the relationship between different coping modalities and adaptation. Participants were 1,480 parents of children aged 3-18 years from three European countries (n Spain = 431, n Italy = 712, and n Portugal = 355). The children's mean age was 9.15 years (SD = 4.27). Parents completed an online survey providing information on symptoms and coping behaviors observed in their children. The most frequent coping strategies were accepting what is happening (58.9%), collaborating with quarantine social activities (e.g., drawings on the windows, supportive applauses) (35.9%), acting as if nothing is happening (35.5%), highlighting the advantages of being at home (35.1%), and not appearing to be worried about what is happening (30.1%). Compared to Italian and Spanish children, Portuguese children used a sense of humor more frequently when their parents talked about the situation. Acting as if nothing was happening, collaborating with social activities, and seeking comfort from others were more likely in Spanish children than in children from the other countries. Compared to Portuguese and Spanish children, Italian children did not seem worried about what was happening. Overall, an emotional-oriented coping style was directly correlated with a greater presence of anxious symptoms, as well as to mood, sleep, behavioral, and cognitive alterations. Task-oriented and avoidance-oriented styles were related to better psychological adaptation (considered a low presence of psychological symptoms). Results also show that unaffected children or children with a lower level of impact were more likely to use strategies based on a positive focus on the situation. This study provides interesting data on the strategies to be promoted by parents to cope with the COVID-19 health crisis in children.

6.
Psicothema (Oviedo) ; 33(1): 125-130, feb. 2021. tab
Article En | IBECS | ID: ibc-196951

BACKGROUND: Despite being necessary to delay the spread of COVID-19, home confinement could have affected the emotional well-being of children and adolescents. Knowing which variables are involved in anxiety and depressive symptoms could help to prevent young people's psychological problems related to lockdown as early as possible. This cross-sectional study aims to examine anxiety and depressive symptomatology in Italian, Spanish, and Portuguese children and adolescents in order to determine which variables are related to poorer well-being during the pandemic. METHOD: The parents of 515 children, aged 3-18 years old, completed an online survey. Children's anxiety symptoms were assessed using the Spence Children's Anxiety Scale-Parent Version, and depressive symptoms were measured with the Short Mood and Feelings Questionnaire-Parent Version. RESULTS: We found differences in anxiety and depression between countries, with higher anxiety scores in Spanish children, and higher depression scores in Spanish and Italian children compared to the Portuguese. Anxiety and depressive symptoms were more likely in children whose parents reported higher levels of stress. CONCLUSIONS: These findings are discussed in the light of detecting and supporting affected children as early as possible


ANTECEDENTES: a pesar de ser necesario para retrasar la propagación del COVID-19, el confinamiento podría haber afectado al bienestar emocional de niños y adolescentes. Conocer qué variables están involucradas en la ansiedad y depresión podría ayudar a prevenir en los niños los problemas psicológicos asociados al confinamiento lo antes posible. Este estudio transversal tiene como objetivo examinar la sintomatología ansiosa y depresiva en niños y adolescentes italianos, españoles y portugueses, para detectar qué variables están relacionadas con un peor bienestar durante la pandemia. MÉTODO: los padres de 515 niños de 3 a 18 años completaron una evaluación online. Los síntomas de ansiedad de los niños se evaluaron con la Spence Children's Anxiety Scale-Parent Version, y los síntomas depresivos con el Short Mood and Feelings Questionnaire-Parent Version. RESULTADOS: se hallaron diferencias en la ansiedad y la depresión entre países, con mayor ansiedad en los niños españoles, y mayor sintomatología depresiva en los niños españoles e italianos, en comparación con los portugueses. Los síntomas de ansiedad y depresión eran más probables en niños cuyos padres informaron de un mayor nivel de estrés. CONCLUSIONES: estos hallazgos se discuten con el propósito de detectar y apoyar a los niños afectados lo antes posible


Humans , Male , Female , Child, Preschool , Child , Adolescent , Coronavirus Infections/psychology , Pneumonia, Viral/psychology , Pandemics , Anxiety/psychology , Depression/psychology , Quarantine/psychology , Cross-Cultural Comparison , Surveys and Questionnaires
8.
Psicothema ; 33(1): 125-130, 2021 02.
Article En | MEDLINE | ID: mdl-33453745

BACKGROUND: Despite being necessary to delay the spread of COVID-19, home confinement could have affected the emotional well-being of children and adolescents. Knowing which variables are involved in anxiety and depressive symptoms could help to prevent young people's psychological problems related to lockdown as early as possible. This cross-sectional study aims to examine anxiety and depressive symptomatology in Italian, Spanish, and Portuguese children and adolescents in order to determine which variables are related to poorer well-being during the pandemic. METHOD: The parents of 515 children, aged 3-18 years old, completed an online survey. Children's anxiety symptoms were assessed using the Spence Children's Anxiety Scale-Parent Version, and depressive symptoms were measured with the Short Mood and Feelings Questionnaire-Parent Version. RESULTS: We found differences in anxiety and depression between countries, with higher anxiety scores in Spanish children, and higher depression scores in Spanish and Italian children compared to the Portuguese. Anxiety and depressive symptoms were more likely in children whose parents reported higher levels of stress. CONCLUSIONS: These findings are discussed in the light of detecting and supporting affected children as early as possible.


Anxiety/epidemiology , COVID-19 , Depression/epidemiology , Adolescent , Child , Child, Preschool , Cross-Sectional Studies , Cultural Characteristics , Female , Humans , Italy/epidemiology , Male , Portugal/epidemiology , Quarantine , Spain/epidemiology
9.
Front Psychiatry ; 11: 570164, 2020.
Article En | MEDLINE | ID: mdl-33343415

The coronavirus disease (COVID-19) pandemic forced the home confinement of the majority of population around the world, including a significant number of children and adolescents, for several weeks in 2020. Negative psychological effects have been identified in adults, but research about the impact of this type of social distancing measure on children and adolescents is scarce. The present study aimed to describe and compare the immediate psychological and behavioral symptoms associated with COVID-19 quarantine in children and adolescents from three southern European countries with different levels of restrictions (Italy, Spain, and Portugal). Parents of 1,480 children and adolescents (52.8% boys) between 3 and 18 years old (M = 9.15, SD = 4.27) participated in the study. An online survey using snowball sampling techniques was conducted during 15 days between March and April 2020, representing the early phase of the quarantine associated with COVID-19 outbreak. Parents answered questionnaires about sociodemographic data, housing conditions, immediate psychological responses during quarantine (e.g., anxiety, mood, sleep, and behavioral alterations), patterns of use of screens, daily physical activity, and sleep hours before and during the quarantine. The results revealed an increase in children's psychological and behavioral symptoms, increased screen-time, reduced physical activity, and more sleep hours/night. Italian children presented less psychological and behavioral symptoms compared with Portuguese and Spanish children. In general, hierarchical multiple regressions revealed that having an outdoor exit in the house (e.g., garden, terrace) contributed to lower levels of psychological and behavioral symptomatology. Future studies are needed to identify family and individual variables that can better predict children and adolescents' well-being during and after quarantine. Recommendations for families and implications for practice are discussed.

10.
Neurocirugía (Soc. Luso-Esp. Neurocir.) ; 31(4): 184-194, jul.-ago. 2020. ilus
Article Es | IBECS | ID: ibc-193899

INTRODUCCIÓN: La cirugía de los tumores cerebrales se ha implementado en los últimos años con nuevas técnicas de imagen intraoperatoria, que tratan de mejorar la resección tumoral, aunque conllevan un aumento de recursos. Con el fin de hacer una actualización de este tema, se ha elaborado este manuscrito desde el grupo de tumores de la Sociedad Española de Neurocirugía. MATERIAL Y MÉTODOS: Se ha propuesto a expertos en el uso de cada una de las técnicas intraoperatorias más empleadas en la cirugía de los tumores cerebrales, la descripción de la técnica y una breve revisión de la literatura. Se describirán indicaciones de uso, sus ventajas e inconvenientes basados en la experiencia clínica y en lo publicado en la literatura. RESULTADOS: La técnica de imagen intraoperatoria más consistente sería la resonancia de bajo y alto campo, pero a su vez es la que supone un mayor gasto de recursos. La ecografía intraoperatoria navegada es portátil y tiene un menor coste, aunque discrimina peor los tumores de alto grado y es observador-dependiente. Las técnicas de fluorescencia más empleadas son el 5-aminolevulínico para gliomas de alto grado y la fluoresceína, de utilidad en lesiones que rompen la barrera hematoencefálica. Por último, la TAC intraoperatoria es la más versátil en el quirófano de neurocirugía, pero tiene menos indicaciones en la cirugía neurooncológica. CONCLUSIONES: Las técnicas de imagen intraoperatoria se emplean cada vez con más frecuencia en la cirugía de los tumores cerebrales, y el neurocirujano debe valorar su posible uso en función de sus recursos y las necesidades de cada paciente


INTRODUCTION: New intraoperative imaging techniques, which aim to improve tumour resection, have been implemented in recent years in brain tumour surgery, although they lead to an increase in resources. In order to carry out an update on this topic, this manuscript has been drafted by a group from the Sociedad Española de Neurocirugía (Spanish Society of Neurosurgery). MATERIAL AND METHODS: Experts in the use of each one of the most-used intraoperative techniques in brain tumour surgery were presented with a description of the technique and a brief review of the literature. Indications for use, their advantages and disadvantages based on clinical experience and on what is published in the literature will be described. RESULTS: The most robust intraoperative imaging technique appears to be low- and high-field magnetic resonance imaging, but this is the technique which results in the greatest expenditure. Intraoperative ultrasound navigation is portable and less expensive, but it provides poorer differentiation of high-grade tumours and is observer-dependent. The most-used fluorescence techniques are 5-aminolevulinic acid for high-grade gliomas and fluorescein, useful in lesions which rupture the blood-brain barrier. Last of all, intraoperative CT is more versatile in the neurosurgery operating theatre, but it has fewer indications in neuro-oncology surgery. CONCLUSIONS: Intraoperative imaging techniques are used with increasingly greater frequency in brain tumour surgery, and the neurosurgeon should assess their possible use depending on their resources and the needs of each patient


Humans , Brain Neoplasms/surgery , Neurosurgical Procedures , Image Processing, Computer-Assisted , Monitoring, Intraoperative/instrumentation , Magnetic Resonance Imaging/instrumentation , Monitoring, Intraoperative/standards , Magnetic Resonance Imaging/standards
11.
Neurocirugia (Astur : Engl Ed) ; 31(4): 184-194, 2020.
Article En, Es | MEDLINE | ID: mdl-31836283

INTRODUCTION: New intraoperative imaging techniques, which aim to improve tumour resection, have been implemented in recent years in brain tumour surgery, although they lead to an increase in resources. In order to carry out an update on this topic, this manuscript has been drafted by a group from the Sociedad Española de Neurocirugía (Spanish Society of Neurosurgery). MATERIAL AND METHODS: Experts in the use of each one of the most-used intraoperative techniques in brain tumour surgery were presented with a description of the technique and a brief review of the literature. Indications for use, their advantages and disadvantages based on clinical experience and on what is published in the literature will be described. RESULTS: The most robust intraoperative imaging technique appears to be low- and high-field magnetic resonance imaging, but this is the technique which results in the greatest expenditure. Intraoperative ultrasound navigation is portable and less expensive, but it provides poorer differentiation of high-grade tumours and is observer-dependent. The most-used fluorescence techniques are 5-aminolevulinic acid for high-grade gliomas and fluorescein, useful in lesions which rupture the blood-brain barrier. Last of all, intraoperative CT is more versatile in the neurosurgery operating theatre, but it has fewer indications in neuro-oncology surgery. CONCLUSIONS: Intraoperative imaging techniques are used with increasingly greater frequency in brain tumour surgery, and the neurosurgeon should assess their possible use depending on their resources and the needs of each patient.


Brain Neoplasms , Glioma , Neurosurgery , Brain Neoplasms/diagnostic imaging , Brain Neoplasms/surgery , Glioma/diagnostic imaging , Glioma/surgery , Humans , Magnetic Resonance Imaging , Neuronavigation , Neurosurgical Procedures
12.
Materials (Basel) ; 12(21)2019 Oct 24.
Article En | MEDLINE | ID: mdl-31653029

A fully-unsupervised learning algorithm for reaching self-organization in neuromorphic architectures is provided in this work. We experimentally demonstrate spike-timing dependent plasticity (STDP) in Oxide-based Resistive Random Access Memory (OxRAM) devices, and propose a set of waveforms in order to induce symmetric conductivity changes. An empirical model is used to describe the observed plasticity. A neuromorphic system based on the tested devices is simulated, where the developed learning algorithm is tested, involving STDP as the local learning rule. The design of the system and learning scheme permits to concatenate multiple neuromorphic layers, where autonomous hierarchical computing can be performed.

13.
Fertil Steril ; 110(7): 1387-1397, 2018 12.
Article En | MEDLINE | ID: mdl-30446247

OBJECTIVE: To determine whether metabolic imaging with the use of fluorescence lifetime imaging microscopy (FLIM) identifies metabolic differences between normal oocytes and those with metabolic dysfunction. DESIGN: Experimental study. SETTING: Academic research laboratories. PATIENT(S): None. INTERVENTION(S): Oocytes from mice with global knockout of Clpp (caseinolytic peptidase P; n = 52) were compared with wild-type (WT) oocytes (n = 55) as a model of severe oocyte dysfunction. Oocytes from old mice (1 year old; n = 29) were compared with oocytes from young mice (12 weeks old; n = 35) as a model of mild oocyte dysfunction. MAIN OUTCOME MEASURE(S): FLIM was used to measure the naturally occurring nicotinamide adenine dinucleotide dehydrogenase (NADH) and flavin adenine dinucleotide (FAD) autofluorescence in individual oocytes. Eight metabolic parameters were obtained from each measurement (4 per fluorophore): short (τ1) and long (τ2) fluorescence lifetime, fluorescence intensity (I), and fraction of the molecule engaged with enzyme (F). Reactive oxygen species (ROS) levels and blastocyst development rates were measured to assess illumination safety. RESULT(S): In Clpp-knockout oocytes compared with WT, FAD τ1 and τ2 were longer and I was higher, NADH τ2 was longer, and F was lower. In old oocytes compared with young ones, FAD τ1 was longer and I was lower, NADH τ1 and τ2 were shorter, and I and F were lower. FLIM did not affect ROS levels or blastocyst development rates. CONCLUSION(S): FLIM parameters exhibit strong differentiation between Clpp-knockout versus WT, and old versus young oocytes. FLIM could potentially be used as a noninvasive tool to assess mitochondrial function in oocytes.


Mitochondria/pathology , Mitochondria/physiology , Molecular Imaging/methods , Oocytes/metabolism , Oocytes/ultrastructure , Animals , Cells, Cultured , Computer Systems , Embryo Culture Techniques , Embryo, Mammalian , Embryonic Development , Endopeptidase Clp/genetics , Female , Flavin-Adenine Dinucleotide/analysis , Flavin-Adenine Dinucleotide/metabolism , Fluorescence , Male , Maternal Age , Mice , Mice, Inbred C57BL , Mice, Knockout , Microscopy, Fluorescence , Mitochondria/metabolism , Mitochondria/ultrastructure , NAD/analysis , NAD/metabolism , Oocytes/cytology , Reactive Oxygen Species/analysis , Reactive Oxygen Species/metabolism
14.
Clin Neuropharmacol ; 40(3): 103-107, 2017.
Article En | MEDLINE | ID: mdl-28452905

OBJECTIVES: This study assesses the effect of levodopa/carbidopa intestinal infusion gel (LCIIG) as an additional treatment in patients with advanced idiopathic Parkinson disease (PD) previously treated with deep brain stimulation (DBS). METHODS: Prospective study of advanced PD patients, satisfactorily treated with bilateral DBS of the subthalamic nucleus, who had developed refractory symptoms and LCIIG was added. Controls were advanced PD patients treated with LCIIG. Measurements included the Unified Parkinson Disease Rating Scale (UPDRS)-III and the UPDRS axial compound. RESULTS: There were 19 patients in the DBS-LCIIG therapy group and 21 in the control group. The DBS-LCIIG patients were younger and had disease duration longer than controls. The median time from DBS to gastrostomy was 7.8 years (range, 2-12 years). In both study groups, the mean scores of the UPDRS-III and UPDRS axial subscales improved significantly after LCIIG treatment (DBS-LCIIG group: UPDRS-III, 62.0 [15.7] vs 30.9 [12.1]; UPDRS axial, 24.7 [4.9] vs 10.2 [2.7]; P < 0.0005 for all comparisons). There were no differences in adverse events between the groups. In the follow-up of the DBS-LCIIG group. 5 patients discontinued DBS-LCIIG therapy and returned to DBS, 5 discontinued DBS and were maintained with LCIIG, and the remaining 9 continued with DBS-LCIIG therapy. Mean time until discontinuation in the double DBS-LCIIG group was 891 days. The main risk factors for discontinuation were age at the beginning of LCIIG and severity of the UPDRS axial subscale. CONCLUSIONS: Levodopa/carbidopa intestinal infusion gel therapy may be a valuable option in selected patients with advanced PD who develop refractory symptoms after long-term subthalamic nucleus-DBS.


Antiparkinson Agents/administration & dosage , Carbidopa/administration & dosage , Deep Brain Stimulation , Gastrostomy , Levodopa/administration & dosage , Parkinson Disease/drug therapy , Parkinson Disease/therapy , Patient Acceptance of Health Care , Age Factors , Aged , Antiparkinson Agents/adverse effects , Antiparkinson Agents/therapeutic use , Carbidopa/adverse effects , Carbidopa/therapeutic use , Combined Modality Therapy/adverse effects , Deep Brain Stimulation/adverse effects , Drug Combinations , Duodenum , Female , Follow-Up Studies , Gastrostomy/adverse effects , Gels , Humans , Intubation, Gastrointestinal , Levodopa/adverse effects , Levodopa/therapeutic use , Male , Middle Aged , Parkinson Disease/physiopathology , Patient Dropouts , Prospective Studies , Severity of Illness Index , Spain , Subthalamic Nucleus
15.
Stereotact Funct Neurosurg ; 95(2): 102-106, 2017.
Article En | MEDLINE | ID: mdl-28297702

BACKGROUND: It has been described that many Charcot-Marie-Tooth syndrome type 2 patients are affected by a very disabling type of tremor syndrome, the pathophysiology of which remains unclear. Deep brain stimulation (DBS) has been successfully applied to treat most types of tremors by implanting electrodes in the ventral intermediate nucleus of the thalamus (Vim). METHODS: We used DBS applied to the Vim in 2 patients with severe axonal inherited polyneuropathies who developed a disabling tremor. RESULTS: Both patients responded positively to stimulation, with a marked reduction of the tremor and with an improvement of their quality of life. CONCLUSION: We report 2 cases of tremor associated with a hereditary neuropathy with a good response to DBS.


Charcot-Marie-Tooth Disease/surgery , Deep Brain Stimulation/methods , Quality of Life , Thalamus/surgery , Tremor/surgery , Charcot-Marie-Tooth Disease/complications , Charcot-Marie-Tooth Disease/physiopathology , Female , Humans , Male , Middle Aged , Time Factors , Treatment Outcome , Tremor/etiology , Tremor/physiopathology
16.
Stereotact Funct Neurosurg ; 94(6): 379-386, 2016.
Article En | MEDLINE | ID: mdl-27846626

BACKGROUND: Posttraumatic tremor (PTT) is the most frequent movement disorder secondary to cranioencephalic trauma and can be persistent and disabling. OBJECTIVES: We review and assess the efficacy of deep brain stimulation (DBS) at the VIM/VOP/ZI (ventralis intermedius/ventrooralis posterior/zona incerta) complex level for the treatment of PTT. METHODS: During the period from 1999 to 2014, 5 patients diagnosed with PTT were selected who had experienced a major deterioration in their quality of life without improvement during medical treatment for more than 1 year. They underwent surgery for DBS at the VIM/VOP/ZI complex level, and the modified tremor scale before and after surgery was used for their follow-up. RESULTS: Each patient showed improvements in their symptoms after DBS compared with baseline, which was moderate (II) in 2 cases and marked (III) in the other cases. All of the improvements were maintained with chronic DBS, without tremor rebound. CONCLUSIONS: Stimulation of the contralateral VIM/VOP/ZI complex resulted in a noticeable improvement in tremor and recovery of independence in basic daily activities in patients with PTT.


Brain Injuries, Traumatic/surgery , Deep Brain Stimulation/methods , Movement Disorders/surgery , Tremor/surgery , Adolescent , Adult , Brain Injuries, Traumatic/complications , Brain Injuries, Traumatic/diagnostic imaging , Deep Brain Stimulation/trends , Female , Follow-Up Studies , Humans , Male , Movement Disorders/diagnostic imaging , Movement Disorders/etiology , Tremor/diagnostic imaging , Tremor/etiology , Young Adult
17.
Sci Rep ; 6: 33490, 2016 09 21.
Article En | MEDLINE | ID: mdl-27649784

We report on the detailed electrical investigation of all-inkjet-printed thin-film transistor (TFT) arrays focusing on TFT failures and their origins. The TFT arrays were manufactured on flexible polymer substrates in ambient condition without the need for cleanroom environment or inert atmosphere and at a maximum temperature of 150 °C. Alternative manufacturing processes for electronic devices such as inkjet printing suffer from lower accuracy compared to traditional microelectronic manufacturing methods. Furthermore, usually printing methods do not allow the manufacturing of electronic devices with high yield (high number of functional devices). In general, the manufacturing yield is much lower compared to the established conventional manufacturing methods based on lithography. Thus, the focus of this contribution is set on a comprehensive analysis of defective TFTs printed by inkjet technology. Based on root cause analysis, we present the defects by developing failure categories and discuss the reasons for the defects. This procedure identifies failure origins and allows the optimization of the manufacturing resulting finally to a yield improvement.

18.
Rev. neurol. (Ed. impr.) ; 63(3): 97-102, 1 ago., 2016. tab, graf
Article Es | IBECS | ID: ibc-154992

Objetivo. Describir las alteraciones de la marcha e inestabilidad postural en un grupo de pacientes con enfermedad de Parkinson (EP) avanzada. Pacientes y métodos. Se analizó la marcha de pacientes con EP en estadio avanzado on medicación. Por medio de un sistema de análisis computarizado del movimiento, se estudiaron las variables cinemáticas: cadencia, número de ciclos con apoyo correcto (ciclos HFPS), número de ciclos totales, duración de las fases del ciclo, electromiografía, y goniometría de rodilla y tobillo. La valoración clínica del equilibrio y la inestabilidad postural se completó con los tests Tinetti y Timed Up & Go. Resultados. El análisis mostró alteraciones en los parámetros espaciotemporales con respecto a los rangos de normalidad: disminución de los ciclos HFPS, aumento del número total de ciclos y alteración de la cadencia en muchos pacientes, y conservación de la cadencia media dentro de los límites de la normalidad, aumento de la duración de la fase de apoyo, disminución del apoyo monopodal y alteración del rango articular de la rodilla y el tobillo. Asimismo, se observó una alteración en las puntuaciones obtenidas en las escalas clínicas, que mostraban un aumento del factor de riesgo de caídas y dependencia leve. Conclusión. La cuantificación mediante análisis objetivo de las variables cinéticas y cinemáticas en los pacientes con EP puede emplearse como herramienta para establecer la influencia de las distintas alternativas terapéuticas en el trastorno de la marcha (AU)


Aim. To describe the gait disorders and postural instability in a group of patients with advanced Parkinson’s disease (PD). Patients and Methods. Gait was analysed in patients in advanced stages of PD on medication. Using a computerised analysis system, we studied the kinematic variables: cadence, number of correct gait cycles (HFPS cycles), total number of cycles, duration of the phases of the cycle, electromyography and a goniometric study of the knee and the ankle. The clinical appraisal of balance and postural instability was completed with the Tinetti and Timed Up & Go tests. Results. The analysis showed alterations in the spatio-temporal parameters with respect to the ranges considered to be normal: reduction of the HFPS cycles, increase in the total number of cycles and alteration of the cadence in many patients. It also revealed that the mean cadence was kept within the limits of normal values, an increase in the duration of the contact phase, reduction of monopodal support and alteration of the joint range of motion of the knee and the ankle. Likewise, changes are also observed in the scores obtained on the clinical scales, which show an increase in the risk factor for falls and mild dependence. Conclusion. Quantification by objective analysis of the kinetic and kinematic variables in patients with PD can be used as a tool to establish the influence of the different therapeutic alternatives in gait disorders (AU)


Humans , Male , Female , Adult , Middle Aged , Aged , Gait Disorders, Neurologic/complications , Gait Disorders, Neurologic/diagnosis , Gait Apraxia/diagnosis , Gait/physiology , Parkinson Disease/complications , Risk Factors , Levodopa/therapeutic use , 24960/methods , 24960/statistics & numerical data , Biomechanical Phenomena/radiation effects , Arthrometry, Articular/methods , Muscle Rigidity/complications , Tremor/complications , Electromyography/methods , Arthrometry, Articular , Hypokinesia/complications , Hypokinesia/diagnosis
19.
Child Psychiatry Hum Dev ; 47(5): 759-70, 2016 10.
Article En | MEDLINE | ID: mdl-26615594

This study aims to analyze the mediating role of coping strategies in the relationship between family functioning and youth maladjustment. A community sample of 341 adolescents (M = 15.11 years old; SD = 1.71) completed self-report measures about such variables. Results showed that a perception of an inadequate family functioning was associated with the use of maladaptive coping strategies, as well as with youth psychological maladjustment. The results also revealed that rumination and support-seeking mediated the relationship between family functioning and internalizing behavior, and hostile expression of feelings played a mediating role between family functioning and externalizing behavior. No gender differences were found in the relationship between variables. This study emphasizes the importance of coping strategies used by adolescents to understand the relationship between family functioning and youth psychological maladjustment.


Adaptation, Psychological , Emotional Adjustment , Family Relations/psychology , Adolescent , Emotions , Family Characteristics , Female , Help-Seeking Behavior , Humans , Male , Sex Factors
20.
Psicol. reflex. crit ; 28(3): 454-462, Jul-Sep/2015. tab, graf
Article En | LILACS, INDEXPSI | ID: lil-752002

Anxiety disorders are highly prevalent among school-aged children. These disorders become chronic in a substantial proportion of youths and cause significant interference with daily functioning. The purpose of the current investigation was to examine the psychometric properties of the Portuguese version of the Child Anxiety Life Interference Scale - Parent and Child versions (CALIS-P and CALIS-C). The sample consisted of 132 children between the ages of 7 and 12 with a main diagnosis of anxiety disorder and their parents. A factor analysis of the CALIS-P yielded three factors that agreed with the hypothesised subscales of At Home, Outside Home and Parent Life interference. For the CALIS-C, a factor analysis yielded two factors corresponding to Close Relationships and Performance interference that did not match the subscales of the original version. The internal consistency of the various CALIS subscales was good. Finally, evidence was found for both convergent and divergent validity. The CALIS scores were also significantly correlated with another measure of interference. The results provide initial support that the Portuguese version of the CALIS is a reliable and valid measure for the assessment of the impact of anxiety on child and family functioning.


As perturbações de ansiedade são altamente prevalentes entre crianças em idade escolar. Estas perturbações tendem a seguir um curso crónico e interferem significativamente no funcionamento diário dos jovens. O objetivo principal deste estudo foi examinar as propriedades psicométricas da versão Portuguesa da Escala de Interferência da Ansiedade na Vida da Criança - versões para Pais e Crianças (CALIS-P e CALIS-C). Participaram 132 crianças, com idades entre os 7 e 12 anos, com diagnóstico principal de ansiedade, e seus respetivos pais. A análise fatorial da CALIS-P revelou três fatores que coincidem com as subescalas hipotetizadas: Interferência Em Casa, Fora de Casa e na Vida da Família. Para a CALIS-C, a análise fatorial revelou dois fatores que dizem respeito à Interferência nas Relações Próximas e no Desempenho, que não correspondem às subescalas da versão original. Os estudos psicométricos mostraram uma boa consistência interna para as várias subescalas da CALIS e boas qualidades na validade convergente e divergente. Foi observada ainda uma correlação significativa entre os resultados da CALIS e outra medida de interferência. Estes resultados sugerem que a versão portuguesa da CALIS é uma medida confiável e válida para a avaliação do impacto da ansiedade na criança e no funcionamento familiar.


Humans , Male , Female , Child , Anxiety Disorders/psychology , Surveys and Questionnaires , Reproducibility of Results , Portugal , Psychometrics , Activities of Daily Living/psychology
...