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1.
Biomed Opt Express ; 15(4): 2433-2450, 2024 Apr 01.
Article in English | MEDLINE | ID: mdl-38633075

ABSTRACT

In recent years, imaging photoplethysmograph (iPPG) pulse signals have been widely used in the research of non-contact blood pressure (BP) estimation, in which BP estimation based on pulse features is the main research direction. Pulse features are directly related to the shape of pulse signals while iPPG pulse signals are easily disturbed during the extraction process. To mitigate the impact of pulse feature distortion on BP estimation, it is necessary to eliminate interference while retaining valuable shape details in the iPPG pulse signal. Contact photoplethysmograph (cPPG) pulse signals measured at rest can be considered as the undisturbed reference signal. Transforming the iPPG pulse signal to the corresponding cPPG pulse signal is a method to ensure the effectiveness of shape details. However, achieving the required shape accuracy through direct transformation from iPPG to the corresponding cPPG pulse signals is challenging. We propose a method to mitigate this challenge by replacing the reference signal with an average cardiac cycle (ACC) signal, which can approximately represent the shape information of all cardiac cycles in a short time. A neural network using multi-scale convolution and self-attention mechanisms is developed for this transformation. Our method demonstrates a significant improvement in the maximal information coefficient (MIC) between pulse features and BP values, indicating a stronger correlation. Moreover, pulse signals transformed by our method exhibit enhanced performance in BP estimation using different model types. Experiments are conducted on a real-world database with 491 subjects in the hospital, averaging 60 years of age.

2.
IEEE J Biomed Health Inform ; 28(7): 3928-3941, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38551821

ABSTRACT

Arterial stiffness (AS) serves as a crucial indicator of arterial elasticity and function, typically requiring expensive equipment for detection. Given the strong correlation between AS and various photoplethysmography (PPG) features, PPG emerges as a convenient method for assessing AS. However, the limitations of independent PPG features hinder detection accuracy. This study introduces a feature selection method leveraging the interactive relationships between features to enhance the accuracy of predicting AS from a single-channel PPG signal. Initially, an adaptive signal interception method was employed to capture high-quality signal fragments from PPG sequences. 58 PPG features, deemed to have potential contributions to AS estimation, were extracted and analyzed. Subsequently, the interaction factor (IF) was introduced to redefine the interaction and redundancy between features. A feature selection algorithm (IFFS) based on the IF was then proposed, resulting in a combination of interactive features. Finally, the Xgboost model is utilized to estimate AS from the selected features set. The proposed approach is evaluated on datasets of 268 male and 124 female subjects, respectively. The results of AS estimation indicate that IFFS yields interacting features from numerous sources, rejects redundant ones, and enhances the association. The interaction features combined with the Xgboost model resulted in an MAE of 122.42 and 142.12 cm/sec, an SDE of 88.16 and 102.56 cm/sec, and a PCC of 0.88 and 0.85 for the male and female groups, respectively. The findings of this study suggest that the stated method improves the accuracy of predicting AS from single-channel PPG, which can be used as a non-invasive and cost-effective screening tool for atherosclerosis.


Subject(s)
Algorithms , Photoplethysmography , Signal Processing, Computer-Assisted , Vascular Stiffness , Photoplethysmography/methods , Humans , Male , Female , Vascular Stiffness/physiology , Adult , Young Adult , Middle Aged
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