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1.
Molecules ; 29(8)2024 Apr 19.
Article in English | MEDLINE | ID: mdl-38675676

ABSTRACT

Exploring phytochemicals from ethnomedicinal plants for pharmacological applications is a promising research area. By studying ethnomedicine, researchers can identify plants used for centuries to treat ailments and investigate their phytochemicals. Consequently, phytochemicals can be isolated, characterized, and tested for pharmacological activities, leading to new drug development. This research also helps preserve traditional knowledge and biodiversity. Lithospermum officinale L., found in Eurasia, Argentina (South), Colombia, and the United States, is valued for its medicinal properties, including anti-inflammatory, antioxidant, and antimicrobial effects. The current review emphasizes L. officinale L. as a significant reservoir of bioactive phytochemicals, with alkaloids, quinones, glucosides, phenolics, flavonoids, and lipids identified as the principal metabolites. It also unveils the unexplored potential of this plant for future research endeavors. Continued research on L. officinale L. can unlock its full potential, providing insights into its medicinal uses and contributing to biodiversity preservation.


Subject(s)
Medicine, Traditional , Phytochemicals , Phytochemicals/chemistry , Phytochemicals/pharmacology , Humans , Plant Extracts/chemistry , Plant Extracts/pharmacology , Plants, Medicinal/chemistry , Antioxidants/pharmacology , Antioxidants/chemistry , Anti-Infective Agents/pharmacology , Anti-Infective Agents/chemistry , Anti-Inflammatory Agents/pharmacology , Anti-Inflammatory Agents/chemistry
2.
Molecules ; 29(2)2024 Jan 12.
Article in English | MEDLINE | ID: mdl-38257301

ABSTRACT

Since ancient times, various scientists and doctors have utilized different herbs to heal diseases. Due to the rise in drug resistance and the negative effects of chemosynthetic drugs, researchers and the general public around the world have become more interested in medicinal herbs and plant metabolites/extracts. This is due to its non-toxicity and its several health benefits when used to treat diseases in clinical and medical settings. Ocimum basilicum is one such plant, possessing a wide range of bioactive phytochemicals including alkaloids, phenolics, flavonoids, tannins, saponins, reducing sugars, cardiac glycosides, steroids and glycosides, as well as complex pharmacological activities, including anti-inflammatory, antifungal, antibacterial, antioxidant, wound healing and antiviral properties. The results of many studies on Ocimum basilicum plant extracts are collected and presented in this review. The plant extracts have excellent potential to be used as medicinal raw materials, and exhibit an extensive variety of therapeutic capacities, including antibacterial, antioxidant, wound healing, anti-inflammatory, antifungal, and antiviral properties.


Subject(s)
Anti-Infective Agents , Lamiaceae , Ocimum basilicum , Antifungal Agents , Antioxidants/pharmacology , Anti-Infective Agents/pharmacology , Anti-Bacterial Agents , Plant Extracts/pharmacology , Anti-Inflammatory Agents/pharmacology , Antiviral Agents
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