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1.
NEJM Evid ; 2(10): EVIDstat2300205, 2023 Oct.
Article in English | MEDLINE | ID: mdl-38320183

ABSTRACT

How Censoring WorksA common challenge in clinical research is determining the time to occurrence of a given event. This animated video explores the concept of censoring in survival analysis and how investigators deal with ambiguity in the time of an event's occurrence.

2.
NEJM Evid ; 2(1): EVIDstat2200319, 2023 Jan.
Article in English | MEDLINE | ID: mdl-38320018

ABSTRACT

Of Climate Change and Competing Risks This Stats, STAT! animated video explores the concept of competing risks - and discusses why it is so important for investigators to consider whether the occurrence of one event can prevent or change the likelihood of the occurrence of another.

3.
NEJM Evid ; 2(3): EVIDstat2300007, 2023 Mar.
Article in English | MEDLINE | ID: mdl-38320031

ABSTRACT

Good Intentions to Treat This Stats, STAT! animated video explores common approaches to analyzing data from randomized controlled trials, including intention-to-treat, per-protocol, and as-treated analyses.

4.
NEJM Evid ; 2(12): EVIDstat2300283, 2023 Dec.
Article in English | MEDLINE | ID: mdl-38320503

ABSTRACT

How Statistical Power WorksThis Stats, STAT! animated video explores the concept of statistical power and explains how clinical investigators determine how many participants to enroll in a randomized trial.

5.
NEJM Evid ; 2(5): EVIDstat2300090, 2023 May.
Article in English | MEDLINE | ID: mdl-38320022

ABSTRACT

Bayesian WayThis animated video explores two possible approaches to analyzing data in a randomized controlled trial: "Frequentist" versus "Bayesian."

6.
NEJM Evid ; 2(8): EVIDstat2300128, 2023 Aug.
Article in English | MEDLINE | ID: mdl-38320147

ABSTRACT

Large Language ModelsIn the latest edition of Stats, STAT!, Fralick and colleagues explain the statistics behind large language models - used in chat bots like ChatGPT and Bard. While these new tools may seem remarkably intelligent, at their core they just assemble sentences based on statistics from large amounts of text.

7.
NEJM Evid ; 1(11): EVIDstat2200284, 2022 Nov.
Article in English | MEDLINE | ID: mdl-38319855

ABSTRACT

Blinding is a critical strategy used to limit certain types of bias in randomized controlled trials. This animated video explores the rationale and examines potential threats to keeping group allocation concealed - from study participants and investigators.

8.
NEJM Evid ; 1(9): EVIDstat2200228, 2022 Sep.
Article in English | MEDLINE | ID: mdl-38319791

ABSTRACT

Subgroup Analyses: Subpar or Sublime?This animated video explores some of the potential pitfalls of performing subgroup analyses in randomized controlled trials and explains how to approach potential findings with caution.

9.
NEJM Evid ; 1(7): EVIDstat2200171, 2022 Jul.
Article in English | MEDLINE | ID: mdl-38319259

ABSTRACT

The Problem of Multiple Comparisons This animated video reviews the problem of multiple comparisons in research studies and explains how performing multiple statistical hypothesis tests can produce associations simply by chance.

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