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1.
Semina cienc. biol. saude ; 45(2): 199-210, jul./dez. 2024. tab; ilus
Article in Portuguese | LILACS | ID: biblio-1554831

ABSTRACT

Objetivo: investigar a percepção do peso corporal e as dificuldades encontradas pelas pessoas com deficiência visual na aquisição, na preparação e no consumo dos alimentos. Metodologia: estudo observacional transversal, com adultos e idosos com deficiência visual em Pelotas/RS, realizado no período de abril a maio de 2023. Foi utilizado um questionário composto de 42 itens. Os dados coletados foram analisados por análise descritiva e analítica, e apresentados como média ± desvio padrão ou percentual. Resultados: a amostra contou com 20 pessoas, predominantemente do sexo feminino e idosas. Em relação ao consumo alimentar, 50% dos participantes consomem feijão, 75% frutas e hortaliças, 50% bebidas adoçadas, biscoitos recheados e doces. Referente à percepção do peso corporal, percebeu-se que a maior parte do grupo sente que está acima do peso adequado e se sentem "insatisfeitos(as)". Sobre as dificuldades encontradas, 85% dos participantes relataram dificuldade extrema para identificar a validade dos alimentos, 70% para comprar alimentos frescos e perecíveis e 40% para usar a faca para cortar e descascar os alimentos. Conclusão: verificou-se que a maior parte do grupo sente que está acima do peso adequado e estão "insatisfeitos(as)" em relação ao peso corporal. Além disso, dependem de outra pessoa para escolher os alimentos a serem comprados, saber o prazo de validade, preparar alimentos que precisam ser porcionados, servir refeições no prato, cortar carnes, descascar vegetais e frutas, utilizar faca, entre outros. Esta dependência pode influenciar diretamente no seu consumo alimentar quando essas pessoas se encontram sozinhas, optando por consumir alimentos industrializados de fácil preparo ou prontos.


Objective: to investigate the perception of body weight and the difficulties encountered by people with visual impairments in acquiring, preparing and consuming food. Methodology: cross-sectional observational study, with adults and elderly people with visual impairment in Pelotas/RS, carried out from April to May 2023. A questionnaire composed of 42 items was used. The collected data were analyzed using descriptive and analytical analysis, and presented as mean ± standard deviation or percentage. Results: the sample included 20 people, predominantly female and elderly. Regarding food consumption, 50% of participants consume beans, 75% fruits and vegetables, 50% sweetened drinks, stuffed cookies and sweets. Regarding the perception of body weight, it was noticed that the majority of the group feels that they are overweight and feel "dissatisfied". Regarding the difficulties encountered, 85% of participants reported extreme difficulty in identifying the expiration date of food, 70% in purchasing fresh and perishable foods and 40% in using a knife to cut and peel food. Conclusion: it was found that the majority of the group feels that they are overweight and are "dissatisfied" with their body weight. Furthermore, they depend on someone else to choose the food to be purchased, know the expiration date, prepare food that needs to be portioned, serve meals on the plate, cut meat, peel vegetables and fruits, use a knife, among others. This dependence can directly influence their food consumption when these people are alone, choosing to consume easily prepared or ready-made processed foods.


Subject(s)
Humans , Male , Female
2.
J Int Assoc Provid AIDS Care ; 23: 23259582241281010, 2024.
Article in English | MEDLINE | ID: mdl-39360426

ABSTRACT

Antiretroviral therapy (ART) has improved the survival of people living with HIV (PLHIV) but this success has been accompanied by an increase in noncommunicable diseases. We conducted a prospective cohort study of 4000 adult PLHIV who were initiating ART in Dar es Salaam, Tanzania, to assess weight gain during the first year of treatment and associated sociodemographic and clinical factors. Anthropometric data were collected at ART initiation and monthly follow-up visits. The mean weight gain during the first year of treatment was 2.6 ± 0.3 kg, and the prevalence of overweight or obesity increased from 26.3% at baseline to 40.7%. Female sex, greater household wealth, lower CD4-T-cell counts, higher WHO HIV disease stage, and pulmonary tuberculosis were associated with a greater increase in body mass index (P < .05). Weight gain following ART initiation was common but was greater among females and PLHIV with advanced HIV or comorbidities.


Subject(s)
HIV Infections , Weight Gain , Humans , Female , Tanzania/epidemiology , Male , HIV Infections/drug therapy , HIV Infections/epidemiology , HIV Infections/complications , Adult , Weight Gain/drug effects , Prospective Studies , Middle Aged , Anti-HIV Agents/therapeutic use , Body Mass Index , Young Adult , CD4 Lymphocyte Count , Obesity/epidemiology , Obesity/complications , Urban Population/statistics & numerical data , Anti-Retroviral Agents/therapeutic use , Overweight/epidemiology
3.
Biometals ; 2024 Oct 11.
Article in English | MEDLINE | ID: mdl-39392553

ABSTRACT

Some studies have demonstrated the involvement of high concentrations of copper in the manifestation of insulin resistance in individuals with obesity. The objective of this study was to evaluate the copper nutritional status and its relationship with parameters of glycemic control in women with obesity. An observational case-control clinical study involving 203 women aged between 20 and 50 years, divided into two groups: obese (n = 84) and eutrophic (n = 119). Body weight, height and waist, hip and neck circumferences, dietary copper intake, copper biomarkers, determine ceruloplasmin activity and glycemic control parameters were measured. It was observed that women with obesity had higher copper concentrations in plasma and lower concentrations in erythrocytes when compared to the control group. Analysis of glycemic control parameters revealed a statistically significant difference in fasting blood glucose (p < 0.05) between groups. The study identified a significant positive correlation between plasma copper and fasting insulin values and the Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) index (p < 0.05). The results of this study demonstrate that obese women have high copper concentrations in plasma and lower concentrations in erythrocytes. Furthermore, the significant positive correlation between plasma copper and fasting insulin and HOMA-IR index suggests the influence of this mineral on glycemic control parameters in obese women.

4.
Clin Interv Aging ; 19: 1641-1652, 2024.
Article in English | MEDLINE | ID: mdl-39376978

ABSTRACT

Purpose: This study proposes a multiple mediation model to evaluate the association among diminished physical performance, malnutrition, inflammation, and delirium in seniors with community-acquired pneumonia. Patients and Methods: This retrospective cohort study included elderly patients hospitalized for community-acquired pneumonia at the Geriatrics Department of the Second People's Hospital of Lianyungang from January 1, 2020, to January 1, 2024. Logistic regression analysis was conducted to examine the associations among physical performance, nutritional status, C-reactive protein (CRP) levels, and delirium. Mediation models assessed the effects of nutritional status and CRP on the relationship between physical performance and delirium, with subgroup analyses based on diabetes status. Results: A total of 379 patients were included, with a mean age of 80.0±7.4 years, and 51.7% were male. The incidence of delirium during hospitalization was 28.5% (n=108). Subgroup analyses revealed significant correlations between physical performance, nutritional status, and CRP (P<0.001), regardless of diabetes status. After adjusting for confounding variables, CRP was positively associated with delirium, while MNA-SF and SPPB scores showed negative correlations with delirium risk (OR=0.852, 95% CI: 0.730-0.995; OR=0.580, 95% CI: 0.464-0.727, P<0.05). Mediation analyses indicated that MNA-SF scores and CRP significantly mediated the association between SPPB and delirium. Specifically, pathways "SPPB→ MNA-SF→ delirium", "SPPB→ CRP→ delirium", and "SPPB→ MNA-SF→ CRP→ delirium" demonstrated significant mediating effects in patients without diabetes, while only the pathway "SPPB→ MNA-SF→ CRP→ delirium" was significant in those with diabetes. Conclusion: Older patients with community-acquired pneumonia and poor physical performance are more susceptible to delirium, with nutritional status and inflammation as key mediators.


Subject(s)
C-Reactive Protein , Community-Acquired Infections , Delirium , Inflammation , Nutritional Status , Physical Functional Performance , Pneumonia , Humans , Male , Female , Retrospective Studies , C-Reactive Protein/analysis , Aged , Aged, 80 and over , Geriatric Assessment , Malnutrition , Hospitalization , Logistic Models , Risk Factors
5.
Arch Rehabil Res Clin Transl ; 6(3): 100362, 2024 Sep.
Article in English | MEDLINE | ID: mdl-39372250

ABSTRACT

Objective: To evaluate the relationships between baseline nutritional status, medical events (MEs), and rehabilitation outcomes in individuals undergoing inpatient rehabilitation (IR). Design: A retrospective single center cohort study. Setting: An IR ward. Participants: This study included 409 patients (mean age, 80 years; men, 170 [42%]) undergoing IR for hospital-associated deconditioning, neurologic disorders, or musculoskeletal diseases. Participants were grouped according to the Controlling Nutritional Status score at admission: normal nutrition (NN): 0 to 1, mild malnutrition (MM): 2 to 4, and moderate/severe malnutrition (M/SM): 5 to 12. Interventions: None. Main Outcome Measures: The primary outcomes included MEs leading to death or acute illness requiring transfer to other hospitals for specialized treatments. The secondary outcomes were the rehabilitation efficiency scores (changes in Functional Independence Measure [FIM] score divided by length of stay) for motor function (FIM-M) and cognitive function (FIM-C). Results: Among the 409 participants, 300 (73%) were malnourished at admission. The adjusted hazard ratios (95% confidence interval) for MEs in the MM and M/SM groups relative to the NN group were 1.48 (0.67-3.27) and 0.98 (0.34-2.81), respectively. No significant differences were observed among the 3 groups in FIM-M efficiency scores (mean ± SD, NN: 0.49±0.51 vs MM: 0.41±0.57 vs M/SM: 0.44±1.06, P=.7) or FIM-C efficiency scores (0.04±0.06 vs 0.04±0.06 vs 0.08±0.4, P=0.1). Analysis of covariance showed no significant association between MM or M/SM group and FIM-M efficiency score (beta coefficient = -0.038, P=.6; beta coefficient = 0.15, P=.1, respectively) or FIM-C efficiency score (beta coefficient = 0.004, P=.8; beta coefficient = 0.047, P=.08, respectively). Conclusion: No significant associations were observed between the baseline nutritional status and MEs, FIM-M efficiency score, or FIM-C efficiency score in individuals undergoing IR.

6.
Afr J Reprod Health ; 28(9): 108-121, 2024 Sep 30.
Article in English | MEDLINE | ID: mdl-39372644

ABSTRACT

Stunting, attributed to insufficient nutrition during the critical first 1000 days of life, remains a pressing public health issue in North Sumatera, Indonesia. This study investigates the influence of pre-marital education on prospective couples' knowledge and nutritional status as a stunting prevention strategy. Employing a quantitative, cross-sectional design, the study involved 1000 prospective couples across 10 districts. Data were collected through structured questionnaires and analyzed using Structural Equation Modeling (SEM). The findings demonstrate that pre-marital education significantly enhances knowledge of nutrition, family planning, and stunting prevention, leading to improved nutritional status. However, increased knowledge of stunting was inversely related to nutritional status. The study concludes that comprehensive pre-marital education is vital for effective stunting prevention. It recommends a thorough revision of pre-marital educational content, emphasizing a tailored and integrative approach to health and nutrition, to address specific regional challenges and enhance overall program efficacy.


Le retard de croissance, attribué à une nutrition insuffisante au cours des 1 000 premiers jours critiques de la vie, reste un problème de santé publique urgent dans le nord de Sumatera, en Indonésie. Cette étude examine l'influence de l'éducation prénuptiale sur les connaissances et l'état nutritionnel des futurs couples en tant que stratégie de prévention du retard de croissance. Utilisant une conception quantitative et transversale, l'étude a porté sur 1 000 couples potentiels dans 10 districts. Les données ont été collectées au moyen de questionnaires structurés et analysées à l'aide de la modélisation d'équations structurelles (SEM). Les résultats démontrent que l'éducation prénuptiale améliore considérablement les connaissances en matière de nutrition, de planification familiale et de prévention du retard de croissance, conduisant ainsi à une amélioration de l'état nutritionnel. Cependant, une meilleure connaissance du retard de croissance était inversement liée à l'état nutritionnel. L'étude conclut qu'une éducation prénuptiale complète est essentielle pour une prévention efficace du retard de croissance. Il recommande une révision approfondie du contenu éducatif prénuptial, en mettant l'accent sur une approche adaptée et intégrative de la santé et de la nutrition, pour relever les défis régionaux spécifiques et améliorer l'efficacité globale du programme.


Subject(s)
Growth Disorders , Health Knowledge, Attitudes, Practice , Nutritional Status , Humans , Indonesia/epidemiology , Female , Male , Cross-Sectional Studies , Growth Disorders/prevention & control , Growth Disorders/epidemiology , Adult , Surveys and Questionnaires , Prospective Studies , Health Education/organization & administration , Young Adult
7.
Curr Osteoporos Rep ; 2024 Oct 02.
Article in English | MEDLINE | ID: mdl-39356464

ABSTRACT

How will the scientific community and authoritative bodies define future nutritional requirements for vitamin D? At the International Symposium on Nutritional Aspects of Musculoskeletal Health, the authors debated the strength of current evidence for setting vitamin D intake recommendations from diet: the positive side of the strength of the evidence (PRO) suggests there is a physiological requirement for vitamin D and the opposing view (CON) that in light of negative results from large, recent trials, particularly those with fractures and bone health outcomes, we are left rudderless. Should we provide recommendations based on empiric treatment of vitamin D for most groups and conditions? It is becoming increasingly evident that vitamin D plays a role in many physiological functions and processes associated with long-term human health; however, to what extent are these benefits apparent beyond what is needed for adequate nutritional status, measured as serum 25-hydroxyvitamin D levels, for active calcium absorption? The meeting attendees voted for the PRO vs. CON position at the end of the session.

8.
BMC Surg ; 24(1): 286, 2024 Oct 04.
Article in English | MEDLINE | ID: mdl-39367360

ABSTRACT

BACKGROUND: To assess the efficacy of preoperative halo-gravity traction (HGT) in treating severe spinal deformities, evaluating radiological outcomes, pulmonary function, and nutritional status. METHODS: This study retrospectively included 33 patients with severe spinal deformity who were admitted to our department from April 2018 to January 2022. All the patients underwent HGT prior to the posterior spinal fusion corrective surgery, with no patients having undergone anterior or posterior release procedures. The correction of deformity, pulmonary function tests (PFTs), and nutritional status data were collected and analyzed before and after HGT. RESULTS: A total of 33 patients (9 males, 24 females) were finally included in this study with an average age of 17.79 ± 7.96 (range 12-29) years. Among them, 20 patients were aged ≤ 16 years. The traction weight started from 1.5 kg and raised to 45.2 ± 13.2% of body weight on average progressively, with the average traction duration of 129 ± 63 days. After traction, the main curve was corrected from an average of 120.66 ± 3.89° to 94.88 ± 3.35°, and to 52.33 ± 22.36° (53%) after surgery(P < 0.05). PFTs also showed a significant increase in FVC%, FEV1%, and MEF% after traction [43.46 ± 14.76% vs. 47.33 ± 16.04%, 41.87 ± 13.68% vs. 45.19 ± 15.57%, and 40.44 ± 15.87% vs. 45.24 ± 17.91%, p < 0.05]. Total protein, albumin, and BMI were used as indicators of nutritional status. TP and albumin were significantly improved after traction, from 67.24 ± 5.43 g/L to 70.68 ± 6.98 g/L and 42.40 ± 3.44 g/L 45.72 ± 5.23 g/L, respectively(P < 0.05). No significant difference was found in deformity correction and lung function improvement between patients with traction for more or less than three months (p > 0.05). Two patients developed transient brachial plexus palsy during traction. CONCLUSIONS: Halo-gravity traction can partially correct spinal deformity, enhance pulmonary function. And HGT has been shown to facilitate an improved nutritional status in these patients. It could be used as a preoperative adjuvant treatment for severe spinal deformity. However, according to the study, a traction period longer than three months may not be necessary.


Subject(s)
Nutritional Status , Preoperative Care , Scoliosis , Spinal Fusion , Traction , Humans , Scoliosis/surgery , Male , Female , Traction/methods , Spinal Fusion/methods , Adolescent , Retrospective Studies , Child , Adult , Preoperative Care/methods , Young Adult , Respiratory Function Tests , Treatment Outcome
9.
Rev Esp Geriatr Gerontol ; 60(1): 101558, 2024 Oct 05.
Article in English | MEDLINE | ID: mdl-39369640

ABSTRACT

BACKGROUND: Malnutrition is a prevalent issue among older persons and has been linked to adverse outcomes. Limited information exists regarding its connection with cognition and depression in older persons burdened by chronic diseases, experiencing heightened nutritional and psychosocial vulnerability. In this study, we examined the association between nutritional status, cognitive performance, and depressive symptomatology, in a cohort of older persons with multimorbidity. METHODS: This was a cross-sectional study of 114 pluripathological older persons. Nutritional status was assessed through Mini Nutritional Assessment (MNA), body mass index (BMI) and waist and calf circumferences. Cognition was assessed using Montreal Cognitive Assessment (MoCA) and depressive symptoms were measured with the 15-item Geriatric Depression Scale (GDS-15). RESULTS: MNA score was positively correlated with the MoCA's visuospatial score (rho=0.262) and, participants with normal nutritional status according to MNA, performed better in orientation (p=0.037) and abstraction (p=0.013) domains. MNA was also associated with depressive symptoms, with odds 8.6 times higher in malnourished participants (AOR 8.6, 95% CI 2.6-28.8, p=0.000). Abdominal obesity, meanwhile, was associated with a decrease of 3.33 points in the overall MoCA score (ß -3.33, 95% CI=-5.92; -0.73, p=0.013). CONCLUSION: In older persons with multimorbidity, abdominal obesity and malnutrition were factors associated with lower global and domain-specific cognitive performance and increased depressive symptomatology.

10.
Indian J Tuberc ; 71 Suppl 2: S178-S183, 2024.
Article in English | MEDLINE | ID: mdl-39370180

ABSTRACT

BACKGROUND: Undernutrition is a risk factor for developing tuberculosis (TB) and adherence to treatment leads to successful treatment outcomes. OBJECTIVES: To assess the nutritional status and adherence to treatment among tuberculosis patients in Bhatar Community Development Block of Purba Bardhaman district, West Bengal, India. MATERIAL & METHODS: A cross sectional descriptive study was conducted among all the 82 tuberculosis patients registered between April to June, 2021, under NTEP in Bhatar tuberculosis unit (TU), who completed at least 1 month of therapy. Nutritional status was assessed based on BMI and adherence to treatment was evaluated by interviewing with a validated version of Morisky Medication Adherence Scale (MMAS-8-Item). Data was analysed using SPSS v23. RESULTS: Among the 82 subjects, 51 (62.2%) were found to be underweight and overall high level of adherence to treatment was found among 51 (62.2%) of study subjects. Subjects aged >45 years (AOR 3.686, 95% CI: 1.147-11.842) and having extra-pulmonary Tuberculosis (AOR 8.539, 95% CI: 1.305-55.871) were significantly associated as being adherent to treatment. CONCLUSION: Health education, awareness and more vigilant monitoring is still needed so that TB patients can be cured successfully. Special attention needs to be given on the nutritional status of the TB patients.


Subject(s)
Antitubercular Agents , Medication Adherence , Nutritional Status , Tuberculosis , Humans , India/epidemiology , Male , Female , Antitubercular Agents/therapeutic use , Cross-Sectional Studies , Adult , Middle Aged , Medication Adherence/statistics & numerical data , Tuberculosis/drug therapy , Tuberculosis/epidemiology , Thinness/epidemiology , Tuberculosis, Pulmonary/drug therapy , Tuberculosis, Pulmonary/epidemiology , Young Adult , Malnutrition/epidemiology , Body Mass Index , Adolescent
11.
Article in English | MEDLINE | ID: mdl-39370751

ABSTRACT

BACKGROUND: Undernutrition is a global health concern, particularly in low-income countries, and can manifest as wasting, stunting and/or underweight. In Yemen, the recent armed conflict is likely to have significantly increased the incidence of undernutrition in young children, particularly those living in communities that were already experiencing socioeconomic and health disparities. AIM: To explore the risk factors associated with wasting, stunting and underweight in children aged between six months and five years living in one district of Yemen. METHOD: A cross-sectional study was conducted using a two-part questionnaire to collect anthropometric measurements and sociodemographic characteristics of children enrolled on an outpatient programme for undernourished children at three healthcare facilities in the Jiblah district, and of their families and households. RESULTS: Of the 120 children included in the study, 58 (48%) had wasting, 27 (23%) had stunting and 35 (29%) were underweight. Risk factors for undernutrition included being under the age of three years, being a girl, having had a low birthweight, having siblings under the age of five years, having a mother who is a housewife, living in a household relying on unimproved sources of drinking water, living in a rural area, and living in a low-income household. CONCLUSION: The nutritional status of children in Yemen is under continuing threat. The identification of risk factors for undernutrition may increase awareness of the issue and influence the policy decisions of the international community.

12.
J Nutr Sci ; 13: e43, 2024.
Article in English | MEDLINE | ID: mdl-39351256

ABSTRACT

The aim of this study is to assess nutritional status and associated factors among infants and young children aged 6-23 months in Yeka sub-city, Ethiopia, 2021. An institution-based cross-sectional study was conducted in selected health centres found in the Yeka sub-city from May 2021 to July 2021. In total, 396 systematically selected infants and young children aged 6-23 months attended the selected health centres were included in the study. Data were collected by using a structured questionnaire and anthropometric measurements. A multinomial logistic regression model was used. The overall magnitude of undernutrition and overnutrition among infants and young children were 24.7% and 5.5%, respectively. Dietary diversity score (DDS) ((adjusted odd ratio (AOR) = 5.65; 95% CI = 2.301, 10.87; P value = 0.003), minimum meal frequency (MMF) (AOR = 5.435; 95% CI = 2.097, 11.09; P value = 0.0052), and diarrhoea (AOR = 2.52; 95% CI = 1.007, 6.310; P value = 0.002) were statistically significantly associated factors for nutritional status among infants and young children. Malnutrition (undernutrition and overnutrition) is a public health problem among infants and young children in Yeka sub-city, Ethiopia. DDS, MMF, and diarrhoeal disease were associated with higher odds of undernutrition.


Subject(s)
Malnutrition , Nutritional Status , Humans , Ethiopia/epidemiology , Infant , Cross-Sectional Studies , Female , Male , Malnutrition/epidemiology , Diet , Infant Nutritional Physiological Phenomena , Surveys and Questionnaires , Overnutrition/epidemiology , Diarrhea/epidemiology
13.
JNMA J Nepal Med Assoc ; 62(271): 180-183, 2024 Feb 29.
Article in English | MEDLINE | ID: mdl-39356788

ABSTRACT

INTRODUCTION: The nutritional status of elderly people is crucial for healthy aging, enabling them to maintain productive lives and reduce the progression of chronic diseases. Given that the quality of life tends to decline with age, it becomes particularly crucial for elderly individuals. Therefore, this study was aimed to find out the prevalence of elderly patients at risk of malnutrition in a tertiary hospital. METHODS: This descriptive cross-sectional study was conducted among 281 elderly patients in a tertiary hospital from 2 January 2023 to 10 February 2023 after obtaining ethical approval. Non-probability purposive sampling technique was used. A face-to-face interview was conducted using a structured interview schedule with the elderly in the absence of their caregiver using a standard Mini-Nutritional Assessment tool for nutritional status, and WHOQOL_OLD quality of life for the elderly to assess the quality of life. Point estimate at 95% Confidence Interval was calculated. RESULTS: Out of 281 elderly patients enrolled in our study, 164 (58.36%) (52.64-64.16, 95% Confidence Interval) were at risk of malnutrition. CONCLUSIONS: The study concluded that older people could be at risk of malnutrition, which could impair their quality of life.


Subject(s)
Malnutrition , Nutrition Assessment , Nutritional Status , Quality of Life , Tertiary Care Centers , Humans , Nepal/epidemiology , Cross-Sectional Studies , Female , Malnutrition/epidemiology , Malnutrition/diagnosis , Male , Aged , Middle Aged , Aged, 80 and over , Prevalence , Geriatric Assessment/methods , Risk Factors
14.
Front Pediatr ; 12: 1421155, 2024.
Article in English | MEDLINE | ID: mdl-39355651

ABSTRACT

Aim/Introduction: The relationship between nutritional status upon admission to a pediatric intensive care unit (PICU) and clinical outcomes remains unclear. We examined the relationship between nutrition status, as indicated by body mass index-for-age (BMI-for-age), and clinical outcomes in the PICU. Method: In this retrospective study at a tertiary care center, records of 1,015 critically ill children and adolescents aged one month to 18 years old with available anthropometric parameters were included. The nutritional status upon admission was determined by calculating the BMI-for-age z-score using the WHO growth charts as the reference. The participants were categorized as underweight (BMI-for-age z-score < -2), normal weight (-2 ≤ BMI-for-age z-score ≤ +1), and overweight/obese (BMI-for-age z-score > +1). Multi-variate odds ratios (OR) with 95% confidence intervals (CI) were used to investigate the association between malnutrition (being underweight and overweight/obese) and odds of Prolonged PICU stay (≥7 days) and PICU mortality after controlling for descriptive characteristics, Glasgow Coma Scale score status, fluctuations in serum sodium, and acute kidney injury confounders. Results: The proportions of patients in underweight, normal weight, and overweight/obese categories were 34.2%, 45.8%, and 20%, respectively. During the study period, 21.5% of patients had prolonged PICU stay, and 5.6% of patients in PICU died. Compared to normal-weight patients, underweight patients had higher odds of prolonged PICU stay (OR: 1.52; 95% CI: 1.05-2.22) and PICU mortality (OR: 2.12; 95% CI: 1.22-4.01). Age- and gender-stratified full-adjusted analysis showed that the increased odds of prolonged PICU stay remained significant among underweight boys and underweight individuals aged 5-19 years old. Furthermore, the increased odds of PICU mortality remained significant among underweight individuals aged 2-5 years old. However, being overweight or obese during PICU admission did not demonstrate a significant association with our outcomes in the total sample or subgroup analysis. Conclusion: Our findings showed that PICU patients who were underweight had higher odds of prolonged PICU stay and PICU mortality than their normal-weight counterparts. This underscores the importance of closely monitoring underweight patients in the PICU upon admission in order to improve clinical outcomes.

15.
Nutr Res ; 131: 14-26, 2024 Jul 22.
Article in English | MEDLINE | ID: mdl-39357258

ABSTRACT

Vitamin A deficiency (VAD) remains a major health issue in developing nations, contributing to preventable childhood blindness. However, there is lack of recent data on xerophthalmia, especially among school-aged children in Malaysia. We hypothesized that xerophthalmia persists among rural schoolchildren in Malaysia and potentially associated with socio-demographic status and malnutrition. We conducted a cross-sectional study on 596 schoolchildren (8-12 years) from ten rural primary schools located in five states across Malaysia. Children meeting the criteria for xerophthalmia assessment included those diagnosed with vitamin A deficiency (VAD) (plasma retinol < 0.70 µmol/L) and marginal VAD (plasma retinol 0.70 to < 1.05 µmol/L). The overall prevalence of xerophthalmia was 48.8%, with the most common ocular sign being conjunctival xerosis (38.9%). The occurrence of xerophthalmia was negatively associated with retinol-binding protein 4 (RPB4) (P=0.003), alpha-carotene (P=0.04), hemoglobin (P=0.004), weight (P=0.02), body mass index (BMI) (P=0.04) and WAZ (weight-for-age z-score) (P=0.04) status. Based on multivariate logistic regression analysis, a higher risk of xerophthalmia was observed in boys (Adjusted odd ratio [AOR]: 1.7, 95% confidence interval [CI]: 1.2-2.5) and Orang Asli (OA, indigenous) schoolchildren (AOR: 2.0, 95% CI: 1.3-3.0), while schoolchildren with overweight/obesity status (AOR: 0.5, 95% CI: 0.3-0.8) were associated with a reduced risk of xerophthalmia. The present study unveils a high prevalence of xerophthalmia among vitamin A-deficient primary schoolchildren in rural areas of Malaysia, especially among the indigenous community. The identified socio-demographic and nutritional factors associated to xerophthalmia would facilitate the implementation of more targeted interventions in addressing these issues.

16.
Front Nutr ; 11: 1402307, 2024.
Article in English | MEDLINE | ID: mdl-39360278

ABSTRACT

Background: Increasing evidence suggests that nutrition plays an important role in the treatment of gastric cancer. However, no bibliometrics analysis has been conducted in this field. Our study aimed to conduct a bibliometric study to explore the latest publishing trends and areas of intense activity within the sphere of nutrition in gastric cancer. Method: Publications were extracted from the Web of Science Core Collection. CiteSpace (Version 6.2.4) and VOSviewer (Version 1.6.18) were used for visual analysis. Results: In total, there were 441 publications authored by 2,941 authors from 809 organizations and 47 countries, published in 182 journals from 2013 to 2023. The most prolific country was China, and the most productive institution was the Chinese Academy of Medical Sciences. The leading core journal was Nutrients. P Daisuke Kobayashi and Yasuhiro Kodera were the most influential authors. The first highly cited document was published in Gastric Cancer by Kamarajah et al. The hotspots in this field were nutrition treatment and nutritional status. Moreover, research on nutritional status and nutrition-related prognosis in gastric cancer might be a potential trend. Conclusion: Nutrition in gastric cancer is a burgeoning research field garnering increasing attention. Further investigation is necessary to better understand the impact of nutritional status on the prognosis of gastric cancer.

17.
Am J Clin Nutr ; 120(4): 769-772, 2024 Oct.
Article in English | MEDLINE | ID: mdl-39362728

ABSTRACT

The participants in this debate agreed that: 1) target-based advocacy is required for ensuring countries' engagement and political commitments toward reducing child malnutrition, and the tools used for monitoring progress should be accurate and pose no risk of harmful consequences; and 2) physical growth is not the only dimension of nutritional status to be monitored in clinical and public health practice; anthropometry is thus only one of the diagnostic indicators of nutritional status. Key disagreements included methodological approaches for developing a single growth standard to evaluate nutritional status globally; the relative utility of universal and contextual growth standards for clinical practice and public health; the balance of benefits, harms, and acceptability among stakeholders; and their use as a screening or a definitive tool in individual and public health nutrition. Noteworthy agreements for research priorities included comparison of benefits and harms of using universal compared with contextual growth standards/references and different stakeholders' perception of expectations from and utility of growth standards.


Subject(s)
Consensus , Nutritional Status , Humans , Child, Preschool , Infant , Child Nutrition Disorders/prevention & control , Child Development , Anthropometry , Global Health , Female , Growth Charts , Nutrition Assessment , Male
18.
Support Care Cancer ; 32(10): 697, 2024 Oct 01.
Article in English | MEDLINE | ID: mdl-39352564

ABSTRACT

OBJECTIVE: The study aimed to determine the nutritional status and its prognostic effect on the survival of patients with advanced gastrointestinal cancer. METHODS: A prospective cohort study design was conducted in a tertiary hospital in Shanghai, China. The study consisted of 202 advanced gastrointestinal (GI) cancer patients from a palliative care unit. The following data were collected from the patients: biochemical indicators, i.e., anemia (hemoglobin levels), albumin, pre-albumin, C-reactive protein (CRP), and anthropometric parameters, i.e., body mass index (BMI), nutritional status by Patient-Generated Subjective Global Assessment (PG-SGA), and performance status by Karnofsky Performance Status (KPS). Severe malnutrition was confirmed with the PG-SGA score of ≥ 9. Kaplan-Meier survival analysis and the log-rank test were used to calculate overall survival (OS). The effect of nutritional status on survival was performed by Cox regression analysis. RESULTS: Severe malnutrition was found in 71.3% of patients according to the cutoff of the PG-SGA. PG-SGA score ≥ 9, albumin level < 35 g/L, and CRP level ≥ 10 mg/L predicted shortened life expectancy. Multivariate Cox regression analysis results showed that the PG-SGA score ≥ 9 and the albumin level < 35 g/L were predictive of OS. CONCLUSION: Our data support that severe malnutrition is a predictor for OS in patients with advanced GI cancer. Information on nutritional status should be considered to individualize palliative care plan for these patients, and hence improve their quality of life.


Subject(s)
Gastrointestinal Neoplasms , Malnutrition , Nutritional Status , Palliative Care , Humans , Gastrointestinal Neoplasms/complications , Male , Female , Prospective Studies , Palliative Care/methods , Middle Aged , Prognosis , Aged , Malnutrition/etiology , Malnutrition/epidemiology , China/epidemiology , Proportional Hazards Models , Kaplan-Meier Estimate , Cohort Studies , Karnofsky Performance Status , Adult , Aged, 80 and over , C-Reactive Protein/analysis
19.
Pediatr Gastroenterol Hepatol Nutr ; 27(5): 313-321, 2024 Sep.
Article in English | MEDLINE | ID: mdl-39319278

ABSTRACT

Purpose: For neonates admitted to the neonatal intensive care unit (NICU), appropriate nutritional assessment and intervention are important for adequate growth. In this study, we aimed to determine whether there were changes in the nutritional supply and growth status of premature infants hospitalized in the NICU after the introduction of the Nutrition support team (NST). Methods: This study retrospectively analyzed premature infants admitted to the NICU for over 14 days. The average daily calorie, protein, and fat supply at 1 and 2 weeks after birth were compared before and after NST, and growth was evaluated by changes in length, weight, and head circumference z-scores at birth and 28 days after birth. Results: A total of 79 neonates were included in the present study, with 32 in the pre-NST group and 47 in the post-NST group. The average daily energy supply during the first (p=0.001) and second (p=0.029) weeks postnatal was significantly higher in the post-NST group than in the pre-NST group. Lipid supply for the first week was significantly higher in the post-NST group than in the pre-NST group (p=0.010). The change in the z-score for length was significantly higher in the post-NST group than in the pre-NST group (p=0.049). Conclusion: Nutrient supply and length z-score change increased significantly at 28 days after birth in the post-NST group. These results suggest that calorie calculators and NST activity can promote adequate growth and development in neonates.

20.
J Clin Med ; 13(17)2024 Sep 04.
Article in English | MEDLINE | ID: mdl-39274449

ABSTRACT

Background: Malnutrition harms treatment outcomes, QoL, and survival in lung cancer patients. Effective dietary counseling can improve nutrition, but few randomized controlled trials have focused on lung cancer patients. The objective of this study was to determine if dietary counseling improves nutritional and treatment outcomes when compared to routine care. Methods: This open-label parallel RCT was conducted at Maharaj Nakorn Chiang Mai Hospital in Thailand. The investigators used computer-generated blocked randomization to assign patients to dietary counseling by a nutritionist or routine care. The nutritionist sessions occurred before treatment, with follow-ups at 3-4 weeks and 12 weeks. The primary outcome was the mean percentage change in the body weight of patients at 12 weeks. Secondary outcomes included changes in the BMI, nutrition score, QoL, serum albumin level, lymphocyte count, energy and protein intake, treatment response, PFS, and OS. Results: Between April 2020 and May 2022, after completing recruitment, 80 lung cancer patients were randomized: 43 to dietary counseling and 37 to routine care. The dietary counseling group showed significant benefits, with smaller decreases in body weight at 3-4 weeks (-0.8% vs. -2.6%, p = 0.05) and 12 weeks (-1.1% vs. -4.3%, p = 0.05). They also had higher energy and protein intake levels and better treatment response rates. The secondary outcomes and significant adverse events did not differ significantly between the groups. Conclusions: Dietary counseling helps to maintain body weight, maintain dietary intake, and enhance treatment responses in lung cancer patients. Although not all nutritional markers or survival outcomes were affected, these findings highlight the importance of early nutritional interventions.

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