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1.
Med Sci Monit ; 30: e944692, 2024 Jul 15.
Article in English | MEDLINE | ID: mdl-39004882

ABSTRACT

BACKGROUND Digital dental (DD) technologies need to be developed for dental use because of the prominent position that these technologies have recently acquired. This 21-item online questionnaire-based study aimed to assess the understanding of DD methods in 120 undergraduate dental students at King Faisal University, Saudi Arabia (SA). MATERIAL AND METHODS Electronic surveys were sent to 123 dental students at different study phases (basic, preclinical, and clinical). Dental students were requested to answer the questionnaires in accordance with their knowledge, observations, particular experiences, and DD practice. Data were analyzed using descriptive statistics, which involved numerical values and ratios. Then, the associations among study level, knowledge, practice, and study phases were analyzed using chi-square and Fisher's exact tests. RESULTS Completed questionnaires were returned by 120 students. The chi-square test showed significant differences in relation to questions "Do you have any previous knowledge of DD?", "The field that uses DD the most is…", "Does DD provide more precise results than conventional dentistry?", and "Do you know about CAD/CAM?", with P values of 0.006, 0.000, 0.018, and 0.002, respectively. Students at clinical phase exhibited significantly higher levels of knowledge than those at the preclinical phase (P<0.01). With regard to DD practice, 73.3% of students expressed a negative viewpoint, 82.5% stated that DD is essential for the future, and half said that practicing DD will result in improvements in patient satisfaction, time consumed, and level of predictability. CONCLUSIONS Students at basic, preclinical, and clinical phases had good knowledge on DD and were motivated to practice it in future in their workplaces.


Subject(s)
Students, Dental , Saudi Arabia , Students, Dental/statistics & numerical data , Humans , Surveys and Questionnaires , Male , Female , Education, Dental/methods , Universities , Dentistry/methods , Health Knowledge, Attitudes, Practice , Adult , Young Adult , Digital Technology
2.
Int J Nanomedicine ; 19: 7071-7097, 2024.
Article in English | MEDLINE | ID: mdl-39045343

ABSTRACT

Whiskers are nanoscale, high-strength fibrous crystals with a wide range of potential applications in dentistry owing to their unique mechanical, thermal, electrical, and biological properties. They possess high strength, a high modulus of elasticity and good biocompatibility. Hence, adding these crystals to dental composites as reinforcement can considerably improve the mechanical properties and durability of restorations. Additionally, whiskers are involved in inducing the value-added differentiation of osteoblasts, odontogenic osteocytes, and pulp stem cells, and promoting the regeneration of alveolar bone, periodontal tissue, and pulp tissue. They can also enhance the mucosal barrier function, inhibit the proliferation of tumor cells, control inflammation, and aid in cancer prevention. This review comprehensively summarizes the classification, properties, growth mechanisms and preparation methods of whiskers and focuses on their application in dentistry. Due to their unique physicochemical properties, excellent biological properties, and nanoscale characteristics, whiskers show great potential for application in bone, periodontal, and pulp tissue regeneration. Additionally, they can be used to prevent and treat oral cancer and improve medical devices, thus making them a promising new material in dentistry.


Subject(s)
Dentistry , Humans , Dentistry/methods , Dental Pulp , Biocompatible Materials/chemistry , Animals , Dental Materials/chemistry , Bone Regeneration
3.
Br Dent J ; 237(1): 18, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38997355
5.
Br Dent J ; 237(2): 75, 2024 Jul.
Article in English | MEDLINE | ID: mdl-39060573
6.
Braz Oral Res ; 38: e065, 2024.
Article in English | MEDLINE | ID: mdl-39016371

ABSTRACT

The aim of this review was to map the practice of spin in scientific publications in the dental field. After registering the review protocol (osf.io/kw5qv/), a search was conducted in MEDLINE via PubMed, CENTRAL, Embase, Scopus, LILACS, ClinicalTrials.gov, and OpenGrey databases in June 2023. Any study that evaluated the presence of spin in dentistry was eligible. Data were independently extracted in duplicate by two reviewers. After removing duplicates, 4888 records were screened and 38 were selected for full-text review. Thirteen studies met the eligibility criteria, all of which detected the presence of spin in the primary studies, with the prevalence of spin ranging from 30% to 86%. The most common types of spin assessed in systematic reviews were failure to mention adverse effects of interventions and to report the number of studies/patients contributing to the meta-analysis of main outcomes. In randomized controlled trials, there was a focus on statistically significant within-group and between-group comparisons for primary or secondary outcomes (in abstract results) and claiming equivalence/noninferiority/similarity for statistically nonsignificant results (in abstract conclusions). The practice of spin is widespread in dental scientific literature among different specialties, journals, and countries. Its impact, however, remains poorly investigated.


Subject(s)
Dentistry , Humans , Periodicals as Topic/statistics & numerical data , Dental Research/statistics & numerical data
7.
Acta Odontol Latinoam ; 37(1): 68-78, 2024 04.
Article in English | MEDLINE | ID: mdl-38920128

ABSTRACT

Language disorders may interfere with social integration and affectpersonal development. Beca-use the balance of the stomatognathic system can interfere with language, it is important for speech therapy and dentistry to work together, providing multidisciplinar y Healthcare. AIM: To analyze the 100 most frequently cited articles on language disorders in children and adolescents and assess the interplay with dentistry by means of a bibliometric analysis. MATERIALS AND METHOD: A search of the 100 most frequently cited articles up to December 2021 on language disorders was performed in the Web of Science Core Collection database. Four researchers extracted the data on number of citations, title, authors, country, year of publication, journals, study design, prevalent clinical conditions, and area of expertise. The analyses were performed using VOSviewer and Excel. RESULTS: The total number of citations ranged from 251 to 1,431. Four articles were cited more than 1,000 times. Bishop DVM (10 articles; 3,653 citations) and Tomblin JD (10 articles; 4,261 citations) were the most frequently cited authors. The institutions with the largest number of publications were the University of Oxford/England (11%) and the University of Kansas/USA (8%). Observational study design was the most frequent (77%). Autism spectrum disorder (18%) and dyslexia (14%) were the most broadly investigated clinical conditions. Speech-language pathology (32%) was the area of expertise with the largest number of articles, and none of the top 100 studies showed interplay with dentistry. CONCLUSION: The 100 most widely cited articles on language disorders are mostly observational, mainly address autism spectrum disorder, and are in the field of speech-language pathology No study reported interplay with dentistry.


Os disturbios de linguagem podem interferir na integrando social e afetar o desenvolvimento dos individuos. O trabalho multidisciplinar entre fonoaudiologia e odontologia é muito importante para a promogdo da saúde. O equilibrio do sistema estomatognático interfere na linguagem. OBJETIVO: Analisar os100 artigos mais citados sobre distúrbios de linguagem em criannas e adolescentes e verificar a interando com a odontologia por meio de análise bibliométrica. MATERIAL E MÉTODO: Foi realizada uma busca pelos 100 artigos mais citados sobre distúrbios de linguagem na base de dados Web of Science Core Collection até dezembro de 2021. Quatro pesquisadores extrairam os dados referentes a número de citanoes, titulo, autores, país, ano de publicando, periódicos, desenho de estudo, condinoes clínicas prevalentes e área de especializando. As análises foram realizadas utilizando VOSviewer e Excel. RESULTADOS: O número total de citanoes variou de 251 a 1.431. Quatro artigos foram citados mais de 1.000 vezes. Bishop DVM (10 artigos; 3.653 citanoes) e Tomblin JD (10 artigos; 4.261 citanoes) foram os autores mais frequentemente citados. As instituinoes com maior número de publicanoes foram a Universidade de Oxford/Inglaterra (11%) e a Universidade de Kansas/EUA (8%). O desenho de estudo observacional foi o mais frequente (77%). O transtorno do espectro autista (18%) e a dislexia (14%) foram as condinoes clínicas mais amplamente investigadas. A Fonoaudiologia (32%) foi a área de atuando com maior número de artigos e nenhum estudo, entre os top100, mostrou interando com a Odontologia. CONCLUSÃO: Os 100 artigos mais citados sobre distúrbios de linguagem sdo em sua maioria observacionais, abordam principalmente transtornos do espectro do autismo e estdo na área de fonoaudiologia. Nenhum estudo apresentou interando com a odontologia.


Subject(s)
Bibliometrics , Humans , Child , Adolescent , Language Development Disorders , Dentistry
8.
Cells ; 13(12)2024 Jun 19.
Article in English | MEDLINE | ID: mdl-38920693

ABSTRACT

Bone tissue injuries within oral and dental contexts often present considerable challenges because traditional treatments may not be able to fully restore lost or damaged bone tissue. Novel approaches involving stem cells and targeted 3D scaffolds have been investigated in the search for workable solutions. The use of scaffolds in stem cell-assisted bone regeneration is a crucial component of tissue engineering techniques designed to overcome the drawbacks of traditional bone grafts. This study provides a detailed review of scaffold applications for bone regeneration with stem cells in dentistry. This review focuses on scaffolds and stem cells while covering a broad range of studies explaining bone regeneration in dentistry through the presentation of studies conducted in this field. The role of different stem cells in regenerative medicine is covered in great detail in the reviewed literature. These studies have addressed a wide range of subjects, including the effects of platelet concentrates during dental surgery or specific combinations, such as human dental pulp stem cells with scaffolds for animal model bone regeneration, to promote bone regeneration in animal models. Noting developments, research works consider methods to improve vascularization and explore the use of 3D-printed scaffolds, secretome applications, mesenchymal stem cells, and biomaterials for oral bone tissue regeneration. This thorough assessment outlines possible developments within these crucial regenerative dentistry cycles and provides insights and suggestions for additional study. Furthermore, alternative creative methods for regenerating bone tissue include biophysical stimuli, mechanical stimulation, magnetic field therapy, laser therapy, nutritional supplements and diet, gene therapy, and biomimetic materials. These innovative approaches offer promising avenues for future research and development in the field of bone tissue regeneration in dentistry.


Subject(s)
Bone Regeneration , Dentistry , Stem Cells , Tissue Engineering , Tissue Scaffolds , Humans , Tissue Scaffolds/chemistry , Animals , Stem Cells/cytology , Dentistry/methods , Tissue Engineering/methods , Dental Pulp/cytology , Stem Cell Transplantation/methods , Regenerative Medicine/methods
9.
PLoS One ; 19(6): e0303628, 2024.
Article in English | MEDLINE | ID: mdl-38843230

ABSTRACT

Genes strictly regulate the development of teeth and their surrounding oral structures. Alteration of gene regulation leads to tooth disorders and developmental anomalies in tooth, oral, and facial regions. With the advancement of gene sequencing technology, genomic data is rapidly increasing. However, the large sets of genomic and proteomic data related to tooth development and dental disorders are currently dispersed in many primary databases and literature, making it difficult for users to navigate, extract, study, or analyze. We have curated the scattered genetic data on tooth development and created a knowledgebase called 'Bioinformatics for Dentistry' (https://dentalbioinformatics.com/). This database compiles genomic and proteomic data on human tooth development and developmental anomalies and organizes them according to their roles in different stages of tooth development. The database is built by systemically curating relevant data from the National Library of Medicine (NCBI) GenBank, OMIM: Online Mendelian Inheritance in Man, AlphaFold Protein Structure Database, Reactome pathway knowledgebase, Wiki Pathways, and PubMed. The accuracy of the included data was verified from supporting primary literature. Upon data curation and validation, a simple, easy-to-navigate browser interface was created on WordPress version 6.3.2, with PHP version 8.0. The website is hosted in a cloud hosting service to provide fast and reliable data transfer rate. Plugins are used to ensure the browser's compatibility across different devices. Bioinformatics for Dentistry contains four embedded filters for complex and specific searches and free-text search options for quick and simple searching through the datasets. Bioinformatics for Dentistry is made freely available worldwide, with the hope that this knowledgebase will improve our understanding of the complex genetic regulation of tooth development and will open doors to research initiatives and discoveries. This database will be expanded in the future by incorporating resources and built-in sequence analysis tools, and it will be maintained and updated annually.


Subject(s)
Computational Biology , Databases, Genetic , Tooth , Humans , Computational Biology/methods , Tooth/growth & development , Odontogenesis/genetics , Dentistry , Proteomics/methods , Genomics/methods
10.
Sci Rep ; 14(1): 12630, 2024 06 02.
Article in English | MEDLINE | ID: mdl-38824210

ABSTRACT

In this study, we present the development of a fine structural human phantom designed specifically for applications in dentistry. This research focused on assessing the viability of applying medical computer vision techniques to the task of segmenting individual teeth within a phantom. Using a virtual cone-beam computed tomography (CBCT) system, we generated over 170,000 training datasets. These datasets were produced by varying the elemental densities and tooth sizes within the human phantom, as well as varying the X-ray spectrum, noise intensity, and projection cutoff intensity in the virtual CBCT system. The deep-learning (DL) based tooth segmentation model was trained using the generated datasets. The results demonstrate an agreement with manual contouring when applied to clinical CBCT data. Specifically, the Dice similarity coefficient exceeded 0.87, indicating the robust performance of the developed segmentation model even when virtual imaging was used. The present results show the practical utility of virtual imaging techniques in dentistry and highlight the potential of medical computer vision for enhancing precision and efficiency in dental imaging processes.


Subject(s)
Cone-Beam Computed Tomography , Phantoms, Imaging , Tooth , Humans , Tooth/diagnostic imaging , Tooth/anatomy & histology , Cone-Beam Computed Tomography/methods , Dentistry/methods , Image Processing, Computer-Assisted/methods , Deep Learning
11.
12.
Int J Comput Dent ; 27(2): 135-136, 2024 Jun 06.
Article in English | MEDLINE | ID: mdl-38842260
13.
Comput Biol Med ; 178: 108800, 2024 Aug.
Article in English | MEDLINE | ID: mdl-38917534

ABSTRACT

Computer vision falls under the broad umbrella of artificial intelligence that mimics human vision and plays a vital role in dental imaging. Dental practitioners visualize and interpret teeth, and the structure surrounding the teeth and detect abnormalities by manually examining various dental imaging modalities. Due to the complexity and cognitive difficulty of comprehending medical data, human error makes correct diagnosis difficult. Automated diagnosis may be able to help alleviate delays, hasten practitioners' interpretation of positive cases, and lighten their workload. Several medical imaging modalities like X-rays, CT scans, color images, etc. that are employed in dentistry are briefly described in this survey. Dentists employ dental imaging as a diagnostic tool in several specialties, including orthodontics, endodontics, periodontics, etc. In the discipline of dentistry, computer vision has progressed from classic image processing to machine learning with mathematical approaches and robust deep learning techniques. Here conventional image processing techniques solely as well as in conjunction with intelligent machine learning algorithms, and sophisticated architectures of dental radiograph analysis employ deep learning techniques. This study provides a detailed summary of several tasks, including anatomical segmentation, identification, and categorization of different dental anomalies with their shortfalls as well as future perspectives in this field.


Subject(s)
Image Processing, Computer-Assisted , Humans , Image Processing, Computer-Assisted/methods , Artificial Intelligence , Machine Learning , Tooth/diagnostic imaging , Dentistry/methods , Deep Learning
14.
Ultrason Sonochem ; 108: 106966, 2024 Aug.
Article in English | MEDLINE | ID: mdl-38924854

ABSTRACT

In recent years, researchers have increasingly focused on the development of multiphase trimetallic nanocomposites (TMNC) incorporating ternary metals or metal oxides, which hold significant potential as alternatives for combatting biofilms and bacterial infections. Enhanced oral health is ensured by the innovative techniques used to effectively prevent bacterial adherence and formation of biofilm on dental sutures. In this investigation, TMNC, which consists of Pb, Ag, and Cu, was synthesized using an autoclave-assisted sonochemical technique. Following synthesis, TMNC were characterized using FTIR, XRD, BET, XPS, TGA, and Raman spectroscopy to analyze their shape and microstructure. Subsequent evaluations, including MTT assay, antibacterial activity testing, and biofilm formation analysis, were conducted to assess the efficiency of the synthesized TMNC. Cytotoxicity and anti-human oral squamous cell carcinoma activities of TMNC were evaluated using the Human Oral Cancer cell line (KB) cell line through MTT assay, demonstrating a dose-dependent increase in anti-human oral squamous cell carcinoma activity against the KB cell line compared to the normal cell line, resulting in notably high cell viability. Furthermore, an ultrasonic probe was employed to incorporate TMNC onto dental suturing threads, with different concentrations of TMNC, ultrasonic power levels, and durations considered to determine optimal embedding conditions that result in the highest antibacterial activity. The inhibitory effects of TMNC, both in well diffusion assays and when incorporated into dental suturing threads, against gram-positive (Staphylococcus aureus) and gram-negative (Escherichia coli) bacteria on Mueller-Hinton agar (MHA) were assessed using various concentrations of TMNC. The results of the study indicated that the efficacy of TMNC in inhibiting bacterial growth on dental suturing threads remained impressive, even at low concentrations. Moreover, an evaluation of their potential to destabilize biofilms formed by S. aureus and E. coli, the two pathogens in humans, indicated that TMNC would be a promising anti-biofilm agent.


Subject(s)
Anti-Bacterial Agents , Biofilms , Copper , Lead , Nanocomposites , Silver , Humans , Anti-Bacterial Agents/pharmacology , Anti-Bacterial Agents/chemistry , Anti-Bacterial Agents/chemical synthesis , Nanocomposites/chemistry , Copper/chemistry , Copper/pharmacology , Silver/chemistry , Silver/pharmacology , Biofilms/drug effects , Cell Line, Tumor , Lead/chemistry , Ultrasonic Waves , Dentistry , Cell Survival/drug effects , Chemistry Techniques, Synthetic , Staphylococcus aureus/drug effects , Microbial Sensitivity Tests , Escherichia coli/drug effects
15.
Br Dent J ; 236(11): 892, 2024 06.
Article in English | MEDLINE | ID: mdl-38877258
16.
Compend Contin Educ Dent ; 45(5): 262-265, 2024 May.
Article in English | MEDLINE | ID: mdl-38900466

ABSTRACT

Within the dental industry, it seems as if both dental business owners and clinicians are still attempting to regain footing since the pandemic, unsure of what exactly the future holds. The important thing to note, though, is that even without the pandemic, the dental industry has been and is poised to experience significant and multiple changes simultaneously, some of which will be unprecedented. Today, dentistry is in the midst of seeing these changes take place, and dental professionals are learning how to successfully navigate through them.


Subject(s)
COVID-19 , Humans , COVID-19/prevention & control , Dentistry
17.
Gen Dent ; 72(4): 72-77, 2024.
Article in English | MEDLINE | ID: mdl-38905609

ABSTRACT

This article aims to explore the integration of ChatGPT, an advanced conversational artificial intelligence model, in the field of dentistry. The review primarily consists of information related to the capabilities and functionalities of ChatGPT and how these abilities can aid dental professionals. This study includes data from research papers, case studies, and relevant literature on language models, as well as papers on dentistry, patient communication, dental education, and clinical decision-making. A systematic approach was used to select relevant studies and literature. The selection criteria focused on papers that specifically discussed the integration of language models, ChatGPT in particular, in dentistry and their applications. The study findings revealed that ChatGPT has significant potential to revolutionize dentistry by offering various applications and benefits. It can enhance patient engagement and understanding through personalized oral health information and guidance. In dental education, ChatGPT can provide interactive learning, case studies, and virtual patient simulations. ChatGPT can also assist researchers in analyzing dental literature, identifying patterns, and generating insights. Moreover, it supports dentists with evidence-based recommendations, treatment options, and diagnostic support. Integrating ChatGPT in dentistry can be highly beneficial, but it is crucial to address ethical considerations, accuracy, and privacy concerns. Responsible implementation and continuous improvement of its functionalities are necessary to ensure that patient care and outcomes are improved.


Subject(s)
Artificial Intelligence , Humans , Dentistry/trends , Communication , Education, Dental/trends
18.
Zhonghua Kou Qiang Yi Xue Za Zhi ; 59(6): 531-545, 2024 Jun 09.
Article in Chinese | MEDLINE | ID: mdl-38808413

ABSTRACT

Non fiber-optic transmission technology Er:YAG laser is becoming more widely used in clinical applications, whose therapeutic effects have been recognized by domestic and international researches. However, there is no standardized application for non fiber-optic transmission technology Er:YAG laser in oral medicine. Domestic multidisciplinary dental experts have been organized by Oral Health Branch Association of China Association of Gerontology and Geriatrics to discuss and formulate this standard comprising its application requirements in specialties of dentistry, aiming to promote the standardization of non fiber-optic transmission technology Er:YAG laser clinical use, which could help to better utilize the advantages of laser in oral treatment and to improve the effectiveness of disease treatment.


Subject(s)
Lasers, Solid-State , Lasers, Solid-State/therapeutic use , Humans , Dentistry
19.
JAMA Intern Med ; 184(7): 714-715, 2024 Jul 01.
Article in English | MEDLINE | ID: mdl-38709528
20.
J Dent ; 146: 105058, 2024 07.
Article in English | MEDLINE | ID: mdl-38729286

ABSTRACT

OBJECTIVES: This review aimed to map taxonomy frameworks, descriptions, and applications of immersive technologies in the dental literature. DATA: The Preferred reporting items for systematic reviews and meta-analyses extension for scoping reviews (PRISMA-ScR) guidelines was followed, and the protocol was registered at open science framework platform (https://doi.org/10.17605/OSF.IO/H6N8M). SOURCES: Systematic search was conducted in MEDLINE (via PubMed), Scopus, and Cochrane Library databases, and complemented by manual search. STUDY SELECTION: A total of 84 articles were included, with 81 % between 2019 and 2023. Most studies were experimental (62 %), including education (25 %), protocol feasibility (20 %), in vitro (11 %), and cadaver (6 %). Other study types included clinical report/technique article (24 %), clinical study (9 %), technical note/tip to reader (4 %), and randomized controlled trial (1 %). Three-quarters of the included studies were published in oral and maxillofacial surgery (38 %), dental education (26 %), and implant (12 %) disciplines. Methods of display included head mounted display device (HMD) (55 %), see through screen (32 %), 2D screen display (11 %), and projector display (2 %). Descriptions of immersive realities were fragmented and inconsistent with lack of clear taxonomy framework for the umbrella and the subset terms including virtual reality (VR), augmented reality (AR), mixed reality (MR), augmented virtuality (AV), extended reality, and X reality. CONCLUSIONS: Immersive reality applications in dentistry are gaining popularity with a notable surge in the number of publications in the last 5 years. Ambiguities are apparent in the descriptions of immersive realities. A taxonomy framework based on method of display (full or partial) and reality class (VR, AR, or MR) is proposed. CLINICAL SIGNIFICANCE: Understanding different reality classes can be perplexing due to their blurred boundaries and conceptual overlapping. Immersive technologies offer novel educational and clinical applications. This domain is fast developing. With the current fragmented and inconsistent terminologies, a comprehensive taxonomy framework is necessary.


Subject(s)
Dentistry , Humans , Classification , Education, Dental , Virtual Reality , Augmented Reality
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