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1.
Sci Rep ; 14(1): 12994, 2024 06 06.
Article En | MEDLINE | ID: mdl-38844574

Women frequently express heightened neck discomfort even though they exhibit smaller neck flexion (NF) during smartphone use. Differences in natural posture while using smartphones may result in varying muscle activation patterns between genders. However, no study focused on this issue. This study investigated the influence of gender on neck muscle activity and NF when using smartphones, ranging from slight (20°) to nearly maximal forward head flexion, across different postures. We analyzed smartphone usage patterns in 16 men and 16 women and examined these behaviors across different scenarios: standing, supported sitting, and unsupported sitting, at 20°, 30°, 40°, and the maximum head angles. During data collection, muscle activity was measured, expressed as a percentage of the maximum voluntary contraction (%MVC), in the cervical erector spinae (CES) and upper trapezius (UTZ), along with NF. Results show significant influences of gender, head angle, and posture on all measures, with notable interactions among these variables. Women displayed higher muscle activities in CES and UTZ, yet exhibited lesser NF, while using smartphones in both standing (12.3%MVC, 10.7% MVC, and 69.0°, respectively) and unsupported sitting (10.8%MVC, 12.3%MVC, and 71.8°, respectively) compared to men (standing: 9.5%MVC, 8.8%MVC, and 76.1°; unsupported sitting: 9.7%MVC, 10.8%MVC, and 76.1°). This study provides a potential rationale for gender-related disparities in injury outcomes, emphasizing that women experience higher neck and shoulder discomfort level, despite their smaller NF during smartphone use, as found in previous research. Additionally, the cervical flexion-relaxation phenomenon may occur when the head angle exceeded 40°. The near-maximum head angle during smartphone use might induce the cervical flexion-relaxation phenomenon, potentially aggravating neck issues. We recommend limiting smartphone usage postures that exceed the near-maximum head angle, as they are commonly adopted by individuals in the daily smartphone activities.


Head , Neck Muscles , Posture , Smartphone , Humans , Female , Male , Neck Muscles/physiology , Posture/physiology , Adult , Head/physiology , Young Adult , Neck/physiology , Sex Factors , Electromyography , Sex Characteristics , Neck Pain/physiopathology , Muscle Contraction/physiology , Range of Motion, Articular/physiology
2.
Laryngorhinootologie ; 103(S 01): S125-S147, 2024 May.
Article En, De | MEDLINE | ID: mdl-38697145

Vascular anomalies in the head and neck area are usually rare diseases and pose a particular diagnostic and therapeutic challenge. They are divided into vascular tumours and vascular malformations. A distinction is made between benign tumours, such as infantile haemangioma, and rare malignant tumours, such as angiosarcoma. Vascular malformations are categorised as simple malformations, mixed malformations, large vessel anomalies and those associated with other anomalies. Treatment is interdisciplinary and various modalities are available. These include clinical observation, sclerotherapy, embolisation, ablative and coagulating procedures, surgical resection and systemic drug therapy. Treatment is challenging, as vascular anomalies in the head and neck region practically always affect function and aesthetics. A better understanding of the genetic and molecular biological basis of vascular anomalies has recently led to clinical research into targeted drug therapies. This article provides an up-to-date overview of the diagnosis, clinic and treatment of vascular anomalies in the head and neck region.


Neck , Vascular Malformations , Humans , Vascular Malformations/therapy , Vascular Malformations/diagnosis , Neck/blood supply , Head/blood supply , Sclerotherapy , Interdisciplinary Communication , Combined Modality Therapy , Embolization, Therapeutic , Patient Care Team , Intersectoral Collaboration , Head and Neck Neoplasms/therapy , Head and Neck Neoplasms/diagnosis , Hemangioma/therapy , Hemangioma/diagnosis
3.
Naturwissenschaften ; 111(3): 29, 2024 May 07.
Article En | MEDLINE | ID: mdl-38713269

The vast majority of pterosaurs are characterized by relatively large, elongate heads that are often adorned with large, elaborate crests. Projecting out in front of the body, these large heads and any crests must have had an aerodynamic effect. The working hypothesis of the present study is that these oversized heads were used to control the left-right motions of the body during flight. Using digital models of eight non-pterodactyloids ("rhamphorhyncoids") and ten pterodactyloids, the turning moments associated with the head + neck show a close and consistent correspondence with the rotational inertia of the whole body about a vertical axis in both groups, supporting the idea of a functional relationship. Turning moments come from calculating the lateral area of the head (plus any crests) and determining the associated lift (aerodynamic force) as a function of flight speed, with flight speeds being based on body mass. Rotational inertias were calculated from the three-dimensional mass distribution of the axial body, the limbs, and the flight membranes. The close correlation between turning moment and rotational inertia was used to revise the life restorations of two pterosaurs and to infer relatively lower flight speeds in another two.


Head , Skull , Animals , Biomechanical Phenomena/physiology , Skull/anatomy & histology , Skull/physiology , Head/anatomy & histology , Head/physiology , Flight, Animal/physiology , Dinosaurs/physiology , Dinosaurs/anatomy & histology , Fossils
4.
Sci Data ; 11(1): 436, 2024 May 02.
Article En | MEDLINE | ID: mdl-38698003

During the process of labor, the intrapartum transperineal ultrasound examination serves as a valuable tool, allowing direct observation of the relative positional relationship between the pubic symphysis and fetal head (PSFH). Accurate assessment of fetal head descent and the prediction of the most suitable mode of delivery heavily rely on this relationship. However, achieving an objective and quantitative interpretation of the ultrasound images necessitates precise PSFH segmentation (PSFHS), a task that is both time-consuming and demanding. Integrating the potential of artificial intelligence (AI) in the field of medical ultrasound image segmentation, the development and evaluation of AI-based models rely significantly on access to comprehensive and meticulously annotated datasets. Unfortunately, publicly accessible datasets tailored for PSFHS are notably scarce. Bridging this critical gap, we introduce a PSFHS dataset comprising 1358 images, meticulously annotated at the pixel level. The annotation process adhered to standardized protocols and involved collaboration among medical experts. Remarkably, this dataset stands as the most expansive and comprehensive resource for PSFHS to date.


Artificial Intelligence , Head , Pubic Symphysis , Ultrasonography, Prenatal , Humans , Pubic Symphysis/diagnostic imaging , Female , Pregnancy , Head/diagnostic imaging , Fetus/diagnostic imaging
5.
J Bodyw Mov Ther ; 38: 18-23, 2024 Apr.
Article En | MEDLINE | ID: mdl-38763560

BACKGROUND: Poor posture and sedentary lifestyle cause Forward Head Posture (FHP). To correct this, a Posture Correction Band (PCB) is commonly used. However, the efficacy of PCB vs. McKenzie's Exercises on pulmonary function and chest expansion in asymptomatic individuals with FHP was not known. OBJECTIVE: This study aimed to determine the efficacy of PCB vs. McKenzie's Exercises on the Pulmonary function and chest expansion in asymptomatic population with FHP. METHODOLOGY: A Randomized control trial was conducted on forty-two subjects with FHP. Subjects were divided in two groups. G1 group was educated as per McKenzie's exercises to perform once daily for a month. The Pulmonary function test and chest expansion of this group was performed before and after the McKenzie exercises. G2 group wore PCB for 2 h daily for a month and their PFT and chest expansion was recorded before and after the trial. FVC, FEV1, FEV1/FVC ratio, PEFR and Chest expansion were measured. RESULTS: The P-value of FVC, FEV1, FEV1/FVC ratio and PEFR between the groups (treatment group) was significant as 0.000, 0.000, 0.000 and 0.02 respectively. The chest expansion was non-significant between the groups (treatment group) with P-value as 0.553, 0.493 and 0.699 at axillary, 4th intercostal and xiphisternum level respectively. The P-value of FVC, FEV1, FEV1/FVC ratio and PEFR between the groups (control group) was non-significant as 0.682, 0.149, 0.424 and 0.414 respectively. The chest expansion was also non-significant between the groups (control group) with P-value as 0.853, 0.651 and 0.763 at axillary, 4th intercostal and xiphisternum level. CONCLUSION: The study concluded that there were significant effects of both Posture Correction Band and Mc'Kenzie exercises on pulmonary function with greater difference seen with PCB and non-significant effects on chest expansion in terms of P-values in treatment group.


Posture , Respiratory Function Tests , Humans , Posture/physiology , Male , Female , Adult , Respiratory Function Tests/methods , Exercise Therapy/methods , Thorax/physiology , Lung/physiology , Head/physiology , Young Adult , Middle Aged
6.
Nat Commun ; 15(1): 4154, 2024 May 16.
Article En | MEDLINE | ID: mdl-38755205

The precise neural mechanisms within the brain that contribute to the remarkable lifetime persistence of memory are not fully understood. Two-photon calcium imaging allows the activity of individual cells to be followed across long periods, but conventional approaches require head-fixation, which limits the type of behavior that can be studied. We present a magnetic voluntary head-fixation system that provides stable optical access to the brain during complex behavior. Compared to previous systems that used mechanical restraint, there are no moving parts and animals can engage and disengage entirely at will. This system is failsafe, easy for animals to use and reliable enough to allow long-term experiments to be routinely performed. Animals completed hundreds of trials per session of an odor discrimination task that required 2-4 s fixations. Together with a reflectance fluorescence collection scheme that increases two-photon signal and a transgenic Thy1-GCaMP6f rat line, we are able to reliably image the cellular activity in the hippocampus during behavior over long periods (median 6 months), allowing us track the same neurons over a large fraction of animals' lives (up to 19 months).


Hippocampus , Neurons , Rats, Transgenic , Animals , Hippocampus/cytology , Neurons/metabolism , Rats , Male , Calcium/metabolism , Head/diagnostic imaging , Magnetics , Odorants/analysis , Female
7.
Physiother Res Int ; 29(3): e2093, 2024 Jul.
Article En | MEDLINE | ID: mdl-38780139

OBJECTIVE: Forward head posture (FHP) is a common postural disorder that alters shoulder function. This study examined the efficacy of a corrective program involving postural correction exercises (PCEs), scapular stabilization exercises (SSEs), and kinesiotaping (KT) on improving craniovertebral angle (CVA), scapular position, and dominant hand grip strength (HGS) in individuals with FHP. METHODS: Sixty subjects (8 males and 52 females, 18-40 years old) were randomly allocated into four equal groups: Group A: received PCEs only, Group B: received PCEs and SSEs, Group C: received PCEs and KT, Group D: received PCEs, SSEs and KT. All subjects received treatment for 4 weeks (4 times/week) and postural advice. Outcome measures included cranio-vertebral angle (CVA), scapular position using Lateral Scapular Slide Test and dominant HGS using a CAMRY dynamometer that were assessed at baseline and 4 weeks post intervention. RESULTS: Comparing all groups post training revealed that there were statistically significant increases (p < 0.05) in all measured variables (CVA, scapular position and dominant HGS) in favor of group (D). CONCLUSION: Combination of PCEs, SSEs and KT interventions has achieved the best gains in terms of CVA, dominant HGS and regaining optimal scapular position in FHP subjects.


Hand Strength , Posture , Scapula , Humans , Male , Female , Scapula/physiology , Adult , Posture/physiology , Young Adult , Hand Strength/physiology , Adolescent , Exercise Therapy/methods , Head/physiology , Treatment Outcome
8.
Sci Rep ; 14(1): 11810, 2024 05 23.
Article En | MEDLINE | ID: mdl-38782976

In this retrospective study, we aimed to assess the objective and subjective image quality of different reconstruction techniques and a deep learning-based software on non-contrast head computed tomography (CT) images. In total, 152 adult head CT scans (77 female, 75 male; mean age 69.4 ± 18.3 years) obtained from three different CT scanners using different protocols between March and April 2021 were included. CT images were reconstructed using filtered-back projection (FBP), iterative reconstruction (IR), and post-processed using a deep learning-based algorithm (PS). Post-processing significantly reduced noise in FBP-reconstructed images (up to 15.4% reduction) depending on the protocol, leading to improvements in signal-to-noise ratio of up to 19.7%. However, when deep learning-based post-processing was applied to FBP images compared to IR alone, the differences were inconsistent and partly non-significant, which appeared to be protocol or site specific. Subjective assessments showed no significant overall improvement in image quality for all reconstructions and post-processing. Inter-rater reliability was low and preferences varied. Deep learning-based denoising software improved objective image quality compared to FBP in routine head CT. A significant difference compared to IR was observed for only one protocol. Subjective assessments did not indicate a significant clinical impact in terms of improved subjective image quality, likely due to the low noise levels in full-dose images.


Deep Learning , Head , Software , Tomography, X-Ray Computed , Humans , Female , Tomography, X-Ray Computed/methods , Male , Aged , Head/diagnostic imaging , Retrospective Studies , Middle Aged , Aged, 80 and over , Image Processing, Computer-Assisted/methods , Signal-To-Noise Ratio , Adult , Algorithms , Radiographic Image Interpretation, Computer-Assisted/methods
9.
Sci Rep ; 14(1): 11757, 2024 05 23.
Article En | MEDLINE | ID: mdl-38783000

Chronic imbalance is a frequent and limiting symptom of patients with chronic unilateral and bilateral vestibulopathy. A full-body kinematic analysis of the movement of patients with vestibulopathy would provide a better understanding of the impact of the pathology on dynamic tasks such as walking. Therefore, this study aimed to investigate the global body movement during walking, its variability (assessed with the GaitSD), and the strategies to stabilise the head (assessed with the head Anchoring Index). The full-body motion capture data of 10 patients with bilateral vestibulopathy (BV), 10 patients with unilateral vestibulopathy (UV), and 10 healthy subjects (HS) walking at several speeds (slow, comfortable, and fast) were analysed in this prospective cohort study. We observed only a few significant differences between groups in parts of the gait cycle (shoulder abduction-adduction, pelvis rotation, and hip flexion-extension) during the analysis of kinematic curves. Only BV patients had significantly higher gait variability (GaitSD) for all three walking speeds. Head stabilisation strategies depended on the plan of motion and walking speed condition, but BV and UV patients tended to stabilise their head in relation to the trunk and HS tended to stabilise their head in space. These results suggest that GaitSD could be a relevant biomarker of chronic instability in BV and that the head Anchoring Index tends to confirm clinical observations of abnormal head-trunk dynamics in patients with vestibulopathy while walking.


Bilateral Vestibulopathy , Gait , Head , Walking , Humans , Male , Biomechanical Phenomena , Female , Middle Aged , Walking/physiology , Head/physiopathology , Bilateral Vestibulopathy/physiopathology , Gait/physiology , Adult , Prospective Studies , Aged , Postural Balance/physiology , Chronic Disease
10.
PLoS One ; 19(5): e0299850, 2024.
Article En | MEDLINE | ID: mdl-38787885

Falls in older individuals are a serious health issue in super-aged societies. The stepping reaction is an important postural strategy for preventing falls. This study aimed to reveal the characteristics of lateral stepping in response to mechanical disturbance by means of an analysis of the hip joint kinematics in the stepping leg and head stability during crossover steps. The participants included 11 healthy older and 13 younger individuals. An electromagnet-controlled disturbance-loading device induced crossover steps due to lateral disturbance. Responses were measured using a motion capture system and force plates. The righting reaction of the head was quantified by lateral displacement (sway), neck joint kinematics (angle displacement, angular velocity), and neck joint moment during crossover stepping. Moreover, the relationship between the neck lateral bending moment and angular velocity of hip flexion/adduction of the stepping leg was examined. The lateral head sway was significantly larger in the older participants (1.13±0.7 m/s2) than in the younger individuals (0.54±0.3 m/s2); whereas, the angle displacement (older -14.1±7.1 degree, young -8.3±4.5 degree) and angular velocity (older 9.9±6.6 degree/s, 41.2±27.7 degree/s) of the head were significantly lower in the older than in the younger participants. In both groups, the moment of neck lateral bending exhibited a significant negative correlation with the hip flexion angular velocity of the stepping leg. Correlation analysis also showed a significant negative correlation between the neck lateral bending moment and hip adduction angular velocity only in the older group (r = 0.71, p<0.01). In conclusion, older individuals increased instability in the lateral direction of the head and decreased righting angle displacement and angular velocity of the head during crossover steps. The correlation between neck moment and hip flexion/adduction angular velocity suggested a decrease in step speed due to increased neck muscle tone, which could be influenced by vestibulospinal reflexes.


Aging , Head , Hip Joint , Humans , Biomechanical Phenomena , Hip Joint/physiology , Male , Aged , Female , Aging/physiology , Head/physiology , Adult , Postural Balance/physiology , Young Adult , Accidental Falls/prevention & control , Walking/physiology
12.
Nat Commun ; 15(1): 4550, 2024 May 29.
Article En | MEDLINE | ID: mdl-38811547

The emergence of new structures can often be linked to the evolution of novel cell types that follows the rewiring of developmental gene regulatory subnetworks. Vertebrates are characterized by a complex body plan compared to the other chordate clades and the question remains of whether and how the emergence of vertebrate morphological innovations can be related to the appearance of new embryonic cell populations. We previously proposed, by studying mesoderm development in the cephalochordate amphioxus, a scenario for the evolution of the vertebrate head mesoderm. To further test this scenario at the cell population level, we used scRNA-seq to construct a cell atlas of the amphioxus neurula, stage at which the main mesodermal compartments are specified. Our data allowed us to validate the presence of a prechordal-plate like territory in amphioxus. Additionally, the transcriptomic profile of somite cell populations supports the homology between specific territories of amphioxus somites and vertebrate cranial/pharyngeal and lateral plate mesoderm. Finally, our work provides evidence that the appearance of the specific mesodermal structures of the vertebrate head was associated to both segregation of pre-existing cell populations, and co-option of new genes for the control of myogenesis.


Gene Expression Regulation, Developmental , Head , Lancelets , Mesoderm , Vertebrates , Animals , Mesoderm/cytology , Mesoderm/embryology , Lancelets/embryology , Lancelets/genetics , Head/embryology , Vertebrates/embryology , Vertebrates/genetics , Somites/embryology , Somites/cytology , Somites/metabolism , Biological Evolution , Transcriptome
13.
BMC Med Educ ; 24(1): 531, 2024 May 14.
Article En | MEDLINE | ID: mdl-38741079

BACKGROUND: An urgent need exists for innovative surgical video recording techniques in head and neck reconstructive surgeries, particularly in low- and middle-income countries where a surge in surgical procedures necessitates more skilled surgeons. This demand, significantly intensified by the COVID-19 pandemic, highlights the critical role of surgical videos in medical education. We aimed to identify a straightforward, high-quality approach to recording surgical videos at a low economic cost in the operating room, thereby contributing to enhanced patient care. METHODS: The recording was comprised of six head and neck flap harvesting surgeries using GoPro or two types of digital cameras. Data were extracted from the recorded videos and their subsequent editing process. Some of the participants were subsequently interviewed. RESULTS: Both cameras, set at 4 K resolution and 30 frames per second (fps), produced satisfactory results. The GoPro, worn on the surgeon's head, moves in sync with the surgeon, offering a unique first-person perspective of the operation without needing an additional assistant. Though cost-effective and efficient, it lacks a zoom feature essential for close-up views. In contrast, while requiring occasional repositioning, the digital camera captures finer anatomical details due to its superior image quality and zoom capabilities. CONCLUSION: Merging these two systems could significantly advance the field of surgical video recording. This innovation holds promise for enhancing technical communication and bolstering video-based medical education, potentially addressing the global shortage of specialized surgeons.


COVID-19 , Video Recording , Humans , COVID-19/epidemiology , Plastic Surgery Procedures/education , Surgical Flaps , SARS-CoV-2 , Head/surgery , Neck/surgery
14.
BMC Musculoskelet Disord ; 25(1): 376, 2024 May 13.
Article En | MEDLINE | ID: mdl-38741076

OBJECTIVES: The traditional understanding of craniocervical alignment emphasizes specific anatomical landmarks. However, recent research has challenged the reliance on forward head posture as the primary diagnostic criterion for neck pain. An advanced relationship exists between neck pain and craniocervical alignment, which requires a deeper exploration of diverse postures and movement patterns using advanced techniques, such as clustering analysis. We aimed to explore the complex relationship between craniocervical alignment, and neck pain and to categorize alignment patterns in individuals with nonspecific neck pain using the K-means algorithm. METHODS: This study included 229 office workers with nonspecific neck pain who applied unsupervised machine learning techniques. The craniocervical angles (CCA) during rest, protraction, and retraction were measured using two-dimensional video analysis, and neck pain severity was assessed using the Northwick Park Neck Pain Questionnaire (NPQ). CCA during sitting upright in a comfortable position was assessed to evaluate the resting CCA. The average of midpoints between repeated protraction and retraction measures was considered as the midpoint CCA. The K-means algorithm helped categorize participants into alignment clusters based on age, sex and CCA data. RESULTS: We found no significant correlation between NPQ scores and CCA data, challenging the traditional understanding of neck pain and alignment. We observed a significant difference in age (F = 140.14, p < 0.001), NPQ total score (F = 115.83, p < 0.001), resting CCA (F = 79.22, p < 0.001), CCA during protraction (F = 33.98, p < 0.001), CCA during retraction (F = 40.40, p < 0.001), and midpoint CCA (F = 66.92, p < 0.001) among the three clusters and healthy controls. Cluster 1 was characterized by the lowest resting and midpoint CCA, and CCA during pro- and -retraction, indicating a significant forward head posture and a pattern of retraction restriction. Cluster 2, the oldest group, showed CCA measurements similar to healthy controls, yet reported the highest NPQ scores. Cluster 3 exhibited the highest CCA during protraction and retraction, suggesting a limitation in protraction movement. DISCUSSION: Analyzing 229 office workers, three distinct alignment patterns were identified, each with unique postural characteristics; therefore, treatments addressing posture should be individualized and not generalized across the population.


Neck Pain , Posture , Unsupervised Machine Learning , Humans , Neck Pain/physiopathology , Male , Female , Adult , Posture/physiology , Middle Aged , Cluster Analysis , Head , Cervical Vertebrae/physiopathology , Cervical Vertebrae/diagnostic imaging , Movement/physiology , Pain Measurement/methods , Young Adult , Head Movements/physiology
15.
Comput Biol Med ; 175: 108501, 2024 Jun.
Article En | MEDLINE | ID: mdl-38703545

The segmentation of the fetal head (FH) and pubic symphysis (PS) from intrapartum ultrasound images plays a pivotal role in monitoring labor progression and informing crucial clinical decisions. Achieving real-time segmentation with high accuracy on systems with limited hardware capabilities presents significant challenges. To address these challenges, we propose the real-time segmentation network (RTSeg-Net), a groundbreaking lightweight deep learning model that incorporates innovative distribution shifting convolutional blocks, tokenized multilayer perceptron blocks, and efficient feature fusion blocks. Designed for optimal computational efficiency, RTSeg-Net minimizes resource demand while significantly enhancing segmentation performance. Our comprehensive evaluation on two distinct intrapartum ultrasound image datasets reveals that RTSeg-Net achieves segmentation accuracy on par with more complex state-of-the-art networks, utilizing merely 1.86 M parameters-just 6 % of their hyperparameters-and operating seven times faster, achieving a remarkable rate of 31.13 frames per second on a Jetson Nano, a device known for its limited computing capacity. These achievements underscore RTSeg-Net's potential to provide accurate, real-time segmentation on low-power devices, broadening the scope for its application across various stages of labor. By facilitating real-time, accurate ultrasound image analysis on portable, low-cost devices, RTSeg-Net promises to revolutionize intrapartum monitoring, making sophisticated diagnostic tools accessible to a wider range of healthcare settings.


Head , Pubic Symphysis , Ultrasonography, Prenatal , Humans , Female , Pregnancy , Head/diagnostic imaging , Ultrasonography, Prenatal/methods , Pubic Symphysis/diagnostic imaging , Deep Learning , Fetus/diagnostic imaging
16.
F1000Res ; 13: 274, 2024.
Article En | MEDLINE | ID: mdl-38725640

Background: The most recent advances in Computed Tomography (CT) image reconstruction technology are Deep learning image reconstruction (DLIR) algorithms. Due to drawbacks in Iterative reconstruction (IR) techniques such as negative image texture and nonlinear spatial resolutions, DLIRs are gradually replacing them. However, the potential use of DLIR in Head and Chest CT has to be examined further. Hence, the purpose of the study is to review the influence of DLIR on Radiation dose (RD), Image noise (IN), and outcomes of the studies compared with IR and FBP in Head and Chest CT examinations. Methods: We performed a detailed search in PubMed, Scopus, Web of Science, Cochrane Library, and Embase to find the articles reported using DLIR for Head and Chest CT examinations between 2017 to 2023. Data were retrieved from the short-listed studies using Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines. Results: Out of 196 articles searched, 15 articles were included. A total of 1292 sample size was included. 14 articles were rated as high and 1 article as moderate quality. All studies compared DLIR to IR techniques. 5 studies compared DLIR with IR and FBP. The review showed that DLIR improved IQ, and reduced RD and IN for CT Head and Chest examinations. Conclusions: DLIR algorithm have demonstrated a noted enhancement in IQ with reduced IN for CT Head and Chest examinations at lower dose compared with IR and FBP. DLIR showed potential for enhancing patient care by reducing radiation risks and increasing diagnostic accuracy.


Algorithms , Deep Learning , Head , Radiation Dosage , Tomography, X-Ray Computed , Humans , Tomography, X-Ray Computed/methods , Head/diagnostic imaging , Image Processing, Computer-Assisted/methods , Thorax/diagnostic imaging , Radiography, Thoracic/methods , Signal-To-Noise Ratio
18.
Elife ; 132024 May 30.
Article En | MEDLINE | ID: mdl-38814703

To navigate their environment, insects need to keep track of their orientation. Previous work has shown that insects encode their head direction as a sinusoidal activity pattern around a ring of neurons arranged in an eight-column structure. However, it is unclear whether this sinusoidal encoding of head direction is just an evolutionary coincidence or if it offers a particular functional advantage. To address this question, we establish the basic mathematical requirements for direction encoding and show that it can be performed by many circuits, all with different activity patterns. Among these activity patterns, we prove that the sinusoidal one is the most noise-resilient, but only when coupled with a sinusoidal connectivity pattern between the encoding neurons. We compare this predicted optimal connectivity pattern with anatomical data from the head direction circuits of the locust and the fruit fly, finding that our theory agrees with experimental evidence. Furthermore, we demonstrate that our predicted circuit can emerge using Hebbian plasticity, implying that the neural connectivity does not need to be explicitly encoded in the genetic program of the insect but rather can emerge during development. Finally, we illustrate that in our theory, the consistent presence of the eight-column organisation of head direction circuits across multiple insect species is not a chance artefact but instead can be explained by basic evolutionary principles.


Insects, including fruit flies and locusts, move throughout their environment to find food, interact with each other or escape danger. To navigate their surroundings, insects need to be able to keep track of their orientation. This tracking is achieved through visual cues and integrating information about their movements whilst flying so they know which direction their head is facing. The set of neurons responsible for relaying information about the direction of the head (also known as heading) are connected together in a ring made up of eight columns of cells. Previous studies showed that the level of activity across this ring of neurons resembles a sinusoid shape: a smooth curve with one peak which encodes the animal's heading. Neurons downstream from this eight-column ring, which relay velocity information, also display this sinusoidal pattern of activation. Aceituno, Dall'Osto and Pisokas wanted to understand whether this sinusoidal pattern was an evolutionary coincidence, or whether it offers a particular advantage to insects. To answer this question, they established the mathematical criteria required for neurons in the eight-column ring to encode information about the heading of the animal. This revealed that these conditions can be satisfied by many different patterns of activation, not just the sinusoidal shape. However, Aceituno, Dall'Osto and Pisokas show that the sinusoidal shape is the most resilient to variations in neuronal activity which may impact the encoded information. Further experiments revealed that this resilience only occurred if neurons in the circuit were connected together in a certain pattern. Aceituno, Dall'Osto and Pisokas then compared this circuit with experimental data from locusts and fruit flies and found that both insects exhibit the predicted connection pattern. They also discovered that animals do not have to be born with this neuronal connection pattern, but can develop it during their lifetime. These findings provide fresh insights into how insects relay information about the direction of their head as they fly. They suggest that the structure of the neuronal circuit responsible for encoding head direction was not formed by chance but instead arose due to the evolutionary benefits it provided.


Head , Animals , Head/physiology , Grasshoppers/physiology , Neurons/physiology , Insecta/physiology , Models, Neurological , Drosophila melanogaster/physiology
19.
PLoS One ; 19(5): e0304040, 2024.
Article En | MEDLINE | ID: mdl-38814896

This study investigates head nods in natural dyadic German Sign Language (DGS) interaction, with the aim of finding whether head nods serving different functions vary in their phonetic characteristics. Earlier research on spoken and sign language interaction has revealed that head nods vary in the form of the movement. However, most claims about the phonetic properties of head nods have been based on manual annotation without reference to naturalistic text types and the head nods produced by the addressee have been largely ignored. There is a lack of detailed information about the phonetic properties of the addressee's head nods and their interaction with manual cues in DGS as well as in other sign languages, and the existence of a form-function relationship of head nods remains uncertain. We hypothesize that head nods functioning in the context of affirmation differ from those signaling feedback in their form and the co-occurrence with manual items. To test the hypothesis, we apply OpenPose, a computer vision toolkit, to extract head nod measurements from video recordings and examine head nods in terms of their duration, amplitude and velocity. We describe the basic phonetic properties of head nods in DGS and their interaction with manual items in naturalistic corpus data. Our results show that phonetic properties of affirmative nods differ from those of feedback nods. Feedback nods appear to be on average slower in production and smaller in amplitude than affirmation nods, and they are commonly produced without a co-occurring manual element. We attribute the variations in phonetic properties to the distinct roles these cues fulfill in turn-taking system. This research underlines the importance of non-manual cues in shaping the turn-taking system of sign languages, establishing the links between such research fields as sign language linguistics, conversational analysis, quantitative linguistics and computer vision.


Phonetics , Sign Language , Humans , Germany , Male , Head/physiology , Female , Language , Head Movements/physiology
20.
Sci Data ; 11(1): 538, 2024 May 25.
Article En | MEDLINE | ID: mdl-38796526

Mixed reality navigation (MRN) technology is emerging as an increasingly significant and interesting topic in neurosurgery. MRN enables neurosurgeons to "see through" the head with an interactive, hybrid visualization environment that merges virtual- and physical-world elements. Offering immersive, intuitive, and reliable guidance for preoperative and intraoperative intervention of intracranial lesions, MRN showcases its potential as an economically efficient and user-friendly alternative to standard neuronavigation systems. However, the clinical research and development of MRN systems present challenges: recruiting a sufficient number of patients within a limited timeframe is difficult, and acquiring low-cost, commercially available, medically significant head phantoms is equally challenging. To accelerate the development of novel MRN systems and surmount these obstacles, the study presents a dataset designed for MRN system development and testing in neurosurgery. It includes CT and MRI data from 19 patients with intracranial lesions and derived 3D models of anatomical structures and validation references. The models are available in Wavefront object (OBJ) and Stereolithography (STL) formats, supporting the creation and assessment of neurosurgical MRN applications.


Neuronavigation , Humans , Neurosurgical Procedures , Magnetic Resonance Imaging , Head/surgery , Tomography, X-Ray Computed , Imaging, Three-Dimensional
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