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1.
Gac Med Mex ; 152 Suppl 1: 67-73, 2016 Sep.
Article in Spanish | MEDLINE | ID: mdl-27603891

ABSTRACT

The most common problem limiting milk consumption worldwide is lactose intolerance (LI), which is defined as the experience of gastrointestinal symptoms due to the intake of lactose-containing food. When symptoms ensue the intake of milk, the condition is referred as milk intolerance, and it may or may not be due to LI. The most common cause of LI is primary lactase deficiency which occurs in 30% of Mexican adults when one glass of milk is consumed (12-18 g of lactose). LI occurs in less than 15% of adults after the intake of this dose of lactose. Another cause of lactose intolerance is due to secondary lactase deficiency, which occurs because lactase is reduced due to diseases that affect the intestinal mucosa. Lactose intolerance can be eliminated or significantly reduced by elimination or reduction of the intake of milk and milk containing products. Recent studies demonstrate that when ß-casein-A1 contained in milk is hydrolyzed it produces ß-casomorphine-7 which is an opioid associated with milk intolerance.


Subject(s)
Lactase/deficiency , Lactose Intolerance/etiology , Milk/adverse effects , Animals , Caseins/adverse effects , Humans , Lactose/adverse effects , Lactose Intolerance/epidemiology , Lactose Intolerance/therapy , Mexico/epidemiology , Milk/chemistry
2.
Rev. Odontol. Araçatuba (Impr.) ; 37(1): 46-52, jan.-abr. 2016. tab
Article in Portuguese | BBO - Dentistry | ID: biblio-857031

ABSTRACT

A lactose é um dissacarídeo hidrolisado pela enzima lactase, que libera seus componentes monossacarídeos para absorção na corrente sanguínea. Na falta dessa enzima, a lactose é fermentada no cólon causando desconforto abdominal. O seu tratamento é evitar o consumo de produtos ricos em lactose ou ingerir a enzima lactase com os produtos lácteos ou, ainda, dar preferência a produtos que a lactose tenha sido removida pela fermentação. Porém, essa redução no consumo de leite e seus derivados podem comprometer a absorção de proteínas e cálcio. O presente estudo tem como objetivo realizar uma atualização sobre a intolerância a lactose, com ênfase na epidemiologia e principais tratamentos, em especial o tratamento nutricional que visa prevenir possíveis carências nutricionais. Foi realizada uma pesquisa bibliográfica a partir de artigos nacionais e internacionais publicados junto ao banco de dados PubMed, SciELO e Google Acadêmico, utilizando-se as seguintes palavras-chave: Deficiência de Lactase, Epidemiologia, Intolerância à Lactose e Lactose. Foram selecionadas publicações datadas do ano de 2002 a 2014, sendo os artigos agrupados por assunto e selecionados conforme a qualidade e relevância com o tema proposto. Ao término dessa pesquisa, concluiu-se que a intolerância à lactose afeta muitas pessoas mundialmente, ocasionando uma baixa ingestão de cálcio. As pessoas que possuem o distúrbio devem buscar outros tipos de alimentos fontes desse mineral, pois a sua deficiência pode acarretar em prejuízos a saúde, em especial do tecido ósseo


Lactose is a disaccharide hydrolyzed by lactase enzyme that releases its monosaccharide components for absorption into the bloodstream. In the absence of this enzyme, lactose is fermented in the colon causing abdominal discomfort. The treatment is avoiding consumption of products rich in lactose or ingesting the enzyme lactase to milk products, or even to prefer products that lactose has been removed by fermentation. However, this reduction in the consumption of milk and dairy products may compromise the absorption of protein and calcium. This study aims to perform an update on lactose intolerance, with emphasis on epidemiology and major treatments, especially nutritional treatment that aims to prevent possible nutritional deficiencies. a literature search was conducted from national and international articles published by the PubMed database, SciELO and Google Scholar, using the following keywords: Deficiency Lactase, Epidemiology, Lactose intolerance and lactose. dated publications were selected from the year 2002 to 2014, and the articles grouped by subject and selected according to the quality and relevance to the theme. At the end of this research, it was concluded that lactose intolerance affects many people worldwide, causing a low calcium intake. People with the disorder should seek other sources of zinc because its deficiency can result in damage to health, especially of bone tissue


Subject(s)
Calcium Deficiency , Lactose Intolerance , Lactose Intolerance/epidemiology , Lactose Intolerance/therapy , Lactose
3.
Comun. ciênc. saúde ; 25(3/4): 291-302, nov. 27, 2014. ilus
Article in Portuguese | LILACS | ID: biblio-997124

ABSTRACT

INTRODUÇÃO: A alergia ao leite de vaca é caracterizada por reações imunológicas adversas, imediatas ou não, decorrentes do contato com a proteína do leite de vaca. OBJETIVO: Avaliar o estado nutricional e o consumo calórico-proteico de portadora de Alergia à Leite de Vaca. Metodologia: Estudo de caso realizado com escolar de 3 anos com alergia. Foi avaliado a antropometria, o consumo alimentar de calorias e proteínas pelo registro de 3 dias , antes e após a remissão dos sintomas e o uso de fórmulas para fins especiais. As informações foram comparadas com padrões de referência para consumo alimentar e protocolos de tratamento para alergia. RESULTADOS E DISCUSSÃO: Paciente com histórico de baixo peso ao nascimento. Ao longo do crescimento e desenvolvimento apresentou períodos de estagnação, baixo peso e risco nutricional devido à intercorrências como alergia, crises respiratórias e vômitos. Foi necessária intervenção clínica e nutricional com fórmulas especializadas e dieta especial. Aos 2 anos e 9 meses adquiriu espontaneamente a tolerância à proteína do leite e passou a consumir leite e derivados sem a presença de sintomas, no entanto, manteve a baixa estatura e peso para idade, mesmo ingerindo todos os grupos alimentares o que mostra a importância do acompanhamento nutricional , mesmo após cessado o agravo. CONCLUSÃO: A forma de tratamento da alergia ao leite de vaca é por meio da alimentação, com uma dieta substitutiva adequada e acompanhamento nutricional. É fundamental o acompanhamento da antropometria, o consumo calórico e proteico durante o tratamento, assim como a história do nascimento, para se evitar o comprometimento do crescimento e desenvolvimento.


INTRODUCTION: Allergy to cow's milk is characterized by harsh, immediate or otherwise, arising from contact with immune reactions to cow's milk protein. OBJECTIVE: To assess the nutritional status and calorie-protein intake carrier Allergy to Cow's Milk. METHODOLOGY: Case study done with three year-old child with allergy. Anthropometry, dietary intake of calories and protein for registering 3 days before and after remission of symptoms and the use of formulas for special purposes was evaluated. The results were compared with reference standards for food consumption and for allergy treatment protocols. RESULTS AND DISCUSSION: Patient with a history of low birth weight. Throughout the growth and development showed periods of stagnation, low weight and nutritional risk due to complications such as allergies, respiratory crises and vomiting. Was necessary clinical and nutritional intervention with specialized formulas and special diet. Since her two years and nine months, she spontaneously acquired tolerance to milk protein and proceeded to consume dairy products without the presence of symptoms, however, remained low height for age and weight, even eating all the food groups which shows the importance nutritional monitoring, ceased even after the grievance. CONCLUSION: The treatment of allergy to cow's milk is through food, with adequate replacement diet and nutritional counseling. It is critical monitoring of anthropometry, caloric and protein intake during treatment, as well as the story of the birth, to avoid compromising growth and development.


Subject(s)
Humans , Infant , Eating , Anthropometry , Milk Hypersensitivity , Milk Hypersensitivity/diagnosis , Hypersensitivity , Therapeutics , Nutritional Status , Child Nutrition , Lactose Intolerance/diagnosis , Lactose Intolerance/therapy
4.
Rev. pediatr. electrón ; 8(3)dic. 2011. tab
Article in Spanish | LILACS | ID: lil-673041

ABSTRACT

La lactosa es un disacárido de amplia distribución en la dieta y productos farmacéuticos, es el hidrato de carbono de la leche de los mamíferos. La intolerancia a la lactosa puede presentarse como congénita, hipolactasia del desarrollo, primaria y secundaria. Frente a la sospecha de ésta patología la clínica es lo principal, pudiendo investigarla a través de la prueba contraprueba, la prueba de hidrógeno espirado, la biopsia y por estudio de polimorfismos a través biología molecular (aún en estudio). Su tratamiento consiste en la disminución o exclusión de lactosa, uso de suplementos lácteos, sin olvidar la ingesta mínima requerida de calcio y vitamina D importantes en el desarrollo óseo.


Subject(s)
Humans , Lactose Intolerance/diagnosis , Lactose Intolerance/therapy , Lactose Intolerance/classification , Lactose Intolerance/physiopathology , Lactose Tolerance Test
5.
Rev Assoc Med Bras (1992) ; 56(2): 230-6, 2010.
Article in Portuguese | MEDLINE | ID: mdl-20499001

ABSTRACT

In most mammals, lactase activity declines on the intestinal wall after weaning, characterizing primary hypolactasia that provokes symptoms of lactose intolerance. The intensity of symptoms of distention, flatulence, abdominal pain and diarrhea varies, according to the amount of ingested lactose, and increases with age. Hypolactasia is genetically determined; nonetheless, a mutation occurred that had made a part of mankind tolerate milk in adulthood. Diagnosis is made by a tolerance test, using the lactose challenge. With the discovery made by the Finns of polymorphism associated with lactase persistence, mainly, in Northern Europe, the genetic test was incorporated as a more comfortable diagnostic tool for the intolerant. In Brazil, 43% of Caucasian and Mulatto groups have lactase persistence allele, with hipolactasia more frequently found among Blacks and Japanese. However, in clinical practice people with hypolactasia may be advised to consume certain dairy products and food containing lactose without developing intolerance symptoms, whereas others will need a lactose restriction diet.


Subject(s)
Lactose Intolerance , Humans , Lactose Intolerance/diagnosis , Lactose Intolerance/epidemiology , Lactose Intolerance/genetics , Lactose Intolerance/therapy , Lactose Tolerance Test
6.
Rev. Assoc. Med. Bras. (1992, Impr.) ; Rev. Assoc. Med. Bras. (1992, Impr.);56(2): 230-236, 2010. tab
Article in Portuguese | LILACS | ID: lil-546945

ABSTRACT

Na maioria dos mamíferos a atividade da enzima lactase diminui na parede intestinal após o desmame, caracterizando a hipolactasia primária que provoca sintomas de intolerância à lactose. A intensidade dos sintomas de distensão, flatulência, dor abdominal e diarreia variam, dependendo da quantidade de lactose ingerida, e aumentam com o passar da idade. A hipolactasia é determinada geneticamente, porém uma mutação ocorreu para que fizesse parte da humanidade tolerar o leite na idade adulta. O diagnóstico é feito por teste de tolerância, empregando a lactose como desafio. Com a descoberta dos finlandeses do polimorfismo associado com a persistência da lactase, principalmente no norte da Europa, o exame genético passou a ser outra ferramenta diagnóstica mais confortável para o intolerante. No Brasil, 43 por cento dos brancos e dos mulatos têm alelo de persistência da lactase, sendo a hipolactasia mais frequente entre os negros e japoneses. Entretanto, na prática clínica indivíduos com hipolactasia podem ser orientados a consumir alguns derivados do leite e alimentos contendo lactose sem apresentar sintomas de intolerância, enquanto que outros terão que fazer restrição de lactose na dieta.


In most mammals, lactase activity declines on the intestinal wall after weaning, characterizing primary hypolactasia that provokes symptoms of lactose intolerance. The intensity of symptoms of distention, flatulence, abdominal pain and diarrhea varies, according to the amount of ingested lactose, and increases with age. Hypolactasia is genetically determined; nonetheless, a mutation occurred that had made a part of mankind tolerate milk in adulthood. Diagnosis is made by a tolerance test, using the lactose challenge. With the discovery made by the Finns of polymorphism associated with lactase persistence, mainly, in Northern Europe, the genetic test was incorporated as a more comfortable diagnostic tool for the intolerant. In Brazil, 43 percent of Caucasian and Mulatto groups have lactase persistence allele, with hipolactasia more frequently found among Blacks and Japanese. However, in clinical practice people with hypolactasia may be advised to consume certain dairy products and food containing lactose without developing intolerance symptoms, whereas others will need a lactose restriction diet.


Subject(s)
Humans , Lactose Intolerance , Lactose Intolerance/diagnosis , Lactose Intolerance/epidemiology , Lactose Intolerance/genetics , Lactose Intolerance/therapy , Lactose Tolerance Test
9.
Arq. ciências saúde UNIPAR ; 6(3): 135-140, set.-dez. 2002.
Article in Portuguese | LILACS | ID: lil-391904

ABSTRACT

A intolerância à lactose é uma inabilidade para digerir completamente a lactose, o açúcar predominante do leite. A lactose é um dissacarídeo e sua absorção requer hidrólise prévia no intestino delgado por uma b-galactosidase da borda em escova, comumente chamada lactase. A deficiência de lactase conduz à má-digestão da lactose e à conseqüente intolerância. A lactose não digerida, conforme passa pelo cólon, é fermentada por bactérias colônicas, havendo produção de ácidos orgânicos de cadeia curta e gases. Isto resulta em cólicas, flatulência, dor e diarréia osmótica. Existem dois tipos de deficiência de lactase. A deficiência de lactase do tipo primário é uma condição permanente. A forma congênita de deficiência de lactase é muito rara, enquanto a não persistência de lactase do tipo adulto é muito comum e afeta cerca de ¾ da população mundial. A deficiência de lactose secundária é, usualmente, condição temporária causada por dano à mucosa intestinal. Iogurte e outros produtos fermentados, bem como leites hidrolizados, amenizam os sintomas dos intolerantes. Da mesma forma, ingerir pequenas quantidades de leite a cada vez, ingerir leite juntamente com as refeições, usar preferencialmente leite integral e acrescentar chocolate ao leite podem aumentar a tolerância à lactose. Por outro lado, fatores psicológicos devem ser considerados no que diz respeito à intolerância à lactose, já que é sabido que as funções cerebrais exercem forte influência sobre a percepção de sintomas. Este trabalho revisa informações fundamentais sobre má digestão da lactose e intolerância à lactose e discute as possibilidades no tratamento dos intolerantes


Subject(s)
Humans , Lactose Intolerance , Lactose Intolerance/diet therapy , Lactose Intolerance/physiopathology , Lactose Intolerance/history , Lactose Intolerance/prevention & control , Lactose Intolerance/therapy , Nutritional Sciences/education
10.
Cahiers bioth ; (171): 39-40, août-sept. 2001.
Article in French | HomeoIndex Homeopathy | ID: hom-6203

ABSTRACT

Voici une plante aquatique, expérimentée par Nenning et Richter, qui rend bien des services en pédiatrie. Comme toutes les ombellifères, elle agit surtout (en expérimentation animale) sur les animaux femelles. Rappelons que... (AU)


Subject(s)
Case Reports , Humans , Female , Infant, Newborn , Phellandrium aquaticum/therapeutic use , Lactose Intolerance/therapy
13.
Rev Invest Clin ; 48 Suppl: 1-13, 1996 Nov.
Article in Spanish | MEDLINE | ID: mdl-9122542

ABSTRACT

The development of the practice of dairying allowed humans to become the only species of mammals to consume milk after the time of weaning. Milk contains the sugar, lactose, which requires the enzyme, intestinal lactase, to digest. Adult mammals do not retain ordinarily express this enzyme after early life, but through evolution, some groups of humans-notably those who practice dairying-have evolved to have the persistence of lactase into adulthood. In Meso-America, South America, Asia and most of Africa, the majority of individuals are genetically lactase non-persistent. With milk as an element of the diet, this human polymorphism for lactase produced its implication in gastroenterology, nutrition and food sciences for both those who can digest and those who cannot digest this sugar. Here, we review the issues of terminology, molecular genetics, diagnosis, health consequences, and management of different lactase states at a general and generic level.


Subject(s)
Lactose Intolerance , Adult , Health Status , Humans , Infant, Newborn , Lactase , Lactose Intolerance/diagnosis , Lactose Intolerance/genetics , Lactose Intolerance/therapy , Terminology as Topic , beta-Galactosidase/genetics
14.
Rev Invest Clin ; 48 Suppl: 33-43, 1996 Nov.
Article in Spanish | MEDLINE | ID: mdl-9122546

ABSTRACT

The main contributions in the knowledge of secondary lactase deficiency in children are reviewed. We present the clinical features of fermentative diarrhea and the current physiopathological issues, diagnostic procedures, and dietetic treatments, related to this diarrhea, as well as a review of the diseases associated with it. Finally, we discuss the epidemiological implications of the deficiency.


Subject(s)
Lactose Intolerance/epidemiology , beta-Galactosidase/deficiency , Child , Humans , Lactase , Lactose Intolerance/diagnosis , Lactose Intolerance/etiology , Lactose Intolerance/therapy
16.
Bol Asoc Med P R ; 81(5): 188-92, 1989 May.
Article in English | MEDLINE | ID: mdl-2660841

ABSTRACT

Lactose intolerance is a concern for the majority of the world's population. Persons who experience symptoms following the consumption of milk should consult with their physician. Symptoms may be eliminated or reduced with good dietary management that includes: 1. limiting milk consumption to one glass at a time; 2. drinking milk with other foods rather than alone; 3. eating yogurts instead of fluid milk; 4. using enzyme tablets to predigest the lactose in milk or to supplement the body's own lactase; 5. possibly eating small amounts of dairy foods each day to adapt the colonic bacteria. For an additional review of the research findings on lactose intolerance and milk drinking, the reader is directed to reference 4, a very recent and complete review by Scrimshaw and Murray. For information on dietary management of lactose intolerance suitable for the consumer, contact your local affiliate of the National Dairy Council.


Subject(s)
Dairy Products , Lactose Intolerance/therapy , Calcium/metabolism , Humans , Yogurt
18.
Rev. invest. clín ; Rev. invest. clín;37(4): 311-5, oct.-dic. 1985. tab
Article in Spanish | LILACS | ID: lil-26797

ABSTRACT

La entidad conocida como "Deficiencia de lactasa intestinal del tipo adulto" (DLITA) es una condición que se encuentra en más del 70% de la población mundial. Esto significa que entre los grupos portadores de esta característica, una proporción variable de ellos puede experimentar diarrea y otros síntomas gastrointestinales después de ingerir cierta cantidad de leche. No obstante, en muchos países pobres en los que la desnutrición infantil constituye un problema de importancia creciente, cuantiosos recursos se invierten en programas de alimentación basados en el reparto mativo de leche. En este trabajo presentamos los resultados de una encuesta que tuvo como objetivos: 1) Determinar la prevalencia de DLITA en una comunidad indígena, donde la desnutrición afecta a más del 60% de la población preescolar, y 2) Proponer alternativas para los programas de intervención nutricional en la región. De acuerdo al método empleado, de los 110 niños examinados 78% fueron clasificados como no absorbedores y 55% de ellos refirieron episodios de diarrea después de haber ingerido la lactosa. En la parte final de este trabajo se plantean algunas sugerencias, enfocadas a estrategias culturalmente asequibles y que pueden implementarse a corto, mediano y largo plazo en los programas regionales de nutrición comunitaria


Subject(s)
Adolescent , Humans , Male , Female , Lactose Intolerance/epidemiology , Nutrition Programs , Nutrition Surveys , Food, Fortified/administration & dosage , Lactose Intolerance/therapy , Lactose Tolerance Test , Mexico
20.
J Pediatr ; 79(5): 760-7, 1971 Nov.
Article in English | MEDLINE | ID: mdl-5171104

ABSTRACT

PIP: Hospitalized infants suffering from acute diarrhea were used to test simple bedside methods of determining reducing substances and pH in multiple fresh stool specimens. 332 infants were tested, and thetests were useful in detecting a reduced capacity to tolerate lactose in 77% of these patients. Lactose intolerance was considered to be present when the stools had a carbohydrate content greater than .25% and/or a pH of less than 6. 75 of 77 lactose-tolerant patients recovered within 3 weeks of administration of a milk formula, whereas 111 of 195 with mild intolerance and 13 of 60 with severe lactose intolerance recovered while receiving the milk formula. Diarrhea of greater than 3 weeks duration occurred in 27% of those cases with mild and in with untreated severe intolerance; however, with prompt dietary treatment, a 62% of those cases favorable response always occurred. Lactose intolerance was positively correlated with increased severity of malnutrition; there were no correlations with previous episodes of gastroenteritis, with presence of enteropathogens or with associated infections. When antibiotic therapy was instituted, the stool pH increased toward alkaline, but the excretion of carbohydrates was not modified.^ieng


Subject(s)
Diarrhea/etiology , Lactose Intolerance/complications , Acidosis/etiology , Animals , Body Height , Body Weight , Carbohydrates/analysis , Dehydration/etiology , Diarrhea/complications , Diarrhea/therapy , Diet Therapy , Dietary Carbohydrates/metabolism , Feces/analysis , Female , Gastroenteritis/complications , Glucose/analysis , Humans , Hydrogen-Ion Concentration , Infant , Infant Nutrition Disorders/etiology , Infant Nutritional Physiological Phenomena , Lactose Intolerance/diagnosis , Lactose Intolerance/therapy , Male , Milk , Time Factors
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