[Inherited factor VII deficiency and pregnancy. Apropos of 1 case]. / Déficit constitutionnel en facteur VII et grossesse. A propos d'un cas.

Hereditary factor VII deficiency is a rare autosomal recessive condition. Factor VII's level elevates during pregnancy in normal patients, as well in deficient individuals for some authors. Various treatments (fresh frozen plasma, prothrombin complex or factor VII concentrate) have been used to lessen the peri-partum hemorrhage in those factor VII-deficient pregnant women. We report the case of a pregnant woman presenting a factor VII deficiency (level 4%), without variation of level during her pregnancy. The single infusion of factor VII concentrate, prior to delivery, has elevated factor VII's level at 17% and has likely permitted minimal post-partum bleeding. The peripartum management of factor VII deficiency is discussed.

[Constitutional anomalies of hemostasis and management in surgical situation. Evaluation of 10 years' activity at the Hospital Centers of Aulnay-sous-Bois and Saint-Denis]. / Anomalies constitutionnelles de l'hémostase et conduite à tenir en situation chirurgicale. Bilan de dix ans d'activité aux Centres Hospitaliers d'Aulnay-sous-Bois et de Saint-Denis.

A ten-year retrospective study was conducted in 4 women in labor and 23 surgical patients with congenital clotting factor deficiency. Appropriate use of replacement therapy and good cooperation between biologists, anesthesiologists, and surgeons are essential to ensure a favorable outcome.

[Diagnostic and prognostic importance of laboratory tests in malaria in airports. Study of six recent cases]. / Importance diagnostique et pronostique des examens de laboratoire au cours du paludisme des aéroports. Etude de six cas récents.

During the summer 1994, six cases of airport malaria occurred in France, near the Roissy-Charles-de-Gaulle airport. Due to Plasmodium falciparum, all cases underwent rapid and severe deterioration, and in one case, the patient died. The role of laboratory tests is essential to establish the diagnosis of persons who have never resided in the endemic malaria areas and follow up with the patients already under treatment to detect possible complications.