RÉSUMÉ
The objective of this study was to assess the impact of 68Ga-prostate-specific membrane antigen (68Ga-PSMA) PET/CT on the management of prostate cancer in patients with biochemical recurrence (BCR). Methods: Documented management plans before and after 68Ga-PSMA PET/CT in 100 patients with BCR were retrospectively reviewed, and changes in plans were recorded. Results: Management changed after 68Ga-PSMA PET/CT in 39 patients (39%). The management changes occurred in 23 (33.8%) of 68 patients with radical prostatectomy and 16 (50%) of 32 patients previously treated with radical radiotherapy. Positive scan results (P < 0.001) and higher prostate-specific antigen (PSA) levels (P = 0.024) were associated with management changes. No significant association with management change was found for Gleason grade, stage, presence of metastatic disease, PSA velocity, or PSA doubling time. Conclusion:68Ga-PSMA PET/CT altered management in 39% of patients with BCR, and changes occurred more often in patients with radical radiotherapy treatment, positive 68Ga-PSMA scan results, and higher PSA levels.
Sujet(s)
Acide édétique/analogues et dérivés , Oligopeptides , Tomographie par émission de positons couplée à la tomodensitométrie , Tumeurs de la prostate/imagerie diagnostique , Sujet âgé , Sujet âgé de 80 ans ou plus , Isotopes du gallium , Radio-isotopes du gallium , Humains , Mâle , Adulte d'âge moyen , Tumeurs de la prostate/métabolisme , Tumeurs de la prostate/anatomopathologie , Tumeurs de la prostate/thérapie , Récidive , Études rétrospectivesRÉSUMÉ
The cause of low back pain due to lumbosacral transitional vertebra (LSTV) still remains a debated topic. Functional imaging with bone scintigraphy has been a valuable adjunct in its assessment; however, in recent years, the additional utility of single-photon emission tomography with computed tomography (SPECT/CT) is evolving as the imaging modality of choice in identifying range of complex lower back pain sources, leading to the provision of suitable treatment options. We present a case demonstrating a variant type of LSTV as a source of pain localized and delineated on hybrid SPECT/CT imaging treated by minimally invasive microendoscopic resection of the pseudoarticulations.