Sujet(s)
Hernie inguinale/imagerie diagnostique , Scrotum , Sujet âgé , Humains , Mâle , ScintigraphieRÉSUMÉ
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Sujet(s)
Mâle , Adulte , Humains , Ostéosarcome , Ostéosarcome/secondaire , Tumeurs du fémur/anatomopathologie , Tumeurs de la plèvreRÉSUMÉ
We report the case of a 62 year old man diagnosed of alkaptonuria who was referred to our department to undergo bone scintigraphy for polyarthralgia. The patient had a history of pain in lumbar and thoracic spine, right shoulder and left knee. Bone scintigraphy showed multiple joint disease with increased uptake in both shoulders, knees and spine. Higher uptake stood out in painful right shoulder and left knee joints. Ochronotic arthropathy that is developed in alkaptonuric patients is a degenerative joint disease. X-ray studies in this patient showed marked degenerative arthrosis in knees and shoulders, without more intense involvement in the symptomatic joints. Lumbar spine X-rays showed intervertebral disk calcification with disk collapse and fusion of the vertebral bodies with relative sparing of sacroiliac joint, which is a classic feature of ochronotic arthropathy. This case highlights the utility of bone scintigraphy in the evaluation of joint involvement as well as its correlation with clinical course and potential usefulness in the follow-up of this disease.
Sujet(s)
Alcaptonurie/complications , Maladies articulaires/imagerie diagnostique , Maladies articulaires/étiologie , Ochronose/imagerie diagnostique , Ochronose/étiologie , Humains , Mâle , Adulte d'âge moyen , ScintigraphieSujet(s)
Médecine factuelle , Médecine nucléaire/méthodes , Algorithmes , Biais (épidémiologie) , Prise en charge personnalisée du patient , Prise de décision , Diagnostic , Humains , Jugement , Valeur prédictive des tests , Reproductibilité des résultats , Plan de recherche , Sensibilité et spécificitéSujet(s)
Médecine factuelle , Médecine nucléaire , Prise en charge personnalisée du patient , Essais cliniques comme sujet/méthodes , Méthode en double aveugle , Medline , Essais contrôlés randomisés comme sujet , Reproductibilité des résultats , Plan de recherche , Littérature de revue comme sujet , Risque , Méthode en simple aveugleRÉSUMÉ
OBJECTIVE: To verify the utility of diuretic renography using 99mTc-MAG3 in the evaluation of the urinary tract obstruction in patients with prenatal diagnosis of hydronephrosis. In a neonate with upper urinary tract dilatation, it is difficult to differentiate a true obstruction from a dilated non-obstructed system. MATERIAL AND METHODS: The retrospective study (january 1993-december 1998) included 40 consecutive patients selected from 181 newborns with a prenatal diagnosis of hydronephrosis. The mean age of the performance of the first renography was 2.6 months. RESULTS: The final diagnosis (once the vesicoureteral reflux was ruled out) was: ureteropelvic junction obstruction (UPJ) 16, megaureter 15, ureterocele 3 and stasis 6. Conservative treatment was applied in most of the patients. Nevertheless, 17 of them needed surgical treatment due to the high risk of the permanent renal damage. CONCLUSIONS: 1) UPJ is the most frequent cause of neonatal hydronephrosis (NH) and consequently, of the request for diuretic renographies. The renography with 99mTc-MAG3 has the greatest influence in the therapeutic decision (identifying who should be operated on and when this should be done), due to the fact that it is the disease with the highest rate of surgical interventions. 2). The surgical indication in NH is based on the diuretic renography parameters and/or on the presence of symptomatology. In our series of surgical patients, none of those who had a differential renal function <20% with regard to the contralateral one showed recuperation after surgery (control 6 months later).