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1.
PeerJ ; 12: e17984, 2024.
Article de Anglais | MEDLINE | ID: mdl-39247545

RÉSUMÉ

Background: Sequestering carbon dioxide (CO2) in agricultural soils promises climate change mitigation as well as sustainable ecosystem services. In order to stabilize crop residues as soil carbon (C), addition of mineral nutrients in excess to crop needs is suggested as an inevitable practice. However, the effect of two macronutrients i.e., nitrogen (N) & phosphorus (P), on C cycling has been found contradictory. Mineral N usually decreases whereas mineral P increases the soil organic C (SOC) mineralization and microbial biomass. How the addition of these macronutrients in inorganic form to an organic-matter poor soil affect C cycling remains to be investigated. Methods: To reconcile this contradiction, we tested the effect of mineral N (120 kg N ha-1) and/or P (60 kg N ha-1) in presence or absence of maize litter (1 g C kg-1 soil) on C cycling in an organic-matter poor soil (0.87% SOC) in a laboratory incubation. Soil respiration was measured periodically during the incubation whereas various soil variables were measured at the end of the incubation. Results: Contrary to literature, P addition stimulated soil C mineralization very briefly at start of incubation period and released similar total cumulative CO2-C as in control soil. We attributed this to low organic C content of the soil as P addition could desorb very low amounts of labile C for microbial use. Adding N with litter built up the largest microbial biomass (144% higher) without inducing any further increase in CO2-C release compared to litter only addition. However, adding P with litter did not induce any increase in microbial biomass. Co-application of inorganic N and P significantly increased C mineralization in presence (19% with respect to only litter amended) as well as absence (41% with respect to control soil) of litter. Overall, our study indicates that the combined application of inorganic N and P stabilizes added organic matter while depletes the already unamended soil.


Sujet(s)
Azote , Phosphore , Microbiologie du sol , Sol , Sol/composition chimique , Phosphore/composition chimique , Azote/métabolisme , Dioxyde de carbone/pharmacologie , Biomasse , Cycle du carbone , Carbone/métabolisme , Agriculture/méthodes , Zea mays/composition chimique , Engrais/analyse
2.
Clin Psychol Psychother ; 31(4): e3032, 2024.
Article de Anglais | MEDLINE | ID: mdl-39109808

RÉSUMÉ

BACKGROUND: Mental health crisis rates in the United Kingdom are on the rise. The emergence of community mental health models, such as Crisis Resolution Home Treatment Teams (CRHTTs), offers a vital pathway to provide intensive assessment and treatment to individuals in their homes, including psychological interventions. Previous qualitative literature has identified facilitators and barriers to the implementation of psychological interventions within CRHTT settings; however, a synthesis of this literature has not yet been conducted. To address this gap, a systematic review was undertaken with the aim of identifying the reported facilitators and barriers of implementing evidence-based psychological interventions in CRHTTs. METHOD: A systematic review and narrative synthesis were conducted. Studies were included if they examined the implementation of evidence-based psychological interventions in a CRHTT setting. The study population had to be 18 and over and could include healthcare professionals working in CRHTTs, service users of CRHTTs, or family and carers of CRHTT service users. Studies of any formal research methodology were included. Four databases were searched (MEDLINE, CINAHL Plus, Embase and PsycINFO), along with Google Scholar, to identify eligible studies. RESULTS: Six studies were identified, using mixed qualitative and quantitative methodologies, with the predominant focus being the exploration of stakeholder perspectives on care implementation within CRHTTs, encompassing aspects including but not restricted to psychological care implementation. The literature was deemed to be of moderate to high quality. Facilitators included adapting psychological therapies, prioritizing the therapeutic relationship, increasing psychological skills and training of CRHTT staff and psychologically informed CRHTT models. The barriers identified included a medical model bias within teams, resource constraints and elements pertaining to CRHTT services. CONCLUSIONS: Further robust research in this area is imperative. We recommend that future research be implemented in the form of service evaluations and randomized controlled trials (RCTs) and that the principles of implementation science be used to assess and develop the evidence base for psychological intervention delivery in CRHTTs.


Sujet(s)
Intervention de crise , Services de soins à domicile , Troubles mentaux , Intervention psychosociale , Humains , Intervention de crise/méthodes , Intervention psychosociale/méthodes , Troubles mentaux/thérapie , Troubles mentaux/psychologie , Services communautaires en santé mentale/méthodes , Royaume-Uni , Équipe soignante
3.
Pak J Pharm Sci ; 37(2(Special)): 459-462, 2024 Mar.
Article de Anglais | MEDLINE | ID: mdl-38822550

RÉSUMÉ

The purpose of this study was to examine the potential hypoglycemic effects of administering ginger (Zingiber officinale) and garlic (Allium sativum) to rats with induced type 2 diabetes. A total of forty-five male adult albino rats were randomly assigned to five groups. The groups were named Normal Control, Diabetic Control, Ginger group, Garlic group and a combination group of ginger and garlic. Diabetes was produced in all groups, except the normal control group, using an intraperitoneal injection of streptozotocin at a dosage of 60 mg/body weight. During the course of two months, rats were administered varying amounts of ginger and garlic powders as part of their treatment After the experiment concluded, measurements were taken for glycated hemoglobin, serum glucose, insulin, cholesterol, high density protein, low density protein and liver glycogen levels. These groups exhibited considerably greater serum insulin and high-density lipoprotein concentrations (P<0.05) compared to the diabetic control group. Conversely, body weight, fasting blood glucose, total cholesterol, low density lipoprotein, and glycated hemoglobin levels were significantly lower (P<0.05) in all groups compared to the diabetic control group. A statistically significant increase (P<0.05) increase shown in liver glycogen levels. This study proposes that the utilization of ginger and garlic powders improve the condition of type 2 diabetes and maybe reduce the risk of subsequent diabetic complications.


Sujet(s)
Glycémie , Diabète expérimental , Ail , Hypoglycémiants , Insuline , Poudres , Zingiber officinale , Animaux , Ail/composition chimique , Zingiber officinale/composition chimique , Diabète expérimental/traitement médicamenteux , Diabète expérimental/sang , Mâle , Glycémie/effets des médicaments et des substances chimiques , Glycémie/métabolisme , Hypoglycémiants/pharmacologie , Hypoglycémiants/usage thérapeutique , Rats , Insuline/sang , Diabète de type 2/traitement médicamenteux , Diabète de type 2/sang , Hémoglobine glyquée/métabolisme , Extraits de plantes/pharmacologie , Phytothérapie , Glycogène hépatique/métabolisme , Streptozocine
4.
Chem Biol Technol Agric ; 9(1): 58, 2022.
Article de Anglais | MEDLINE | ID: mdl-37520585

RÉSUMÉ

Sustainable food security is a major challenge in today's world, particularly in developing countries. Among many factors, environmental stressors, i.e., drought, salinity and heavy metals are major impediments in achieving sustainable food security. This calls for finding environment-friendly and cheap solutions to address these stressors. Plant growth-promoting rhizobacteria (PGPR) have long been established as an environment-friendly means to enhance agricultural productivity in normal and stressed soils and are being applied at field scale. Similarly, pyrolyzing agro-wastes into biochar with the aim to amend soils is being proposed as a cheap additive for enhancement of soil quality and crop productivity. Many pot and some field-scale experiments have confirmed the potential of biochar for sustainable increase in agricultural productivity. Recently, many studies have combined the PGPR and biochar for improving soil quality and agricultural productivity, under normal and stressed conditions, with the assumption that both of these additives complement each other. Most of these studies have reported a significant increase in agricultural productivity in co-applied treatments than sole application of PGPR or biochar. This review presents synthesis of these studies in addition to providing insights into the mechanistic basis of the interaction of the PGPR and biochar. Moreover, this review highlights the future perspectives of the research in order to realize the potential of co-application of the PGPR and biochar at field scale.

5.
Int J Biomater ; 2018: 1963024, 2018.
Article de Anglais | MEDLINE | ID: mdl-30302092

RÉSUMÉ

Polylactic acid (PLA) is a biodegradable thermoplastic polyester. In 2010, PLA became the second highest consumed bioplastic in the world due to its wide application. Conventionally, PLA is produced by direct condensation of lactic acid monomer and ring opening polymerization of lactide, resulting in lower molecular weight and lesser strength of polymer. Furthermore, conventional methods of PLA production require a catalyst which makes it inappropriate for biomedical applications. Newer method utilizes metabolic engineering of microorganism for direct production of PLA through fermentation which produces good quality and high molecular weight and yield as compared to conventional methods. PLA is used as decomposing packaging material, sheet casting, medical implants in the form of screw, plate, and rod pin, etc. The main focus of the review is to highlight the synthesis of PLA by various polymerization methods that mainly include metabolic engineering fermentation as well as salient biomedical applications of PLA.

6.
Acta Crystallogr Sect E Struct Rep Online ; 66(Pt 4): o868-9, 2010 Mar 20.
Article de Anglais | MEDLINE | ID: mdl-21580690

RÉSUMÉ

In the title compound, C(14)H(20)N(2)O(3)S, the cyclo-hexyl ring adopts a chair conformation: the four coplanar C atoms of this ring make a dihedral angle of 64.8 (2)° with the benzene ring. In the mol-ecule, an intra-molecular C-H⋯O contact generates an S(6) ring motif. In the crystal structure, mol-ecules are linked via inter-molecular N-H⋯O hydrogen bonds into two-dimensional layers propagating in (100).

7.
Acta Crystallogr Sect E Struct Rep Online ; 66(Pt 8): o1989, 2010 Jul 10.
Article de Anglais | MEDLINE | ID: mdl-21588304

RÉSUMÉ

The title compound, C(12)H(16)BrNO(2)S, adopts an L-shaped conformation with the central C-S-N-C torsion angle being -77.8 (3)°. The crystal packing features N-H⋯O hydrogen bonds, which lead to C(4) chains propagating in [010]; the second O atom is involved in short intra-molecular C-H⋯O contacts.

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