RÉSUMÉ
The digestive tract is an uncommon location of acute ischemia, especially when caused paradoxical embolism. We report the case of a 69-year-old patient initially hospitalized for a acute ischemia of the upper limb. Physical examination and complementary tests enabled the diagnosis of paradoxical embolism with bilateral pulmonary embolism leading to elevated pressure in the pulmonary arteries, which opened the oval foramen. The patient also presented ischemia involving the digestive trunks, the upper limb and the kidneys. Rapid diagnosis is a major challenge in this condition controlling the prognosis of this uncommon disease.
Sujet(s)
Bras/vascularisation , Système digestif/vascularisation , Embolie paradoxale/imagerie diagnostique , Ischémie/étiologie , Artère pulmonaire/imagerie diagnostique , Embolie pulmonaire/imagerie diagnostique , Sujet âgé , Pression sanguine , Électrocardiographie , Foramen ovale perméable/imagerie diagnostique , Humains , Mâle , Artère mésentérique supérieure/imagerie diagnostique , Artère mésentérique supérieure/anatomopathologie , Artère pulmonaire/physiopathologie , Radiographie , ÉchographieRÉSUMÉ
Antibodies were raised against the beef heart mitochondrial ATPase inhibitor. This antiserum prevented the ability of the ATPase inhibitor to inhibit the F1 ATPase activity. Peptide fragments obtained by enzymatic cleavage of the inhibitor protein were tested by immunoblotting or ELISA for their response to the anti-inhibitor antiserum. An antigenic determinant was located in the sequence spanning His 48 to Lys 58 of the inhibitor molecule.