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1.
Heliyon ; 9(12): e22965, 2023 Dec.
Article de Anglais | MEDLINE | ID: mdl-38076104

RÉSUMÉ

Background: There is mounting evidence that Ethiopia is becoming a more street-food-consuming nation. The hygienic and safety procedures, however, are not adequately evaluated. Objectives: This study aimed to determine the magnitude of food safety and hygiene practices and associated factors among street food vendors of Bahir Dar City. Method: A community-based cross-sectional study design was conducted from March 10 to April 10, 2019. The data were collected using an interviewer-administered questionnaire with an observational checklist. The collected data were entered into EPI Data and analyzed by R software. Descriptive statistics were computed. A Binary logistic regression model was fit to identify the association and strength of exploratory variables and food safety and hygiene practices at a 95 % confidence interval and p-value <0.05. Results: A total of 421 participants participated. The level of good food safety and hygiene practices was 36 % (95%CI: 31, 41). Monthly income of >2500 Birr (AOR = 4.99; 95%CI: 2.42, 10.3), work experience of >2 years (AOR = 2.05; 95%CI: 1.15, 3.65), having supervision by health professionals (AOR = 2.45; 95%CI: 1.25, 4.85), having good knowledge about food safety and hygiene (AOR = 3.84; 95%CI: 1.42, 10.36), and having a favorable attitude towards food safety and hygiene (AOR = 2.71; 95%CI: 1.12, 6.57) were determinants of food safety and hygiene practice. Conclusions: The level of good food safety and hygiene practices was low. Monthly income, work experience, supervision by health professionals, knowledge, and attitude toward food safety and hygiene were identified as the determinants of good food safety and hygiene practice.

2.
PLoS One ; 18(1): e0276676, 2023.
Article de Anglais | MEDLINE | ID: mdl-36630465

RÉSUMÉ

BACKGROUND: Community-Based Health Insurance (CBHI) is an evolving program for delivering financial protection against the cost of illness and enhancing access to quality health services for low-income informal households. OBJECTIVE: The study aimed to identify determinants of household dropout from a CBHI program in Mecha district, North West Ethiopia, 2019. METHODS: A community-based case-control study was conducted in the Mecha district from March 10 to June 10, 2018. The final sample was 634 (317 cases and 317 controls) determined by the two-population proportion formula, and these samples were selected using a multi-stage sampling technique. The collected data was entered into Epi-data version 3.1 and analyzed using R version 4.0 software. Descriptive statistics computed. A simple logistic analysis was run (at 95% CI and p-value < 0.05) to identify the determinants for the dropout from CBHI. RESULTS: Poor perceived quality of care (AOR = 3.66; 95%CI: 2.35, 5.69), low knowledge of community-based health insurance (AOR = 6.02; 95%CI: 2.97, 12.26), no active community communication (AOR = 5.41; 95%CI: 3.29, 8.90) no chronic illness (AOR = 10.82; 95%CI: 5.52, 21.21) premium fee is not affordable (AOR = 2.35; 95%CI: 1.47, 3.77), and out of pocket money not reimbursed (AOR = 9.37; 95%CI: 4.44, 19.77) were the determinants for the dropout from CBHI. CONCLUSIONS: Poor perceived quality of care, low knowledge of CBHI, no active community participation, no chronic illness, premium fees are not affordable, and out-of-pocket money not reimbursed were the determinants for the dropout from CBHI.


Sujet(s)
Assurance maladie communautaire , Humains , Éthiopie , Études cas-témoins , Caractéristiques familiales , Enquêtes et questionnaires , Assurance maladie
3.
BMC Psychiatry ; 22(1): 674, 2022 11 01.
Article de Anglais | MEDLINE | ID: mdl-36319991

RÉSUMÉ

BACKGROUND: Common mental disorders are severe and frequent co-morbid psychiatric illnesses with epilepsy. Different study findings across the world showed that patients with epilepsy have a higher burden of mental disorders than the general population. However, these issues in patients with epilepsy have been consistently undiagnosed. OBJECTIVES: The study aimed to screen common mental disorders and the determinants among patients with epilepsy attending at Fenote Selam hospital. METHODS: An institutional-based cross-sectional study was conducted among patients with Epilepsy from March 10 to May 15, 2019. Patients were assessed for the risk of common mental disorders using a pretested, structured, self-reporting questionnaire (SRQ-20). The collected data were entered into Epi-data version 3.1 software and analyzed using R version 4.0 software. Descriptive statistics were computed using frequency, percent, mean, and standard deviations. A simple logistic regression model was fit to identify the association and strength of exploratory variables and common mental disorders at a 95% confidence interval and p-value < 0.05. RESULTS: The study included 202 patients diagnosed with epilepsy and yielded a response of 91.4%. About 53% of the patients were males. The magnitude of common mental disorders among patients with epilepsy was 57.9% (95% CI: 44.56, 71.24). Being more than one substance user (AOR = 5.7; 95%CI: 1.6, 20.7) and Not having social support (AOR = 4.3; 95%CI: 1.5, 11.9) were the identified determinants of common mental disorders. CONCLUSION: The magnitude of common mental disorders among patients with epilepsy were high. Not having social support and khat chewing were the identified risk factors significantly associated with common mental disorders. Early screening and treatments are the key interventions to prevent complications and deaths from common mental disorders.


Sujet(s)
Épilepsie , Troubles mentaux , Mâle , Humains , Femelle , Études transversales , Éthiopie/épidémiologie , Prévalence , Troubles mentaux/épidémiologie , Épilepsie/complications
4.
PLoS One ; 17(11): e0276763, 2022.
Article de Anglais | MEDLINE | ID: mdl-36327276

RÉSUMÉ

BACKGROUND: Coronavirus disease has spread worldwide since late 2019. Vaccination is critical in controlling this pandemic. However, vaccine acceptance among pregnant women is not well-studied. Therefore, this study aimed to assess the COVID-19 vaccine acceptance and associated factors among pregnant women attending antenatal care clinics in Gondar town, Northwest Ethiopia. METHODS: An institution-based cross-sectional study was conducted among pregnant women attending antenatal care clinics at Gondar town, Northwest Ethiopia, 2021. About 510 study subjects were selected using a systematic random sampling technique from August 25 to September 10/2021. Data collection was done by using an interviewer-administered, structured questionnaire. Epi-info 7.2 was used to enter data and then exported to SPSS version 25 software for analysis. Bivariable and multivariable binary logistic regression models were used to identify factors associated with the outcome variable. Variables with a p-value < 0.2 in the bivariable analysis were entered into the multivariable analysis to control for possible confounders. Statistical significance is determined using an adjusted odds ratio and 95% confidence interval (CI) at a p-value of < 0.05. RESULTS: Of 510 participants, 211 (41.4%) were willing to take COVID-19 vaccines. Maternal age ≥ 35 years (AOR: 5.678, 95% CI: 1.775-18.166), having contact history with COVID-19 diagnosed people (AOR: 7.724, 95% CI: 2.183, 27.329), having a pre-existing chronic disease (AOR: 3.131, 95% CI: 1.700-5.766), good knowledge about COVID-19 vaccine (AOR: 2.391, 95% CI: 1.144, 4.998) and good attitude towards COVID-19 vaccine (AOR: 2.128, 95% CI: 1.348) were significantly associated with the outcome variable. CONCLUSIONS: The willingness to take COVID-19 vaccine among pregnant mothers was low. Age, contact history with COVID-19 diagnosed people, chronic disease, knowledge, and attitude towards COVID-19 vaccine were factors associated with COVID-19 vaccine willingness. To enhance the COVID-19 vaccine acceptance, the government with different stakeholders should strengthen public education about the importance of getting COVID-19 vaccine.


Sujet(s)
COVID-19 , Femmes enceintes , Femelle , Humains , Grossesse , Adulte , Études transversales , Vaccins contre la COVID-19/usage thérapeutique , COVID-19/épidémiologie , COVID-19/prévention et contrôle , Éthiopie/épidémiologie , Établissements de soins ambulatoires
5.
PLoS One ; 17(5): e0267189, 2022.
Article de Anglais | MEDLINE | ID: mdl-35587937

RÉSUMÉ

BACKGROUND: Cancer is the leading cause of morbidity and mortality globally. In Ethiopia, 5.8% of deaths are attributed to cancer. Therefore, this study aimed to examine the cancers preventive practice and associated factors in North West Ethiopia, 2019. METHODS: A community-based cross-sectional study was conducted among Bahir Dar city residents. A multistage sampling technique was used to select 845 study participants. Data were collected through a validated interviewer administered questionnaire. The questionnaire was adapted from the American cancer association cancer prevention toolkit. Descriptive statistics were computed and presented in charts and texts. The model fitness was checked using Hosmer and Lemeshow goodness of fit (P > 0.05). Bivariable and multivariable logistic regressions were used to identify factors associated with cancer preventive practice. A p-value < 0.2 at bivariate analysis was candidate variables for multivariable logistic regression analysis. Finally, p-value of < 0.05 was considered as a statistically significant predictor for cancer preventive practice at the 95% confidence interval. RESULT: A total of 845 study participants took part in the study. Nearly 63% of the respondents were females. About 28% (95%CI: 24, 30) of the study participants had good preventive practice. Age ≥ 45 years (AOR = 0.31; 95%CI: 0.15, 0.62), female (AOR = 0.50, 95%CI: 0.35, 0.71) family member with cancer (AOR = 1.68, 95%CI: 1.07, 2.62) and had good knowledge (AOR = 1.66, 95%CI: 1.14, 2.42) were the identified determinants of cancer preventive practices. CONCLUSION: This study revealed that the level of cancer preventive practices was low. Family member with cancer, knowledge about cancer, older age, and being female were significantly associated with cancer preventive practices. This finding underscores the importance of interventions to enhance cancer preventive practices.


Sujet(s)
Tumeurs , Études transversales , Éthiopie/épidémiologie , Femelle , Connaissances, attitudes et pratiques en santé , Humains , Modèles logistiques , Mâle , Adulte d'âge moyen , Tumeurs/épidémiologie , Tumeurs/prévention et contrôle , Enquêtes et questionnaires
6.
SAGE Open Med ; 9: 20503121211054970, 2021.
Article de Anglais | MEDLINE | ID: mdl-34777805

RÉSUMÉ

INTRODUCTION: Health care workers are at the frontline of the response against the COVID-19 outbreak. Poor preparedness and infection prevention practices among health care workers compound the hazard and occurrence of COVID-19 hospital transmission. Thus, the study aimed to assess preparedness toward COVID-19 pandemics and associated factors among health care workers in Hospitals of Eastern Ethiopia. METHODS: Facility-based cross-sectional study was conducted from 20 June to July 10 2020. A simple random sampling technique was used to select 423 health care workers. Data were collected using a structured self-administered questionnaire and analyzed using SPSS Version 23. Bivariate and multivariable logistic regression was conducted to identify factors associated with the outcome variable, and statistical significance was declared at a p-value less than 0.05. RESULTS: This study revealed that the proportion of health care workers' preparedness toward the COVID-19 pandemic was 40.9% (95% CI: 36.2-45.9). Working in a public hospital (AOR = 2.7, 95% CI: 1.6-4.3), being unafraid of transmitting COVID-19 to patients (Adjusted odds ratio/AOR = 4.6, 95% CI: 2.2-10.0), feeling safe at the workplace (AOR = 3.3, 95% CI: 1.7-6.4)), satisfied with the infection control policy (AOR = 6.0, 95% CI: 2.3-15.0), and not feeling anxious about the likelihood of COVID-19 spread (AOR = 2.1, 95% CI: 1.3-3.4) were significantly associated with COVID-19 preparedness. CONCLUSION: The majority of the health care workers were not prepared for COVID-19 pandemics. Feeling safe at the workplace scared of transmitting COVID-19 to patients, satisfied with the infection control policy, and feeling anxious concerning the likelihood of COVID-19 were factors associated with health care workers' preparedness to COVID-19. The current awareness creation training, including motivational and psychological preparation for all health care workers, is mandatory, regardless of their profession or working place.

7.
BMC Nutr ; 7(1): 20, 2021 Jun 07.
Article de Anglais | MEDLINE | ID: mdl-34092250

RÉSUMÉ

BACKGROUND: Nutritional awareness and practice of women during pregnancy could be determining their nutritional status, which significantly affects the outcome of pregnancy. Therefore this study aims to explore the maternal nutrition counseling provided by health professionals for pregnant women, Barriers to maternal nutrition, and major interventions. METHODS: A descriptive study design with a qualitative method by using ground theory tradition, based on constructivist research approach and Charmaz's (2000) study design has been conducted from September-01/2019 _November-16/2019 among pregnant women who got ANC service in Addis Ababa, Ethiopia. A purposive sampling technique was used. Practical observations and in-depth interviews were conducted. The sample size adjustment has been carried out according to the information saturation obtained, and finally, 81 practical observations, In-depth interview with two center managers, nine health professionals and eleven term pregnant women has been conducted. An observational checklist and Semi-structured, open-ended questionnaires were used. Data, the environment, and methodological triangulation were carried out. A conceptual framework has been established based on the data collected about the whole process of maternal nutrition counseling during pregnancy. ATLAS TI software was utilized for information analysis. THE RESULTS: Most participants responded that maternal nutrition counseling provided to pregnant mothers is not adequate and neglected by most stakeholders. From 81 practical observations, health professionals counseled to mothers were 10 what to feed, 4 what to limit to consume, and 5 were counseled about what to eat during pregnancy. Close to all the respondents agreed on the importance of providing nutrition counseled by the nutritionists. Most of the study participants emphasized a shortage of time as primary barriers. Institutional Barriers, Professional Barriers, Maternal Barriers, and Community Barriers were major barriers to nutrition counseling. CONCLUSIONS: Generally, maternal nutrition counseling provided to pregnant mothers was not adequate and neglected by most stakeholders. Shortage of time due to client flow, Institutional Barriers, Professional Barriers, Maternal Barriers, and Community Barriers were major categories of maternal nutritional counseling barriers. Information update and timely preparation were recommended to health professionals.

8.
HIV AIDS (Auckl) ; 13: 571-579, 2021.
Article de Anglais | MEDLINE | ID: mdl-34079384

RÉSUMÉ

BACKGROUND: Human immunodeficiency virus (HIV) positive status non-disclosure to a sexual partner is a public health problem where a high prevalence of HIV infection is reported in a region with poor partner disclosure status. This study aimed to assess HIV-positive status disclosure to sexual partners and associated factors among adult HIV clients at Debre Markos town, Amhara Regional State Ethiopia, in 2019. METHODS: A facility-based cross-sectional study was conducted among 406 adult HIV-positive clients in Debre Markos town from September 1 to 30, 2019. Epidata version 3.1 for data entry and SPSS version 25 for data analysis were used. Bivariable and multivariable logistic analyses at (p<0.05) were performed. RESULTS: From 421 study participants, 406 were participated giving response rate of 96.4%. The proportion of HIV status disclosure to sexual partner was 92.6%. Male sex (AOR = 2.863, 95%, CI = 1.147-7.146), urban residence (AOR = 2.438, 95% CI = 1.032-5.759), knowing sexual partner's HIV status (AOR = 2.749, 95% CI = 1.015-7.441), good anti-retroviral medication adherence status (AOR = 2.445, 95% CI = 1.023-5.845), and being a member of an anti-HIV club (AOR = 3.07, 95% CI = 1.314-7.171) were factors significantly associated with HIV-positive status disclosure at p value <0.05. CONCLUSIONS AND RECOMMENDATION: The proportion of HIV-positive status disclosure to sexual partners was high. This study recommended that it is better to promote antiretroviral treatment adherence counseling, mutual partner HIV testing, and membership of anti-HIV/acquired immune deficiency syndrome (AIDS) club through extensive health education with particular attention given to females and rural residents.

9.
Risk Manag Healthc Policy ; 14: 1299-1310, 2021.
Article de Anglais | MEDLINE | ID: mdl-33790675

RÉSUMÉ

BACKGROUND: Coronavirus disease 19 was observed as a pandemic and caused many community health problems that resulted in Global issues. It causes death for many individuals including health professionals. This study aimed to determine the occupational health safety of health professionals and associated factors during COVID-19 pandemic at North Showa. METHODS: Institutions-based Cross-sectional study was conducted using a simple random sampling technique from May 10 to June 15, 2020. Interviewer-administered questioners were used, and data were entered into Epi-data version 3.1 and exported to SPSS 23 for analysis. Bi-variable logistic regression was carried out to select candidate variables with a cutoff point < 0.2. Finally, multivariable logistic regression was conducted to identify significant variables. An adjusted odds ratio with 95% CI at a 5% level of significance was used to measure the strength of association. P-value <0.05 indicated a significant association between variables. RESULTS: A total of 280 health professionals participated with a 92.72% response rate. Of which 57.9% (n=162) were males while 42.1% (n=118) females. Of total 48.9% (n=137) (95% CI: 43.2, 55.0) health professionals had poor occupational health and safety. Availability of soap and bleach (AOR=2.50; 1.439, 4.356), Possibility of isolate COVID-19 suspected clients (AOR=2.525; 1.690, 5.062), Availability of infections prevention and control program standards and policy (AOR=2.329; 1.325, 4.092), Availability of policy and procedure to prevent COVID-19 (AOR= 2.427; 1.389, 4.240) were significantly associated. CONCLUSION: The result suggested that occupational health safety was generally low in the study area. Therefore, a preventive measure such as the use of personal protective equipment and adherence to hand hygiene practice and Infection prevention policy could reduce the spread of COVID-19 and further study should be conducted to generate more evidence on determinants of occupational health safety.

10.
PLoS One ; 16(4): e0248108, 2021.
Article de Anglais | MEDLINE | ID: mdl-33844683

RÉSUMÉ

BACKGROUND: Stunting is a well-established child-health indicator of chronic malnutrition, which reliably gives a picture of the past nutritional history and the prevailing environmental and socioeconomic circumstances. OBJECTIVE: To investigate the prevalence of stunting and associated factors among public primary school children of the Bahir Dar city. METHOD: A cross-sectional study was carried out from March to June 2019. Data were coded and entered into the Epi-Data and exported to SPSS version 23 software. The pupil was stunted if the height- for-age was ≤ -2 SDs from the median growth standards according to the WHO. A descriptive summary was computed using frequency, percent, mean, median and standard deviation. A simple logistic regression model was fitted to identify associated factors between the independent variables and the dependent variable at a 95% confidence interval (CI) and p-value <0.05. RESULTS: 370 primary school pupils were included in the study with the mean age of 10.15 (± 2.23 SD) years. 51.6% of the pupils were females. The total prevalence of stunting was 15.13% (95%CI; 11%, 19%). The burden of stunting was higher in the age group of 11 years and older. Pupil's age older than 11 years (AOR = 15. 6; 95%CI; 3.31, 73.45; p-value < 0. 001) and male sex (AOR = 7. 07; 95%CI: 2.51, 19.89; p-value < 0. 0002) were significantly associated with stunting. CONCLUSION: The prevalence of stunting was relatively lower than the regional estimated stunting level. Older age and male sex were significantly associated with stunting.


Sujet(s)
Phénomènes physiologiques nutritionnels chez l'adolescent/physiologie , Troubles de la croissance/épidémiologie , Adolescent , Enfant , Études transversales , Régime alimentaire , Éthiopie/épidémiologie , Femelle , Humains , Mâle , Prévalence , Facteurs de risque , Population rurale , Établissements scolaires , Facteurs socioéconomiques , Population urbaine
11.
Hum Antibodies ; 29(2): 149-169, 2021.
Article de Anglais | MEDLINE | ID: mdl-32865183

RÉSUMÉ

BACKGROUND: COVID-19 is currently the major public health burden in the world, with disease and death in the global community from COVID-19 increasing rapidly from time to time worldwide. However, there has been a lack of well-organized information about the level of risk, effects, prevention and control methods of the disease. Therefore the aim of this study is to identify and review a published level of risk, effects response to potential health emergencies, prevention, and control methods of COVID-19 at a global level. METHOD: A systematic review was performed after literatures were identified by searching the following online databases: medRxiv, Google scholar, PubMed, MEDLINE, EMBASE, and the Cochrane Library with supplementary hand searching of conferences. The online databases contain archives of most English biomedical journals. Scientific papers published online by the Center for Disease Control and the World Health Organization were also included for this analysis. The scientific publications from 01 December, 2019 to 13 April 2020 were included. The 'COVID-19', '2019 novel coronavirus', '2019-nCoV', 'novel coronavirus', and 'Pneumonia' key search terms were used for this review.


Sujet(s)
COVID-19/prévention et contrôle , COVID-19/thérapie , Urgences , Services des urgences médicales , Prévention des infections/méthodes , Humains
12.
Hum Antibodies ; 29(2): 129-137, 2021.
Article de Anglais | MEDLINE | ID: mdl-32865184

RÉSUMÉ

BACKGROUND: The Novel Coronavirus Disease 2019 (COVID-19) has proved to be one of the most burdensome respiratory disease outbreaks ever. Moreover, the public health emergency of the COVID-19 outbreak has been seen by the World Health Organization (WHO) as global health concern since March 2020 and there has been a significantly increased morbidity and mortality in the community worldwide. The objective of this review is to describe and review the global public health significances and community and healthcare perception of features, treatments, prevention and control methods to slow the transmission of the outbreak. METHODS: For this review, the literature has been searched by following online databases, including medRxiv, pubmed, medline and Google scholar databases. The key search terms 'COVID-19', '2019 novel coronavirus', '2019-nCoV', 'novel coronavirus' and 'Pneumonia' were used to search the literature. Scientific papers published online by the Center for Disease Control (CDC) and the WHO from 01 January to 06 May 2020 in the English language were included for analysis. RESULTS: The results of this review indicated that COVID-19 is a serious global public health problem. It affects immune compromised individuals living with chronic diseases, the elderly and pregnant women more severely. The disease spread rapidly from one country to countries worldwide. In all, 212 countries highlighted the weakened state of essential public health and emergency services. The researchers addressed the lack of perception in communities, including health professionals, with regard to COVID-19. Healthcare settings were analyzed in terms of the pandemic nature of the virus, onset and the overall characteristics of disease outbreak. Microbiogists were also used to assess the daily cumulative index of COVID-19. With regard to treatment, chloroquine phosphate and herbal medicines were shown to be promising as supportive treatments to slow COVID-19 transmission, coupled with isolation and quarantine techniques. CONCLUSION: The review indicates that COVID-19 has a high global public health significance due to its high morbidity and mortality rates. Still, there was no specific or effective vaccine or treatment, moreover, the community, including health professionals, have a low perception as regards COVID-19, even though different prevention and control methods have been conducted. Thus, there is a need for awareness creation, alongside further research applied to finding effective vaccine and treatments.


Sujet(s)
COVID-19/prévention et contrôle , COVID-19/thérapie , Services de santé communautaires/tendances , Santé mondiale , Prévention des infections , Pandémies , Santé publique , Humains , Quarantaine
13.
Hum Antibodies ; 29(2): 139-148, 2021.
Article de Anglais | MEDLINE | ID: mdl-32804122

RÉSUMÉ

BACKGROUND: The novel Coronavirus Disease 2019 (COVID-19) is the major public health burden in the world. The morbidity and mortality of the global community due to this disease is dramatically increasing from time to time. OBJECTIVE: This situational analysis is aimed to analyse prevalence and incidence of COVID-19 and to provide clear information about this disease for the scientific community, stakeholders, healthcare practitioners and decision-makers. METHODS: The literatures were identified by searching the key relevant and officially known online databases: medRxiv, Google scholar and PubMed. The online databases contain archives of most English biomedical journals and scientific papers published online from 31 December to 3 April 2020 were included. After the literature search, articles were screened independently by two reviewers for eligibility. RESULTS: The world continents have confirmed a total of 1,202,320 confirmed COVID-19 cases: (51.2%) in Europe, (27.7%) in North America, (17.9%) in Asia, (1.96%) in South America and at less number of confirmed COVID-19 cases in Africa and Australia which was accounted 0.8% and 0.5%, respectively. However, this review showed that there was a significant increase in the confirmed COVID-19 cases by 109,555 in Asia, 8,658 in Africa, 332,866 in North America, 20,269 in South America, 568,894 in Europe, 5,051 in Australia and 1,045,403 in the whole world, with the exception of Antartica, during the review period. The overall results showed that there were 1,098,762 cases and 59,172 deaths recorded during the review period. The result zero number of deaths with COVID-19 was observed in 66 countries. CONCLUSION: The review concluded that COVID-19; SARS-CoV-2 is the major public health burden in the world, the morbidity and mortality of global community is dramatically increasing from time to time. Strong collaboration among all sectors and the design of effective prevention and control strategies which include staying home, social/physical distancing, quarantine, testing of suspected patients, isolation and managing of the confirmed cases. Therefore, all countries should implement five major COVID-19 prevention and control programmes as soon as possible at community level.


Sujet(s)
COVID-19/épidémiologie , Santé mondiale , Pandémies , COVID-19/mortalité , Coûts indirects de la maladie , Humains , Santé publique
14.
PLoS One ; 15(3): e0230187, 2020.
Article de Anglais | MEDLINE | ID: mdl-32163504

RÉSUMÉ

BACKGROUND: Epilepsy is the most common chronic neurologic disorder which affects an estimated 10.5 million children worldwide. Despite the burden, the scarcity of study held in Ethiopia. Hence, the aim of this study was to assess the treatment outcomes of epilepsy and its root causes in children with epilepsy. METHODS: A hospital-based retrospective cohort study was conducted from October 10/2017 up to October 10/2018. A total of 210 study participants who fulfilled the eligibility criteria were included in the study. A structured interviewer-administered questionnaire with a document review was used to collect data. The data were entered into Epi Info version 7.2.1 and analyzed using SPSS version 21. Descriptive statistics were computed. Simple logistic analysis was run (at 95% CI and p-value < 0.05) to identify factors associated with treatment outcome. RESULT: 210 eligible patients with epilepsy were recruited for the study. About half of the respondents were females and the majority was within the age group of 5-10 years. Phenobarbital has been the most frequently prescribed drugs and thirteen percent of patients were in the escalation phase of treatment. Eight percent of the study participants had poor adherence to the treatment regimen. About six percent of the study subjects were suffering from an uncontrolled seizure. Being a female child (AOR = 2. 21; 95%CI: 1.11, 4.41) and excellent adherence to anti-epilepsy treatment (AOR = 4. 51; 95%CI: 1.53, 13.42) were significantly associated with treatment outcome. CONCLUSION: This study revealed that many children were suffering from uncontrolled seizure and escalation therapy is being exercised. Being a female child and adherence to anti-epilepsy treatment were significantly associated with treatment outcome. Therefore, attention should be given to adherence counseling to convey a better treatment outcome.


Sujet(s)
Anticonvulsivants/usage thérapeutique , Épilepsie/traitement médicamenteux , Adolescent , Enfant , Enfant d'âge préscolaire , Femelle , Hôpitaux d'enseignement , Hôpitaux universitaires , Humains , Nourrisson , Mâle , Adhésion au traitement médicamenteux , Phénobarbital/usage thérapeutique , Études rétrospectives , Résultat thérapeutique
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