RÉSUMÉ
The authors report 13 cases of Gayet-Wernicke's encephalopathy observed in 13 patients of a refugee population. 11 presented the classical triad: oculomotor signs, cerebral ataxia and state of confusion and in 2 patients, only 2 symptoms were noted. The etiological factors: chronic alcoholism, malnutrition, uncontrollable vomiting, HIV and tuberculosis were identified. The outcome was evaluated on the basis of the disappearance of symptoms after treatment with 500 mg of thiamine in 7 patients, 1 death and 5 patients progressed toward Korsakoff amnesic syndrome.
Sujet(s)
Encéphalopathie de Gayet-Wernicke/anatomopathologie , Alcoolisme/complications , Confusion/étiologie , Guinée , Infections à VIH/complications , Humains , Réfugiés , Taux de survie , Survivants , Thiamine/usage thérapeutique , Tuberculose/complications , Encéphalopathie de Gayet-Wernicke/traitement médicamenteux , Encéphalopathie de Gayet-Wernicke/mortalité , Encéphalopathie de Gayet-Wernicke/psychologieRÉSUMÉ
This report describes 6 cases of Wilson's disease observed at the University Hospital Center in Conakry, Guinea. Presenting symptoms involved extrapyramidal syndrome in 4 cases, psychomotor epilepsy in 1, and confusional syndrome in 1 case. Diagnosis was based on neuropsychic manifestations, Kayser-Fleicher corneal ring, liver failure, and impaired copper metabolism. Brain CT-scan depicted normal features in 3 cases, symmetric hypodensity of the lenticular nucleus in one, discrete ventricular dilatation of in one a and cortico-subcoetical atrophy in one.
Sujet(s)
Encéphale/anatomopathologie , Dégénérescence hépatolenticulaire/anatomopathologie , Adolescent , Adulte , Affections des ganglions de la base/étiologie , Enfant , Confusion/étiologie , Épilepsie/étiologie , Femelle , Guinée , Dégénérescence hépatolenticulaire/complications , Dégénérescence hépatolenticulaire/diagnostic , Humains , Mâle , TomodensitométrieRÉSUMÉ
This rep o rt describes 6 cases of Wi l s o n 's disease observed at the Unive rsity Hospital Center in Conakry; Guinea. P resenting symptoms invo l ved ex t rapy ramidal syndrome in 4 cases; p s y chomotor ep i l epsy in 1; and confusional syndrome in 1 c a s e. Diagnosis was based on neuro p s y chic manife s t ations; Kayser- F l e i cher corneal ring; liver failure; and impaired copper metabolism. Brain CT-scan depicted normal fe at u res in 3 cases; s y m m e t ric hypodensity of the lenticular nu cleus in one; discrete ve nt ricular dilat ation of in one a and cortico-subcoetical atro p hy in one
