Your browser doesn't support javascript.
loading
Montrer: 20 | 50 | 100
Résultats 1 - 20 de 36
Filtrer
1.
Int J Oral Maxillofac Implants ; 0(0): 1-23, 2024 May 10.
Article de Anglais | MEDLINE | ID: mdl-38728047

RÉSUMÉ

The replacement of missing teeth with implant-supported prostheses has become a standard treatment option with reliable long-term outcomes in various clinical indications.1-6 The implant-supported single crowns, in particular, presented the most favorable outcome with a survival rate of 89.5% to 96% over a 10-year period.5,6 A notable prosthetic maintenance requirement, however, was reported irrespective of the prosthetic material used for the crown construction.1,7 Metal-ceramic restorations have been considered the gold standard when replacing single or multiple missing teeth with implant-supported fixed dental prostheses.8 A systematic review of 4363 metal-ceramic implant-supported single crowns in the anterior and posterior region reported an impressive survival rate of 98.3% over five years.9 Yet, the biologic and prosthetic complications associated with these restorations were substantial with a rate of 13.5%. In the posterior region, a recent systematic review of short-term randomized controlled trials10 reported a survival rate of 99.1% for metal-ceramic implant-supported single crowns. The reported prosthetic complications, mainly ceramic chipping, were also notable with an incidence rate of 7.6%.mIn recent years, the introduction of high-strength all-ceramic materials as well as digitaldesign and manufacturing processes, has allowed faster fabrication of more esthetic and cost effective restorations.11 Zirconia-based fixed dental prostheses on teeth and implants are now increasingly used and show 5-year cumulative survival rates of 89.4 to 100%.12 These restorations are typically made up of a zirconia framework that is veneered with a layer of glass ceramic to impart translucency for enhanced esthetics.13 However, chipping of the ceramic layer has been a lingering issue, shifting the attention toward the use of full anatomic monolithic zirconia restorations.14,15 Replacement of missing teeth with dental implants in posterior ridges with limited bone width can be surgically challenging and the notion of narrow diameter implants has been suggested.16,17 These implants were thought to offer potential advantages in terms of costeffectiveness and surgical morbidity.18,19 The literature, however, remains controversial on treatment outcomes with narrow diameter implants, particularly in posterior sites.19-21 When single tooth replacement with monolithic zirconia implant-supported single crowns in posterior sites are considered, only short to medium-term outcomes are available.22-26 The survival rates and clinical performances reported in these studies were variable. Crown survival rates between 84% and 100% were demonstrated over an observation time of one to three years, while the prosthetic complications were between 0% to 14%. In three studies,22,23,25 standard diameter titanium implants were used in premolar and molar sites to support the single crowns. The remaining two studies by Mühlemann et al. (2020) and Zumstein et al. (2023) reported the one-year and three-year outcomes, respectively, of the same cohort. In these studies, narrow titanium-zirconium (TiZr) implants of 3.3 mm diameter were exclusively utilized in molar sites. The implant and crown survival rates reported at one and three years were 97.4% and 84%, respectively. The lower survival rate observed in the report of Zumstein et al. (2023) resulted from fracture of five implants and the subsequent loss of their respective crowns. Aside from these two reports, no other information on the outcomes of monolithic zirconia single crowns supported by narrow diameter TiZr implants in posterior sites are available. The validity of this treatment, therefore, needs further investigation with well-designed clinical trials. Hence, a randomized controlled trial was undertaken to assess various implant, prosthetic, and patient-reported outcomes of monolithic zirconia single crowns supported by either narrow or standard diameter titanium-zirconium (TiZr) implants in posterior sites. The present report focuses on the one-year prosthetic results.

2.
Clin Oral Implants Res ; 34(8): 802-812, 2023 Aug.
Article de Anglais | MEDLINE | ID: mdl-37300378

RÉSUMÉ

OBJECTIVE: The aims of this clinical trial were to evaluate the radiographic dimensional changes in alveolar ridge and patient-reported outcomes following tooth extraction and alveolar ridge preservation (ARP) using either deproteinized bovine bone mineral (DBBM) with EMD or DBBM alone. METHODS: Participants requiring at least one posterior tooth extraction and ARP were randomly allocated into two treatment groups: ARP using either DBBM with EMD or DBBM alone. Cone-beam computed tomography (CBCT) images were recorded immediately prior to extraction and at 6 months. Changes in alveolar ridge height (ARH) and alveolar ridge width (ARW) at 1, 3, and 5 mm were recorded. RESULTS: A total of 18 participants with 25 preserved sites were evaluated. ARH and ARW changed significantly from baseline to 6 months for both treatment groups but the difference between the groups was not statistically significant over the 6-month follow-up period (ARH: DBBM/EMD 1.26 ± 1.53 mm vs. DBBM 2.26 ± 1.60 mm; ARW-1 DBBM/EMD 1.98 ± 1.80 mm vs. DBBM 2.34 ± 1.89 mm). A significant difference, favoring DBBM with EMD group, was observed in percentage of sites that had less than 1 mm loss in ARH (54.5% sites in DBBM/EMD group vs. 14.3% sites in DBBM alone group). The participants' perception of bruising, bleeding, and pain in the first two postoperative days was significantly in favor of DBBM alone group. CONCLUSIONS: There were no significant differences in radiographic mean measurements of ARH and ARW following ARB with DBBM and EMD or DBBM alone.


Sujet(s)
Résorption alvéolaire , Reconstruction de crête alvéolaire , Humains , Animaux , Bovins , Résorption alvéolaire/imagerie diagnostique , Résorption alvéolaire/prévention et contrôle , Résorption alvéolaire/chirurgie , Antagonistes des récepteurs aux angiotensines , Inhibiteurs de l'enzyme de conversion de l'angiotensine , Processus alvéolaire/imagerie diagnostique , Processus alvéolaire/chirurgie , Extraction dentaire , Reconstruction de crête alvéolaire/méthodes , Alvéole dentaire/chirurgie
3.
Clin Implant Dent Relat Res ; 23(3): 341-360, 2021 Jun.
Article de Anglais | MEDLINE | ID: mdl-33764648

RÉSUMÉ

BACKGROUND: The influence of using different insertion torque values on clinical and radiographic outcomes of implant therapy is unclear in the current literature. The aim of this systematic review and meta-analysis was to evaluate the implant outcomes and complications rates using high insertion torque values compared with those using regular insertion torque value levels. METHODS: Randomized controlled trials (RCTs), nonrandomized controlled clinical trials (NRCCTs), prospective and retrospective cohorts were searched for in electronic databases and complemented by hand searching relevant dental journals. The risk of bias was assessed using the Cochrane Collaboration's Risk of Bias tool for randomized and nonrandomized studies. Data were analyzed using a statistical software. RESULTS: A total of 718 studies were identified, of which, nine studies were included with 1229 dental implants in 684 participants. The meta-analysis of RCTs showed that the overall implant failure rate was not notably in favor of any insertion torque value and the difference between the two groups was not statistically significant (risk ratio 0.85; 95% confidence interval 0.07-10.52; P = 0.90). None of the RCTs was registered. The secondary analyses of non-RCTs did not either show any statistically significant difference. Overall meta-analysis did not show any significant differences in peri-implant marginal bone loss or biological/technical complications between high (≥50 Ncm) and regular insertion torque (<50 Ncm). CONCLUSIONS: There is insufficient evidence to support the use of high or regular insertion torque even with immediate implant restoration/loading. The short-term implant failure rates, changes in marginal bone level and complication rates were comparable when high or regular insertion torques were used for implant placement. The wide confidence interval indicated that results cannot be interpreted with clinically meaningful benefit for using either high or regular insertion torque.


Sujet(s)
Implants dentaires , Pose immédiate d'implant dentaire , Pose d'implant dentaire endo-osseux/effets indésirables , Implants dentaires/effets indésirables , Échec de restauration dentaire , Humains , Moment de torsion
4.
J Am Dent Assoc ; 152(1): 16-24, 2021 01.
Article de Anglais | MEDLINE | ID: mdl-33250171

RÉSUMÉ

BACKGROUND: COVID-19 continues to affect the dental community worldwide. The authors conducted a cross-sectional electronic study using a multisite survey to examine dentists' knowledge, attitudes, and professional behavior toward COVID-19 and the affect on their livelihood. METHODS: A questionnaire was circulated via e-mail and social media platforms to dentists in North America, Europe, Eastern Mediterranean, and Western Pacific regions. It covered demographic characteristics and questions about the COVID-19 outbreak related to dentists' levels of comfort for preventive and safety measures, provision of treatment, affect on work, and financial implications. Responses were tabulated and analyzed by means of χ2 or Fisher exact test. Mann-Whitney and Kruskal-Wallis tests were used to compare means. P < .05 was considered significant. RESULTS: A total of 1,251 dentists responded. General dentists represented 63.9% of the respondents and 62.5% worked in private practice. The global score for level of comfort with the preventive measures and provisions of treatment during the COVID-19 pandemic was low (14 of 30), and differences between regions were significant (P < .01); dentists working in private practice and general dental practitioners were less comfortable (P < .01). CONCLUSIONS AND PRACTICAL IMPLICATIONS: The respondents reported a lack of preparedness to confront a highly infectious respiratory disease. A new level of protective armamentarium in the dental operatory and updated operational guidance and policies are required, necessitating educators and regulators to ensure the delivery of knowledge and skills to oral health care providers. Dentists need to address the sustainability of their practices and have a robust business plan.


Sujet(s)
COVID-19 , Modèles de pratique odontologique , Attitude du personnel soignant , Études transversales , Dentistes , Connaissances, attitudes et pratiques en santé , Humains , Amérique du Nord , Pandémies , Rôle professionnel , SARS-CoV-2 , Enquêtes et questionnaires
5.
J Oral Maxillofac Surg ; 78(7): 1071-1077, 2020 07.
Article de Anglais | MEDLINE | ID: mdl-32277937

RÉSUMÉ

PURPOSE: We aimed to investigate whether cone-beam computed tomography (CBCT) alters the treatment decision for impacted mandibular third molar (M3M) surgery when the third molars show proximity to the inferior alveolar canal (IAC) on panoramic radiography (OPG) and to examine surgeons' confidence in the various treatment options. METHODS: We performed a retrospective study evaluating a series of randomized OPG and CBCT images and answering a set of questions regarding impacted M3Ms. The anatomic risk factors studied included the proximity of M3M roots to the IAC, vertical relationship between the M3M and the IAC, and interruption of the IAC cortex by M3M roots. The primary outcome variable was the treatment decision of whether to observe, extract under local anesthesia, extract under general anesthesia, or perform coronectomy. The secondary outcome variable was confidence in the proposed treatment plan. The χ2 test was used to compare proportions and to test the differences in the treatment plan according to the studied independent variables. Binary logistic regression was used to determine the effect of anatomic factors. P < .05 was considered statistically significant. RESULTS: The study sample consisted of 132 impacted M3Ms in 71 patients. No significant differences in the proposed treatment plan were found when the imaging modalities (OPG and CBCT) were compared (P > .05). Examination of CBCT enabled detection of anatomic risk factors (P < .001). Binary logistic regression showed the absence of IAC cortex interruption to be the most significant determinant toward planning for extraction on OPG (odds ratio, 3.1; P < .005) and on CBCT (odds ratio, 5.0; P < .001). Surgeons were more confident when planning for extraction (P < .001). CONCLUSIONS: The use of CBCT provides a better understanding of the anatomic relationship between M3M roots and the IAC. However, experienced surgeons dealing with impacted M3Ms with evidence of proximity to the IAC on OPG can decide on the treatment modality without CBCT.


Sujet(s)
Dent de sagesse , Dent enclavée , Tomodensitométrie à faisceau conique , Humains , Mandibule , Nerf mandibulaire , Radiographie panoramique , Études rétrospectives
6.
Med. oral patol. oral cir. bucal (Internet) ; 24(4): e545-e554, jul. 2019. ilus, tab
Article de Anglais | IBECS | ID: ibc-185669

RÉSUMÉ

Background: Mandibular sagittal split osteotomy (MSSO) may incur unfavorable split and sensorineural injuries. Knowledge of the anatomic location of the mandibular canal (MC) and bone thickness in the region of interest for MSSO, and the possible variations by age and gender can assist in avoiding such complications. Purpose: To study the location of the MC and bone thickness in the region of MSSO by cone-beam computed tomography (CBCT) radiographs and to evaluate the possible variations by age and gender in a Jordanian population. Material and Methods: This retrospective radio-anatomical study examined all CBCT radiographs for patients treated over three years at the University of Jordan Hospital, Amman, Jordan. Distances from the MC to the cortical external surfaces and MC diameter (MCD) were measured by a reliable observer at three predetermined regions for MSSO: region (A) [mandibular foramen area], region (B) [mandibular angle area] and region (C) [directly mesial to the second molar]. Gender and age differences in all measurements were then compared using non-parametric Mann-Whitney U test. Results: The final study radiographs comprised a total of 202 CBCT belonged to a cohort of 202 subjects; 91 males (45.1%) and 111 (54.9%) females, with mean age (± SD) of 42.94 ± 18.54 years (range 18-90 years). Whereas only the bone thickness superior, buccal and inferior to MC in regions (B) and (C), and MCD in the three regions exhibited significant (p < 0.05) gender differences, all measured distances exhibited statistically significant (p < 0.05) differences between young and adult patients. Conclusion: The location of MC and bone thickness in the region of MSSO were significantly variable according to age, but exhibited sexual diamorphism only in regions (B) and (C). This fundamental knowledge should be considered during MSSO planning


No disponible


Sujet(s)
Humains , Mâle , Femelle , Adolescent , Jeune adulte , Adulte , Adulte d'âge moyen , Sujet âgé , Sujet âgé de 80 ans ou plus , Tomodensitométrie à faisceau conique , Mandibule , Molaire , Ostéotomie , Études rétrospectives
7.
Eur J Oral Sci ; 126(2): 110-117, 2018 04.
Article de Anglais | MEDLINE | ID: mdl-29450917

RÉSUMÉ

The aim of this study was to assess the influence of patients' and surgical variables on the onset and duration of action of local anesthesia (LA) in mandibular third-molar (M3) surgery. Patients scheduled for mandibular M3 surgery were considered for inclusion in this prospective cohort study. Patients' and surgical variables were recorded. Two per cent (2%) lidocaine with 1:100,000 epinephrine was used to block the nerves for extraction of mandibular M3. Then, the onset of action and duration of LA were monitored. Univariate analysis and multivariate regression analysis were used to analyze the data. The final cohort included 88 subjects (32 men and 56 women; mean age ± SD = 29.3 ± 12.3 yr). With univariate analysis, age, gender, body mass index (BMI), smoking quantity and duration, operation time, and 'volume of local anesthetic needed' significantly influenced the onset of action and duration of LA. Multivariate regression revealed that age and smoking quantity were the only statistically significant predictors of the onset of action of LA, whereas age, smoking quantity, and 'volume of local anesthetic needed' were the only statistically significant predictors of duration of LA. Further studies are recommended to uncover other predictors of the onset of action and duration of LA.


Sujet(s)
Anesthésie dentaire , Anesthésie locale , Fumer des cigarettes , Dent de sagesse/chirurgie , Adolescent , Adulte , Sujet âgé , Analyse de variance , Épinéphrine , Femelle , Humains , Lidocaïne , Mâle , Mandibule , Adulte d'âge moyen , Études prospectives , Facteurs sexuels , Facteurs temps , Jeune adulte
8.
Int. j. morphol ; 34(1): 310-319, Mar. 2016. ilus
Article de Anglais | LILACS | ID: lil-780511

RÉSUMÉ

Accurate information regarding the vertical location and appearance of the mental foramen, and the presence of accessory foramina, can have clinical significance, such as reducing complications that may occur during many oral surgical procedures involving the mental area. Geographic variations were reported in these variables. The aim was to evaluate the above-mentioned variables in an Iraqi sample. Five hundred eighteen panoramic radiographs of a random Iraqi sample (257 males, 261 females, average age= 46.5 years) were evaluated with regard to the above-mentioned variables, as well as the symmetry of the foramen regarding these variables. The area below the apices of mandibular premolars, and the continuous type were the most frequent vertical location and appearance of the mental foramen, respectively. Age advancement was found to be associated with an increase in the frequency of more inferior positioning and continuous appearance. The vertical position and appearance were asymmetrical in 16.2 % and 20.1 % of cases, respectively. Symmetry in the vertical location was statistically significant between sexes (P= 0.035), and young and old ages (P= 0.000). Symmetry in the appearance was found statistically significant (P= 0.025) only between the two age groups. Accessory foramina were recorded in 7.3 % of cases. The most common vertical location and appearance of the mental foramen on panoramic radiographs in this group are below the apices of mandibular premolars, and continuous type, respectively. This is in consistence with the findings of previous studies on other populations. The mental foramen usually has symmetrical vertical location and appearance. Accessory foramina are recorded in a percentage lower than that recently reported in some regional countries.


La información precisa acerca de la localización vertical, apariencia del foramen mental y la presencia de forámenes accesorios, puede tener importancia clínica, como la reducción de las complicaciones que pueden ocurrir durante muchos procedimientos quirúrgicos orales relacionados con el mentón. Las variaciones geográficas fueron reportadas en estas variables. El objetivo fue evaluar las variables anteriormente mencionadas en una muestra iraquí. Fueron evaluadas 518 radiografías panorámicas de una muestra aleatoria de Irak (257 varones, 261 mujeres, edad media = 46,5 años) con respecto a las variables antes mencionadas, así como la simetría del foramen con respecto a estas variables. El área por debajo de los ápices de los premolares mandibulares y el tipo continuo, fueron la localización vertical y apariencia del foramen mental más frecuentes, respectivamente. La edad avanzada se asoció con un aumento en la frecuencia de posicionamiento más inferior y de apariencia continua. La localización vertical y la apariencia fueron asimétricas en 16,2 % y 20,1 % de los casos, respectivamente. La simetría en la localización vertical fue estadísticamente significativa entre sexos (p= 0,035), y entre jóvenes y viejos (P= 0,000). La simetría en apariencia sólo fue estadísticamente significativa (p= 0,025) entre los dos grupos de edad. Se registró presencia de forámenes accesorios en un 7,3 % de los casos. La localización vertical del foramen mental más común en las radiografías panorámicas de este grupo están por debajo de los ápices de los premolares mandibulares, y respecto a la apariencia, el tipo continuo fue el más común. Esto está en coherencia con los resultados de estudios anteriores en otras poblaciones. Los forámenes mentales tienen una localización vertical y apariencia que suelen ser simétricas. Los forámenes accesorios se registran en un porcentaje inferior al informado recientemente en algunos países de la región.


Sujet(s)
Humains , Mâle , Femelle , Adolescent , Adulte , Adulte d'âge moyen , Sujet âgé , Variation anatomique , Mandibule/anatomie et histologie , Mandibule/imagerie diagnostique , Iraq , Radiographie panoramique , Répartition par sexe
10.
Saudi Med J ; 36(3): 310-5, 2015 Mar.
Article de Anglais | MEDLINE | ID: mdl-25737173

RÉSUMÉ

OBJECTIVES: To identify potential risk factors such as smoking, cardiovascular diseases (CVD), denture wearing, and consuming vitamin rich foods, and its relation to the development of sublingual varices (SLV). METHODS: This cross-sectional observational study was conducted on patients who attended the Department of Dentistry at The University of Jordan Hospital, Amman, Jordan between February and May 2013. Clinical examinations and inspections of 391 patients (203 males and 188 females), 13-74 years of age were conducted to determine the presence of SLV. Sublingual varices were classified into 2 categories: grade 0 (few or none visible), and grade one (moderate or severe). Frequency distributions of both SLV and risk factors were obtained. Multiple logistic regression analysis and Chi-square test were used to analyze the influence of individual risk factors on the incidence of SLV. RESULTS: There were 88 subjects (22.5%) who had SLV. In the multivariate logistic regression model, SLV were significantly associated with age (odds ratio [OR]: 2.27, p=0.008) with highest occurrences in the eighth decade of life, gender (OR: 2.74, p=0.001), smoking (OR: 2.93, p=0.002), denture wearing (OR: 2.03, p=0.044), and CVD (OR: 4.01, p=0.00). CONCLUSION: The presence of SLV could be indicative of some potential risk factors including old age, female gender, and denture wearing, and may alert the dental clinician to recognize underlying systemic conditions, particularly CVD.


Sujet(s)
Maladies cardiovasculaires/complications , Appareils de prothèse dentaire/effets indésirables , Aliments , Fumer , Maladies de la langue/étiologie , Varices/étiologie , Vitamines/administration et posologie , Adulte , Sujet âgé , Enfant , Humains , Nourrisson , Adulte d'âge moyen , Jeune adulte
11.
Int. j. morphol ; 33(1): 149-157, Mar. 2015. ilus
Article de Anglais | LILACS | ID: lil-743778

RÉSUMÉ

Accurate information regarding the horizontal location and shape of the mental foramen can have clinical significance, such as reducing complications that may occur during maxillofacial surgical procedures involving the mental area. Geographic variations were reported in these variables. The aim was to study the horizontal position and shape of the mental foramen, as seen on panoramic radiographs of an Iraqi sample, to assess difference in these variables between sexes and age groups, and to assess symmetry of the mental foramen. 518 panoramic radiographs of a random Iraqi sample (257 males, 261 females, average age=46.5 years) were evaluated with regard to the horizontal location, shape and symmetry of the mental foramina. The area between the long axes of the two mandibular premolars, and the round type were the most frequent horizontal location and shape of mental foramen, respectively. Age advancement was found to be associated with an increase in the frequency of more posterior positioning and irregular shape. The horizontal position and shape were asymmetrical in 21.6% and 31.6% of cases, respectively. The Symmetry in horizontal location and shape of mental foramina were found statistically significant between sexes (P=0.041), and between young and old age groups (P=0.001), respectively. The most common horizontal location and shape of the mental foramen on panoramic radiographs in this group are between the two premolars, and the round type, respectively. This is in consistence with the findings of previous studies on other populations. The mental foramina have usually symmetrical horizontal locations and shapes.


Información precisa sobre la ubicación horizontal y forma del foramen mental puede tener importancia clínica en la reducción de complicaciones durante procedimientos quirúrgicos maxilofaciales que involucran el área mental. Fueron reportadas variaciones geográficas en relación a estas variables. El objetivo fue estudiar la posición horizontal y forma del foramen mental, a partir de 518 radiografías panorámicas de una muestra aleatoria en sujetos de Irak (257 varones, 261 mujeres; edad media= 46,5 años), quienes fueron evaluados con respecto a la posición horizontal, forma y la simetría de los forámenes mentales. En individuos de edad avanzada se encontró una asociación con un aumento en la frecuencia de un posicionamiento posterior y con forma irregular. La posición horizontal y forma del foramen fueron asimétricos en 21,6% y 31,6% de los casos, respectivamente. La diferencia hallada en relación a la simetría en posición horizontal y forma de los forámenes mentales fue estadísticamente significativa entre sexos (p=0,041), y entre los grupos de edad jóvenes y mayores (P=0,001), respectivamente. Se encontró con mayor frecuencia la posición horizontal entre los ejes longitudinales de los dos premolares mandibulares, y la forma circular, en relación a la posición antero-posterior y forma del foramen, respectivamente. Estos fueron resultados similares a estudios anteriores sobre otras poblaciones. Los forámenes mentales son simétricos, respecto a su ubicación horizontal y su forma.


Sujet(s)
Humains , Mâle , Femelle , Adolescent , Adulte , Adulte d'âge moyen , Sujet âgé , Mandibule/anatomie et histologie , Mandibule/imagerie diagnostique , Radiographie panoramique , Distribution de L'âge et du Sexe , Iraq , Caractéristiques de l'habitat
12.
PLoS Genet ; 9(2): e1003302, 2013.
Article de Anglais | MEDLINE | ID: mdl-23468644

RÉSUMÉ

Enamel-renal syndrome (ERS) is an autosomal recessive disorder characterized by severe enamel hypoplasia, failed tooth eruption, intrapulpal calcifications, enlarged gingiva, and nephrocalcinosis. Recently, mutations in FAM20A were reported to cause amelogenesis imperfecta and gingival fibromatosis syndrome (AIGFS), which closely resembles ERS except for the renal calcifications. We characterized three families with AIGFS and identified, in each case, recessive FAM20A mutations: family 1 (c.992G>A; g.63853G>A; p.Gly331Asp), family 2 (c.720-2A>G; g.62232A>G; p.Gln241_Arg271del), and family 3 (c.406C>T; g.50213C>T; p.Arg136* and c.1432C>T; g.68284C>T; p.Arg478*). Significantly, a kidney ultrasound of the family 2 proband revealed nephrocalcinosis, revising the diagnosis from AIGFS to ERS. By characterizing teeth extracted from the family 3 proband, we demonstrated that FAM20A(-/-) molars lacked true enamel, showed extensive crown and root resorption, hypercementosis, and partial replacement of resorbed mineral with bone or coalesced mineral spheres. Supported by the observation of severe ectopic calcifications in the kidneys of Fam20a null mice, we conclude that FAM20A, which has a kinase homology domain and localizes to the Golgi, is a putative Golgi kinase that plays a significant role in the regulation of biomineralization processes, and that mutations in FAM20A cause both AIGFS and ERS.


Sujet(s)
Amélogenèse imparfaite , Protéines de l'émail dentaire , Fibromatose gingivale , Néphrocalcinose , Amélogenèse imparfaite/diagnostic , Amélogenèse imparfaite/génétique , Amélogenèse imparfaite/métabolisme , Amélogenèse imparfaite/anatomopathologie , Animaux , Calcinose/diagnostic , Calcinose/génétique , Calcinose/métabolisme , Émail dentaire/métabolisme , Émail dentaire/anatomopathologie , Protéines de l'émail dentaire/déficit , Protéines de l'émail dentaire/génétique , Protéines de l'émail dentaire/métabolisme , Fibromatose gingivale/diagnostic , Fibromatose gingivale/génétique , Fibromatose gingivale/anatomopathologie , Appareil de Golgi/métabolisme , Appareil de Golgi/anatomopathologie , Humains , Rein/métabolisme , Rein/physiopathologie , Souris , Mutation , Néphrocalcinose/diagnostic , Néphrocalcinose/génétique , Néphrocalcinose/métabolisme , Phosphotransferases/génétique , Phosphotransferases/métabolisme
13.
Oral Health Prev Dent ; 11(2): 105-12, 2013.
Article de Anglais | MEDLINE | ID: mdl-23534038

RÉSUMÉ

PURPOSE: To assess the prevalence and related factors of traumatic dental injuries (TDI) among 12-year-old Jordanian schoolchildren. MATERIALS AND METHODS: For this cross-sectional study among schoolchildren, a sample of 2560 schoolchildren (1209 boys, 1351 girls) aged 12 years were randomly selected. The epidemiological classification adopted by the World Health Organization (WHO) and modified by Andreasen et al was used to record TDI on incisors. RESULTS: Of the children examined, 5.5% showed TDI. The difference in prevalence between boys and girls was statistically significant (P < 0.01). Maxillary central incisors were the most affected and the most common type of crown injury was enamel/dentin fracture. The relationship between dental injuries and geographic location, area, and socioeconomic indicators was not statistically significant. Most of the TDI occurred at home, followed by school; the most frequent cause was falls. No statistically significant association was found between TDI and dental caries experience (P > 0.05). There was a tendency for boys (P < 0.01), children with an incisal overjet > 3 mm (P < 0.01) and incompetent lip closure (P < 0.001) to have experienced dental injuries. Treatment need due to dental injuries was very high. CONCLUSION: The prevalence of traumatic injuries to permanent incisors in 12-year-old Jordanian schoolchildren was relatively low. TDI was associated with gender, overjet and lip competence, but was not influenced by dental caries experience. There was a great unmet treatment need.


Sujet(s)
Incisive/traumatismes , Évaluation des besoins/statistiques et données numériques , Chutes accidentelles/statistiques et données numériques , Accidents domestiques/statistiques et données numériques , Traumatismes sportifs/épidémiologie , Enfant , Études transversales , Indice DCAO , Émail dentaire/traumatismes , Dentine/traumatismes , Femelle , Humains , Jordanie/épidémiologie , Lèvre/anatomopathologie , Mâle , Surocclusion/épidémiologie , Prévalence , Facteurs de risque , Santé en zone rurale/statistiques et données numériques , Facteurs sexuels , Classe sociale , Couronne dentaire/traumatismes , Fractures dentaires/épidémiologie , Santé en zone urbaine/statistiques et données numériques , Populations vulnérables/statistiques et données numériques
14.
Br J Oral Maxillofac Surg ; 50(3): 239-43, 2012 Apr.
Article de Anglais | MEDLINE | ID: mdl-21612850

RÉSUMÉ

The objective of this prospective study was to estimate the incidence of early loss of dental implants and the potential risk factors. The predictive variables were classified as being patient, implant, anatomical, or operation-specific. The outcome variable was early failure of the implant. The significance of differences was assessed using bivariate analyses, and then a multivariate logistic regression model to identify independent predictors for early loss of implants. A total of 169 patients, 116 women and 53 men, mean age 47 (range 16-80) years, had 399 implants inserted. Fifteen implants were lost in 14 patients (8%). The early loss of dental implants was significantly associated with width of keratinised gingiva (p=0.008), the use polyglactin sutures (p=0.048), and the use of narrow implants (p=0.035). Multivariate logistic regression analysis established the significance of narrow keratinised gingiva (OR=4.7, p=0.005) and the use of polyglactin sutures (OR=3.8, p=0.042), which we conclude are probably the strongest predictors of early failure of implants.


Sujet(s)
Implants dentaires , Échec de restauration dentaire , Adolescent , Adulte , Sujet âgé , Sujet âgé de 80 ans ou plus , Maladie chronique , Pose d'implant dentaire endo-osseux/méthodes , Conception de prothèse dentaire , Femelle , Gencive/anatomopathologie , Humains , Complications peropératoires , Mâle , Adulte d'âge moyen , Ostéo-intégration/physiologie , Polyglactine 910/composition chimique , Études prospectives , Facteurs de risque , Soie/composition chimique , Fumer , Lambeaux chirurgicaux , Matériaux de suture , Résultat thérapeutique , Jeune adulte
15.
Eur J Oral Implantol ; 4(1): 31-8, 2011.
Article de Anglais | MEDLINE | ID: mdl-21594217

RÉSUMÉ

PURPOSE: To compare the efficacy of three different antibiotic regimens in reducing early dental implant failure. MATERIALS AND METHODS: In a controlled clinical trial, 270 consecutively treated patients were allocated to three antibiotic groups, alternatively, according to order of participation in the trial: Group A (2 g amoxicillin single preoperative dose), Group B (single preoperative 2 g amoxicillin followed by 500 mg three times daily for 5 days) and Group C (postoperative amoxicillin with clavulanic acid 625 mg three times daily for 5 days). Outcomes were pain, wound infection, dehiscence, adverse events possibly related to antibiotics and early implant failure. The patients were followed postoperatively at 1 week, 1 month and at the beginning of the prosthetic stage. Chi-square test and ANOVA test were used to examine differences. RESULTS: In total, 240 patients were adherent to the trial protocol: Group A, 73 patients (210 implants); Group B, 79 patients (266 implants); and Group C, 88 patients (290 implants). Patients experiencing early implant failure: 12 in Group A (16.4%), 11 in Group B (13.9%) and 13 in Group C (14.8%). No statistically significant differences were observed for any of the outcome measures between the three groups. CONCLUSIONS: It may not be necessary to provide postoperative antibiotics in patients undergoing dental implant placement, however, these preliminary findings need to be confirmed by large multicentre clinical trials.


Sujet(s)
Antibioprophylaxie/méthodes , Pose d'implant dentaire endo-osseux , Échec de restauration dentaire , Adulte , Amoxicilline/administration et posologie , Association amoxicilline-clavulanate de potassium/administration et posologie , Analyse de variance , Antibactériens/administration et posologie , Loi du khi-deux , Acide clavulanique/administration et posologie , Pose d'implant dentaire endo-osseux/effets indésirables , Association médicamenteuse , Femelle , Humains , Mâle , Adulte d'âge moyen , Douleur postopératoire , Soins postopératoires , Soins préopératoires , Lâchage de suture , Infection de plaie opératoire
16.
Saudi Dent J ; 23(2): 107-9, 2011 Apr.
Article de Anglais | MEDLINE | ID: mdl-24151418

RÉSUMÉ

Patients with primary hyperparathyroidism (brown tumor) are usually asymptomatic and clinical presentation of the tumor in the jaws is rarely the first sign of the disease. We report a 45-year-old female patient who presented with a mandibular swelling as the first sign of the disease.

17.
Ann R Coll Surg Engl ; 92(6): 489-94, 2010 Sep.
Article de Anglais | MEDLINE | ID: mdl-20522306

RÉSUMÉ

INTRODUCTION: We describe our experience with oncology patients on a frequent dosing schedule of intravenous (i.v.) bisphosphonates at the Jordan University Hospital (JUH). PATIENTS AND METHODS: Patients treated by i.v. bisphosphonates in the medical oncology unit at the JUH were examined for bisphosphonate-related osteonecrosis of the jaws (BRONJ). Diagnosis was made according to the guidelines of the American Association of Oral and Maxillofacial Surgeons (AAOMS) original position paper. RESULTS: Of the 41 patients, four developed BRONJ, two in maxilla, one in mandible and one bimaxillary. Patients with BRONJ were older; mean age was 69.3 +/- 3.1 years compared to 62.8 +/- 12.5 years (P = 0.022). Dental co-morbidities were more commonly present in patients with the disease (P = 0.038). Patients who developed BRONJ were on treatment for a longer duration of time; the mean duration of treatment was 23.5 +/- 8.4 months compared to 11.9 +/- 13.4 months (P = 0.10). CONCLUSIONS: The results of this case series demonstrated that age and poor oral health status are significant risk factors of BRONJ for oncology patients on long-term frequent dosing schedule of i.v. bisphosphonates.


Sujet(s)
Agents de maintien de la densité osseuse/effets indésirables , Diphosphonates/effets indésirables , Maladies de la mâchoire/induit chimiquement , Ostéonécrose/induit chimiquement , Adulte , Facteurs âges , Sujet âgé , Sujet âgé de 80 ans ou plus , Agents de maintien de la densité osseuse/administration et posologie , Diphosphonates/administration et posologie , Calendrier d'administration des médicaments , Femelle , Humains , Injections veineuses , Mâle , Adulte d'âge moyen , Santé buccodentaire , Facteurs de risque , Tomodensitométrie
18.
Saudi Med J ; 31(4): 369-73, 2010 Apr.
Article de Anglais | MEDLINE | ID: mdl-20383412

RÉSUMÉ

OBJECTIVE: To estimate active maximum mouth opening (AMMO) in a Jordanian subpopulation and to study associated factors and relationship to patient's dental conditions. METHODS: This cross-sectional study was conducted on 496 patients aged 15-80 years at the University of Jordan Hospital, Amman, Jordan between October 2008 and March 2009. The AMMO was measured as maximum distance between incisal edges of upper and lower central incisors. Descriptive statistics and uni- and multivariate analyses were used to determine factors affecting AMMO. RESULTS: Mean AMMO +/- standard deviation was 42.9 +/- 5.7 mm. The AMMO varied significantly between men (45.3 +/- 5.7 mm) and women (41.5 +/- 5.3 mm), decreased with age, and correlated positively with body height and weight, but no relation was found with body mass index and temporomandibular joint complaints. The relationship of AMMO to patient's dental conditions revealed a negative correlation with number of missing teeth, but not with number of decayed or restored teeth. Subjects who had present third molars had wider AMMO compared to subjects with extracted, impacted, or congenitally missing third molars. Multivariate regression analysis revealed gender, age, and weight to be the only independent predictors of AMMO. CONCLUSION: In this population, AMMO is influenced by gender, age, and weight of patients and was generally narrower than that reported in European populations. Wide AMMO was associated with less risk of tooth loss and preservation of third molars.


Sujet(s)
Arthrométrie , Diagnostic buccal/méthodes , Dépistage de masse/méthodes , Troubles de l'articulation temporomandibulaire/prévention et contrôle , Adolescent , Adulte , Sujet âgé , Sujet âgé de 80 ans ou plus , Études transversales , Femelle , Humains , Jordanie , Mâle , Adulte d'âge moyen , Analyse multifactorielle , Amplitude articulaire
19.
Clin Implant Dent Relat Res ; 12(3): 249-53, 2010 Sep.
Article de Anglais | MEDLINE | ID: mdl-19438963

RÉSUMÉ

BACKGROUND: Cholesterol granuloma (CG) is a foreign-body reaction to the deposition of cholesterol crystals. Its occurrence in the paranasal sinuses is very rare. PURPOSE: This report describes a new case of maxillary sinus CG discovered incidentally during sinus-floor augmentation for dental implant placement in a 60-year-old female patient. MATERIALS AND METHODS: The preoperative clinical and radiological examinations revealed a normal maxillary antrum with no evidence of sinus pathology. After lateral osteotomy, a dark-green, viscous soft tissue mass appeared through the thin mucous membrane inside the sinus. Enucleation and curettage of the sinus contents including the sinus membrane were performed for histopathologic analysis. The augmentation and implant placement procedures were postponed. RESULTS: Histopathologic analysis showed several fragments of granulation tissue containing diffuse cholesterol clefts surrounded by mixed chronic inflammatory cell infiltrate including plasma cells and lymphocytes. These features were compatible with the diagnosis of CG. The patient was followed up for 3 months after the first procedure, and a second attempt of sinus augmentation and dental implant insertion was then carried out. The inserted dental implants were followed up for 6 months without any complications. CONCLUSIONS: CG of maxillary sinus can be an incidental finding. For this reason, the final diagnosis can only be achieved after examination of the material under the microscope.


Sujet(s)
Reconstruction de crête alvéolaire/méthodes , Cholestérol/effets indésirables , Réaction à corps étranger/étiologie , Granulome/étiologie , Sinus maxillaire/anatomopathologie , Maladies des sinus/étiologie , Pose d'implant dentaire endo-osseux/méthodes , Femelle , Réaction à corps étranger/anatomopathologie , Granulome/anatomopathologie , Granulome/chirurgie , Humains , Résultats fortuits , Sinus maxillaire/chirurgie , Adulte d'âge moyen , Procédures de chirurgie préprothétique en odontologie/méthodes , Maladies des sinus/anatomopathologie , Maladies des sinus/chirurgie , Résultat thérapeutique
20.
Med Princ Pract ; 19(1): 28-32, 2010.
Article de Anglais | MEDLINE | ID: mdl-19996616

RÉSUMÉ

OBJECTIVE: The objective of this study was to estimate the frequency of postoperative lingual nerve (LN) impairment after the surgical removal of mandibular third molars (M3) and to identify potential risk indicators. SUBJECTS AND METHODS: A prospective cohort study involving 321 subjects who had 443 mandibular M3 surgically extracted at the University Hospital, Amman, Jordan. Predictor variables were categorized as patient-, anatomy- and operation-specific. The outcome variable was the presence or absence of LN impairment. Bivariate and multivariate analyses were performed to identify independent predictors. RESULTS: The prevalence of temporary LN hypoesthesia was 2.5% and all 11 cases resolved within 6 months. Factors that predicted LN injury by univariate analysis were horizontal and mesioangular tooth angulation, bone removal, tooth sectioning, longer operations, lingual flap retraction and bleeding into the socket. In the multivariate logistic regression model, lingual flap retraction (p = 0.002, OR = 26.790) and bleeding into the socket (p = 0.044, OR = 4.918) were the independent predictors. CONCLUSION: Operative variables were the main predictors of temporary LN damage.


Sujet(s)
Hypoesthésie/étiologie , Lésions du nerf lingual , Dent de sagesse/innervation , Dent de sagesse/chirurgie , Extraction dentaire/effets indésirables , Adolescent , Adulte , Sujet âgé , Femelle , Humains , Maladie iatrogène , Mâle , Adulte d'âge moyen , Études prospectives , Extraction dentaire/méthodes , Jeune adulte
SÉLECTION CITATIONS
DÉTAIL DE RECHERCHE
...