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1.
J. nurs. health ; 14(1): 1424268, abr.2024.
Article de Portugais | LILACS, BDENF - Infirmière | ID: biblio-1554251

RÉSUMÉ

Objetivo: descrever a capacidade de cuidado familiar em paliação na atenção domiciliar. Métodos: estudo descritivo desenvolvido em São Luís, Maranhão, com 112 cuidadores familiares de pacientes em paliação. A coleta de dados foi realizada de fevereiro a maio de 2021 utilizando instrumento contendo variáveis sociodemográficas e Escala Capacidade paraCuidar em Paliativos com análise por Escala Likert. Resultados: maioria dos cuidadores são mulheres (91,07%), adultas (83,03%), pardas (62,5%), solteiras (50%) com ensino médio (51,79%). A análise da escala revelou 34,82% dos cuidadores precisam trabalhar as informações sobre a doença do familiar e aprender lidar com situações difícil,64,29 % indicam a carência em relação ao medo e impotência, e82,14% necessitam atenção quanto a capacidade física e psicológica para cuidar. Conclusão: a capacidade melhor avaliada é a de dimensão prática. As dimensões, emocional e autocuidado, necessitam de intervenção profissional para melhora do ato de cuidar.


Objective: to describe the capacity for family care in palliation in home care. Methods:descriptive study developed in São Luís, Maranhão, with 112 family caregivers of patients undergoing palliation. Data collection was carried out from February to May 2021 using an instrument containing sociodemographic variables and the Capacity for Palliative Care Scale with analysis using Likert Scale. Results: most caregivers are women (91.07%), adults (83.03%), mixed race (62.5%), single (50%) and with high school education (51.79%). Analysis of the scale revealed that 34.82% of caregivers need to work on the information about the family member's illness and learn to deal with difficult situations, 64.29% indicate a need for fear and impotence, and 82.14% need attention their physical and psychological capacity to care. Conclusion:the best evaluated ability is the practical dimension. The emotional and self-care dimensions require professional intervention to improve the act of caring.


Objetivo:describir la capacidad de cuidado familiar en paliativo domiciliarios. Métodos:estudio descriptivo desarrollado en São Luís, Maranhão, 112 cuidadores familiares de pacientes en paliación. La recolección de datos se realizó de febrero a mayo de 2021 mediante un instrumento que contiene variables sociodemográficas y la Escala de Capacidad en Cuidados Paliativos con análisis mediante Escala Likert. Resultados:la mayoría de los cuidadores son mujeres (91,07%), adultos (83,03%), mestizos (62,5%), solteros (50%) y estudios secundarios (51,79%). El análisis de la escala reveló que el 34,82% de los cuidadores necesita trabajar la información sobre la enfermedad del familiar y aprender a lidiar con situaciones difíciles, el 64,29% indica necesidad de miedo e impotencia y el 82,14% necesita atención al físico y capacidad psicológica para cuidar. Conclusión:la habilidad mejor evaluada es la dimensión práctica. La dimensión emocional y de autocuidado requieren intervención profesional para mejorar el acto decuidar.


Sujet(s)
Aidants , Soins palliatifs , Soins à domicile
2.
Mar Pollut Bull ; 194(Pt A): 115342, 2023 Sep.
Article de Anglais | MEDLINE | ID: mdl-37634349

RÉSUMÉ

Drill cuttings comprise a mixture of rocks generated during drilling activities of exploration and production of oil and gas. These residues' properties are variable, depending on several drilling parameters and drilled rock composition. Many scientific studies have been published regarding the characterization of these residues. Articles summarizing these residues' characteristics and toxicity data are poorly explored in the literature. This work reviews the principal methods used to characterize drill cuttings and data about these residues' properties. Some authors have reported the large content of Zn in drill cuttings. These cuttings can be associated with base fluids (as olefins, varying from C11 to C18), and some time crude oil (high range of TPH, unresolved complex mixtures, and PAH compounds). Acute and chronic toxicity tests have shown negative impacts of different types of fluids, the components of these fluids, and cuttings on other marine organisms.


Sujet(s)
Alcènes , Pétrole , Tests de toxicité chronique
3.
J Med Virol ; 95(6): e28859, 2023 06.
Article de Anglais | MEDLINE | ID: mdl-37314232

RÉSUMÉ

Since 1999, Vaccinia virus (VACV) has been described as a causative agent of bovine vaccinia (BV), a zoonotic disease that occurs mainly in rural areas of Brazil. However, the circulation of VACV in urban environments and its associated burden has been poorly explored. Moreover, the current monkeypox (mpox) outbreak has raised questions regarding the immune status of the worldwide population previous vaccinated against smallpox. Hence, we conducted a cross-sectional study to better understand the prevalence of anti-OPV neutralizing antibodies (NA) and related exposure factors in a susceptible urban population of Brazil. A total of 372 individuals were sampled, yielding an overall seroprevalence of 16.9% (CI95% = 13.4-21.1), and antibodies titers ranging from 100 to 800 neutralizing units/mL. The prevalence of NA among individuals potentially vaccinated against smallpox (≥36 years old [yo]) was 24.9% (IC 95% = 19.5-31.2), and among those unvaccinated (<36yo) was 6.7% (IC 95% = 3.7-11.8). Interestingly, contact with horses was pointed out as an exposure factor for the presence of NA, however, the multivariate logistic regression analysis indicated that age ≥36yo and the presence of vaccine take were independently associated with the presence of anti-OPV NA. Our findings suggest that vulnerable populations could be subclinically exposed to VACV in urban areas, drawing attention to alternative routes of zoonotic VACV exposure. Our data is also important for better strategies to mitigate zoonotic OPV infections mainly among vulnerable populations.


Sujet(s)
Maladies transmissibles , Orthopoxvirus , Variole , Equus caballus , Humains , Animaux , Bovins , Population urbaine , Brésil/épidémiologie , Prévalence , Études transversales , Études séroépidémiologiques , Virus de la vaccine , Zoonoses/épidémiologie , Anticorps neutralisants
4.
Emerg Infect Dis ; 29(3): 664-667, 2023 03.
Article de Anglais | MEDLINE | ID: mdl-36823719

RÉSUMÉ

We tested coatis (Nasua nasua) living in an urban park near a densely populated area of Brazil and found natural SARS-CoV-2 Zeta variant infections by using quantitative reverse transcription PCR, genomic sequencing, and serologic surveillance. We recommend a One Health strategy to improve surveillance of and response to COVID-19.


Sujet(s)
COVID-19 , Procyonidae , Animaux , Humains , SARS-CoV-2 , Brésil/épidémiologie
5.
Med Sci Educ ; 31(6): 2093-2104, 2021 Dec.
Article de Anglais | MEDLINE | ID: mdl-34956714

RÉSUMÉ

This study aims to investigate the effectiveness of the use of different feedback modalities in improving the knowledge, attitudes, and skills of medical students compared to students receiving no feedback or unstructured feedback. A systematic review and meta-analysis of randomized controlled trials was conducted based on a search of the Cochrane, ERIC, PubMed, Scopus, and Web of Science databases. A total of 26 studies were included for the systematic review and 13 for the meta-analysis. The meta-analysis revealed that the use of feedback was associated with better results compared to control groups (SMD = 0.80 [0.56-1.04], p < 0.001), and also when only high-quality studies were included (SMD = 0.86 [0.56-1.16], p < 0.001). Our findings revealed high heterogeneity in the use of feedback in medical education. However, the results of most of the studies and of the meta-analysis were positive, showing that feedback had a positive influence on the education-learning process of the students. PROSPERO registration: CRD42018112688.

6.
Rev Enferm UFPI ; 10(1): e825, 2021-09-15. ilus, tab
Article de Anglais, Portugais | LILACS, BDENF - Infirmière | ID: biblio-1517964

RÉSUMÉ

Objetivo:comparar a efetividade de dois programas de educação permanente para aquisição de habilidades psicomotoras relacionadas à ressuscitação cardiopulmonar em lactentes, a partir da utilização do método tradicional de ensino de suporte básico de vida, comparado ao método com utilização de vídeo com treino autodidata em manequim. Métodos: ensaio controlado com membros da equipe de enfermagem, randomizados em grupo controle (treino tradicional) e intervenção (treino autodidata). Para averiguar as habilidades no atendimento de ressuscitação cardiopulmonar em lactentes, aplicou-se um checklist. Foi aplicado pré-teste, seguido de treinamento imediato, follow-upde 15 dias, com reaplicação da avaliação de habilidades (pós-teste). Resultados:participaram 41 técnicos de enfermagem e 11 enfermeiros. No pós-teste, houve diferença significativa do grupo intervenção (12,61 +2,09) em relação ao grupo controle (14,65 +2,01) (p=0,001). Em ambos osgruposhouve aumento nas pontuações após 15 dias. Conclusão: os profissionais que participaram do treino tradicional (grupo controle) e que receberam feedbacksobre seu desempenho obtiveram melhores resultados para habilidades relacionadas à ressuscitação cardiopulmonar em lactentes.


Objective:To compare the effectiveness of two programs of permanent education for the acquisition of psychomotor skills related to infant cardiopulmonary resuscitation, comparing the traditional basic life support teaching method with the use of a video for self-education with a manikin. Methods:Controlled trial with members from the nursing team, randomized in a control group (traditional training) and an intervention group (self-taught). A checklist was used to evaluate infant cardiopulmonary resuscitation skills. A pre-test was applied, immediately followed by training and a 15-day follow up, when the skills were reevaluated (post-test). Results:41 nursing technicians and 11 nurses participated. In the post test, there was a significant difference between the intervention (12.61 +2.09) and control groups (14.65 +2.01) (p=0.001). The score of both groups improved after 15 days. Conclusion:Professionals who participated in the traditional training (control group) and received feedback about their performance had better results in regard to their skills in infant cardiopulmonary resuscitation


Sujet(s)
Soins infirmiers pédiatriques , Réanimation cardiopulmonaire , Nourrisson , Équipe infirmiers
8.
Preprint de Anglais | medRxiv | ID: ppmedrxiv-20094631

RÉSUMÉ

ImportanceThe COVID-19 pandemic has resulted in more than 3.5 million cases and 245 thousand deaths worldwide as of May 6, 2020. Determining the extent of the presence of the virus on public surfaces is critical for understanding the potential risk of infection in these areas. ObjectiveTo evaluate the presence of SARS-CoV-2 RNA on public surfaces in a densely populated urban area in Brazil. Design and SettingA total of 101 samples were collected from different surfaces in public places in the region of Belo Horizonte with the highest number of COVID-19 cases. Samples were collected near the hospital and public transportation areas using sterile swabs, and then submitted to nucleic acid extraction and genomic detection and quantification by one-step qPCR. ResultsSeventeen of the 101 samples tested positive (16.8%) for SARS-CoV-2 RNA, including samples from bus stations/terminals, public squares, and sidewalks, including those near hospitals. Conclusions and RelevanceOur data indicated the contamination of public surfaces by SARS-CoV-2, especially near hospital areas, highlighting the risk of infection for the population. Constant monitoring of the virus in urban areas is required as a strategy to fight the pandemic and prevent further infections. Key points Question Can SARS-CoV-2 be detected on surfaces in public areas used by a large proportion of the population? FindingsSARS-CoV-2 RNA was detected in different locations, including bus stations/terminals, squares, and sidewalks, especially those near hospitals, in a densely populated area of Belo Horizonte, Brazil. MeaningThis study highlights the need for constant monitoring for the presence of SARS-CoV-2 RNA in urban areas to support better strategies to fight the COVID-19 pandemic and prevent further infections.

9.
Sci Adv ; 6(14): eaaz0421, 2020 04.
Article de Anglais | MEDLINE | ID: mdl-32284978

RÉSUMÉ

Blue natural pigments are rare, especially among plants. However, flowering species that evolved to attract Hymenoptera pollinators are colored by blue anthocyanin-metal complexes. Plants lacking anthocyanins are pigmented by betalains but are unable to produce blue hues. By extending the π-system of betalains, we designed a photostable and metal-free blue dye named BeetBlue that did not show toxicity to human hepatic and retinal pigment epithelial cells and does not affect zebrafish embryonal development. This chiral dye can be conveniently synthesized from betalamic acid obtained from hydrolyzed red beetroot juice or by enzymatic oxidation of l-dopa. BeetBlue is blue in the solid form and in solution of acidified polar molecular solvents, including water. Its capacity to dye natural matrices makes BeetBlue the prototype of a new class of low-cost bioinspired chromophores suitable for a myriad of applications requiring a blue hue.


Sujet(s)
Agents colorants/composition chimique , Agents colorants/isolement et purification , Pigments biologiques/composition chimique , Plantes/composition chimique , Animaux , Phénomènes chimiques , Couleur , Agents colorants/analyse , Agents colorants/toxicité , Théorie de la fonctionnelle de la densité , Métaux , Structure moléculaire , Pigmentation , Analyse spectrale , Danio zébré
10.
Blood Press Monit ; 25(3): 147-154, 2020 Jun.
Article de Anglais | MEDLINE | ID: mdl-31913150

RÉSUMÉ

BACKGROUND: The objective of this study was to assess the effect of feedback on medium-term blood pressure (BP) measurement skills in medical students versus a control group. METHODS: A randomized controlled trial in first-year medical students was conducted. After theoretical-practical training on measuring BP, the students were randomized into a control group or intervention group. The skill was assessed immediately after the training (T1) by evaluating students with a simulated standardized patient using a checklist. Students in the intervention group received feedback immediately after assessment, whereas the control group received no feedback. After 3 months (T2), each student was reassessed in the same way as for (T1). RESULTS: Ninety-two first-year medical students took part in the study (45 in control group and 47 in intervention group). At T1, there were no differences in the skill measured. At T2 (after three months), there was a significant difference in the intervention group (score = 23.97 ± 3.82) compared with the control group (score = 20.91 ± 4.87), P < 0.001, d = 0.69. In the intervention group, the scores were maintained at 3 months (T1 = 23.23 and T2 = 23.97, P = 0.335), whereas in the control group, scores declined significantly (T1 = 23.44 and T2 = 20.91; P = 0.002). CONCLUSION: Receiving feedback promotes retention of learning of BP measurement skills over the medium term. Further studies applying feedback to other skills should be conducted.


Sujet(s)
Enseignement médical premier cycle , Étudiant médecine , Pression sanguine , Compétence clinique , Rétroaction , Humains
11.
Sci Adv, v. 6, n. 14, eaaz0421, abr. 2020
Article de Anglais | Sec. Est. Saúde SP, SESSP-IBPROD, Sec. Est. Saúde SP | ID: bud-3010

RÉSUMÉ

Blue natural pigments are rare, especially among plants. However, flowering species that evolved to attract Hymenoptera pollinators are colored by blue anthocyanin-metal complexes. Plants lacking anthocyanins are pigmented by betalains but are unable to produce blue hues. By extending the p-system of betalains, we designed a photostable and metal-free blue dye named BeetBlue that did not show toxicity to human hepatic and retinal pigment epithelial cells and does not affect zebrafish embryonal development. This chiral dye can be conveniently synthesized from betalamic acid obtained from hydrolyzed red beetroot juice or by enzymatic oxidation of L-dopa. BeetBlue is blue in the solid form and in solution of acidified polar molecular solvents, including water. Its capacity to dye natural matrices makes BeetBlue the prototype of a new class of low-cost bioinspired chromophores suitable for a myriad of applications requiring a blue hue.

12.
Sci. Adv. ; 6(14): eaaz0421, 2020.
Article de Anglais | Sec. Est. Saúde SP, SESSP-IBPROD, Sec. Est. Saúde SP | ID: but-ib17609

RÉSUMÉ

Blue natural pigments are rare, especially among plants. However, flowering species that evolved to attract Hymenoptera pollinators are colored by blue anthocyanin-metal complexes. Plants lacking anthocyanins are pigmented by betalains but are unable to produce blue hues. By extending the p-system of betalains, we designed a photostable and metal-free blue dye named BeetBlue that did not show toxicity to human hepatic and retinal pigment epithelial cells and does not affect zebrafish embryonal development. This chiral dye can be conveniently synthesized from betalamic acid obtained from hydrolyzed red beetroot juice or by enzymatic oxidation of L-dopa. BeetBlue is blue in the solid form and in solution of acidified polar molecular solvents, including water. Its capacity to dye natural matrices makes BeetBlue the prototype of a new class of low-cost bioinspired chromophores suitable for a myriad of applications requiring a blue hue.

13.
Genet Mol Res ; 16(3)2017 Sep 21.
Article de Anglais | MEDLINE | ID: mdl-28973741

RÉSUMÉ

The objective of this study was to estimate the adaptability and stability of grain sorghum hybrids grown under post-flowering water stress and non-stress conditions. The trials were carried out in Nova Porteirinha-MG during the season of 2014 and 2015, and in Teresina-PI in the 2014 season. Twenty-nine-grain sorghum hybrids were evaluated, in a randomized complete block design, with three replications. Plots consisted of four lines with 3 m long. The grain yield data were submitted to the individual variance analysis, having considered the effects of the hybrids as fixed and the other effects as random. The joint analysis was carried out, and when the interaction genotypes x environments was significant, the grain yield data were submitted to the adaptability and stability analysis by the GGE biplot method. A substantial reduction in the grain yield in environments with water stress was found. The highest yielding hybrids under water stress conditions in Nova Porteirinha-MG were 50A50, AG1080, AG1090, DKB550, DKB590, Jade, and BM737, and the highest yielding hybrids under the water stress in Teresina-PI were 1G282, 1G244, and A9721R. Considering all environments, the highest yielding hybrids were 1G282, DKB540, A9721R, 1G100, and AG1090.


Sujet(s)
Hybridation génétique , Amélioration des plantes , Sorghum/génétique , Stress physiologique , Sécheresses , Interaction entre gènes et environnement , Génotype
14.
Nursing (Ed. bras., Impr.) ; 20(225): 1576-1579, fev.2017.
Article de Portugais | LILACS, BDENF - Infirmière | ID: biblio-869188

RÉSUMÉ

Objetivos: analisar os elementos do cuidado de enfermagem em Oncologia ao paciente portador de doença que ameaça a vida na perspectiva do enfermeiro; discutir a interface existente entre o cuidado significado pelo enfermeiro e a Teoria do Cuidado Transpessoal. Método: Estudo qualitativo, com análise de conteúdo em Bardin. Teve como cenário uma instituição hospitalar de Minas Gerais e participaram 12 enfermeiros entrevistados entre setembro/outubro/2014. Resultados: Emergiram duas categorias: Significados do cuidado de enfermagem ao paciente fora de possibilidade de tratamento modificador da doença; Cuidando com o que se tem de melhor: Técnica, sentimentos e interação multiprofissional. Conclusão: Os elementos do cuidado de enfermagem apontados podem ser subsidiados pela Teoria do Cuidado Transpessoal e vão ao encontro das perspectivas apontadas como necessárias pela Política Nacional de Atenção Oncológica e pelo Manual de Cuidados Paliativos.


Sujet(s)
Humains , Soins palliatifs , Soins infirmiers , Soins infirmiers en oncologie , Théorie des soins infirmiers
15.
Genet Mol Res ; 15(2)2016 May 13.
Article de Anglais | MEDLINE | ID: mdl-27323025

RÉSUMÉ

The purpose of this study was to identify parents and obtain segregating populations of cowpea (Vigna unguiculata L. Walp.) with the potential for tolerance to water deficit. A full diallel was performed with six cowpea genotypes, and two experiments were conducted in Teresina, PI, Brazil in 2011 to evaluate 30 F2 populations and their parents, one under water deficit and the other under full irrigation. A triple-lattice experimental design was used, with six 2-m-long rows in each plot. Sixteen plants were sampled per plot. The data were subjected to analysis of variance, and general and specific combining ability estimates were obtained based on the means. Additive effects were more important than non-additive effects, and maternal inheritance had occurred. The genotypes BRS Xiquexique, Pingo de Ouro-1-2, and MNC99-510F-16-1 were the most promising for use in selection programs aimed at water deficit tolerance. The hybrid combinations Pingo de Ouro-1-2 x BRS Xiquexique, BRS Xiquexique x Santo Inácio, CNCx 698-128G x MNC99-510F-16-1, Santo Inácio x CNCx 698-128G, MNC99-510F-16-1 x BRS Paraguaçu, MNC99- 510F-16-1 x Pingo de Ouro-1-2, and MNC99-510F-16-1 x BRS Xiquexique have the potential to increase grain production and tolerate water deficit.


Sujet(s)
Vigna/génétique , Brésil , Sécheresses , Fréquence d'allèle , Génétique des populations/méthodes , Génotype
16.
PLoS One ; 11(5): e0154325, 2016.
Article de Anglais | MEDLINE | ID: mdl-27152840

RÉSUMÉ

UNLABELLED: Breast cancer (BC) in young adult patients (YA) has a more aggressive biological behavior and is associated with a worse prognosis than BC arising in middle aged patients (MA). We proposed that differentially expressed miRNAs could regulate genes and proteins underlying aggressive phenotypes of breast tumors in YA patients when compared to those arising in MA patients. OBJECTIVE: Using integrated expression analyses of miRs, their mRNA and protein targets and stromal gene expression, we aimed to identify differentially expressed profiles between tumors from YA-BC and MA-BC. METHODOLOGY AND RESULTS: Samples of ER+ invasive ductal breast carcinomas, divided into two groups: YA-BC (35 years or less) or MA-BC (50-65 years) were evaluated. Screening for BRCA1/2 status according to the BOADICEA program indicated low risk of patients being carriers of these mutations. Aggressive characteristics were more evident in YA-BC versus MA-BC. Performing qPCR, we identified eight miRs differentially expressed (miR-9, 18b, 33b, 106a, 106b, 210, 518a-3p and miR-372) between YA-BC and MA-BC tumors with high confidence statement, which were associated with aggressive clinicopathological characteristics. The expression profiles by microarray identified 602 predicted target genes associated to proliferation, cell cycle and development biological functions. Performing RPPA, 24 target proteins differed between both groups and 21 were interconnected within a network protein-protein interactions associated with proliferation, development and metabolism pathways over represented in YA-BC. Combination of eight mRNA targets or the combination of eight target proteins defined indicators able to classify individual samples into YA-BC or MA-BC groups. Fibroblast-enriched stroma expression profile analysis resulted in 308 stromal genes differentially expressed between YA-BC and MA-BC. CONCLUSION: We defined a set of differentially expressed miRNAs, their mRNAs and protein targets and stromal genes that distinguish early onset from late onset ER positive breast cancers which may be involved with tumor aggressiveness of YA-BC.


Sujet(s)
Tumeurs du sein/anatomopathologie , microARN/génétique , Récepteurs des oestrogènes/métabolisme , Sujet âgé , Tumeurs du sein/génétique , Tumeurs du sein/métabolisme , Femelle , Analyse de profil d'expression de gènes , Humains , Adulte d'âge moyen
17.
Braz J Biol ; 75(4): 821-9, 2015 Nov.
Article de Anglais | MEDLINE | ID: mdl-26628236

RÉSUMÉ

Eucalyptus plantations are frequently used for the establishment of bee yards. This study was carried on at Fazenda Brejão, northwestern region of the State of Minas Gerais, Brazil. This farm is covered both with native Cerrado vegetation (Brazilian savanna) and eucalyptus plantations. This paper reports on the botanic origin of pollen pellets and honey collected from honeybee (Apis mellifera) hives along a thirteen-month period (January 2004 to January 2005). The most frequent pollen types found in the pollen pellets during the rainy season were Trema micrantha (Ulmaceae), Copaifera langsdorffii (Fabaceae), an unidentified Poaceae, unidentified Asteraceae-2, Cecropia sp. 1 (Cecropiaceae) and Eucalyptus spp. (Myrtaceae); during the dry season the most frequent pollen types were Acosmium dasycarpum (Fabaceae), Cecropia sp. 1 (Cecropiaceae) and Eucalyptus spp. (Myrtaceae). Pollen grains of Baccharis sp. (Asteraceae), Cecropia sp. 1 (Cecropiaceae), Copaifera langsdorffii (Fabaceae), Mimosa nuda (Fabaceae), Eucalyptus spp. (Myrtaceae) and Trema micrantha (Ulmaceae) were present in the honey samples throughout the study period.


Sujet(s)
Abeilles/physiologie , Environnement , Miel/analyse , Pollen/composition chimique , Animaux , Brésil , Eucalyptus/croissance et développement , Science forêt , Prairie , Saisons
18.
Genet Mol Res ; 14(4): 15981-7, 2015 Dec 07.
Article de Anglais | MEDLINE | ID: mdl-26662390

RÉSUMÉ

Vigna unguiculata (L.) Walp (cowpea) is a food crop with high nutritional value that is cultivated throughout tropical and subtropical regions of the world. The main constraint on high productivity of cowpea is water deficit, caused by the long periods of drought that occur in these regions. The aim of the present study was to select elite cowpea genotypes with enhanced drought tolerance, by applying principal component analysis to 219 first-cycle progenies obtained in a recurrent selection program. The experimental design comprised a simple 15 x 15 lattice with 450 plots, each of two rows of 10 plants. Plants were grown under water-deficit conditions by applying a water depth of 205 mm representing one-half of that required by cowpea. Variables assessed were flowering, maturation, pod length, number and mass of beans/pod, mass of 100 beans, and productivity/plot. Ten elite cowpea genotypes were selected, in which principal components 1 and 2 encompassed variables related to yield (pod length, beans/pod, and productivity/plot) and life precocity (flowering and maturation), respectively.


Sujet(s)
Adaptation biologique , Sécheresses , Fabaceae/génétique , Fabaceae/métabolisme , Études d'associations génétiques , Caractère quantitatif héréditaire , Sélection génétique , Génotype , Phénotype , Analyse en composantes principales
19.
J Genet ; 94(4): 651-9, 2015 Dec.
Article de Anglais | MEDLINE | ID: mdl-26690520

RÉSUMÉ

Elevated levels of interleukin-1 (IL-1) have been shown to amplify the inflammatory response against periodontopathogenic bacteria.In humans,polymorphisms in the IL1A and IL1B genes are the most well-studied genetic polymorphisms associated with periodontal disease (PD). In contrast to human, there is a lack of knowledge on the genetic basis of canine PD. A case-control study was conducted in which a molecular analysis of dog IL1A and IL1B genes was performed. Of the eight genetic variants identified, seven in IL1A gene and one in IL1B gene, IL1A/1_g.388A>C and IL1A /1_g.521T>A showed statistically significant differences between groups (adjusted OR (95% CI): 0.15 (0.03-0.76),P=0.022; 5.76 (1.03-32.1),P=0.046, respectively). It suggests that in the studied population the IL1A/1_g.388C allele is associated with a decreased PD risk, whereas the IL1A/1_g.521A allele can confer an increased risk. Additionally, the IL1A/2_g.515G>T variation resulted in a change of amino acid, i.e. glycine to valine. In silico analysis suggests that this change can alter protein structure and function, predicting it to be deleterious or damaging. This work suggests that IL1 genetic variants may be important in PD susceptibility in canines.


Sujet(s)
Prédisposition génétique à une maladie/génétique , Variation génétique/génétique , Interleukine-1 alpha/génétique , Interleukine-1 bêta/génétique , Maladies parodontales/génétique , Allèles , Animaux , Études cas-témoins , Chiens , Génotype , Risque
20.
Braz. j. biol ; 75(4): 821-829, Nov. 2015. tab
Article de Anglais | LILACS | ID: lil-768213

RÉSUMÉ

Abstract Eucalyptus plantations are frequently used for the establishment of bee yards. This study was carried on at Fazenda Brejão, northwestern region of the State of Minas Gerais, Brazil. This farm is covered both with native Cerrado vegetation (Brazilian savanna) and eucalyptus plantations. This paper reports on the botanic origin of pollen pellets and honey collected from honeybee (Apis mellifera) hives along a thirteen-month period (January 2004 to January 2005). The most frequent pollen types found in the pollen pellets during the rainy season were Trema micrantha (Ulmaceae), Copaifera langsdorffii (Fabaceae), an unidentified Poaceae, unidentified Asteraceae-2, Cecropia sp. 1 (Cecropiaceae) and Eucalyptus spp. (Myrtaceae); during the dry season the most frequent pollen types were Acosmium dasycarpum (Fabaceae), Cecropia sp. 1 (Cecropiaceae) and Eucalyptus spp. (Myrtaceae). Pollen grains of Baccharis sp. (Asteraceae), Cecropia sp. 1 (Cecropiaceae), Copaifera langsdorffii (Fabaceae), Mimosa nuda (Fabaceae), Eucalyptus spp. (Myrtaceae) and Trema micrantha (Ulmaceae) were present in the honey samples throughout the study period.


Resumo Plantações de Eucalyptus são, frequentemente, utilizadas como locais de instalação para colmeias. Este estudo foi realizado na Fazenda Brejão, localizada no noroeste de Minas Gerais, Brasil. Esta fazenda é coberta por Cerrado nativo (savana brasileira) e por plantações de eucaliptos. Este trabalho indica a origem botânica de bolotas e mel coletados em colmeias de Apis mellifera por um período de 13 meses (Janeiro/2004 a janeiro/2005). Os tipos polínicos mais frequentes nas amostras de pólen durante a estação chuvosa foram Trema micrantha (Ulmaceae), Copaifera langsdorffii (Fabaceae), Poaceae, Asteraceae não identificada 2, Cecropia sp. 1 (Cecropiaceae) e Eucalyptus spp. (Myrtaceae); na estação seca, os tipos polínicos mais frequentes foram Acosmium dasycarpum (Fabaceae), Cecropia sp. 1 (Cecropiaceae) e Eucalyptus spp. (Myrtaceae). As espécies Baccharis sp. (Asteraceae), Cecropia sp. 1 (Cecropiaceae), Copaifera langsdorffii (Fabaceae), Mimosa nuda (Fabaceae), Eucalyptus spp. (Myrtaceae) e Trema micrantha (Ulmaceae) estiveram presentes durante todo o período amostrado.


Sujet(s)
Animaux , Abeilles/physiologie , Environnement , Miel/analyse , Pollen/composition chimique , Brésil , Eucalyptus/croissance et développement , Science forêt , Prairie , Saisons
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