2024: anticipating record-breaking performances in front crawl swimming through mathematical analysis.

Introduction: This study presented a novel approach to predict future front crawl swimming world records (WRs) by employing a methodology that integrated performance data from both running and front crawl swimming. Methods: By extracting the top one running and swimming performances from 1995 to 2023 and applying a model that correlates physiological characteristics such as maximum aerobic power, anaerobic capacity, the decrement in maximum power with prolonged effort, and performance speed and duration, it was possible to project the potential record-breaking performances in 2024 across various swimming distances for both male and female athletes. Furthermore, this approach was expected to be less susceptible to the influence of the full-body swimsuit era, which may have disrupted the typical trajectory of swimming performance progression. Results: The average relative error between the top one and estimated speeds in front crawl swimming (50-1,500 m, from 1995 to 2023, and for male and female) was 0.56% ± 0.17%. For male, WR in longer distances have been predicted with new WR in the 400 and 800 m. A more ambitious prediction was noted among female, with twice as many WR as among male illustrated by new WR in the 50, 200, 400 and 800 m. Discussion: This study illustrated that the utilization of a prediction model based on physiological parameters yielded plausible time estimates. Additionally, the research accentuated the ongoing trajectory of surpassing existing WR into 2024, illustrating the competitive zeal fueled by an emerging framework of exceptional swimmers.

DNA methylation changes during a sprint interval exercise performed under normobaric hypoxia or with blood flow restriction: A pilot study in men.

This crossover study evaluated DNA methylation changes in human salivary samples following single sprint interval training sessions performed in hypoxia, with blood flow restriction (BFR), or with gravity-induced BFR. Global DNA methylation levels were evaluated with an enzyme-linked immunosorbent assay. Methylation-sensitive restriction enzymes were used to determine the percentage methylation in a part of the promoter of the gene-inducible nitric oxide synthase (p-iNOS), as well as an enhancer (e-iNOS). Global methylation increased after exercise (p < 0.001; dz = 0.50). A tendency was observed for exercise × condition interaction (p = 0.070). Post hoc analyses revealed a significant increase in global methylation between pre- (7.2 ± 2.6%) and postexercise (10.7 ± 2.1%) with BFR (p = 0.025; dz = 0.69). Methylation of p-iNOS was unchanged (p > 0.05). Conversely, the methylation of e-iNOS increased from 0.6 ± 0.4% to 0.9 ± 0.8% after exercise (p = 0.025; dz = 0.41), independently of the condition (p > 0.05). Global methylation correlated with muscle oxygenation during exercise (r = 0.37, p = 0.042), while e-iNOS methylation showed an opposite association (r = -0.60, p = 0.025). Furthermore, p-iNOS methylation was linked to heart rate (r = 0.49, p = 0.028). Hence, a single sprint interval training increases global methylation in saliva, and adding BFR tends to increase it further. Lower muscle oxygenation is associated with augmented e-iNOS methylation. Finally, increased cardiovascular strain results in increased p-iNOS methylation.

Impact of systemic hypoxia and blood flow restriction on mechanical, cardiorespiratory, and neuromuscular responses to a multiple-set repeated sprint exercise.

Introduction: Repeated sprint cycling exercises (RSE) performed under systemic normobaric hypoxia (HYP) or with blood flow restriction (BFR) are of growing interest. To the best of our knowledge, there is no stringent consensus on the cardiorespiratory and neuromuscular responses between systemic HYP and BFR during RSE. Thus, this study assessed cardiorespiratory and neuromuscular responses to multiple sets of RSE under HYP or with BFR. Methods: According to a crossover design, fifteen men completed RSE (three sets of five 10-s sprints with 20 s of recovery) in normoxia (NOR), HYP, and with bilaterally-cuffed BFR at 45% of resting arterial occlusive pressure during sets in NOR. Power output, cardiorespiratory and neuromuscular responses were assessed. Results: Average peak and mean powers were lower in BFR (dz = 0.87 and dz = 1.23, respectively) and HYP (dz = 0.65 and dz = 1.21, respectively) compared to NOR (p < 0.001). The percentage decrement of power output was greater in BFR (dz = 0.94) and HYP (dz = 0.64) compared to NOR (p < 0.001), as well as in BFR compared to NOR (p = 0.037, dz = 0.30). The percentage decrease of maximal voluntary contraction of the knee extensors after the session was greater in BFR compared to NOR and HYP (p = 0.011, dz = 0.78 and p = 0.027, dz = 0.75, respectively). Accumulated ventilation during exercise was higher in HYP and lower in BFR (p = 0.002, dz = 0.51, and p < 0.001, dz = 0.71, respectively). Peak oxygen consumption was reduced in HYP (p < 0.001, dz = 1.47). Heart rate was lower in BFR during exercise and recovery (p < 0.001, dz = 0.82 and p = 0.012, dz = 0.43, respectively). Finally, aerobic contribution was reduced in HYP compared to NOR (p = 0.002, dz = 0.46) and BFR (p = 0.005, dz = 0.33). Discussion: Thus, this study indicates that power output during RSE is impaired in HYP and BFR and that BFR amplifies neuromuscular fatigue. In contrast, HYP did not impair neuromuscular function but enhanced the ventilatory response along with reduced oxygen consumption.

Active recovery vs hot- or cold-water immersion for repeated sprint ability after a strenuous exercise training session in elite skaters.

This study compared the acute effects of three recovery methods: active recovery (AR), hot- and cold-water immersion (HWI and CWI, respectively), used between two training sessions in elite athletes. Twelve national-team skaters (7 males, 5 females) completed three trials according to a randomized cross-over study. Fifteen minutes after an exhaustive ice-skating training session, participants underwent 20 min of HWI (41.1 ± 0.5°C), 15 min of CWI (12.1 ± 0.7°C) or 15 min of active recovery (AR). After 1 h 30 min of the first exercise, they performed a repeated-sprint cycling session. Average power output was slightly but significantly higher for AR (767 ± 179 W) and HWI (766 ± 170 W) compared to CWI (738 ± 156 W) (p = 0.026, d = 0.18). No statistical difference was observed between the conditions for both lactatemia and rating of perceived exertion. Furthermore, no significant effect of recovery was observed on the fatigue index calculated from the repeated sprint cycling exercises (p > 0.05). Finally, a positive correlation was found between the average muscle temperature measured during the recoveries and the maximal power output obtained during cycling exercises. In conclusion, the use of CWI in between high-intensity training sessions could slightly impair the performance outcomes compared to AR and HWI. However, studies with larger samples are needed to confirm these results, especially in less trained athletes.

Biomechanical adaptations during exhaustive runs at 90 to 120% of peak aerobic speed.

The aim of this study was to examine how running biomechanics (spatiotemporal and kinetic variables) adapt with exhaustion during treadmill runs at 90, 100, 110, and 120% of the peak aerobic speed (PS) of a maximal incremental aerobic test. Thirteen male runners performed a maximal incremental aerobic test on an instrumented treadmill to determine their PS. Biomechanical variables were evaluated at the start, mid, and end of each run until volitional exhaustion. The change of running biomechanics with fatigue was similar among the four tested speeds. Duty factor and contact and propulsion times increased with exhaustion (P ≤ 0.004; F ≥ 10.32) while flight time decreased (P = 0.02; F = 6.67) and stride frequency stayed unchanged (P = 0.97; F = 0.00). A decrease in vertical and propulsive peak forces were obtained with exhaustion (P ≤ 0.002; F ≥ 11.52). There was no change in the impact peak with exhaustion (P = 0.41; F = 1.05). For runners showing impact peaks, the number of impact peaks increased (P ≤ 0.04; [Formula: see text] ≥ 6.40) together with the vertical loading rate (P = 0.005; F = 9.61). No changes in total, external, and internal positive mechanical work was reported with exhaustion (P ≥ 0.12; F ≤ 2.32). Results suggest a tendency towards a "smoother" vertical and horizontal running pattern with exhaustion. A smoother running pattern refers to the development of protective adjustments, leading to a reduction of the load applied to the musculoskeletal system at each running step. This transition seemed continuous between the start and end of the running trials and could be adopted by the runners to decrease the muscle force level during the propulsion phase. Despite these changes with exhaustion, there were no changes in either gesture speed (no alteration of stride frequency) or positive mechanical work, advocating that runners unconsciously organize themselves to maintain a constant whole-body mechanical work output.

Effects of short-term repeated sprint training in hypoxia or with blood flow restriction on response to exercise.

This study compared the effects of a brief repeated sprint training (RST) intervention performed with bilateral blood flow restriction (BFR) conditions in normoxia or conducted at high levels of hypoxia on response to exercise. Thirty-nine endurance-trained athletes completed six repeated sprints cycling sessions spread over 2 weeks consisting of four sets of five sprints (10-s maximal sprints with 20-s active recovery). Athletes were assigned to one of the four groups and subjected to a bilateral partial blood flow restriction (45% of arterial occlusion pressure) of the lower limbs during exercise (BFRG), during the recovery (BFRrG), exercised in a hypoxic room simulating hypoxia at FiO2 ≈ 13% (HG) or were not subjected to additional stress (CG). Peak aerobic power during an incremental test, exercise duration, maximal accumulated oxygen deficit and accumulated oxygen uptake (VO2) during a supramaximal constant-intensity test were improved thanks to RST (p < 0.05). No significant differences were observed between the groups (p > 0.05). No further effect was found on other variables including time-trial performance and parameters of the force-velocity relationship (p > 0.05). Thus, peak aerobic power, exercise duration, maximal accumulated oxygen deficit, and VO2 were improved during a supramaximal constant-intensity exercise after six RST sessions. However, combined hypoxic stress or partial BFR did not further increase peak aerobic power.

Muscle Deoxygenation Rates and Reoxygenation Modeling During a Sprint Interval Training Exercise Performed Under Different Hypoxic Conditions.

This study compared the kinetics of muscle deoxygenation and reoxygenation during a sprint interval protocol performed under four modalities: blood flow restriction at 60% of the resting femoral artery occlusive pressure (BFR), gravity-induced BFR (G-BFR), simulated hypoxia (FiO2≈13%, HYP) and normoxia (NOR). Thirteen healthy men performed each session composed of five all-out 30-s efforts interspaced with 4 min of passive recovery. Total work during the exercises was 17 ± 3.4, 15.8 ± 2.9, 16.7 ± 3.4, and 18.0 ± 3.0 kJ for BFR, G-BFR, HYP and NOR, respectively. Muscle oxygenation was continuously measured with near-infrared spectroscopy. Tissue saturation index (TSI) was modelled with a linear function at the beginning of the sprint and reoxygenation during recovery with an exponential function. Results showed that both models were adjusted to the TSI (R2 = 0.98 and 0.95, respectively). Greater deoxygenation rates were observed in NOR compared to BFR (p = 0.028). No difference was found between the conditions for the deoxygenation rates relative to sprint total work (p > 0.05). Concerning reoxygenation, the amplitude of the exponential was not different among conditions (p > 0.05). The time delay of reoxygenation was longer in BFR compared to the other conditions (p < 0.05). A longer time constant was found for G-BFR compared to the other conditions (p < 0.05), and mean response time was longer for BFR and G-BFR. Finally, sprint performance was correlated with faster reoxygenation. Hence, deoxygenation rates were not different between the conditions when expressed relatively to total sprint work. Furthermore, BFR conditions impair reoxygenation: BFR delays and G-BFR slows down reoxygenation.

Effects of Active Preconditioning With Local and Systemic Hypoxia on Submaximal Cycling.

PURPOSE: The authors compared the effects of active preconditioning with local and systemic hypoxia during submaximal cycling. METHODS: On separate visits, 14 active participants completed 4 trials. Each visit was composed of 1 preconditioning phase followed, after 40 minutes of rest, by 3 × 6-minute cycling bouts (intensity = 85% of critical power; rest = 6 min). The preconditioning phase consisted of 4 × 5-minute cycling bouts at 1.5 W·kg-1 (rest = 5 min) in 4 conditions: control (no occlusion and normoxia), blood flow restriction (60% of total occlusion), HYP (systemic hypoxia; inspired fraction of oxygen = 13.6%), and blood flow restriction + HYP (local and systemic hypoxia combined). RESULTS: During the preconditioning phase, there were main effects of both systemic (all P < .014) and local hypoxia (all P ≤ .001) on heart rate, arterial oxygen saturation, leg discomfort, difficulty of breathing, and blood lactate concentration. Cardiorespiratory variables, gross efficiency, energy cost, and energy expenditure during the last minute of 6-minute cycling bouts did not differ between conditions (all P > .105). CONCLUSION: Local and systemic hypoxic stimuli, or a combination of both, during active preconditioning did not improve physiological responses such as cycling efficiency during subsequent submaximal cycling.

Oxygen Uptake at Critical Speed and Power in Running: Perspectives and Practical Applications.

PURPOSE: Intensity domains are recommended when prescribing exercise, and critical power/speed (CP/CS) was designated the "gold standard" when determining maximal metabolic steady state. CS is the running analog of CP for cycle ergometry. However, a CP for running could be useful for controlling intensity when training in any type of condition. Therefore, this study aimed to estimate external, internal, and total CP (CPext, CPint, and CPtot), obtained based on running power calculations, and verified whether they occurred at the same percentage of peak oxygen uptake as the usual CS. Furthermore, this study examined whether selecting strides at the start, half, or end of the exhaustive runs to calculate running power influenced the estimation of the 3 CPs. METHODS: Thirteen male runners performed a maximal incremental aerobic test and 4 exhaustive runs (90%, 100%, 110%, 120% peak speed) on a treadmill. The estimations of CS and CPs were obtained using a 3-parameter mathematical model fitted using weighted least square. RESULTS: CS was estimated at 4.3 m/s while the estimates of CPext, CPint, and CPtot were 5.2, 2.6, and 7.8 W/kg, respectively. The corresponding V˙O2 for CS was 82.5 percentage of peak oxygen uptake and 81.3, 79.7, and 80.6 percentage of peak oxygen uptake for CPext, CPint, and CPtot, respectively. No systematic bias was reported when comparing CS and CPext, as well as the 3 different CPs, whereas systematic biases of 2.8% and 1.8% were obtained for the comparison among CS and CPint and CPtot, respectively. Nonetheless, the V˙O2 for CS and CPs were not statistically different (P = .09). Besides, no effect of the time stride selection for CPs as well as their resulting V˙O2 was obtained (P ≥ .44). CONCLUSIONS: The systematic biases among V˙O2 at CS and CPint and CPtot were not clinically relevant. Therefore, CS and CPs closely represent the same fatigue threshold in running. The knowledge of CP in running might prove to be useful for both athletes and coaches, especially when combined with instantaneous running power. Indeed, this combination might help athletes controlling their targeted training intensity and coaches prescribing a training session in any type of condition.

Effects of Blood Flow Restriction on O2 Muscle Extraction and O2 Pulmonary Uptake Kinetics During Heavy Exercise.

This study aimed to determine the effects of three levels of blood flow restriction (BFR) on V ˙ O 2 and O 2 extraction kinetics during heavy cycling exercise transitions. Twelve healthy trained males completed two bouts of 10 min heavy intensity exercise without BFR (CON), with 40% or 50% BFR (BFR40 and BFR50, respectively). V ˙ O 2 and tissue saturation index (TSI) were continuously measured and modelled using multiexponential functions. The time constant of the V ˙ O 2 primary phase was significantly slowed in BFR40 (26.4 ± 2.0s; p < 0.001) and BFR50 (27.1 ± 2.1s; p = 0.001) compared to CON (19.0 ± 1.1s). The amplitude of the V ˙ O 2 slow component was significantly increased (p < 0.001) with BFR in a pressure-dependent manner 3.6 ± 0.7, 6.7 ± 0.9 and 9.7 ± 1.0 ml·min-1·kg-1 for CON, BFR40, and BFR50, respectively. While no acceleration of the primary component of the TSI kinetics was observed, there was an increase (p < 0.001) of the phase 3 amplitude with BFR (CON -0.8 ± 0.3% VS BFR40 -2.9 ± 0.9%, CON VS BFR50 -2.8 ± 0.8%). It may be speculated that BFR applied during cycling exercise in the heavy intensity domain shifted the working muscles to an O 2 dependent situation. The acceleration of the extraction kinetics could have reached a plateau, hence not permitting compensation for the slowdown of the blood flow kinetics, and slowing V ˙ O 2 kinetics.

Effect of Mathematical Modeling and Fitting Procedures on the Assessment of Critical Speed and Its Relationship With Aerobic Fitness Parameters.

An accurate estimation of critical speed (CS) is important to accurately define the boundary between heavy and severe intensity domains when prescribing exercise. Hence, our aim was to compare CS estimates obtained by statistically appropriate fitting procedures, i.e., regression analyses that correctly consider the dependent variables of the underlying models. A second aim was to determine the correlations between estimated CS and aerobic fitness parameters, i.e., ventilatory threshold, respiratory compensation point, and maximal rate of oxygen uptake. Sixteen male runners performed a maximal incremental aerobic test and four exhaustive runs at 90, 100, 110, and 120% of the peak speed of the incremental test on a treadmill. Then, two mathematically equivalent formulations (time as function of running speed and distance as function of running speed) of three different mathematical models (two-parameter, three-parameter, and three-parameter exponential) were employed to estimate CS, the distance that can be run above CS (d'), and if applicable, the maximal instantaneous running speed (s max ). A significant effect of the mathematical model was observed when estimating CS, d', and s max (P < 0.001), but there was no effect of the fitting procedure (P > 0.77). The three-parameter model had the best fit quality (smallest Akaike information criterion) of the CS estimates but the highest 90% confidence intervals and combined standard error of estimates (%SEE). The 90% CI and %SEE were similar when comparing the two fitting procedures for a given model. High and very high correlations were obtained between CS and aerobic fitness parameters for the three different models (r ≥ 0.77) as well as reasonably small SEE (SEE ≤ 6.8%). However, our results showed no further support for selecting the best mathematical model to estimate critical speed. Nonetheless, we suggest coaches choosing a mathematical model beforehand to define intensity domains and maintaining it over the running seasons.

Modelling performance with exponential functions in elite short-track speed skaters.

Mathematical models are used to describe and predict the effects of training on performance. The initial models are structured by impulse-type transfer functions, however, cellular adaptations induced by exercise may exhibit exponential kinetics for their growth and subsequent dissipation. Accumulation of exercise bouts counteracts dissipation and progressively induces structural and functional changes leading to performance improvement. This study examined the suitability of a model with exponential terms (Exp-Model) in elite short-track speed (ST) skaters. Training loads and performance evolution from fifteen athletes (10 males, 5 females) were previously collected over a 3-month training period. Here, we computed the relationship between training loads and performance with Exp-Model and compared with previous results obtained with a variable dose-response model (Imp-Model). Exp-Model showed a higher correlation between actual and modelled performances (R2 = 0.83 ± 0.08 and 0.76 ± 0.07 for Exp-Model and Imp-Model, respectively). Concerning model parameters, a higher τA1 (time constant for growth) value was found (p = 0.0047; d = 1.4; 95% CI [0.4;1.9]) in males compared to females with Exp-model, suggesting that females have a faster adaptative response to training loads. Thus, according to this study, Exp-model may better describe training adaptations in elite ST athletes than Imp-Model.

Critical speed estimated by statistically appropriate fitting procedures.

PURPOSE: Intensity domains are recommended when prescribing exercise. The distinction between heavy and severe domains is made by the critical speed (CS), therefore requiring a mathematically accurate estimation of CS. The different model variants (distance versus time, running speed versus time, time versus running speed, and distance versus running speed) are mathematically equivalent. Nevertheless, error minimization along the correct axis is important to estimate CS and the distance that can be run above CS (d'). We hypothesized that comparing statistically appropriate fitting procedures, which minimize the error along the axis corresponding to the properly identified dependent variable, should provide similar estimations of CS and d' but that different estimations should be obtained when comparing statistically appropriate and inappropriate fitting procedure. METHODS: Sixteen male runners performed a maximal incremental aerobic test and four exhaustive runs at 90, 100, 110, and 120% of their peak speed on a treadmill. Several fitting procedures (a combination of a two-parameter model variant and regression analysis: weighted least square) were used to estimate CS and d'. RESULTS: Systematic biases (P < 0.001) were observed between each pair of fitting procedures for CS and d', even when comparing two statistically appropriate fitting procedures, though negligible, thus corroborating the hypothesis. CONCLUSION: The differences suggest that a statistically appropriate fitting procedure should be chosen beforehand by the researcher. This is also important for coaches that need to prescribe training sessions to their athletes based on exercise intensity, and their choice should be maintained over the running seasons.

Influence of post-exercise hot-water therapy on adaptations to training over 4 weeks in elite short-track speed skaters.

This study aimed to investigate the effects of regular hot water bathing (HWB), undertaken 10 min after the last training session of the day, on chronic adaptations to training in elite athletes. Six short-track (ST) speed skaters completed four weeks of post-training HWB and four weeks of post-training passive recovery (PR) according to a randomized cross-over study. During HWB, participants sat in a jacuzzi (40 °C; 20 min). According to linear mixed models, maximal isometric strength of knee extensor muscles was significantly increased for training with HWB (p < 0.0001; d = 0.41) and a tendency (p = 0.0529) was observed concerning V ˙ O 2 m a x . No significant effect of training with PR or HWB was observed for several variables (p > 0.05), including aerobic peak power output, the decline rate of jump height during 1 min-continuous maximal countermovement jumps (i.e. anaerobic capacity index), and the force-velocity relationship. Regarding specific tasks on ice, a small effect of training was found on both half-lap time and total time during a 1.5-lap all-out exercise (p = 0.0487; d = 0.23 and p = 0.0332; d = 0.21, respectively) but no additional effect of HWB was observed. In summary, the regular HWB protocol used in this study can induce additional effects on maximal isometric strength without compromising aerobic and anaerobic adaptations or field performance in these athletes.

Mechanical, Cardiorespiratory, and Muscular Oxygenation Responses to Sprint Interval Exercises Under Different Hypoxic Conditions in Healthy Moderately Trained Men.

Objective: The aim of this study was to determine the effects of sprint interval exercises (SIT) conducted under different conditions (hypoxia and blood flow restriction [BFR]) on mechanical, cardiorespiratory, and muscular O2 extraction responses. Methods: For this purpose, 13 healthy moderately trained men completed five bouts of 30 s all-out exercises interspaced by 4 min resting periods with lower limb bilateral BFR at 60% of the femoral artery occlusive pressure (BFR60) during the first 2 min of recovery, with gravity-induced BFR (pedaling in supine position; G-BFR), in a hypoxic chamber (FiO2≈13%; HYP) or without additional stress (NOR). Peak and average power, time to achieve peak power, rating of perceived exertion (RPE), and a fatigue index (FI) were analyzed. Gas exchanges and muscular oxygenation were measured by metabolic cart and NIRS, respectively. Heart rate (HR) and peripheral oxygen saturation (SpO2) were continuously recorded. Results: Regarding mechanical responses, peak and average power decreased after each sprint (p < 0.001) excepting between sprints four and five. Time to reach peak power increased between the three first sprints and sprint number five (p < 0.001). RPE increased throughout the exercises (p < 0.001). Of note, peak and average power, time to achieve peak power and RPE were lower in G-BFR (p < 0.001). Results also showed that SpO2 decreased in the last sprints for all the conditions and was lower for HYP (p < 0.001). In addition, Δ[O2Hb] increased in the last two sprints (p < 0.001). Concerning cardiorespiratory parameters, BFR60 application induced a decrease in gas exchange rates, which increased after its release compared to the other conditions (p < 0.001). Moreover, muscle blood concentration was higher for BFR60 (p < 0.001). Importantly, average and peak oxygen consumption and muscular oxyhemoglobin availability during sprints decreased for HYP (p < 0.001). Finally, the tissue saturation index was lower in G-BFR. Conclusions: Thus, SIT associated with G-BFR displayed lower mechanical, cardiorespiratory responses, and skeletal muscle oxygenation than the other conditions. Exercise with BFR60 promotes higher blood accumulation within working muscles, suggesting that BFR60 may additionally affect cellular stress. In addition, HYP and G-BFR induced local hypoxia with higher levels for G-BFR when considering both exercise bouts and recovery periods.

Mass-normalized internal mechanical work in walking is not impaired in adults with class III obesity.

This study aimed to investigate the effects of obesity on the internal mechanical work, and its influence on the total mechanical work, energy cost, and mechanical efficiency in obese and nonobese adults while walking at different speeds. Body composition and anthropometrical characteristics were obtained for eleven obese [O; 39.9 ± 7.9 yr; body mass index (BMI): 43.0 ± 4.2 kg/m2] and thirteen lean adults (L; 29.6 ± 5.7 yr; BMI: 22.0 ± 1.5 kg/m2). Participants walked at five speeds (0.56, 0.83, 1.11, 1.39, 1.67 m/s) while oxygen consumption was measured to obtain net energy cost of walking (NCw). A motion analysis system and instrumented treadmill were combined to obtain external (Wext), internal (Wint), and total (Wtot) mechanical work, and pendular energy recovery. Mechanical efficiency was calculated as the ratio of Wtot to NCw. Relative NCw (per unit body mass) was significantly higher in O than L (P ≤ 0.001). Relative Wext was significantly lower in O compared with L (P = 0.002), whereas no significant difference was found in relative Wint (P = 0.16) and Wtot (P = 0.6). Recovery was significantly higher (P ≤ 0.001), while mechanical efficiency was significantly lower in O than in L (P ≤ 0.001). These results suggest that individuals with obesity class III have similar mass-normalized Wint and Wtot compared with their lean counterparts, along with a higher relative NCw. Consequently, the efficiency of walking was reduced in this population. These results suggest that mass-normalized Wint is unaffected by obesity and is not responsible for the higher relative NCw and lower efficiency of walking in these individuals.NEW & NOTEWORTHY It has been suggested that internal mechanical work (i.e., the work required to move the limbs with respect to the center of mass, Wint) may be responsible for the higher net cost of walking in obese adults, but this variable has not yet been studied in individuals with obesity. The main finding of the present study is that individuals with class III obesity exhibit a similar amount of mass-normalized Wint to that of adults with a normal body weight, suggesting that body mass-relative Wint is not affected by obesity and is not responsible for the higher energy cost and the lower efficiency of walking in this population.

Alterations to neuromuscular properties of skeletal muscle are temporally dissociated from the oxygen uptake slow component.

To assess if the alteration of neuromuscular properties of knee extensors muscles during heavy exercise co-vary with the SCV ([Formula: see text] slow component), eleven healthy male participants completed an incremental ramp test to exhaustion and five constant heavy intensity cycling bouts of 2, 6, 10, 20 and 30 minutes. Neuromuscular testing of the knee extensor muscles were completed before and after exercise. Results showed a significant decline in maximal voluntary contraction (MVC) torque only after 30 minutes of exercise (-17.01% ± 13.09%; p < 0.05) while single twitch (PT), 10 Hz (P10), and 100 Hz (P100) doublet peak torque amplitudes were reduced after 20 and 30 minutes (p < 0.05). Voluntary activation (VA) and M-wave were not affected by exercise, but significant correlation was found between the SCV and PT, MVC, VA, P10, P100, and P10/P100 ratio, respectively (p < 0.015). Therefore, because the development of the SCV occurred mainly between 2-10 minutes, during which neuromuscular properties were relatively stable, and because PT, P10 and P100 were significantly reduced only after 20-30 minutes of exercise while SCV is stable, a temporal relationship between them does not appear to exist. These results suggest that the development of fatigue due to alterations of neuromuscular properties is not an essential requirement to elicit the SCV.

The metabolic profiles of different fiber type populations under the emergence of the slow component of oxygen uptake.

To investigate the influence of different metabolic muscle fiber profiles on the emergence of the slow component of oxygen uptake ([Formula: see text]SC), 12 habitually active males completed four sessions of different combinations of work-to-work transition exercises up to severe intensity. Each transition was modeled to analyze the different kinetic parameters. Using a new approach, combining Henneman's principle and superposition principle, a reconstructed kinetics was built by temporally aligning the start of each new transition and summing them. The primary phase time constant significantly slowed and the gain at the end (GainEnd) significantly increased when transitions started from a higher intensity (p < 0.001). Kinetic parameters from the reconstructed curve ([Formula: see text], time delay of primary phase, [Formula: see text]End and GainEnd) were not significantly different from one transition to severe exercise. These results suggest that the appearance of the [Formula: see text]SC is at least related to, if not the result of, the different metabolic properties of muscle fibers.