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1.
Biomed Microdevices ; 19(1): 9, 2017 03.
Article de Anglais | MEDLINE | ID: mdl-28127655

RÉSUMÉ

In this work, we discuss and demonstrate the principle features of surface acoustic wave (SAW) aerosol generation, based on the properties of the fluid supply, the acoustic wave field and the acoustowetting phenomena. Furthermore, we demonstrate a compact SAW-based aerosol generator amenable to mass production fabricated using simple techniques including photolithography, computerized numerical control (CNC) milling and printed circuit board (PCB) manufacturing. Using this device, we present comprehensive experimental results exploring the complexity of the acoustic atomization process and the influence of fluid supply position and geometry, SAW power and fluid flow rate on the device functionality. These factors in turn influence the droplet size distribution, measured here, that is important for applications including liquid chromatography, pulmonary therapies, thin film deposition and olfactory displays.


Sujet(s)
Acoustique/instrumentation , Aérosols , Conception d'appareillage
2.
Article de Anglais | MEDLINE | ID: mdl-21097030

RÉSUMÉ

In this paper a new tool to assess viscoelastic and dielectric properties of human fluids is presented. Shear horizontal polarized surface acoustic waves (SH-SAW) are used to detect the viscoelastic properties of coagulating blood and blood plasma samples. One-port SAW resonators, with fundamental modes of 85, 170 und 340 MHz were developed. Additionally, their electrode structures can be used simultaneously to detect the dielectric behavior of the whole system by impedance spectroscopy while the frequency ranges from kHz to MHz. The combination of both methods offers the detection of clinical relevant blood parameters like the blood coagulation time and the hematocrit value within one measurement.


Sujet(s)
Acoustique/instrumentation , Techniques de biocapteur/instrumentation , Analyse chimique du sang/instrumentation , Mélanges complexes/sang , Systèmes micro-électro-mécaniques/instrumentation , Conception d'appareillage , Analyse de panne d'appareillage
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