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1.
Behav Res Ther ; 180: 104594, 2024 Sep.
Article de Anglais | MEDLINE | ID: mdl-38945041

RÉSUMÉ

Dialectical Behaviour Therapy (DBT) is an evidence-based treatment for borderline personality disorder (BPD), with findings demonstrating improvements in various BPD features and related behaviours, such as nonsuicidal self-injury (NSSI). Theory and research suggest that reductions in emotion dysregulation and interpersonal dysfunction could account for at least some of the reduction in NSSI observed during the course of DBT. The current research investigated: 1) the trajectory of changes in emotion dysregulation, interpersonal dysfunction, and NSSI over the course of DBT, and 2) whether changes in emotion dysregulation mediate the relationship between changes in interpersonal dysfunction and changes in NSSI over treatment. One hundred and twenty individuals with BPD enrolled in a multi-site randomized-clinical trial were assessed at five timepoints over 12 months of standard DBT. Results indicated that interpersonal dysfunction and NSSI decreased over the course of DBT. Emotion dysregulation decreased in a quadratic manner such that most of the gains in emotion dysregulation occurred in earlier phases of DBT. Although changes in interpersonal dysfunction predicted changes in emotion dysregulation, changes in emotion dysregulation did not mediate the relationship between changes in interpersonal dysfunction and changes in NSSI.


Sujet(s)
Trouble de la personnalité limite , Thérapie comportementale dialectique , Régulation émotionnelle , Relations interpersonnelles , Comportement auto-agressif , Humains , Trouble de la personnalité limite/thérapie , Trouble de la personnalité limite/psychologie , Comportement auto-agressif/psychologie , Comportement auto-agressif/thérapie , Femelle , Adulte , Mâle , Régulation émotionnelle/physiologie , Jeune adulte , Résultat thérapeutique , Adolescent , Adulte d'âge moyen
2.
J Surg Educ ; 81(1): 134-144, 2024 Jan.
Article de Anglais | MEDLINE | ID: mdl-37926660

RÉSUMÉ

OBJECTIVE: Emergency department thoracotomy (EDT) is an uncommon but potentially lifesaving procedure that warrants familiarity with anatomy, instruments, and indications necessary for completion. To address this need, we developed a low-cost EDT trainer. The primary objective of this study was to compare the effectiveness of a low-cost EDT trainer to teach emergency department thoracotomy with a discussion-based teaching session. Secondary objective was to study the face validity of the low-cost EDT trainer. DESIGN: A prospective 2-phase randomized control study was conducted. Participants were randomly divided into two groups. In phase one, baseline medical knowledge for both groups was assessed using a multiple-choice question pretest. In Group 1, each participant was taught EDT using a one-on-one discussion with a trauma surgeon, whereas Group 2 used the EDT trainer and debriefing for training. In phase 2 (1 month later), all participants completed a knowledge retention test and performed a videoed EDT using our EDT trainer, the video recordings were later reviewed by content experts blinded to the study participants using a checklist with a maximum score of 22. The participants also completed a reaction survey at the end of phase 2 of the study. SETTING: OhioHealth Riverside Methodist Hospital, an urban tertiary care academic hospital in Columbus, Ohio. PARTICIPANTS: Nine senior surgery residents from training years 3 to 5. RESULTS: The mean score for the performance of the procedure for the simulation-based (Group 2) was significantly higher than that of the discussion-based (Group 1) (Rater 1: 21.2 ± 0.8 vs. 19.0 ± 2.0, p = 0.05, Rater 2: 20.4 ± 1.5 vs. 18.3±1.0, p = 0.04). Group 2 also was quicker than Group 1 in deciding to start the procedure by approximately 56 seconds. When comparing the mean pretest knowledge score to the mean knowledge retention score 30 days after training, the discussion-based group improved from 58.33% to 81.25% (p = 0.01); the simulation-trained group's scores remained at 68.33%. All the participants agreed or strongly agreed that the simulator provided a realistic opportunity to perform EDT and improved their confidence. CONCLUSIONS: The results of this pilot study support our hypothesis that using a low-cost EDT trainer effectively improves general surgery residents' confidence and procedural skills scores in a simulated environment. Further training with low-cost simulators may provide surgical residents with deliberate practice opportunities and improve performance when learning low-frequency procedures.


Sujet(s)
Chirurgie générale , Internat et résidence , Humains , Thoracotomie/enseignement et éducation , Projets pilotes , Études prospectives , Service hospitalier d'urgences , Compétence clinique , Chirurgie générale/enseignement et éducation
3.
Personal Disord ; 15(2): 134-145, 2024 Mar.
Article de Anglais | MEDLINE | ID: mdl-38059949

RÉSUMÉ

Despite nearly 30 years of research demonstrating its effectiveness in the treatment of borderline personality disorder (BPD) and related problems, few studies have investigated mechanisms of change for dialectical behavior therapy (DBT; Linehan, 1993a). Improvements in mindfulness and emotion regulation have been highlighted as key potential mechanisms of change in DBT (Lynch et al., 2006). The present study examined the time course of and associations between mindfulness, emotion regulation, and BPD symptoms during DBT. Participants were 240 repeatedly and recently self-harming adults (Mage = 27.75) with BPD who were randomly assigned to receive either 6 or 12 months of standard DBT. Primary hypotheses were that: (a) changes in mindfulness would occur before changes in emotion regulation, and (b) changes in emotion regulation would mediate the association of changes in mindfulness with changes in BPD symptoms. Results from changepoint analysis illuminated the proportion of participants for whom first changes occurred in emotion regulation (40.7%), mindfulness (32.4%), or both (26.9%). Contrary to hypotheses, five-wave, cross-lagged analyses did not indicate mediational effects of either mindfulness or emotion regulation on the association of either variable with change in BPD symptoms. Supplemental analyses, however, suggested that changes in emotion regulation mediated the inverse association of changes in mindfulness with changes in BPD symptoms. Findings highlight patterns of change in key, proposed mechanisms of change in DBT and suggest important future research directions. (PsycInfo Database Record (c) 2024 APA, all rights reserved).


Sujet(s)
Trouble de la personnalité limite , Thérapie comportementale dialectique , Régulation émotionnelle , Pleine conscience , Adulte , Humains , Trouble de la personnalité limite/thérapie , Trouble de la personnalité limite/psychologie , Thérapie comportementale/méthodes , Résultat thérapeutique
4.
Psychol Med ; 54(7): 1350-1360, 2024 May.
Article de Anglais | MEDLINE | ID: mdl-37997387

RÉSUMÉ

BACKGROUND: Recent findings suggest that brief dialectical behavior therapy (DBT) for borderline personality disorder is effective for reducing self-harm, but it remains unknown which patients are likely to improve in brief v. 12 months of DBT. Research is needed to identify patient characteristics that moderate outcomes. Here, we characterized changes in cognition across brief DBT (DBT-6) v. a standard 12-month course (DBT-12) and examined whether cognition predicted self-harm outcomes in each arm. METHODS: In this secondary analysis of 240 participants in the FASTER study (NCT02387736), cognitive measures were administered at pre-treatment, after 6 months, and at 12 months. Self-harm was assessed from pre-treatment to 2-year follow-up. Multilevel models characterized changes in cognition across treatment. Generalized estimating equations examined whether pre-treatment cognitive performance predicted self-harm outcomes in each arm. RESULTS: Cognitive performance improved in both arms after 6 months of treatment, with no between-arm differences at 12-months. Pre-treatment inhibitory control was associated with different self-harm outcomes in DBT-6 v. DBT-12. For participants with average inhibitory control, self-harm outcomes were significantly better when assigned to DBT-12, relative to DBT-6, at 9-18 months after initiating treatment. In contrast, participants with poor inhibitory control showed better self-harm outcomes when assigned to brief DBT-6 v. DBT-12, at 12-24 months after initiating treatment. CONCLUSIONS: This work represents an initial step toward an improved understanding of patient profiles that are best suited to briefer v. standard 12 months of DBT, but observed effects should be replicated in a waitlist-controlled study to confirm that they were treatment-specific.


Sujet(s)
Trouble de la personnalité limite , Thérapie comportementale dialectique , Comportement auto-agressif , Humains , Trouble de la personnalité limite/psychologie , Résultat thérapeutique , Comportement auto-agressif/thérapie , Comportement auto-agressif/psychologie , Listes d'attente , Thérapie comportementale
5.
Behav Ther ; 54(5): 876-891, 2023 09.
Article de Anglais | MEDLINE | ID: mdl-37597964

RÉSUMÉ

The COVID-19 pandemic has created a burden on healthcare systems and increased demand for mental healthcare at a time when in-person services are limited. Many programs offering dialectical behavior therapy (DBT) for complex clients have pivoted to telehealth in order to increase access to critical mental healthcare. There is, however, limited research on the provision of telehealth treatment for clients with complex psychopathology more broadly, or the telehealth implementation of DBT more specifically. The aim of this study was to examine the use of telehealth services and related clinician attitudes and experiences in the context of DBT. We examined the degree of telehealth platform adoption among DBT clinicians, as well as changes in stress and self-care strategies. A supplemental aim was to gather clinicians' recommendations for providing DBT via telehealth. Participants included N = 99 DBT practitioners (79.8% female; 20.2% male). Qualitative and quantitative methods were used for data analysis. Findings show that telehealth DBT has been widely adopted among DBT clinicians, and that clinicians' attitudes to telehealth DBT are cautiously optimistic. Participants described three main areas of stress associated with DBT via telehealth provision, as well as lost and novel self-care strategies.


Sujet(s)
COVID-19 , Thérapie comportementale dialectique , Télémédecine , Femelle , Mâle , Humains , Pandémies , Autosoins
6.
Curr Psychiatry Rep ; 25(5): 223-231, 2023 05.
Article de Anglais | MEDLINE | ID: mdl-37036627

RÉSUMÉ

PURPOSE OF REVIEW: This manuscript aims to take stock of emotion dysregulation and personality disorder (PD) research, review key findings, and highlight future directions. RECENT FINDINGS: Most emotion dysregulation research in PDs has focused on borderline personality disorder (BPD). BPD is characterized by high baseline negative emotion and the use of maladaptive emotion regulation strategies, but several other emotion dysregulation components may not be pervasively evident in the disorder. Trends in the BPD field that add nuance to the study of emotion dysregulation suggest that BPD may involve problems in the flexible, contextually based selection/implementation of emotion regulation strategies, as well as the development of appropriate emotion regulatory goals. Furthermore, relational stressors may elicit and maintain emotion dysregulation in BPD. Less research has examined emotion dysregulation in other PDs, but several PDs may involve deficits in emotional processes (e.g., lower behavioral inhibition and resistance of emotion-related impulses), particularly in interpersonal contexts. Emotion dysregulation is a nuanced and contextual problem which, for some PDs, may be particularly nested within interpersonal contexts. The BPD field and the increasing nuance of the study of emotion dysregulation within it points to key future research directions for the broader PD field.


Sujet(s)
Trouble de la personnalité limite , Régulation émotionnelle , Humains , Troubles de la personnalité , Émotions/physiologie , Trouble de la personnalité limite/psychologie
7.
Psychiatry Res ; 323: 115131, 2023 05.
Article de Anglais | MEDLINE | ID: mdl-36905903

RÉSUMÉ

Borderline personality disorder (BPD) is characterized by instability in interpersonal, affective, cognitive, self-identity, and behavioral domains. For a BPD diagnosis, individuals must present at least five of nine symptoms, resulting in 256 possible symptom combinations; thus, individuals diagnosed with BPD can differ substantially. Specific symptoms of BPD tend to co-occur, suggesting BPD subgroups. To explore this potential, we analyzed data from 504 participants diagnosed with BPD enrolled in one of three randomized controlled trials conducted at center for Addiction and Mental Health in Toronto, Canada from 2002 to 2018. An exploratory latent class analysis (LCA) was conducted to identify symptom subgroups of BPD. Analyses indicated three latent subgroups. The first group (n = 53) is distinguished by a lack of affective instability and low levels of dissociative symptoms (non-labile type). The second group (n = 279) is characterized by high levels of dissociative and paranoid symptoms but low abandonment fears and identity disturbance (dissociative/paranoid type). The third group (n = 172) is characterized by high efforts to avoid abandonment and interpersonal aggression (interpersonally unstable type). Homogenous symptom subgroups of BPD symptoms exist and may have important implications for how to refine BPD treatment interventions.


Sujet(s)
Trouble de la personnalité limite , Humains , Trouble de la personnalité limite/psychologie , Analyse de structure latente , Agressivité , Santé mentale , Troubles dissociatifs/psychologie
8.
World J Urol ; 41(3): 757-765, 2023 Mar.
Article de Anglais | MEDLINE | ID: mdl-36692533

RÉSUMÉ

PURPOSE: Nephroureterectomy(NU) remains the gold-standard surgical option for the management of upper urinary tract urothelial carcinoma(UTUC). Controversy exists regarding the optimal excision technique of the lower ureter. We sought to compare post-UTUC bladder tumour recurrence across the Scottish Renal Cancer Consortium(SRCC). METHODS: Patients who underwent NU for UTUC across the SRCC 2012-2019 were identified. The impact of lower-end surgical technique along with T-stage, N-stage, tumour location and focality, positive surgical margin, pre-NU ureteroscopy, upper-end technique and adjuvant mitomycin C administration were assessed by Kaplan-Meier and Cox-regression. The primary outcome was intra-vesical recurrence-free survival (B-RFS). RESULTS: In 402 patients, the median follow-up was 29 months. The lower ureter was managed by open transvesical excision in 90 individuals, transurethral and laparoscopic dissection in 76, laparoscopic or open extra-vesical excision in 31 and 42 respectively, and transurethral dissection and pluck in 163. 114(28.4%) patients had a bladder recurrence during follow-up. There was no difference in B-RFS between lower-end techniques by Kaplan-Meier (p = 0.94). When all factors were taken into account by adjusted Cox-regression, preceding ureteroscopy (HR 2.65, p = 0.001), lower ureteric tumour location (HR 2.16, p = 0.02), previous bladder cancer (HR 1.75, p = 0.01) and male gender (HR 1.61, p = 0.03) were associated with B-RFS. CONCLUSION: These data suggest in appropriately selected patients, lower ureteric management technique does not affect B-RFS. Along with lower ureteric tumour location, male gender and previous bladder cancer, preceding ureteroscopy was associated with a higher recurrence rate following NU, and the indication for this should be carefully considered.


Sujet(s)
Néphrocarcinome , Carcinome transitionnel , Tumeurs du rein , Uretère , Tumeurs de l'uretère , Tumeurs de la vessie urinaire , Humains , Mâle , Uretère/chirurgie , Uretère/anatomopathologie , Carcinome transitionnel/anatomopathologie , Études rétrospectives , Récidive tumorale locale/anatomopathologie , Tumeurs de l'uretère/anatomopathologie , Tumeurs du rein/chirurgie , Écosse/épidémiologie
9.
Death Stud ; 47(9): 1044-1052, 2023.
Article de Anglais | MEDLINE | ID: mdl-36576153

RÉSUMÉ

The growing use of digitized mental health applications requires new reliable early screening tools to identify user suicide risk. We used a lexicon-based random forest machine learning algorithm to predict suicide ideation scores from 714 online community text posts from December 2019 to April 2020. We validated predicted scores against expert-rated suicide ideation scores. The algorithm-predicted scores offered high validity and a low error rate and correctly identified 95% of expert-rated high-risk suicide ideation posts. Our findings highlight a potential new method to detect suicidal ideation of digital mental health application users.


Sujet(s)
Santé mentale , Idéation suicidaire , Humains , Forêts aléatoires , Facteurs de risque
10.
Psychother Psychosom ; 91(6): 382-397, 2022.
Article de Anglais | MEDLINE | ID: mdl-35738244

RÉSUMÉ

INTRODUCTION: Evidence-based psychotherapies for borderline personality disorder (BPD) are lengthy, posing a barrier to their access. Brief psychotherapy may achieve comparable outcomes to long-term psychotherapy for BPD. Evidence is needed regarding the comparative effectiveness of short- versus long-term psychotherapy for BPD. OBJECTIVE: The aim was to determine if 6 months of Dialectical Behavior Therapy (DBT) is noninferior to 12 months of DBT in terms of clinical effectiveness. METHODS: This two-arm, single-blinded, randomized controlled noninferiority trial with suicidal or self-harming patients with BPD was conducted at two sites in Canada. Participants (N = 240, M (SD)age = 28.27 (8.62), 79% females) were randomized to receive either 6 (DBT-6) or 12 months (DBT-12) of comprehensive DBT. Masked assessors obtained measures of clinical effectiveness at baseline and every 3 months, ending at month 24. DBT-6 and DBT-12 were outpatient treatments consisting of weekly individual therapy sessions, weekly DBT skills training group sessions, telephone consultation as needed, and weekly therapist consultation team meetings. RESULTS: The noninferiority hypothesis was supported for the primary outcome, total self-harm (6 months: margin = -1.94, Mdiff [95% CI] = 0.16 [-0.14, 0.46]; 12 months: margin = -1.47, Mdiff [95% CI] = 0.04 [-0.17, 0.23]; 24 months: margin = -1.25, Mdiff [95% CI] = 0.12 [-0.02, 0.36]). Results also supported noninferiority of DBT-6 for general psychopathology and coping skills at 24 months. Furthermore, DBT-6 participants showed more rapid reductions in BPD symptoms and general psychopathology. There were no between-group differences in dropout rates. CONCLUSIONS: The noninferiority of a briefer yet comprehensive treatment for BPD has potential to reduce barriers to treatment access.


Sujet(s)
Trouble de la personnalité limite , Thérapie comportementale dialectique , Comportement auto-agressif , Femelle , Humains , Adulte , Mâle , Thérapie comportementale dialectique/méthodes , Trouble de la personnalité limite/thérapie , Orientation vers un spécialiste , Téléphone , Psychothérapie/méthodes , Comportement auto-agressif/thérapie , Résultat thérapeutique , Thérapie comportementale/méthodes
11.
J Health Soc Behav ; 63(2): 191-209, 2022 06.
Article de Anglais | MEDLINE | ID: mdl-35392693

RÉSUMÉ

The study of social networks is increasingly central to health research for medical sociologists and scholars in other fields. Here, we review the innovations in theory, substance, data collection, and methodology that have propelled the study of social networks and health from a niche subfield to the center of larger sociological and scientific debates. In particular, we contextualize the broader history of network analysis and its connections to health research, concentrating on work beginning in the late 1990s, much of it in this journal. Using bibliometric and network visualization approaches, we examine the subfield's evolution over this period in terms of topics, trends, key debates, and core insights. We conclude by reflecting on persistent challenges and areas of innovation shaping the study of social networks and health and its intersection with medical sociology in the coming years.


Sujet(s)
Sociologie médicale , Sociologie , Humains , Réseautage social , Sociologie/histoire
12.
Suicide Life Threat Behav ; 52(5): 836-847, 2022 10.
Article de Anglais | MEDLINE | ID: mdl-35385177

RÉSUMÉ

OBJECTIVE: Behavioral models of nonsuicidal self-injury (NSSI) propose that experiencing desirable consequences following NSSI reinforces the behavior. However, these models do not specify whether experiencing more desirable consequences relative to other people (between-person), an individual's own average (within-person), or both, predicts NSSI severity. To address this gap, this study investigated the prospective, within- and between-person associations of desirable NSSI consequences with NSSI frequency (number of episodes) and versatility (number of methods). METHODS: Two hundred and ten individuals (93.81% female, Mage  = 22.95) with a history of NSSI completed online surveys assessing NSSI consequences, frequency, and versatility every three months for one year. RESULTS: Within-person increases in desirable emotional consequences were unrelated to NSSI frequency three months later but predicted increases in NSSI versatility. Within-person increases in desirable social consequences predicted decreases in NSSI frequency three months later but were unrelated to NSSI versatility. Between-person variability in desirable consequences was unrelated to NSSI severity. CONCLUSIONS: Findings were partially consistent with behavioral models of NSSI. Going forward, we recommend that: (1) behavioral models articulate the salience of within-person fluctuations in consequences; (2) research clarifies the role of social consequences; and (3) clinicians use repeated assessments of emotional consequences to identify periods of elevated NSSI risk.


Sujet(s)
Comportement auto-agressif , Humains , Femelle , Jeune adulte , Adulte , Mâle , Études prospectives , Comportement auto-agressif/psychologie , Relations interpersonnelles , Émotions , Enquêtes et questionnaires
13.
Suicide Life Threat Behav ; 52(4): 812-827, 2022 08.
Article de Anglais | MEDLINE | ID: mdl-35362639

RÉSUMÉ

INTRODUCTION: People report multiple motives for nonsuicidal self-injury (NSSI), but few studies have examined how these motives relate to one another. This study identified person-centered classes of NSSI motives, their NSSI and psychopathological correlates, and their utility in predicting future NSSI across two samples. METHODS: Participants were adolescents and young adults (aged 15-35) with recent NSSI recruited from online forums (n = 155, Sample 1) or the community (n = 127, Sample 2). Participants completed measures of NSSI, emotion regulation difficulties, borderline personality disorder (BPD), depression, and reported on their NSSI over 12 months. RESULTS: Latent profile analyses yielded five classes in each sample: low interpersonal, self-punishment/interpersonal, moderate intra/interpersonal, high intra/interpersonal, and mainly interpersonal motives. Classes were not associated with lifetime NSSI characteristics, but highly motivated participants reported more severe depression and BPD symptoms, and greater emotion dysregulation than low-motivated participants. Those in the mainly interpersonal (Sample 1) and self-punishment/interpersonal (Sample 2) motives classes reported greater NSSI frequency during follow-up. CONCLUSIONS: This study identified five classes of NSSI motives. Participants who report multiple motives for NSSI may be more clinically severe, whereas those who report strong desires to communicate with others or punish themselves may be at the highest risk for more frequent NSSI over time.


Sujet(s)
Trouble de la personnalité limite , Comportement auto-agressif , Adolescent , Trouble de la personnalité limite/diagnostic , Trouble de la personnalité limite/psychologie , Humains , Motivation , Psychopathologie , Comportement auto-agressif/diagnostic , Comportement auto-agressif/psychologie , Jeune adulte
14.
J Clin Psychol ; 78(11): 2329-2340, 2022 11.
Article de Anglais | MEDLINE | ID: mdl-35390173

RÉSUMÉ

OBJECTIVES: Emotional and interpersonal dysfunction appears central to nonsuicidal self-injury (NSSI), yet research examining the interplay of these factors among individuals with NSSI is limited. This study aimed to specify such associations before and after daily stressful events among individuals with (vs. without) NSSI. METHODS: Young adult participants (Mage = 20.4) with past-year (n = 56) or no history (n = 47) of NSSI completed daily diary assessments over a 2-week period. RESULTS: No differences in rates of positive or negative interpersonal experiences before or after stressful events were identified. NSSI participants, however, reported greater negative emotion following stressful events compared with non-NSSI participants. The presence (vs. absence) of a positive interpersonal experience following a stressful event was related to lower negative emotional responses only in the NSSI group. CONCLUSION: Positive interpersonal experiences may downregulate negative emotions following stressful events among individuals with NSSI, highlighting the potential relevance of interpersonal emotion regulation to this population.


Sujet(s)
Comportement auto-agressif , Adulte , Émotions , Humains , Comportement auto-agressif/psychologie , Jeune adulte
15.
Arch Suicide Res ; 26(2): 565-580, 2022.
Article de Anglais | MEDLINE | ID: mdl-32866425

RÉSUMÉ

OBJECTIVE: Although once considered a defining feature of borderline personality disorder, research has found high rates of NSSI among individuals with other psychiatric disorders, particularly posttraumatic stress disorder (PTSD) and depressive disorders. A recent study from our research team found that lifetime PTSD and depressive disorders were associated with unique self-reported NSSI motives. Given well-established limitations of assessing motives via self-report measures, the present study sought to extend this line of research by using a novel laboratory measure of the implicit NSSI-relief association to examine NSSI emotional relief motives. METHOD: A subset of participants from our previous study (N = 109) completed diagnostic interviews and the laboratory-based DSH-Relief Implicit Association Test (IAT). RESULTS: Findings indicated that individuals with lifetime PTSD evidenced stronger NSSI-relief associations than those without PTSD. Further, this main effect was qualified by a PTSD by depressive disorder interaction, such that stronger NSSI-relief associations were found among individuals with lifetime PTSD but no lifetime depressive disorder than among individuals without a history of either PTSD or a depressive disorder. CONCLUSIONS: Results highlight the importance of investigating NSSI motives associated with different symptom profiles using a multi-method approach.


Sujet(s)
Trouble de la personnalité limite , Trouble dépressif , Comportement auto-agressif , Troubles de stress post-traumatique , Trouble de la personnalité limite/psychologie , Humains , Motivation , Comportement auto-agressif/psychologie , Troubles de stress post-traumatique/psychologie
16.
J Sports Med Phys Fitness ; 62(8): 1078-1087, 2022 Aug.
Article de Anglais | MEDLINE | ID: mdl-34275261

RÉSUMÉ

BACKGROUND: Adolescent females are particularly susceptible to suffering anterior cruciate ligament (ACL) injuries, likely influenced by well-established maturational changes. This study investigated ACL biomechanical injury risk factors and their association with biological maturation in females. METHODS: Thirty-five adolescent females (15±1 year) completed a series of maximum-effort 90° unanticipated cutting maneuvers. Established biomechanical ACL injury risk factors (including external knee abduction moments, knee abduction, hip abduction, knee flexion, ground reaction force) were derived from an optoelectronic motion analysis system and force platforms, with inter-limb asymmetries in these risk factors also computed. Biological maturation (percentage of predicted adult stature) was assessed using validated regression equations, incorporating anthropometric measures of participants and their biological parents. RESULTS: Significant bilateral asymmetries were observed with higher peak external knee abduction moments, higher ground reaction forces and less knee flexion (from 0-18% and 30-39% of contact) during the non-dominant vs. dominant cuts (effect sizes =0.36, 0.63 and 0.50, respectively). Maturation did not appear to influence these asymmetries; however, less hip abduction was observed (e.g., 21-51% of contact for dominant cuts) in more biologically-mature females. CONCLUSIONS: These results highlight a potential maturation-related change in cutting technique that may explain the apparent heightened ACL injury risk in this population. As females mature, training targeted at neuromuscular control of hip abductor (e.g. gluteal) muscle groups could potentially mitigate ACL injury risk.


Sujet(s)
Lésions du ligament croisé antérieur , Adolescent , Adulte , Lésions du ligament croisé antérieur/étiologie , Phénomènes biomécaniques , Femelle , Humains , Genou , Articulation du genou/physiologie , Facteurs de risque
17.
Drug Alcohol Depend ; 222: 108668, 2021 05 01.
Article de Anglais | MEDLINE | ID: mdl-33766441

RÉSUMÉ

BACKGROUND: The opioid crisis is widely felt in the United States. Scholarly attention to the crisis focuses on macro-level processes and largely neglects meso-level explanations such as family structure for opioid use behaviors. We hypothesize that married adults and adults with coresident children are at lower risk of misusing prescription pain relievers (PPR), using heroin, and using needles to inject heroin relative to adults from other family structures. METHOD: We used National Survey on Drug Use and Health data from 2002-2018 to test our hypotheses with multivariable logistic regression. RESULTS: We found that married adults have a lower predicted probability of each opioid use behavior relative to nonmarried adults across the study period. We also found that the presence of children is associated with reductions in all three outcomes especially for never married adults. CONCLUSION: Individuals from all family structures are vulnerable to the opioid crisis, but never married adults without coresident children ("disconnected adults") are especially susceptible to temporal fluctuations and drive the temporal trends in PPR misuse and heroin use. These findings suggest that ongoing demographic trends where disconnected adults are a growing population may result in future rises in opioid use disorders and mortality because of divestment from U.S. social safety nets. Future research should examine the role of U.S. policies that make disconnected adults especially vulnerable to developing opioid use disorders.


Sujet(s)
Troubles liés aux opiacés , Surdose , Adulte , Analgésiques morphiniques/usage thérapeutique , Enfant , Humains , Modèles logistiques , Mariage , Troubles liés aux opiacés/traitement médicamenteux , Troubles liés aux opiacés/épidémiologie , États-Unis/épidémiologie
18.
J Affect Disord ; 277: 631-639, 2020 12 01.
Article de Anglais | MEDLINE | ID: mdl-32905915

RÉSUMÉ

BACKGROUND: Despite theories that negative reinforcement in the form of relief from negative emotions maintains nonsuicidal self-injury (NSSI), no studies have examined the extent to which specific emotional consequences of NSSI predict the maintenance of NSSI over time or explain the greater risk for NSSI found among individuals with borderline personality disorder (BPD) pathology. This study examined whether specific emotional consequences of NSSI relate to the continuance of NSSI behavior over a 12-month period and explain the relation of baseline BPD pathology to future NSSI. METHODS: Participants with a history of recent repeated NSSI (N = 84) completed baseline measures of BPD pathology, NSSI, and the emotional antecedents and consequences of NSSI, including self-conscious emotions, undifferentiated negative affect, anger, emptiness, sadness, and anxiety; follow-up data on NSSI were collected every three months for one year. RESULTS: Of the emotional consequences of NSSI examined here, only self-conscious emotions significantly predicted the presence and frequency of NSSI during the 12-month follow-up period. Likewise, whereas BPD pathology was not directly associated with later NSSI, both overall BPD pathology and the specific BPD feature of identity problems were indirectly related to the presence of 12-month NSSI through the greater frequency of post-NSSI self-conscious emotions. LIMITATIONS: Emotional consequences of NSSI were assessed using a retrospective self-report measure. Only frequency, and not intensity, of emotions before and after NSSI were assessed. CONCLUSIONS: Results suggest a distinct role of post-NSSI self-conscious emotions in the maintenance of NSSI among individuals with and without BPD pathology.


Sujet(s)
Trouble de la personnalité limite , Comportement auto-agressif , Émotions , Humains , Études rétrospectives , Autorapport
19.
SSM Popul Health ; 12: 100663, 2020 Dec.
Article de Anglais | MEDLINE | ID: mdl-32995460

RÉSUMÉ

This study evaluates whether the associations between social integration, inflammation, and depressive symptoms vary by race/ethnicity in the United States. Our study includes 5,634 respondents age 40 and older from the National Health and Nutrition Examination Survey for 2005-2008. We fit multivariate logistic regression models with interactions between C-reactive protein (CRP) and race/ethnicity as well as social integration and race/ethnicity to test our hypotheses. We find that social integration and CRP operate independently in their associations with depressive symptoms by race/ethnicity. Higher levels of social integration are associated with lower predicted probability of depressive symptoms for White and Black populations. This association is not statistically significant for the Hispanic population. CRP is associated with depressive symptoms for the White population, but not the Black or Hispanic populations. Our results suggest that studying depressive symptoms, and other mental health outcomes, among the US population without considering variation by race/ethnicity may restrict scholarly understanding of health disparities. Population-based assessments of associations between physiological processes or social integration should consider whether these variables operate differently by race/ethnicity and work to explain why differences may emerge. Furthermore, interventions aimed at social integration may improve mental health among older adults in the United States; especially for the least socially integrated.

20.
Personal Ment Health ; 14(2): 227-239, 2020 05.
Article de Anglais | MEDLINE | ID: mdl-32056384

RÉSUMÉ

Individuals with borderline personality disorder (BPD) often experience deficits in social role functioning, which encompasses the ability to adhere to socially defined rules and norms of behaviour. Additionally, research suggests that coping styles influence the way individuals with BPD manage stress and that symptom presentation and functioning in individuals with BPD vary across genders. This study sought to explore these variables via moderated mediation, investigating the mediating influence of coping styles on the association between BPD symptoms and social role dysfunction and if these associations were further moderated by gender. Participants (N = 233) were outpatients attending a programme for personality dysfunction. Participants completed measures of BPD symptoms, coping styles and social role dysfunction. Moderated mediation indicated that for women, emotion-oriented coping and social diversion-oriented coping mediated the association between BPD symptoms and social dysfunction. While BPD symptoms were positively associated with emotion coping, which was positively associated with social role dysfunction, BPD symptoms were negatively associated with social diversion coping, which was negatively associated with social role dysfunction. For men, coping did not mediate the association between BPD symptoms and social role dysfunction. Our findings may indicate that social support and a healthy social network may play an important part in the ongoing social role functioning of women with BPD. From this, potential early therapeutic interventions targeting safe social engagement in times of stress may decrease the pervasive and persistent nature of social dysfunction in BPD. © 2020 John Wiley & Sons, Ltd.


Sujet(s)
Adaptation psychologique/physiologie , Trouble de la personnalité limite/physiopathologie , Émotions/physiologie , Fonctionnement psychosocial , Rôle , Réseautage social , Compétences sociales , Soutien social , Adulte , Humains , Adulte d'âge moyen , Facteurs sexuels
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