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Vet Parasitol ; 272: 40-43, 2019 Aug.
Article de Anglais | MEDLINE | ID: mdl-31395203

RÉSUMÉ

In this study we evaluated the efficacy of trichlorfon against Haemonchus contortus, monitoring its influence on blood parameters and plasma enzymes of lambs with haemonchosis. A lamb group was orally treated with trichlorfon at 100 mg kg-1 while the other group was untreated. Split-plot design analysis was performed with the lamb groups defined as plots while the subplots were the four periods (weeks) of collection. The trichlorfon treatment promoted a significant and effective reduction of fecal egg counts after one week, with efficacies > 99%. After 21 days of treatment, detected blood parameters and serum levels of plasma enzymes were normal. Additionally, serum albumin and urea concentrations increased to normal values, which were not observed in untreated lambs. The treatment with this organophosphate, using a correct oral administration, may represent an effective therapeutic alternative for sheep infected with multi resistant strain of H. contortus.


Sujet(s)
Infections à Haemonchus/médecine vétérinaire , Maladies des ovins/traitement médicamenteux , Trichlorfon/usage thérapeutique , Animaux , Anthelminthiques/usage thérapeutique , Protéines du sang/analyse , Enzymes/sang , Infections à Haemonchus/sang , Haemonchus , Numération des oeufs de parasites/médecine vétérinaire , Ovis , Maladies des ovins/sang
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