Clinical guidelines for exercise training.

Exercise training may be useful for a variety of patients with and without established cardiovascular disease. The degree to which a patient participates in a prescribed exercise program depends strongly on initial motivation. The primary care physician can provide appropriate reinforcement with careful explanation of the effects of exercise on cardiovascular and metabolic function. Exercise programs may be combined effectively with other life-style adjustments, including weight loss, blood pressure control, and discontinuation of smoking. As a single intervention factor, exercise cannot prevent the evolution of cardiovascular disease in multiple-risk patients. Exercise is best used in combination with a program of comprehensive cardiovascular risk factor modification.

Hemodynamic effects after conversion of arrhythmias.

Systemic and coronary hemodynamic parameters were determined during an arrhythmia and immediately after a direct current transthoracic shock given in an attempt to convert the arrhythmia to a sinus mechanism. No anesthesia or drugs were administered between the two studies. 16 patients with atrial fibrillation converted to sinus rhythm and five did not. In two patients with atrial flutter and one with supraventricular tachycardia, the arrhythmia was corrected. The arrhythmia persisted in a single patient with ventricular tachycardia. Utilizing each patient as his own control, we compared statistically various hemodynamic parameters before and after the shock. In addition, the group of patients whose atrial fibrillation terminated was compared to the group treated in the same manner but in which the atrial fibrillation persisted. Pressures in the right side of the heart decreased in both groups so that the changes appeared to be caused by factors associated with the transthoracic direct current shock or the catheterization procedure. The differences between those with atrial fibrillation who converted to sinus rhythm as compared to those who did not were a decrease in heart rate, an increase in stroke volume, and an increase in cardiac efficiency. There was no immediate effect on the cardiac output or coronary blood flow.