Design and Evaluation of a Technological Platform for Monitoring Patients with Dementia: Unifying Requirements from Mexican Day Centers.

The monitoring of patients with dementia who receive comprehensive care in day centers allows formal caregivers to make better decisions and provide better care to patients. For instance, cognitive and physical therapies can be tailored based on the current stage of disease progression. In the context of day centers of the Mexican Federation of Alzheimer, this work aims to design and evaluate Alzaid, a technological platform for assisting formal caregivers in monitoring patients with dementia. Alzaid was devised using a participatory design methodology that consisted in eliciting and validating requirements from 22 and 9 participants, respectively, which were unified to guide the construction of a high-fidelity prototype evaluated by 14 participants. The participants were formal caregivers, medical staff, and management. This work contributes a high-fidelity prototype of a technological platform for assisting formal caregivers in monitoring patients with dementia considering restrictions and requirements of four Mexican day centers. In general, the participants perceived the prototype as quite likely to be useful, usable, and relevant in the job of monitoring patients with dementia (p-value < 0.05). By evaluating and designing Alzaid that unifies requirements for monitoring patients of four day centers, this work is the first effort towards a standard monitoring process of patients with dementia in the context of the Mexican Federation of Alzheimer.

Determinantes de caries temprana de la infancia en niños en riesgo social / Determinants of early childhood caries in children at social risk

OBJETIVO: Determinar la prevalencia de caries temprana de la infancia en niños en riesgo social y analizar sus factores de riesgo asociados. MÉTODO: Se realizó un estudio descriptivo de corte transversal con 246 niños de 24 a 71 meses de edad, reclutados de 13 barrios marginales, en Santiago, Chile. Se utilizó un cuestionario para obtener información sobre etnia, peso al nacer, edad y educación de la madre, uso de biberón nocturno, cepillado de dientes y visitas dentales. La caries temprana de la infancia fue registrada de acuerdo a la definición aceptada por la Academia Americana de Pediatría Dental. Se utilizó un análisis de regresión logística múltiple para investigar la influencia de los factores de riesgo en la experiencia de caries. RESULTADOS: La prevalencia de caries temprana de la infancia fue de un 63%. Los análisis bivariados mostraron asociaciones entre etnicidad, educación de la madre, uso de biberón nocturno, visitas dentales y caries temprana de infancia. El modelo multivariado final, mostró que los niños cuyas madres tenían un bajo nivel de educación tenían mayores probabilidades de desarrollar caries temprana de la infancia. CONCLUSIÓN: Los niños estudiados tuvieron una alta prevalencia de caries temprana de la infancia, siendo la educación de la madre, el determinante más importante.

OBJECTIVE: The aim of the present study was to evaluate the prevalence of early childhood caries (ECC) among children at social risk and to analyze its associated determinants. METHOD: A cross-sectional study with 246 children aged 24 to 71 months, recruited from 13 different slums, below the poverty line, in Santiago, Chile was performed. An interviewer-administered questionnaire was used to obtain information from the parents on ethnicity, birth weight, mother's age and education, night bottle feeding, tooth brushing and dental visits. Early childhood caries was defined using the American Academic of Pediatric Dentistry criteria. Multiple logistic regression analysis with a stepwise selection procedure was used to investigate the influence of risk factors on the early childhood caries experience. RESULTS: The prevalence of early childhood caries was 63%. Bivariate analyses showed associations among ethnicity, mother's education, bottle feeding at night, dental visits and caries experience. The final multivariate model showed that children whose mothers had a low level of education were more likely to develop early childhood caries. CONCLUSIONS: The children at social risk studied had a high prevalence of early childhood caries, with the education of the mother as the most important determinant.

Eritema gyratum repens idiopático: presentación de un caso en una mujer joven / Idiopathic erythema gyratum repens: presentation of a case in a young woman

El eritema gyratum repens es una dermatosis muy infrecuente incluida dentro del abanico diagnóstico de las lesiones figuradas. Aparece sobre todo en varones entre la sexta y séptima décadas de vida. Clásicamente se ha relacionado con neoplasias, sobre todo de pulmón, esófago y mama. Sin embargo, en los últimos años se ha visto que aproximadamente el 30% de los casos no son paraneoplásicos, pudiendo deberse a fármacos, enfermedades reumáticas, manifestaciones atípicas de procesos cutáneos, e incluso ser idiopáticos, por lo que es importante realizar un adecuado proceso diagnóstico para filiar la etiología, y considerar un amplio diagnóstico diferencial. Presentamos el caso de una mujer de 40 años con lesiones eritematosas anulares concéntricas sugestivas de eritema gyratum repens, del tipo idiopático tras el correspondiente estudio diagnóstico.

Erythema gyratum repens is an unusual dermatosis included within the group of figurate lesions. It usually appears in men at the age of sixty or seventy. Classically it has been related to neoplasms, especially of the lung, esophagus and breast, however recently it has been seen that 30% of cases are not paraneoplastic approximately, and might be caused by drugs, rheumatologic diseases, atypical presentation of common skin diseases, and also it could be idiopathic, so it is important to carry out an adequate diagnostic process to determine the etiology, and to consider a broad differential diagnosis. We present the case of a 40-year-old woman with concentric annular erythematous lesions suggestive of idiopathic erythema gyratum repens after the diagnostic process

Tromboprofilaxis con heparinas de bajo peso molecular en trauma craneoencefálico severo: una revisión sistemática / Low-molecular-weight heparin thromboprophylaxis in severe cranioencephalic trauma: a systematic review

Objetivo: Revisar sistemáticamente la evidencia de la tromboprofilaxis con heparinas de bajo peso molecular en trauma craneoencefálico severo. Criterios de inclusión: Ensayos clínicos aleatorizados que incluyan: pacientes mayores de 15 años, que hayan sufrido un traumatismo craneal grave (Glasgow < 8), que comparen el uso de heparinas de bajo peso molecular (HBPM) con grupo control (otras medidas farmacológicas y mecánicas o la no profilaxis), que evalúe mortalidad a 6 meses, riesgo de sangrado y de eventos trombóticos. Métodos: Se buscó en las siguientes bases de datos MEDLINE, the Central Register of Controlled Trials (CENTRAL); PubMed, HINARI, EMBASE; Cochrane Injuries group y lista de referencia de los artículos. Resultados: En el grupo de HBPM y el control no hubo diferencia significativa en el pronóstico de mortalidad (RR [Riesgo Relativo] 0,88, 95% CI 0.34 to 2.26). No aumentó el riesgo de sangrados. No hubo diferencias relacionadas con el riesgo tromboembólico comparado con el grupo control. Conclusiones: En pacientes con trauma craneoencefálico severo la tromboprofilaxis con HBPM fue similar con otros métodos de profilaxis antitrombótica. Faltan estudios que demuestren la eficacia y seguridad de la profilaxis antitrombótica con HBPM.

Objective: To systematically review the evidence of thromboprophylaxis tos with Low Molecular Weight Heparin (LMWH) in severe traumatic brain injury. Study eligibility criteria: Randomized clinical Trials with Patients older than 15 years, had a severe traumatic brain injury (Glasgow coma scale < 8), that compared the use of LMWH with control group (no prophylaxis and other pharmacologic and/ or mechanical methods, that presented an estimate of mortality/disability prognosis 6 months after injury, risk of bleeding and thromboembolic events (PE, DTV). Methods: Searched MEDLINE, the Central Register of Controlled Trials (CENTRAL); PubMed, HINARI, EMBASE; Cochrane Injuries group and the reference lists of articles. Results: In the LMWH and control groups there was no difference in the prognosis of mortality (RR [Relative Risk] 0,88, 95% CI 0.34 to 2.26). Don’t rise the risk of bleeding. There was no difference in the risk from thromboembolic events compared to the control group. Conclusions: In patients with severe traumatic brain injury, the use of LMWH is similarly with other thromboprophylactics methods. There aren’t studies that demonstrate the efficacy and safety of antithrombotic prophylaxis with LMWH.

Epidemiological characterization of pediatric patients with status asthmaticus admitted to intensive care units.

Asthma morbidity and mortality have increased in the past two decades; Puerto Rican children have the highest prevalence of asthma in the United States. An asthma admission to PICU is a marker of asthma severity. This study describes the profile of the pediatric population admitted with status asthmaticus during a three year period to PICU at Hospital Episcopal San Lucas. An ambispective cohort chart review of 46 cases was performed; there was a mean average age of 6.2 years, male predominance (70%) and a strong family and personal history of asthma and allergies. 48% were classified as persistent asthmatics, only 19% of these received preventive mediation regimens. 72% of patients were covered under Puerto Rico's Health Care Reform and 28% had private insurance. Of the patients covered by Puerto Rico's Health Care Reform, classified as persistent asthmatics, 79% did not receive preventive treatment medication compared to 46% in private insurance. Background asthma management remains suboptimal in children needing hospitalization. Lack of preventive medication appears to be related to the type of health insurance.

Incidencia de los factores de riesgo de la hipertensión arterial grave inducida por el embarazo / Incidence of the risk factors of severe pregnancy induced hypertension

La presente investigación tuvo como propósito determinar la incidencia de los factores de riesgo de la hipertensión arterial grave inducida por el embarazo. Este estudio descriptivo transversal se circunscribe a 100 pacientes que cumplieron con los criterios diagnóstico establecidos. Los datos se recolectaron a través de un instrumento diseñado para tal fin. Los resultados revelaron que las pacientes más expuestas a presentar la enfermedad son pacientes comprendidas entre los 16 y 25 años, primigestas, con antecedentes de hipertensión gestacional, con antecedentes familiares de hipertención inducida por el embarazo, gestantes que cursan de 36 a 42 semanas, y las mujeres de clase sociológicamente bajo. Se recomienda: 1) centros de capacitación para el personal de los sistemas de salud; 2) programas comunitarios; 3) fortalecer los sistemas locales de salud y 4) adecuar los sistemas de referencia