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1.
Arch Pediatr ; 18(7): 767-71, 2011 Jul.
Article de Français | MEDLINE | ID: mdl-21565474

RÉSUMÉ

Acute necrotizing pneumonia due to Panton-Valentine secreting Staphylococcus aureus was identified as a clinical entity by Gilet et al., in 2002. This severe acute necrotizing pneumonia occurring in previously healthy children and adolescents can lead to a rapid fatal outcome even if quickly diagnosed and treated. We report the case of a healthy 10-year-old girl presenting with hemorrhagic necrotizing pneumonia and septic shock. Bacteriological cultures yielded methicillin-susceptible Staphylococcus aureus. The course of the disease was characterized by recurrent uncontrolled hemoptysia leading to refractory hypoxemia. The details of the hospital stay are presented. We discuss the clinical features of the disease and describe recent epidemiologic data and Panton-Valentine toxin research results as well as primary hospital care and treatment.


Sujet(s)
Infections communautaires/diagnostic , Exotoxines/métabolisme , Leucocidine/métabolisme , Pneumopathie à staphylocoques/diagnostic , Staphylococcus aureus/pathogénicité , Antibactériens/usage thérapeutique , Toxines bactériennes , Bronchoscopie , Enfant , Infections communautaires/microbiologie , Infections communautaires/thérapie , Soins de réanimation/méthodes , Association de médicaments , Issue fatale , Femelle , Hémoptysie/étiologie , Humains , Hypoxie/étiologie , Nécrose , Pneumopathie à staphylocoques/microbiologie , Pneumopathie à staphylocoques/thérapie , Choc septique/diagnostic , Choc septique/microbiologie , Virulence
3.
J Gynecol Obstet Biol Reprod (Paris) ; 38(4): 277-85, 2009 Jun.
Article de Français | MEDLINE | ID: mdl-19386447

RÉSUMÉ

The prenatal diagnosis of abdominal mass poses the problem of its origin. Renal tumors are rarer than neuroblastoma but they are most often congenital mesoblastic nephroma. The congenital mesoblastic nephroma has a good forecast in spite of a sonographic impressive aspect. MRI can help to locate tumor but cannot tell difference between the different kinds of renal tumor. Prenatal forecast is especially linked with hydramnios and hydrops fetalis. Histolological study of the tumor is important for the prognosis. Two morphological subtypes are currently distinguished: the classic type with a good forecast and the atypical or cellular type. Distant metastases have been related only to the cellular form but especially in infants aged more than 3 months and never in the newborns. The diagnosis of the tumor does not change the mode of delivery except in case of an important volume. Complications are searched during the first days of life: hypertension, hypercalcemia, vomiting, hyperreninemia. Radical nephrectomy is performed after the end of the first week. In case of a classic form, the healing is always obtained. In case of cellular form, distant metastases are searched. In any rate, the follow-up is recommended until the end of the growth.


Sujet(s)
Tumeurs du rein/imagerie diagnostique , Néphrome mésoblastique/imagerie diagnostique , Abdomen/imagerie diagnostique , Abdomen/embryologie , Diagnostic différentiel , Femelle , Humains , Nourrisson , Nouveau-né , Tumeurs du rein/mortalité , Tumeurs du rein/anatomopathologie , Tumeurs du rein/chirurgie , Néphrome mésoblastique/mortalité , Néphrome mésoblastique/anatomopathologie , Néphrome mésoblastique/chirurgie , Grossesse , Troisième trimestre de grossesse , Résultat thérapeutique , Échographie
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